ライフサイエンスコーパス: complex formation

1 copper in the presence of ammonia to promote complex formation.

2 g to the RecA homology search before ternary complex formation.

3 nding to FSN-1 and RAE-1 reduces FSN-1.RAE-1 complex formation.

4 annel and its structure is unaffected by the complex formation.

5 fic complex is independent of the history of complex formation.

6 n inactivation and inhibition of cofilin/p53 complex formation.

7 ligands and exert specificities in Scribble complex formation.

8 ification including cisplatination, inhibits complex formation.

9 homologous recombination and/or synaptonemal complex formation.

10 iously uncharacterized features of Cas9-gRNA complex formation.

11 sihBVR blocked complex formation.

12 zation of DELLAs to ensure correct ATS-DELLA complex formation.

13 atin modifications to promote pre-initiation complex formation.

14 dels proposed in H-NS-mediated nucleoprotein complex formation.

15 and decreased EGFR/Grb2/Shp2/Gab1 signaling complex formation.

16 tion of Syn5 in early mitosis disrupts SNARE complex formation.

17 structure and underscore key interactions in complex formation.

18 he promoter and the productive transcription complex formation.

19 y mediate distinct assembly steps during 60S complex formation.

20 nteracts with the TSC1 C terminus to mediate complex formation.

21 element, consequently facilitating the open complex formation.

22 guide RNA:target DNA heteroduplex on ternary complex formation.

23 ediates binding through the hydrogen bond in complex formation.

24 sociations, subcellular localization, and co-complex formation.

25 ll permeability, and inhibition of RAB25:FIP complex formation.

26 tic activity of FKBP65 or LH2 did not affect complex formation.

27 ft adopts a "locked" conformation on ternary complex formation.

28 firm a central role for QIL1 in stable MICOS complex formation.

29 cogene dephosphorylated ERK, and negated the complex formation.

30 ciated membrane protein 2), leading to SNARE complex formation.

31 identity of residues that are important for complex formation.

32 the MEKK3 interaction without affecting CCM complex formation.

33 synaptobrevin-2/VAMP2 interaction and SNARE complex formation.

34 alleles) points to individual variations in complex formation.

35 etely disrupt PRL-2.human Cyclin M 3 (CNNM3) complex formation.

36 brB and rrnB1 promoters and facilitates open complex formation.

37 eins provides strong statistical evidence of complex formation.

38 -bisphosphate (PIP2) and is related to SNARE complex formation.

39 -second-order kinetics was found for LA-OVAn complex formation.

40 ts, if this precedes the stage of initiation complex formation.

41 istinct roles in substrate translocation and complex formation.

42 heir fusion competency with respect to SNARE complex formation.

43 Knockdown of Sig-1Rs attenuates the complex formation.

44 iciency or fluorescence intensity during PRE complex formation.

45 for affinity and specificity of the RGG-RNA complex formation.

46 to undergo Fab-arm exchange and limit immune complex formation.

47 partly by disrupting contacts essential for complex formation.

48 cytoplasmic membranes for viral replication complex formation.

49 protein (CBP), to facilitate transcriptional complex formation.

50 ore efficient in promoting membrane-mediated complex formation.

51 the regions in PBP A1 and PgdA required for complex formation.

52 ug delivery, antibody production and protein complex formation.

53 binding at the 5' SS by promoting long-lived complex formation.

54 further show compaction of the protein upon complex formation.

55 s positive and greater than Keq for divalent complex formation.

56 investigation of influenza virus polymerase complex formation.

57 anism that is mediated by ternary AcrAB-TolC complex formation.

58 ins and are thought to instead promote SNARE complex formation.

59 he function of weakly active enzymes through complex formation.

60 omponents of the U2 snRNP and required for A complex formation.

61 biting E3 ligase activity by impairing E2-E3 complex formation.

62 f Bdp1 in TFIIIB assembly and pre-initiation complex formation.

63 ibition phenomena given the enzyme-substrate complex formation.

64 embrane lipids [21, 22] and scaffold protein complex formation [23].

65 es downstream from the site of preinitiation complex formation, a process that involves the transloca

66 beta1 localization, complex formation, activation state, and signaling were

67 e selectivity of dicationic compounds in the complex formation allows for the discrimination of overl

68 Complex formation also induces a tight bend in the DNA a

69 To characterize complex formation among human pancreatic protease zymoge

70 We conclude that complex formation among human pancreatic protease zymoge

71 ese defects were due to deficiencies in mTOR complex formation and activation.

72 ound the interface destabilized higher-order complex formation and altered the cooperative DNA-bindin

73 C-terminus affects multiple aspects of NHE3 complex formation and changes the NHE3 lipid raft distri

74 ion of molecules involved in SNAIL repressor complex formation and demonstrated that HIV enhances exp

75 und, define the biochemical requirements for complex formation and describe the protein-protein inter

76 the herringbone reconstruction, mobile Au-CO complex formation and diffusion, and Au adatom cluster f

77 ve interactions, which restrict illegitimate complex formation and direct limiting helicase-activatio

78 lution with the complexities of higher-order complex formation and directional control representing s

79 irectly to Tcf1 to inhibit beta-catenin/Tcf1 complex formation and does so independently of the Grouc

80 n activate vesicular synaptobrevin for SNARE complex formation and enhance exocytosis in neuroendocri

81 tulated in vitro, impair STAT3-ERBIN-SMAD2/3 complex formation and fail to constrain nuclear pSMAD2/3

82 31, a two-pass transmembrane protein, in MKS complex formation and function.

83 omplexes provided critical insights into tip complex formation and function.

84 and cell-based methods to assess Galpha-RGS complex formation and Galpha enzymatic activity, we foun

85 hich OGT modifies HIRA to regulate HIRA-H3.3 complex formation and H3.3 nucleosome assembly and revea

86 medOB1 is required for telomeric DNA-protein complex formation and it associates with the telomere TT

87 ed in relation to its participation in SNARE complex formation and its interaction with phosphoinosit

88 on of platelets increased platelet-leukocyte complex formation and leukocyte activation, which was ac

89 pproach based on cyclodextrin/drug inclusion complex formation and loading into liposomes was applied

90 ylation, thereby enhancing LEF1-beta-catenin complex formation and long-range chromatin looping at th

91 s in the interface required for higher-order complex formation and long-term plasmid maintenance.

92 corresponding decrease in platelet-leukocyte complex formation and markedly reduced generation of fac

93 unctional theory calculations point to Au-CO complex formation and migration.

94 hat resulted in reduced CARMA1/Bcl-10/MALT-1 complex formation and NF-kappaB-dependent cell survival.

95 this reaction is two-fold: it enables "ate" complex formation and overcomes catalytic inhibition by

96 anisms including folding, chaperone binding, complex formation and phosphorylation.

97 th ion mobility separation (IMS) can analyze complex formation and provide conformation information w

98 ontribute directly to specificity in protein complex formation and provides guidelines for peptidomim

99 onserved, and has important consequences for complex formation and regulation of protein abundance.

100 plied to the isolated DHO subunit mimics the complex formation and reversibly activates the isolated

101 This effect is strictly dependent on complex formation and sorting determinants that regulate

102 ng from MeOH is critical for the hyponitrite complex formation and stabilization.

103 Depletion of ANXA6 in CAFs impaired complex formation and subsequently impaired PDA and meta

104 protein, which was attributed to Cables1/p21 complex formation and supported by their co-localization

105 resulting in attenuation of the Smad3-Smad4 complex formation and suppression of DNA-binding ability

106 AP3 complex formation and the degranulation defect in patien

107 VASP-VASP complex formation and the interaction of VASP with vincu

108 NBS1 from TRF2, promoting TRF2-Apollo/SNM1B complex formation and the protection of leading-strand t

109 tween Drosophila E2F1 and Sd disrupts Yki/Sd complex formation and thereby suppresses Yki target gene

110 xhibited positive cooperativities of ternary complex formation and were more potent degraders than te

111 he possibility that coordination facilitates complex formation and/or function.

112 the binding regions necessary for RBP-J.RITA complex formation, and determine the X-ray structure of

113 U2 snRNP recruitment, enhances spliceosome A complex formation, and facilitates exon definition throu

114 of protein metabolism, regulation of protein complex formation, and protein folding, perhaps associat

115 strate interactions, enzyme-substrate active complex formation, and protein folding-binding interacti

116 gnaling and secretion, inhibited SNAP23/STX4 complex formation, and switched the degranulation patter

117 on of conformational entropy change upon the complex formation, and water molecules structured in the

118 otifs in both Yae1 and Lto1 facilitate their complex formation, and Yae1 recruits Rli1.

119 modelling studies confirmed that 1:1 and 1:2 complex formation are desirable; 1:1 complex formation w

120 metry to address the importance of DnaB-DnaC complex formation as a prerequisite for helicase loading

121 l for HPV infection and CD63-syntenin-1-ALIX complex formation as a prerequisite for intracellular tr

122 these mutated Abs to inhibit membrane attack complex formation as tested in a hemolysis assay.

123 1 and eIF1A promote efficient 48S initiation complex formation at AUG828, which is reduced approximat

124 s reveals that PRPF8 depletion decreases RNP complex formation at most splice sites in exon-intron ju

125 rupted myocardin/SRF and Notch transcription complex formation at respective CArG and CSL binding ele

126 d1 ligand- and Notch1-enhanced myocardin/SRF complex formation at the promoter CArG element.

127 The difference in inclusion complex formation behavior of 1Cl3 with the two macrocyc

128 ecognition was evaluated with the well-known complex formation between avidin and biotin as a model s

129 In vitro, ERdj4 is required for complex formation between BiP and IRE1(LD).

130 ntrol over the geometry and stoichiometry of complex formation between CD19- or CD22-expressing cance

131 tive form of the cytokinetic RhoGEF involves complex formation between ECT-2, centralspindlin and Rho

132 metric, kinetic and thermodynamic aspects of complex formation between heat-induced aggregates of ova

133 The complex formation between luteolin (L) and vanadium(IV)

134 ng experiments showing significantly reduced complex formation between m06 and beta2-microglobulin-as

135 namic model also predicts the free energy of complex formation between macromolecules, which corrobor

136 In human end-stage HF, the complex formation between NDPK-C and Galphai2 was increa

137 This agglomeration is shown to be induced by complex formation between Pb(2+) and citrate groups loca

138 ry (MS) is often used to monitor noncovalent complex formation between peptides and ligands.

139 alphaFXIIa remains bound to polyP70 Indeed, complex formation between polyP70 and alphaFXIIa provide

140 or the influence of phospholipid bilayers on complex formation between rabbit P450 2B4 (CYP2B4) and r

141 presence of excess ribose also destabilized complex formation between RbsB and RbsC.

142 Fusion involves complex formation between SNARE proteins anchored to adj

143 bserved for the TAP1/TAP2 interaction or the complex formation between TPN and MHC I.

144 minal AAA(+) domain of ChlD is essential for complex formation, but some stability is preserved in th

145 ruthenium center, but instead with precursor complex formation by hydrogen bonding.

146 tion fluorescence microscopy, we demonstrate complex formation by showing that bait and prey molecule

147 suggested molecular damage and amylose-lipid complex formation by the linear B-chains of amylopectin,

148 stimulation is an enhancement of DMC1-ssDNA complex formation by the stimulatory BRC repeats.

149 C3a and C5a) and soluble terminal complement complex formation (C5b-9) locally and active TGF-beta1 s

150 This complex formation can modulate their folding, activity a

151 as it enables improved composite polyprotein complex formation compared to traditional trans-compleme

152 correlation with the metal-ligand (citrate) complex formation constant (Kf).

153 The calculation of the complex formation constants in the polymeric membrane wi

154 DNaseI footprinting reveals that this complex formation corresponds to XdhR binding the xdhR g

155 orated by the finding of increased eIF4F-cap complex formation detected after irradiation in all GSC

156 Complex formation differentially influences the stabilit

157 rmodynamics and kinetics to model Cas9:crRNA complex formation, diffusion, site selection, reversible

158 bacterial sporulation and inhibits the open complex formation due to steric clash with sigma region

159 e controls syntaxin-1A engagement into SNARE complex formation during priming.

160 esistant form of GNU, which promotes PNG-GNU complex formation, elevation of Cyclin B, and meiotic de

161 KCNQ-SMIT complex formation facilitates ion channel-solute transpo

162 A peptide inhibitor of SNARE complex formation failed to block exocytosis from either

163 gamma receptor and the requirement of immune complex formation for effector cell activations.

164 erals (DMs) can lead to insoluble lipid-soap complex formation, hampering carotenoid bioaccessibility

165 RNA movement through the ribosome during PRE complex formation has been extensively studied, comparat

166 ubule antigen-specific antibodies and immune complex formation has not been well characterized in hum

167 , EMRE could paradoxically inhibit uniporter complex formation if expressed in excess.

168 on fork showed that RPA promotes DNA-(H3-H4) complex formation immediately adjacent to double-strande

169 in-AMPA receptor complex in vivo and whether complex formation impacts OPC migration in the brain.

170 the driving force for Sf6TSP-polysaccharide complex formation in an overall weak-affinity interactio

171 d junctional tension to inhibit premature TJ complex formation in lower layers while promoting increa

172 e the importance of studying protein-protein complex formation in membrane mimetic systems.

173 beta proteins, confirming NLRP3 inflammasome complex formation in podocytes of Tg26 mice.

174 support the hypothesis of upregulated SNARE complex formation in schizophrenia OFC, possibly favored

175 SI-MS to investigate the factors that govern complex formation in solution and gas phases by comparin

176 is uncertainty regarding the mechanism(s) of complex formation in solution and the extent to which th

177 demonstrate the importance of heterogeneous complex formation in tau function.

178 erestingly, DHX29 impedes the 48S initiation complex formation in the absence of eIF1A perhaps due to

179 platelet activation, and platelet-leukocyte complex formation in the bronchoalveolar space.

180 ZT treatment demonstrate augmented MRP4-CFTR complex formation in the colon, which defines a novel pa

181 induced by Munc13-1 initiates ternary SNARE complex formation in the neuronal system.

182 epends upon localized RNA processing protein complex formation in the nucleus.

183 This interaction is essential for SNARE complex formation in vitro and synaptic vesicle priming

184 s and the individual CDs confirmed inclusion complex formation in water.

185 ws the calculation of the kinetics of immune complexes' formation in a continuous-flow system using c

186 y FH and did not inhibit terminal complement complex formation induced by zymosan.

187 An overview of all of the reported PA-PB1 complex formation inhibitors is provided, and approaches

188 Signal complex formation involves Frizzled4 (Fz4), low-density

189 d PTX2 circulate as a complex in plasma, and complex formation involves the FX activation peptide.

190 and fibrinogen (Fg) and amyloid beta (Abeta) complex formation is a hallmark of Alzheimer's disease.

191 asmodium bromodomain protein PfBDP1 and that complex formation is associated with transcriptional reg

192 We find that DinJ-YafQ complex formation is critically dependent on the last te

193 enzymatic activity and that the ACBD3:PI4KB complex formation is essential for proper function of th

194 ransfer measurements, we show that FtsY-SecY complex formation is guanosine triphosphate independent

195 Our results demonstrate that eIF4F complex formation is not required but eIF4G plays a crit

196 neurotransmitter release and complete SNARE complex formation is required for vesicle fusion and pri

197 Furthermore, we show that SNARE complex formation is required for vesicle fusion, wherea

198 Our findings reveal that BRAF-CRAF complex formation is significantly associated with BRAFi

199 h both factors present, the kinetics of open complex formation is significantly faster than in the pr

200 ed for vesicle fusion, whereas partial SNARE complex formation is sufficient for vesicle docking and

201 le fusion and priming, whereas partial SNARE complex formation is sufficient for vesicle docking and

202 The main contribution to the p38gamma.PTPN4 complex formation is the tight interaction between the C

203 obility, thereby strengthening and weakening complex formation, is described.

204 swelling occurred as a result of host-guest complex formation leading to charge repulsion between th

205 Complex formation leads to a significant reduction in lo

206 f interactions (e.g., electrophilic pi-allyl complex formation, Lewis acid activation, allenylidene c

207 n of i-tRNA in the first round of initiation complex formation licenses the final steps of ribosome m

208 he narrowed binding cleft adds a barrier for complex formation likely influencing the binding kinetic

209 ld-up of negative charge during Meisenheimer complex formation, limiting the scope of SNAr reactions:

210 s-1, a close structural homolog of PU.1, 2:1 complex formation may represent an alternative autoinhib

211 hand, promotes Dcp2 activation via decapping complex formation mediated by the decapping enhancer Hed

212 ide of syntaxin 1a, thereby inhibiting SNARE complex formation, Munc18b and -c, which have a more wid

213 bstrate interaction, enzyme-substrate active complex formation, nascent product formation, and produc

214 SB or RNase HI protein variants that disrupt complex formation nullify this effect.

215 nto the surrounding micelle in solution, and complex formation occurs independently of the ESI proces

216 study, a modified aqueous leaching method by complex formation of amylose with glycerol was employed

217 The inclusion complex formation of both types of alpha-CD powders was

218 Complex formation of HPV16 L2 with OBSL1 was demonstrate

219 Genetic disruption of the complex formation of PRC1 facilitates the targeting of C

220 his article, we provide evidence that immune complex formation of serum IgA plays an important role i

221 ich otherwise facilitates the ligand-induced complex formation of the immune receptor kinases EF-TU R

222 to bacteria, which enhances membrane attack complex formation on M. catarrhalis and thus leads to in

223 recognition sequence and promotes repression complex formation on mRNAs that are not stably bound by

224 structural reorganization likely accompanies complex formation on the head-to-tail array of binding s

225 Pharmacologic inhibition of either TCR-CXCR4 complex formation or PREX1-Rac1 signaling in primary hum

226 P1, that exhibit altered exchange rates upon complex formation or ssDNA binding.

227 tion to goethite at pH 3, suggesting ternary complex formation or, in the case of humic acid, incorpo

228 rmation, Lewis acid activation, allenylidene complex formation, photoredox activation, C-H activation

229 The hetero-molecular complex formation prevents IAPP from self-association an

230 ite sides of the protein allowing multimeric complex formation previously shown in ASC PYD fibril ass

231 Functionally, disrupting DISC1/Ndel1 complex formation prolongs mitotic length and interferes

232 that exhibit significant signal changes with complex formation-properties that may be readily encount

233 ins was conserved but that ribonucleoprotein complex formation required higher PCBP2 and 3CD(pro) con

234 led that as with canonical Type I IRESs, 48S complex formation requires eukaryotic initiation factors

235 Complex formation requires the N-terminal domain of Hook

236 doA in the cytoplasm and prevents MondoA-Mlx complex formation, restricting MondoA's nuclear entry an

237 e showed that a PRL inhibitor could abrogate complex formation, resulting in a decrease in proliferat

238 Complex formation stabilizes the inhibitory activation p

239 , only homotypic interactions participate in complex formation, suggesting that subtle factors differ

240 h based on stochastic simulations of protein complex formation that integrates multi-source data--suc

241 hese studies revealed a dynamic mechanism of complex formation that involves large conformational cha

242 e first or second PHD finger allow for Rpd3S complex formation, the assembled complexes from these mu

243 Upon the inclusion complex formation, the microenvironment of dansyl was mo

244 es conducted on the relevance of Tom70.Hsp90 complex formation, there is a dearth of information rega

245 HX enhances Sirt1 and Sirt1/Cdk2 complex formation through HIF1alpha activation.

246 that Munc18c, like Munc18a, slows down SNARE complex formation through high-affinity binding to synta

247 at Daam2 promotes Wnt signaling and receptor complex formation through PIP5K-PIP2.

248 o CyRPA blocks binding of CyRPA to PfRh5 and complex formation thus illuminating the molecular mechan

249 ion during early steps of Cas9/guide RNA-DNA complex formation, thus additionally destabilizing the p

250 III competes with TbetaRI/TbetaRII signaling complex formation, thus inhibiting TGF-beta-mediated Sma

251 ine capable to disrupt gp130/IL11R signaling complex formation, thus serving as a high-affinity speci

252 es binding to Mis18alpha:Mis18beta, limiting complex formation to the G1 phase of the cell cycle.

253 xorubicin (DOX) prodrug 2 via hetero-ternary complex formation to yield 7.

254 To explore complex formation under physiological conditions, we gen

255 nt manner and positively regulated FLS2-BAK1 complex formation upon MAMP treatment.

256 as theoretical evidence that suggests Au-CO complex formation upon the exposure of CO to active site

257 s and the viral RNA in tombusvirus replicase complex formation using in vitro, yeast-based, and plant

258 The peptides involved in complex formation varied in terms of their size and dive

259 horylation probably promotes the replication complex formation via increasing NS5A interaction with t

260 Complex formation was analyzed through monitoring of the

261 and 1:2 complex formation are desirable; 1:1 complex formation was chosen to have higher weight loadi

262 The functional effect of complex formation was delayed procarboxypeptidase activa

263 This complex formation was driven by increasing entropy.

264 At pH 7.4, CA-BSA complex formation was entropically driven.

265 stically, we show that IL-1-induced RelB/p50 complex formation was further promoted by oncostatin M a

266 The TBA-thrombin complex formation was monitored by differential pulse vo

267 level, V-type amylose-ferulic acid inclusion complex formation was not observed by both co-precipitat

268 Further evidence for gH/UL116 complex formation was obtained by coimmunoprecipitation

269 provide insight into FtsZ-regulator protein complex formation, we determined structures of Escherich

270 Mechanisms for ternary complex formation were characterized by Fourier transfor

271 ropose a potential mechanism for this lectin complex formation where coevolving polar residues of hig

272 plasma membrane, indicating increased SNARE complex formation, whereas FRET with other tested SNAREs

273 n, depletion of USP36 increases TrkA.Nedd4-2 complex formation, whereas USP36 expression disrupts the

274 cts as an acceptor center in charge transfer complex formation which is supported by ESP and contour

275 They facilitate cotranslational protein complex formation, which establishes a role for 3'-UTRs

276 he trajectories reveals on-pathway encounter complex formation, which is driven by electrostatic inte

277 by disruption of cadherin/beta-catenin/actin complex formation, which plays a crucial role in connect

278 cifically of splicing factors required for A complex formation, which relocalize together with SUMO1

279 assigned to symmetry-breaking donor-acceptor complex formation, which revealed a formally forbidden p

280 he digestibility of starch and amylose-lipid complex formation while having no substantial differenti

281 ors, which considerably delay the Cas9/sgRNA complex formation, while not significantly affecting alr

282 rous hydrophobic contacts account for stable complex formation with a buried surface area of 3094 A(2

283 neutralized during its biosynthesis through complex formation with an antitoxin, EsaG, which binds t

284 Zinc complex formation with chlorophyll derivatives in spinac

285 Calcium signaling leads to a promotion of complex formation with Cobl-like's cofactor Abp1.

286 LHCPs and cpSRP43 occurred independently of complex formation with cpSRP54 and that the interaction

287 ssive dynein movements that are activated by complex formation with dynactin and a cargo adaptor.

288 plication both via inhibition of DnaB6-DnaC6 complex formation with excess DnaB, as shown here, and p

289 heir pathogenicity by assaying the impact on complex formation with Ggamma and resultant mutant Gbeta

290 gL mutant was not a result of alterations in complex formation with gH or alterations in cellular loc

291 ter being responsible for most of Scribble's complex formation with other proteins.

292 drug pentamidine inhibits calcium-dependent complex formation with p53 ((Ca)S100B.p53) in malignant

293 ine self-administration, BRG1 expression and complex formation with SMAD3 are increased in the nucleu

294 Amylose-lipid complex formation with suitable fatty acids/lipids seems

295 cattering was used to demonstrate that, upon complex formation with target RNA or DNA, TIA-1 RRM23 ad

296 ) shows significant differences in inclusion complex formation with two different macrocyclic hosts,

297 phosphorylation of 53BP1 at S380 accelerates complex formation with USP7 and CENPF to regulate their

298 ity of PARP1 is not required for the initial complex formation with XPC in the nucleoplasm but it enh

299 bations in biochemical signaling and protein complex formation within neurons.

300 we identify one point mutant that abrogates complex formation without affecting protein structure.