ライフサイエンスコーパス: completely

1 ating dimerization and self-renewal function completely.

2 nally led to a failure to clear the pathogen completely.

3 ve reduced localization efficiencies or fail completely.

4 awn tightly together to block ion permeation completely.

5 purified protein in vitro, this modification completely ablated the activity of LLO, and this inhibit

6 In 13 (33%; 95% CI: 18, 47) of 40 completely ablated tumors, intrahepatic tumor recurrence

7 gE and IgG to BGG was confirmed by ELISA and completely abolished after pre-incubation with alpha-gal

8 A missense change (S98R) in a case that completely abolished BAP1 deubiquitinase activity was id

9 topic activity, block of TGF-beta1 signaling completely abolished both arrhythmogenic conditions.

10 ments in the AD mice and this protection was completely abolished by inhibiting the dNGIs survival.

11 s mutation of Arg36 (R36W) or Arg35 (R35H/L) completely abolished DNA binding, mutation of Arg60 (R60

12 loop of phosphorylation site mutants nearly completely abolished HAC1 splicing, induction of KAR2, P

13 results demonstrated that MW thermal heating completely abolished honey antibacterial activity wherea

14 expression of single phosphomimic mutations completely abolished HTTex1 aggregation in human cells.

15 Both of these effects were almost completely abolished in cells from SNI-operated rats.

16 mouse models in which ERK/MAPK signaling was completely abolished in each of the two distinct classes

17 Treg depletion during iNKT infusions completely abolished iNKT efficacy in treating cGVHD.

18 ogic inhibition and genetic knockout of TLR4 completely abolished ML exosome-induced cytokine product

19 Pharmacological block of IA completely abolished rebound delays and, importantly, sh

20 ibition of alpha-glucosidase activity almost completely abolished residual glucose production by G6pc

21 mediated CCL2 knockdown in endothelial cells completely abolished the blood-brain barrier protective

22 e selection eliminated Runx3d expression and completely abolished the generation of CD8(+) single-pos

23 ne, with anti-MPO antibody treatment and was completely abolished with monocyte depletion.

24 athway and amelioration of ER stress in mice completely abolishes high fat diet-induced upregulation

25 In stark contrast, corrections were completely absent during the body-fixed task, despite th

26 tion results indicate that cohesin is almost completely absent from validated and predicted LDB1-regu

27 ic pathological features of INCL were almost completely absent in both the brain and spinal cord when

28 When SMC5/6 complexes were completely absent in oocytes during meiotic resumption,

29 wild-type (WT) rat, Cyp3a1/2 expression was completely absent in the liver of the KO rat.

30 nvelopes originating from GstDnaB1-300 could completely accommodate the GstDnaB C-terminal domain (re

31 lularization protocol enabled us to obtain a completely acellular renal scaffold while maintaining th

32 he uteri of neonatal FOXA2-deleted mice were completely aglandular.

33 awn as the studies performed so far were not completely analogous.

34 ted process to ensure that their genomes are completely and accurately replicated.

35 eatment of bran extracts of seven pigmented (completely) and non pigmented (sparsely) colored rice cu

36 DMS could not separate cis and trans isomers completely, as was the case with sphingomyelins, we reli

37 A nearly completely assembled metagenome, MGIIa_P, was recovered

38 These reactions are redox-neutral and completely atom-economical, exhibit broad functional gro

39 ter adjustment for cognitive decline but was completely attenuated after adjustment for cognitive per

40 Furthermore, knockdown of TLR8 completely attenuated collagen expression in monocytes e

41 R4 (6/6, P = 0.007), but not IDEC-131 (2/9), completely attenuated IgM antidonor alloantibody (alloAb

42 of the ATGC database), it is now built with completely automated methods and will be regularly updat

43 gas chromatography (mpGC) for continuous and completely automated process trace analytics exemplified

44 s the defense of modern text-based CAPTCHAs (Completely Automated Public Turing test to tell Computer

45 ional individual fetal brain MRI atlases for completely automatic multi-atlas segmentation of fetal b

46 AB, Q203 inhibited mycobacterial respiration completely, became bactericidal, killed drug-tolerant my

47 the blue part of the spectrum but has almost completely been ignored as potential photoswitch.

48 infusion of the ETA antagonist did not completely block the increase in blood pressure.

49 Maximal atropine pretreatment that completely blocked all the Cch-evoked responses did not

50 l was reduced by LJ001, transmission was not completely blocked at established antiviral doses.

51 Here, we show that binocular matching is completely blocked by monocular deprivation during the c

52 osis of POS by cultured RPE cells was almost completely blocked by pharmacological inhibition of phos

53 tagonist, dose-dependently and at high doses completely blocked ethanol-induced NREM sleep when admin

54 and tumor necrosis factor-alpha release was completely blocked in the absence of IL-1R.

55 ific depletion of TH from the culture medium completely blocked terminal erythroid differentiation an

56 -diisothiocyano-2,2'-stilbenedisulfonic acid completely blocked the CM-induced oxalate transport.

57 Treatment with MSC-Ex completely blocked the induction of inflammatory cytokin

58 ion of ROS scavenger N-acetyl cysteine (NAC) completely blocked these effects by S17 in MGC803 cells.

59 ility of 'zero-threshold' gain achievable by completely blocking the band-edge state with two electro

60 on of ictal discharges in some trials, while completely blocking them in others.

61 produces a leak of electrons to oxygen, and completely blocks the binding of UQ and the inhibitor HQ

62 on of cell viability and tumor formation was completely blunted by blockade of beta-adrenergic signal

63 r trapped air pockets so quickly that it can completely bounce off the surface.

64 memory devices, sensors, and diodes that are completely built from soft materials.

65 when mislocalized, both LolA and LolB can be completely bypassed by activating an envelope stress res

66 itidis after incubation with human serum was completely C3-dependent, as detected by flow cytometry.

67 ine eutectic decreased with cooling rate and completely ceased to exist at cooling rates greater than

68 cused on social networks, and have assumed a completely censused network.

69 Here we use gate set tomography to completely characterize operations on a trapped-Yb(+)-io

70 ns and phenolic compounds that have not been completely characterized.

71 ng candidate medical countermeasures may not completely clear EBOV infection.

72 metry, the precise mechanism of which is not completely clear.

73 rous failure, but its mechanism is still not completely clear.

74 trikingly, the polypeptide-binding pocket is completely closed, seemingly excluding any substrate bin

75 ificantly mutated (or undermutated) genes is completely confounded by the genomic heterogeneity of ca

76 ulates metamorphosis when provisions are not completely consumed.

77 , type, and extent of the modifications were completely controlled by solvent composition, laser wave

78 synthesize from oligodeoxyribonucleotides a completely de-novo-designed, 58-kb multigene DNA.

79 Yet the recombinant virus remained completely defective for productive replication, providi

80 echanisms underlying these processes are not completely defined.

81 his study was to evaluate the degradation of completely demineralized dentin specimens in contact wit

82 Permeabilization activity is completely dependent on the disulfide bond between the t

83 romosome segregation and survival, which was completely dependent on the temperature and mito-nuclear

84 Viruses are completely dependent upon cellular machinery to support

85 he synergistic effect of LTC4 with IL-33 was completely dependent upon CysLT1R, because CysLT1R(-/-)

86 and cell-free expression technologies, even completely detergent-free membrane protein characterizat

87 o the amino-terminus that collectively could completely determine the different effects of physostigm

88 idence suggests that the IgG2 isotype is not completely devoid of effector function, whereas the IgG4

89 Many species are completely devoid of selenoprotein genes and lack the ab

90 M175, the architecture of which represents a completely different fold from that of canonical K(+) ch

91 erate resistance to unrelated pathogens with completely different lifestyles and routes of invasion.

92 A completely different paradigm is based on three-terminal

93 We report here that targeting a completely different process, autophagy, can overcome mu

94 subjects' violent ideation at baseline were completely different than their subsequent targets of vi

95 t ions arising from (2)H-labeled tracers are completely differentiated from those arising from (13)C-

96 tinal nuclear receptor corepressor 1 (NCoR1) completely diminishes hyperbilirubinemia in hUGT1 neonat

97 5P abrogates the PALB2-BRCA1 interaction and completely disables its abilities to promote HR and conf

98 ceived sizable industry payments and did not completely disclose these payments.

99 orest development and it was not possible to completely disentangle their effects.

100 teins have shown natural abundance of either completely disordered proteins that are recognized as in

101 icking Atf1 mutant, the presence of Sty1 was completely dispensable, with all stress defects of Sty1-

102 acid impurities, cadmium carboxylate can be completely displaced from the surface using n-alkylamine

103 on with the Gal80 inhibitor specifically and completely disrupted memory.

104 obable DLB group, and medial temporal uptake completely distinguished AD dementia from probable DLB.

105 eta deleterious effect does not appear to be completely driven by metabolic changes.

106 sponses compared to soluble trimers, it also completely eliminated antibodies directed to the C-termi

107 in solvent exposed regions, they were almost completely eliminated from buried sites.

108 aggregates and Het-s fibrils, but virtually completely eliminated in Het-s/GroEL fibrils, suggesting

109 ression, the remaining structures are either completely eliminated or converted into functional skin

110 the insulin-secreting MIN6 cell line almost completely eliminates insulinotropic activity of M3R.

111 istence of mobile COPII-coated vesicles that completely encapsulate the cargo PC1 and are physically

112 onjunction with the antibiotic ciprofloxacin completely eradicates UPEC from the urinary tract and pr

113 These findings were not completely expected based on known temporal and qualitat

114 PN1 function could contribute to but may not completely explain the pathology detected in Pabpn1+/A17

115 Outcomes are not completely explained by agricultural performance or the

116 By contrast, heterozygous mpk6 mutant plants completely failed to produce homozygous mpk6 seeds.

117 uccessfully generate digitized filling flow, completely free from errors due to changes in viscosity.

118 The pressure of 600MPa completely gelatinized quinoa starch as revealed by ther

119 The methods described are completely generalizable to many nucleic acid biomarkers

120 ddition of monensin, a Na(+)/H(+) exchanger, completely halts the infection.

121 The hybrid mimics are almost completely homozygous with chromosome segments from each

122 Yet, the cutinase completely hydrolyzed all PBAT films, including films wi

123 nces from cART-treated individuals that were completely identical, consistent with clonal expansion o

124 other effect of electromagnetic radiation is completely impossible.

125 typically decreases with pH and often ceases completely in slightly acidic wastewaters.

126 lear the transmissible stage of the helminth completely in treated individuals.

127 S. bayanus cells were completely inactivated in 10 passes without temperature

128 PPO was completely inactivated in 20min at 85 degrees C, however

129 ng its replication, whereas 21-3U was almost completely inactive.

130 This would be completely incompatible with survival without the presen

131 Such OAM is a completely independent degree of freedom which can be re

132 n where internal nutrient concentrations are completely independent of external nutrient concentratio

133 Here, we reveal that voltage clamp is completely ineffective for most excitatory synapses due

134 ffects on bile acid kinetics in WT mice, but completely inhibited active transport of conjugated bile

135 Acute alcohol treatment (25 mm) completely inhibited hormone-induced calcium increases i

136 O3 greater than 0.08%w (%w = weight percent) completely inhibited microbial growth (from 1.4 x 10(7)

137 gnificantly attenuated by DHA, and letrozole completely inhibited this suppressive action.

138 ng from NOTCH2 signaling was reduced but not completely inhibited, in response to JAG1(Ndr) compared

139 tion-stimulated glucose transport was almost completely inhibited.

140 s chinensis (Coleoptera) alpha-amylases were completely inhibited.

141 .0 g/L nZVI at which bacterial viability was completely inhibited.

142 e growth medium allowed the fungus to regain completely its ability of aflatoxin biosynthesis.

143 luids show promising hyperthermia effects to completely kill the tumors.

144 inhibitors of Tyr181Cys RT (CRTIs) that can completely knock out activity of the resistant mutant an

145 occurs under pathological conditions is not completely known.

146 0Rbeta), is a cytokine whose function is not completely known.

147 Nearly all Ensifer meliloti strains completely lack ebpA, tcrA, tcsA and fsrR regulatory loc

148 bryonic stages of hemimetabolous insects are completely lacking.

149 tion in auditory generalist avian species is completely lacking.

150 sculature, the temporal pole is not commonly completely lesioned in stroke survivors and this heterog

151 A protein forced to be continuously unfolded completely loses its ability to contract by folding, bec

152 essing Lin37 proliferate normally, but DREAM completely loses its ability to repress genes in G0/G1 w

153 High AST completely mediated the HBV infection-any cataract assoc

154 cating a greater temperature was required to completely melt all of the fat.

155 cases the evidence is inconclusive: no model completely mimics Barrett's oesophagus in terms of the p

156 tion of endogenous SUMOylated proteins under completely native conditions.

157 ; excluded from survival analysis); low risk/completely necrotic (n = 7; zero relapses), intermediate

158 nged the membranes' dynamic behavior, almost completely negating the previously observed effect of te

159 Mechanisms for the emergence of completely new active sites must therefore either plausi

160 mponent, and audio-visual stimuli containing completely new auditory and visual material.

161 y CellNet to RNA-seq data and how to build a completely new CellNet platform applicable to, for examp

162 cial nanofluidic devices have stepped into a completely new stage, termed 2D nanofluidics.

163 We find, however, that the spicules use a completely new strategy.

164 uses with previous paradigms or to propose a completely new vision of the living world.

165 In this study, we developed a completely non-destructive strategy using HS-27, a fluor

166 into partially novel transcripts (PNTs) and completely novel transcripts (CNTs) (novelty score >/= 7

167 Tibial artery vessels were classified as completely occluded, significantly stenosed (>/=50%), or

168 These cost reductions may completely offset the cost of the drug once ezetimibe be

169 arious treatment options are available which completely or at least partially reduce the number or du

170 promoted glycosylation was also proven to be completely orthogonal to the gold-promoted glycosylation

171 China, which preserves a unique example of a completely ossified otoccipital division of the braincas

172 model the overall change of a gene set, yet completely overlooked heterogeneous time-dependent chang

173 sulting in formation of photoactive OCP from completely photoinactive species.

174 ochemical data indicate that the SBT core is completely planar, likely via S(alkyl)cdots, three dots,

175 amolecular secondary Se...N interactions, is completely planar.

176 the micropillar's structural characteristics completely predetermined, leaving little room for in sit

177 AUT1 completely prevented amphetamine-induced hyperactivity i

178 on-hydrolyzable PGE2-serinol amide, and were completely prevented by methyl-arachidonoyl-fluorophosph

179 stimulation divided in three spaced stimuli completely prevented it.

180 t; pharmacologic inhibition of these kinases completely prevented Siglec-8-mediated eosinophil apopto

181 AraC treatment completely prevented the increase in number of activated

182 the onset of the disease and in some animals completely prevents the development of clinical symptoms

183 ces phosphorylation of Smad3, and PNS nearly completely prevents this effect.

184 th a cocktail of six different vaccines were completely protected from challenge with individual viru

185 utralizing in vitro Nevertheless, the H7 WIV completely protected mice against homologous viral chall

186 sed to Pneumocystis murina Pca1 immunization completely protected nearly all mice, similar to immuniz

187 e injected with anti-mLAMalpha3 F(ab')2 were completely protected.

188 coding ZIKV pre-membrane and envelope (prME) completely protects mice against ZIKV-associated damage

189 , neutralizes influenza in cell culture, and completely protects mice when given as a single dose 24

190 cient electron equivalents were available to completely reduce NOx to N2, resulting in increased N2O

191 We implemented a completely refactored version of the RankProd package, w

192 A BSG knockout was completely refractory to parasite invasion in a strain-t

193 in a cascade SN2'-6-endo-trig fashion and is completely regioselective and highly stereoselective.

194 Bitter tastants can completely relax myometrium precontracted by different u

195 lex is highly pH-dependent; the phosphate is completely released from Gd-TREN-MAM below pH 2.

196 genomic environmental DNA studies are almost completely reliant on next-generation sequencing, making

197 echanisms to stall developmental pathways or completely remove defective cells from a population is a

198 substitutions in the linker domains of GluA2 completely removed any effect of gamma2 on receptor kine

199 reptavidin plus the biotinylated bait can be completely removed by 3min injections of biotin, guanidi

200 olution-phase ligand exchange methods, which completely replace native ligands with functionalized ci

201 s of Jam 2 and 3, while in Jam 4 sucrose was completely replaced by fructose and stevioside, making t

202 inelandii siderophore vibrioferrin is almost completely repressed under Mo- and V-limitation.

203 The ETO-induced block was completely rescued by depletion of SAMHD1 in MDM Concord

204 the respiratory phenotype, which was instead completely rescued by expressing the wild-type allele.

205 acids in IR25a and IR76b mutant flies can be completely rescued by expression of respective transgene

206 persensitivity to hematopoietic ablation was completely rescued by inactivation of p53.

207 ges associated with mutant Nlrp3 were almost completely rescued by Tnf knockout in association with a

208 The mutant phenotype was completely rescued by transgenic expression of AtHEMN1 P

209 This phenotype was however completely rescued on activation of ER stress by additio

210 Finally, systemic deletion of Cldn14 completely rescued the hypercalciuric and lower serum ca

211 fully reverses hippocampal synapse loss and completely rescues preexisting behavioral deficits by 17

212 oup performance status of 0 or 1 and who had completely resected stage IB (>/=4 cm) to IIIA (defined

213 rial, we randomly assigned 870 patients with completely resected, stage III melanoma with BRAF V600E

214 low frequencies in the nondiseased CNS, are completely resistant to EAE development following adopti

215 alanine mutation in LLO rendered the protein completely resistant to inactivation by S-glutathionylat

216 todes treated with the peptide at 0.1 nM are completely resistant to killing by C. albicans The pepti

217 in 2 patients in the control group and were completely resolved after switch.

218 er, at 7 days airway hyperresponsiveness had completely resolved in Darc(E2) but persisted in WT mice

219 However, the thermal mismatch is not completely resolved in highly mismatched systems such as

220 had grade 3 or 4 neurologic toxicities that completely resolved.

221 PG)-immunoglobulin fragment complex (OPG-Fc) completely restore the function of fast-twitch extensor

222 TP production), insulin secretion was almost completely restored at elevated glucose concentrations.

223 cits we observed in mouse prion disease were completely restored by treatment with benzyl quinolone c

224 A DeltaciaRDeltaargB double mutant was completely restored for the gtfP gene expression, glucan

225 Blocking IDO1 activity completely restored Th cell proliferation, but not IFN-g

226 ype HFD donor mice into HFD Bnull recipients completely restored the effect of HFD to induce insulin

227 rade and thus normal mineral volume is never completely restored.

228 any PLT clade member in the mutant primordia completely restores layer identities at stage II and res

229 W350-UO at a 20 wt % application rate almost completely retained the pathogenic E. coli in the subsur

230 the inactivation of phoP, phoQ or Sant_4061 completely retards the growth of S. praecaptivus in the

231 for two macronutrients together to negate or completely reverse the impact of applying either one alo

232 , molecular and functional readouts were not completely reversed by ammonia-lowering measures.

233 Dietary iron repletion completely reversed ID anemia and ineffective erythropoi

234 utant zebrafish rescue with human EXOC5 mRNA completely reversed the mutant phenotype.

235 The original code of PyMod has been completely rewritten and improved in version 2.0 to exte

236 temporal lobe epilepsy will not be rendered completely seizure-free after temporal lobe surgery.

237 ithin the homodimeric Fc polypeptide, enable completely selective binding to the complement component

238 racterised by a migration time of 54s, which completely separates it from EOF.

239 nd function of protein-coding genes from 104 completely sequenced genomes.

240 the characteristic ring-opening reaction is completely silenced, which explains that the majority of

241 the brain, where the exon is normally almost completely skipped.

242 of this incorporation are materials that are completely soluble in mildly acidic solutions but precip

243 We challenge this assumption, showing that completely spinalized adult rats can recover unassisted

244 uidic chips can function to controllably and completely stretch lambda DNA in a two-dimensional nanof

245 tes, whereas the Er:YAG laser (38.2 J/cm(2)) completely stripped away the plaque and TiO2 layer, leav

246 nd that caspase and RIPK3 inhibitions do not completely suppress cell death in Tak1-deficient cells.

247 of cGVHD ameliorated by BCL6 deficiency and completely suppressed by Stat3 deficiency in donor CD4(+

248 nels and global deletion of CaV 3.1 channels completely suppressed development of long-term potentiat

249 find the hydrogen evolution reaction can be completely suppressed even at high overpotentials (-400

250 ever, these changes were attenuated, but not completely suppressed in gene-deficient mice, especially

251 suggest that activation of C5 is not always completely suppressed in patients even under excess of e

252 of amine end-functionalized polystyrene are completely suppressed, allowing the jetting of aqueous t

253 between certain combinations of antibiotics completely suppresses the development of resistance to o

254 nockdown of PRMT5 in AR-positive LNCaP cells completely suppresses the growth of xenograft tumors in

255 The most active peptide was completely symmetrical, rich in Arg and Trp residues, an

256 Whitney U, P = 0.037) as well as confounding completely the effect of FA on multivariate survival ana

257 at its predictive power disintegrates almost completely through the causal chain underlying aggressio

258 far more students than having a few faculty completely transform their teaching, but the extent to w

259 Strikingly, hH3R365 was completely unable to stimulate GSK3beta phosphorylation,

260 Similarly, optic nerve regeneration was completely unaffected, although repopulation of the lesi

261 he exact pathophysiological mechanism is not completely understood and remains controversial at prese

262 However, it is not completely understood to what extent this is the case.

263 However, the ESI process is still not completely understood, and it is often a matter of trial

264 ptional regulation of these cytokines is not completely understood.

265 e developed, NEC pathophysiology can be more completely understood.

266 glycemia and atherothrombotic disease is not completely understood.

267 can be protective, but the mechanism is not completely understood.

268 ow Treg cells maintain their identity is not completely understood.

269 horylation in this process, however, are not completely understood.

270 to actin cytoskeletal reorganization is not completely understood.

271 s is determined by different antigens is not completely understood.

272 transfer process, however, have not yet been completely understood.

273 ar mechanisms behind this phenomenon are not completely understood.

274 l response of the memory cells are still not completely understood.

275 nal transplantation (ITX) are far from being completely understood.

276 ric chromatin from general chromatin are not completely understood.

277 nulocyte-macrophage progenitor are still not completely understood.

278 eletal muscle atrophy, but their role is not completely understood.

279 ever, the mechanisms for HA35 action are not completely understood.

280 creatic alpha cell mass and function are not completely understood.

281 ction of L1s in host gene regulation are not completely understood.

282 But these structural features are not completely understood.

283 at are involved in WNV neuroinvasion are not completely understood.

284 conditions, although the mechanisms are not completely understood.

285 d the development of atherosclerosis are not completely understood.

286 in the Drosophila FXS model, we discovered a completely unexpected and highly robust neuronal dye ion

287 th, and while most of this diversity remains completely unexplored, advances in genome sequencing hav

288 nderlying the surface dynamics of CaV1.2 are completely unexplored.

289 PCa)-the most common cancer type in males-is completely unexplored.

290 y called a non-canonical CTD, which performs completely unknown functions.

291 in episomes versus chromosomes remain almost completely unknown.

292 ique network of field sites which are either completely unlit (control), or are artificially illumina

293 atients, one consisting of patients who were completely unmedicated and the other consisting of patie

294 ed, a small electron pocket in YbAl3 becomes completely unoccupied while the low-energy ytterbium (Yb

295 e of 1.54 g g(-1), and its structure remains completely unperturbed upon inclusion/removal of I2.

296 typical pathways, including several that are completely unprecedented for bacteria or any organism.

297 sR and CrsA control sigma(S) activity is not completely unveiled.

298 rs in positions can be corrected essentially completely with little added computational cost.

299 3 precipitation does not fill the pore space completely, with the result that acidic brine continues

300 will likely be drawn upon when all OPVs are completely withdrawn after polio eradication, but also m