ライフサイエンスコーパス: completely abrogate

1 ation in response to chemotactic stimuli was completely abrogated.

2 nd flow-induced hyperpolarization was almost completely abrogated.

3 nt apoptosis, whereas p75-mediated death was completely abrogated.

4 d50 and Nbs1; however, nuclease activity was completely abrogated.

5 The aae apiA double mutant completely abrogated A. actinomycetemcomitans binding to

6 In contrast, Cdk2 deficiency completely abrogates aberrant centrosome duplication ind

7 lization or genetic deletion of MIF does not completely abrogate activation responses, however, and d

8 st, depletion of Thy1+ innate lymphoid cells completely abrogated acute and chronic innate colitis.

9 both donor Fas expression and CD4 T-cell PFP completely abrogated acute rejection, despite the persis

10 flavoenzyme inhibitor (diphenyleneiodonium) completely abrogated Ag-induced dichlorodihydrofluoresce

11 as the activity of anti-PD-L1 antibodies was completely abrogated against large tumors.

12 The Lys mutations reduced, but did not completely abrogate, agonistic action of IL-1beta.

13 n L in a model of experimental asthma almost completely abrogated airway hyperresponsiveness and eosi

14 TAPI-1 (an ADAM inhibitor) completely abrogates all observed shedding and the produ

15 The early apoptotic response was almost completely abrogated, although elevated levels of delaye

16 Mutation of Tyr-267 completely abrogated and mutation of Tyr-363 reduced Ack

17 ), selective migration of T cells in vivo is completely abrogated and that T-bet regulates the bindin

18 y effects of valsartan and the highest doses completely abrogated angiotensin II-mediated effects.

19 ion by over 90%, while proteasome inhibitors completely abrogated antigen presentation.

20 siRNA knockdown of DDIT4 completely abrogated antiproliferative responses to 1,25

21 nd caspase activation because scavenging ROS completely abrogated apical caspase-8 activation and fur

22 ng beta1 integrin with small interfering RNA completely abrogates Arg-dependent cortactin phosphoryla

23 art and skin tissues, but not joint tissues, completely abrogating arthritis virulence.

24 ctor-alpha-stimulated endothelium was almost completely abrogated, as observed in flow chamber adhesi

25 hat the removal of any phenylalanine residue completely abrogates assembly ability, while charged res

26 but not pan-caspase or paspase-9 inhibitors, completely abrogated atiprimod-induced apoptosis.

27 orylation, and paxillin expression knockdown completely abrogated bacteria-induced motility.

28 thanocaldococcus jannaschii (Mja) TBP do not completely abrogate basal transcription.

29 Inhibition of nitric oxide signaling completely abrogated basal MYPT1 Ser-695 phosphorylation

30 l that allows for their conditional ablation completely abrogated basic fibroblast growth factor-indu

31 letions of the canonical GATA1 binding motif completely abrogated binding of the cofactor TAL1, which

32 nd in corresponding positions in PKG Ialpha, completely abrogated binding to TFII-I and IRAG without

33 (PKC) with chelerythrine (CHE, 2 micromol/L) completely abrogated both PC (38+/-2% vs. CHE alone, 35+

34 This effect was completely abrogated by a constitutively active form of

35 nd this effect was dependent on PKA, and was completely abrogated by a dominant-negative form of CREB

36 This binding was completely abrogated by a point mutation (G1690A) in the

37 type III IFNs by B. burgdorferi RNA could be completely abrogated by a TLR7 inhibitor, IRS661.

38 These effects of metformin were mimicked or completely abrogated by adenoviral overexpression of a c

39 These effects of metformin were mimicked or completely abrogated by adenoviral-mediated expression o

40 amage in E. coli K1-infected mice, which was completely abrogated by AG administration.

41 adhesion molecule-1 (MAdCAM-1) and this was completely abrogated by anti-alpha4beta7 (hybridoma clon

42 IL-17 production was completely abrogated by anti-IL-1 or IL-1 receptor antag

43 er, trappin-2-enhanced clearance of PA01 was completely abrogated by CD14- null macrophages.

44 These abnormalities are completely abrogated by coexpression of wild-type PrP fr

45 greatly reduced by Kir channel blockade and completely abrogated by concurrent cyclooxygenase inhibi

46 4 T cells in response to virus challenge was completely abrogated by CTLA4Ig with IFN-gamma productio

47 activates NF-kappaB, and this activation was completely abrogated by DIM treatment.

48 oplatelet formation, an effect that could be completely abrogated by DKK1.

49 D38 expression induced by TNFalpha alone was completely abrogated by fluticasone (100 nM), dexamethas

50 r localization of Gli1 in MM cells, which is completely abrogated by Forskolin, a Gli1-modulating com

51 This response was completely abrogated by hypertonic saline.

52 signaling on nonhematopoietic cells and were completely abrogated by IFN-I receptor blockade.

53 4(+) lymphoid tissue inducer (LTi) cells was completely abrogated by IL-7Ralpha blockade.

54 TRALI induction by intact antibody was completely abrogated by in vivo peripheral blood monocyt

55 ctivity could be progressively inhibited and completely abrogated by increasing genetic impairment of

56 comitant increase in insulin endocytosis was completely abrogated by inhibiting the transport activit

57 ylation, and PKCepsilon gene repression were completely abrogated by knockdown of Nox1 in cardiomyocy

58 These effects on proliferation were completely abrogated by mutating either the active site

59 uminescence quantification and survival) was completely abrogated by passive immunization with high-t

60 The processing was completely abrogated by pepstatin A, a specific inhibito

61 s strictly dependent on C5aR, because it was completely abrogated by PMX-53, a C5aR antagonist.

62 in knockdown in vitro, and these effects are completely abrogated by the activation of S1P/S1pr2 sign

63 This induction was completely abrogated by the inhibition of protein kinase

64 The labeling of [14C]ceramide was completely abrogated by the SPT inhibitor ISP-1.

65 roteolytic activation of plasminogen and was completely abrogated by the urokinase plasminogen activa

66 by BLyS stimulation, but this protection is completely abrogated by treatment with the mTOR inhibito

67 ze and transmitter release in CK mutants are completely abrogated by: a) reduced activity of motor ne

68 cancer cells alone was sufficient to almost completely abrogate cancer progression and lung metastas

69 nockdown experiment, indeed, TAp73 depletion completely abrogates cancer cell proliferation capacity

70 The loss of CD151 trafficking completely abrogated CD151-promoted cell migration on ex

71 markably, the absence of GITR in mice almost completely abrogates cellular expansions, splenomegaly,

72 d mutation of the canonical Myb binding site completely abrogated CGRE enhancer activity.

73 sociated with significantly reduced, but not completely abrogated choline transporter function.

74 mutants further exacerbates TZ anomalies and completely abrogates ciliogenesis.

75 FAK small interfering RNA completely abrogated class I-mediated formation of actin

76 enzymic activity in NS cell-containing gels completely abrogated collagen-contraction-induced-apopto

77 nd Cox12/COX6B, a structural subunit of CcO, completely abrogates Cox2 biogenesis.

78 PEGylation completely abrogated coxsackievirus and adenovirus recep

79 cyclin-dependent kinase phosphorylation site completely abrogates Crb2 IRIF and function.

80 ) or third (i3) intracellular loops of CXCR4 completely abrogate CXCL12-mediated cell migration of ly

81 However, such hepatic p97 knockdown almost completely abrogated CYP3A extraction into the cytosol,

82 STAT3 inhibitors completely abrogated cytokine-induced translocation of F

83 ade markedly reduced cardiac arrhythmias and completely abrogated deaths due to severe hypoglycemia.

84 , overexpression of either NFkappaB or Snail completely abrogated deguelin-mediated epithelial-to-mes

85 s and reduced lifespan of mature B cells and completely abrogated development of B-cell lymphoma.

86 loss of TLR4 solely in CD4(+) T cells almost completely abrogated disease symptoms, mainly through bl

87 of the majority of this region (Delta86-246) completely abrogated dsRNA binding.

88 d that knockdown of critical autophagy genes completely abrogated EC survival.

89 The study showed that the vATPase inhibitor completely abrogated epithelial cell infection, virus sh

90 ggregation, and blocking Src kinase activity completely abrogated ERK1/2 activation and uPA induction

91 Point mutations in this Galphaq region completely abrogate ERK5 phosphorylation, indicating tha

92 Furthermore, deletion of Stat5 completely abrogated erythropoietin (Epo)-independent er

93 (GFP+) MOG-35-55-reactive T-cells and almost completely abrogated existent GFP+ cellular infiltrates

94 m targets showed that vemurafenib (480 mg/d) completely abrogated extracellular signal-regulated kina

95 ts and IMR90 fibroblasts, an effect that was completely abrogated following mutation of the E2F sites

96 rated that the CcpA DNA binding activity was completely abrogated for the phosphorylated CcpA.

97 , located within the short cytoplasmic tail, completely abrogated function, indicating that the gH cy

98 essive shortening of this segment reduced or completely abrogated fusion trigger function, while leng

99 utilization, but MalE inactivation does not completely abrogate GAS catabolism of maltose or maltotr

100 ding Ulex europaeus agglutinin I (UEA-I) was completely abrogated, GDP-Fuc was still detected in the

101 f FLT3 mutations or wild-type FLT3 (FLT3-WT) completely abrogates hematopoietic differentiation from

102 Finally, E2f1 deletion completely abrogated hepatic steatosis in different muri

103 eas neutralizing both syndecan-3 and DC-SIGN completely abrogated HIV-1 capture and subsequent transm

104 mediate early viral proteins, ICP4 or ICP27, completely abrogated HSV-1 infection.

105 mid containing the MIE genomic locus did not completely abrogate IE1 and IE2 expression.

106 imultaneous inhibition of both TLR7 and TLR9 completely abrogated IFN-alpha induction.

107 unctional studies using blocking Abs to CD25 completely abrogated IFN-gamma production by the CD8(+)

108 f lipid rafts using methyl beta-cyclodextrin completely abrogated IFN-gamma-induced Hsp72 release.

109 rior to intrasplenic injection into NSG mice completely abrogated IL-15 superagonist-mediated suppres

110 sly to be important for NFkappaB activation, completely abrogated IL-6 promoter activation in respons

111 of both the acidic loop and the beta-hairpin completely abrogates IL-12 secretion.

112 Inhibition of STAT3 activation completely abrogates IL-27-induced upregulation of B7-H1

113 Both of these effects were completely abrogated in AID-deficient B cells.

114 in acute forebrain slices from D36 mice but completely abrogated in AKAP5 KO mice.

115 rated that NPI-0052-induced cytotoxicity was completely abrogated in an Akt knockdown cell line, indi

116 adiated bystander cells, but this effect was completely abrogated in ATR and ATM but not DNA-PK-defic

117 st to IgG, the therapeutic effect of IgM was completely abrogated in C3-deficient mice.

118 pressing a dominant-negative mutant IRF3 and completely abrogated in cells lacking IRF3.

119 kappaB inducing activity of these agents was completely abrogated in cells pretreated with genistein.

120 cytoskeletal responses to exogenous PA were completely abrogated in cp mutants.

121 alpha-induced neutrophil adhesion was almost completely abrogated in E-selectin(-/-) mice treated wit

122 These E2-induced effects were completely abrogated in ERalpha-deficient mice, showing

123 r complement receptor 3 (CR3) but was almost completely abrogated in FcgammaR I/III-deficient mice.

124 size in wild-type mice, but this effect was completely abrogated in HO-1(-/-) mice.

125 Remodeling was completely abrogated in IL-10-/- mice, suggesting that a

126 s and lung infiltration by immune cells were completely abrogated in infected Myd88/Trif/Mavs(-/-) mi

127 ptional responses and IFN-beta secretion are completely abrogated in MAVS/IPS-1(-/-) MEFs.

128 ion of T-bet and IFN regulatory factor-1 was completely abrogated in me(v)/me(v) CD4+ T cells.

129 adjuvant effect of cell-associated dsRNA was completely abrogated in mice deficient in TLR3 or type I

130 OVA-induced AHR was partially or completely abrogated in mice haploinsufficient for ROCK2

131 tions in skeletal muscle insulin action were completely abrogated in mice lacking Sirt1 deacetylase a

132 egulation of Acta2 in the infarct region was completely abrogated in p21-deficient mice.

133 tion is delayed in Ascl1 knock-out OE and is completely abrogated in p63-null mice.

134 the kinetics of p44/42 phosphorylation were completely abrogated in Rh1mTORrr cells that express a r

135 n wild-type C57B mice was broadly and nearly completely abrogated in RLIP76(-/-) mice.

136 iated down-regulation of VLA-4 expression is completely abrogated in Stat6-deficient CD8+ T cells.

137 sal immunization with whole-cell vaccine was completely abrogated in T cell-deficient mice, and in mi

138 We found that clonal deletion to TRA was completely abrogated in the absence of Bim and large num

139 theroprotective effect of DNGR-1 deletion is completely abrogated in the absence of bone marrow-deriv

140 and growth-inhibitory actions of IGFBP-3 are completely abrogated in the absence of catalytically act

141 Regional activation of these products was completely abrogated in the absence of Math1.

142 nished in the Cdk4+/- genetic background and completely abrogated in the Cdk4-/- background.

143 In MEL28 cells, CDK2 activity is completely abrogated in the inner regions of the spheroi

144 ium-regulated changes in gene expression are completely abrogated in the mutant, indicating that, sim

145 nt CD8(+) Tem, T effector cell expansion was completely abrogated in the TDLN, revealing that restora

146 duced levels of 3'NT/NU enzyme activity were completely abrogated in these transfected cells versus c

147 TNF-mediated Phex down-regulation was completely abrogated in vitro by PARP-1 inhibitor and ov

148 y activated Treg cells, whereas its blockade completely abrogated inhibition by Treg cells.

149 Metformin pretreatment completely abrogated insulin-induced potentiation of Ca(

150 residues in viruses encoding full-length NSs completely abrogated intranuclear filament formation in

151 with neutralizing mAb or depletion of Hsp72 completely abrogated its chaperokine function.

152 In contrast, removal of sialic acid completely abrogated its inhibitory ability.

153 antagonist before 15d-PGJ(2) administration completely abrogated its protective effect against influ

154 substantially decreased its aggregation and completely abrogated its toxicity in cell lines and moto

155 tion site in the FERM domain of JAK3 (Y100C) completely abrogated JAK3-mediated leukemic transformati

156 etion of the 20 C-terminal amino acids of E5 completely abrogates koilocytosis, whereas a 10-amino ac

157 the combined deficiency in PSGL-1 and ESL-1 completely abrogated leukocyte recruitment.

158 Leu514 and either Leu293, Lys294, or Arg491 completely abrogated LF toxicity, pairwise mutation of L

159 paired sympathomimetic (methamphetamine) and completely abrogated lipopolysaccharide (LPS) thermogene

160 on of the Ubc9-LMP1 CTAR3 interaction almost completely abrogated LMP1-induced protein sumoylation, s

161 ckade of PI3K/Akt and MEK1/2 kinase pathways completely abrogated lung injury.

162 Deletion of both DAP10 and DAP12 completely abrogates Ly49H surface expression and contro

163 clearance, the lack of both receptors almost completely abrogates macrophages' ability to scavenge CE

164 lanine aminotransferase and microRNA-122 and completely abrogated markers of APAP-induced inflammatio

165 eletion of an N-terminal lipid-binding motif completely abrogates membrane interaction and in vivo fu

166 Combination of gemcitabine and cyclopamine completely abrogated metastases while also significantly

167 d mutator phenotype in Escherichia coli, but completely abrogates mismatch repair activity in Bacillu

168 thetic lethality of pol2-4 with alleles that completely abrogate MMR (msh2Delta, mlh1Delta, msh3Delta

169 e di-glycine motif or the terminal glutamine completely abrogated modification of cellular proteins w

170 M)beta(2)/GPIbalpha and to PSGL-1/P-selectin completely abrogates MP-induced platelet activation.

171 r necrosis factor alpha, by reducing but not completely abrogating NF-kappaB-induced transcription.

172 TR-Chk1 pathway in Tim-Tipin-deficient cells completely abrogates nucleotide incorporation in S phase

173 s onzin is coexpressed, in which case PLSCR1 completely abrogates onzin's positive effects on prolife

174 Treatment with TAT-ARC protein completely abrogated otherwise lethal liver failure indu

175 timulation of Smad2/3, this TbetaR-II mutant completely abrogated p38 MAPK activation by TGF-beta.

176 athway, and inhibition of the 26S proteasome completely abrogates Parkin-mediated mitophagy in HeLa,

177 Deficiency of the dectin-1 receptor completely abrogated particulate beta-glucan-mediated an

178 ions (A242C, R245C, K252C, and Y255C) with a completely abrogated PD activity.

179 because reduction of its two disulfide bonds completely abrogated peptide activity.

180 n of the region surrounding these insertions completely abrogated pilin Av, confirming that specific

181 otein levels or ablating the endocytic motif completely abrogated PKC-regulated KCNK3 trafficking.

182 pression of CD25, and neutralization of IL-2 completely abrogated productive HIV infection in vitro.

183 nd combinatorial mutation of all three sites completely abrogated promoter activity to background lev

184 CD8(+) T cells in solidly protected macaques completely abrogated protective immunity.

185 have been discovered that reduce, but do not completely abrogate proximal TCR signaling.

186 promised in DARC knockout mice, whereas KAI1 completely abrogated pulmonary metastasis in wild-type a

187 histocompatibility complex (MHC) protein may completely abrogate recognition of the peptide-MHC (pMHC

188 Captopril also completely abrogated renin stimulation in wild-type mice

189 Asn-110 replacement with Gln completely abrogated rhDAO secretion and caused retentio

190 e sole determinant because deletion does not completely abrogate ribosome binding.

191 n of the combination of KH3 and KH4 domains, completely abrogated RNA binding in vitro and significan

192 Treatment with anti-CD40 completely abrogated sepsis-induced splenic B cell death

193 One of these peptides completely abrogated SEVI-mediated enhancement of HIV-1

194 loying a knock-in mutation (Kit(Y719F)) that completely abrogates signaling via PI3K.

195 class I and MHC class II Ag presentation was completely abrogated similar to FcRgamma(-/-) DCs.

196 ddition, pharmacological inhibition of Duox1 completely abrogated skin inflammation, placing Duox1-de

197 g out the DNA sensor cyclic GMP-AMP synthase completely abrogates spontaneous induction of IFN-stimul

198 A interference or antisense oligonucleotides completely abrogates steroid-triggered meiotic resumptio

199 n of the cleavage site in the CDCP1 molecule completely abrogated survival signaling associated with

200 esion studies also showed that loss of Itgb2 completely abrogated T-cell adhesion.

201 r, this shRNA tbeta4-knockdown model did not completely abrogate Tbeta4 expression.

202 g RNA targeting AREG attenuated, but did not completely abrogate the growth-promoting effects of sene

203 prevention of T-cell entry to all SLOs could completely abrogate the onset of aGVHD.

204 cases, blockade of B7H1 or B7DC was able to completely abrogate the TAF-mediated suppression.

205 3 immune complex with recombinant mouse CD64 completely abrogated the A1H3-mediated enhancement of th

206 Notably, actinomycin-D completely abrogated the ability of AF to downregulate H

207 rine (PS) from both populations of liposomes completely abrogated the ability of all three isoforms o

208 substitution of either arginine with alanine completely abrogated the ability of CouR to bind DNA.

209 YC-1, HIF-1alpha inhibitor, completely abrogated the actions of CO on VEGF induction

210 Mutation at the target site completely abrogated the activity of miR-650 on the 3' u

211 nsertions at residues 387, 420, 474, and 502 completely abrogated the activity.

212 cy upon the background of insulin resistance completely abrogated the adaptive islet hyperplastic res

213 bition of BCL6 in KLF6-deficient macrophages completely abrogated the attenuation of pro-inflammatory

214 Elimination of APCs completely abrogated the augmented antitumor responses i

215 surface expression of Notch1 and Notch2, it completely abrogated the binding of Notch receptors with

216 t, since treatment with antilymphocyte serum completely abrogated the CCL18-induced changes.

217 and specific inhibitor of NF-kappaB, nearly completely abrogated the chemokine response to Pneumocys

218 JAK3 mutations, whereas absence of IL2Rgamma completely abrogated the clonogenic potential of JAK3(A5

219 Neutralizing anti-OX40L Abs completely abrogated the CT-induced Th2 cytokine respons

220 vations that a calcineurin inhibitor, FK506, completely abrogated the dephosphorylation, and morphine

221 In contrast, SVL9 tolerization completely abrogated the development of OAD.

222 he lymphocytic choriomeningitis virus (LCMV) completely abrogated the diabetic process.

223 mains necessary for potent N-MLV restriction completely abrogated the disappearance of particulate N-

224 ion of mice prior to injection of MB49 cells completely abrogated the effect of Crry down-regulation

225 SPM in SPM/POPC (1:1) vesicles mitigated and completely abrogated the effect of SPM on the transbilay

226 However, chemical inhibitors of JAK completely abrogated the effects of IFN-alpha-2a on FasL

227 peptide (10 microM) in the pipette solution completely abrogated the effects of ISO on BK channel ac

228 e importantly, elimination of CD8(+) T cells completely abrogated the effects of radiation therapy.

229 We found that DC depletion completely abrogated the elevated levels of many inflamm

230 Moreover, IL-27 treatment completely abrogated the encephalitogenicity of Th9 cell

231 of a small interfering RNA (siRNA) to hsp70 completely abrogated the endogenous levels of hsp70 and

232 rogen response, whereas deletion of the site completely abrogated the estrogen effect.

233 While none of the mutated residues completely abrogated the function of Fur, we were able t

234 ssing-self" or "induced-self." Lack of Bcl10 completely abrogated the generation of GM-CSF and chemok

235 of TCF-1, we found that loss of both factors completely abrogated the generation of KLR G1(lo)IL-7Ral

236 n of CpG-C in liposomes stable above pH 5.75 completely abrogated the IFN-alpha response while increa

237 Knocking down hepatic ATGL completely abrogated the increase in serum insulin follo

238 cells with paraformaldehyde before coculture completely abrogated the induction of NF-kappaB subunits

239 se a neutralizing Ab against TGF-beta, 1D11, completely abrogated the induction of T(reg) cells.

240 more, blocking protein kinase A (PKA) by H89 completely abrogated the inductive effects of tumor-cond

241 Mir-17-5p also completely abrogated the insulin-like growth factor 1-me

242 paran sulfate proteoglycans using heparinase completely abrogated the mechanical induction of MMP act

243 Deletion of seeI, seeL, and seeM completely abrogated the mitogenic activity and synthesi

244 gulatory T cells during the priming response completely abrogated the positive effect of immunologica

245 fected cells, and deletion of the PRE nearly completely abrogated the progesterone effect.

246 Furthermore, distinct PI3-kinase inhibitors completely abrogated the protective effect of Hsp27 expr

247 sitization or after triggering of arthritis, completely abrogated the protective effect of IFN-alpha.

248 ially, but in combination with indomethacin, completely abrogated the protective effects of fluid flo

249 ing nor mutual Jade-1-HBO1 stabilization but completely abrogated the synergistic Jade-1/1L- and HBO1

250 pe mice, the absence of p21(Cip1) expression completely abrogated the TCDD inhibition, and accelerate

251 and 3 reduces activity on undamaged DNA and completely abrogates the ability of the enzyme to bypass

252 ls and shown that inhibition of SGK activity completely abrogates the antiapoptotic effect of GM-CSF.

253 platelets) accelerates factor V activation, completely abrogates the anticoagulant function of tissu

254 phosphoethanolamine methyltransferase enzyme completely abrogates the biosynthesis of phosphatidylcho

255 Sles1 completely abrogates the development of activated T and

256 ression, and inhibition of heme biosynthesis completely abrogates the down-regulation of FGF21 in res

257 hat CTLA-4 on normal effector CD4(+) T cells completely abrogates the dramatically increased expansio

258 a point mutation that inhibits CtBP binding completely abrogates the effects of AME on differentiati

259 Inhibition of this metabolic pathway completely abrogates the exosome-mediated increase in mi

260 ration of FC from HSC by transwell membranes completely abrogates the FC effect on HSC.

261 th the process (eg, integrin, MMP, PKC, Src) completely abrogates the formation of vascular guidance

262 kinase expression in transformed HeLa cells completely abrogates the high concentration of phosphoch

263 A mutation of this site almost completely abrogates the promoter activity.

264 Furthermore, SGTA expression completely abrogates the regulation of receptor function

265 variant of CD11b suggest that this mutation completely abrogates the regulatory effect of CD11b on B

266 with all inhibitors examined, whereas almost completely abrogating the enhancing effects of enoxapari

267 cn K508R mutant transgene partially, but not completely, abrogated the phenotype.

268 ependent TGF-beta signaling greatly, but not completely, abrogates the effect of TGF-beta on Th17 cel

269 irway epithelia, and MUC1-ED immunodepletion completely abrogated their inhibitory activity.

270 lin-reactive T cells with TGF-beta plus IL-6 completely abrogated their pathogenic function despite u

271 and raising animals under axenic conditions completely abrogates their abnormal phenotype, even upon

272 of CD8(+) T cells one day before vaccination completely abrogated therapeutic efficacy, whereas deple

273 AHR knockdown by siRNA completely abrogated this effect.

274 Competitive inhibition with soluble elastin completely abrogated this increase.

275 of Id2 because point mutations at this site completely abrogated this response.

276 erator-activated receptor (PPAR)gamma almost completely abrogates this effect.

277 inant interfering mutant of Rac1 (Rac1(N17)) completely abrogates this effect.

278 of Wnt signalling after re-epithelialization completely abrogates this wounding-induced folliculogene

279 n of allogeneic Tregs substantially, but not completely, abrogated this form of tolerance.

280 mportantly, deletion of SK1 in p53 null mice completely abrogated thymic lymphomas in these mice and

281 Overexpression of TLR10 completely abrogated TLR2-induced interleukin 8 secretio

282 Targeted knockdown of caveolin-1 completely abrogated TNF-alpha-induced RhoA activation,

283 Consistently DRB and dominant-negative CDK9 completely abrogated TNF-alpha-stimulated human MMP-9 pr

284 sympathectomy prevented HSC mobilization and completely abrogated tolerance induction.

285 Selective inhibition of this Treg cell wave completely abrogated tolerance.

286 production of TNF-alpha, IL-6, and IL-10 and completely abrogates transcription of IFN-beta in Bb-sti

287 N-acetyl-cysteine inhibited angiogenesis and completely abrogated transgenic RacCA tumor formation, i

288 eletion of ICOS, CD28, and SAP, partially or completely abrogated tumor development, confirming a T(F

289 GD3S knockdown completely abrogated tumor formation in vivo.

290 ery depot consisting of intratumor hydrogels completely abrogated tumor growth.

291 Pharmacological MEK inhibition completely abrogated tumour growth in BRAF mutant xenogr

292 complementary sites, and repression was not completely abrogated until all three sites were mutated

293 ted up-regulation of Mmp13 transcription was completely abrogated upon removal of the -10 kb enhancer

294 umanized monoclonal antibody (mAb hu2c) that completely abrogates viral cell-to-cell spread, a key me

295 ation signal mutant, whose nuclear import is completely abrogated, we demonstrate that its apoptotic

296 malignant phenotypes but that the effect is completely abrogated when accompanied by an increase in

297 on induced by Brucella-activated T cells was completely abrogated when these cells were cultured with

298 ansion of SEB-reactive Vbeta8(+) T cells was completely abrogated while SEB-nonreactive Vbeta2(+) T c

299 ficiency of both RIPK3 and caspase-8 or FADD completely abrogated Yersinia-induced cell death and cas

300 nd amino terminal to the B-ZIP basic region, completely abrogates Zta capacity to initiate lytic cycl