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2 The crystal structure of aldose reductase complexed with 13 revealed an interaction pattern explai
3 seen in the crystal structure of THp-(1-43) complexed with 14-3-3gamma, the region surrounding pSer1
5 eening, structures of the stabilized beta1AR complexed with 19 and 20 were determined at resolutions
6 lution, and the structure of Sco GlgEI-V279S complexed with 2,5-dideoxy-3-O-alpha-D-glucopyranosyl-2,
9 Structures of the stabilized mGlu5 receptor complexed with 25 and another molecule in the series, 14
10 atalytically inactive S105A variant of DxnB2 complexed with 3-Cl HOPDA revealed a binding mode in whi
14 ee distinct human TCRs, CA5, SB27, and SB47, complexed with a "super-bulged" viral peptide (LPEPLPQGQ
15 er, the direct co-injection of thrombin, pre-complexed with a biotinylated aptamer bound to streptavi
16 livery of plasmid DNA encoding the CFTR gene complexed with a cationic liposome is a potential treatm
18 gically active recombinant trimeric SP-D CRD complexed with a delipidated Eagan 4A LPS suggests that
19 ical to that seen previously for alpha5beta1 complexed with a Fab that allosterically inhibits ligand
20 ammonium chloride (PDDA) polyelectrolyte was complexed with a fluorosurfactant layer (FL), which prov
21 s are 'DASHed' with recombinant Cas9 protein complexed with a library of guide RNAs targeting unwante
22 ation dendrimers of siRNA can be effectively complexed with a low-molecular-weight, cationic polymer
23 yers containing hydroxyapatite nanoparticles complexed with a natural polymer chitosan create an oste
24 omic resolution structure of CVA6 A-particle complexed with a neutralizing antibody maps an immune-do
26 irus (HIV) type 1 reverse transcriptase (RT) complexed with a non-polypurine tract RNA/DNA hybrid has
27 resolution x-ray crystal structures of EF-G complexed with a nonhydrolyzable guanosine 5'-triphospha
30 se domain of human CK1delta, one apo and two complexed with a potent and selective CK1delta/epsilon i
32 protein from Streptococcus pyogenes was pre-complexed with a single guide RNA targeting downstream o
34 inally, the co-crystal structure of TYK2 JH2 complexed with a small molecule inhibitor demonstrates t
36 port the crystal structures of DepH and DepH complexed with a substrate analogue S,S'-dimethyl FK228
37 lution crystal structure of zebrafish HDAC10 complexed with a transition-state analogue inhibitor rev
38 , we determined the crystal structure of APN complexed with a tumor-homing peptide containing a repre
39 In the presence of A20, coralyne molecules complexed with A20 through A2-coralyne-A2 coordination.
40 Met-expressing oncolytic Ad (oAd; RdB/shMet) complexed with ABP-PEG-HCBP1 delivered oAd efficiently i
44 PM1 was affinity-purified from Sf9 cells and complexed with amphipol, followed by detergent removal.
45 tures of wild-type HIV-1 and HIV-2 proteases complexed with amprenavir and darunavir to models of the
47 51-TI8, to our knowledge the first human TCR complexed with an 8-mer peptide, explained this bias, as
48 al structure of the S1191L mutant of FH19-20 complexed with an activation-specific complement fragmen
49 ucture of the deuterated Ca(2+)-CIB1 protein complexed with an alphaIIb peptide was first determined
50 e extracellular interacting region of Notch1 complexed with an engineered, high-affinity variant of J
51 the phorbol-binding domain (C1B) of PKCdelta complexed with an ether (methoxymethylcycloprane) and wi
53 e bacteria is a potent platelet agonist when complexed with anti-PGN antibody and could contribute to
54 ructures of chikungunya virus-like particles complexed with antibody fragments (Fab) of two highly pr
55 y employing 23-29 nucleotide (nt) small RNAs complexed with argonaute proteins to suppress parasitic
61 ups of azaBODIPYs were oxidized with DDQ and complexed with BF3.Et2O to obtain covalently linked azaB
62 ons between cryo-EM structures of Env trimer complexed with BG1 (6.2 A resolution) and PG9 (11.5 A re
63 y of supercharged Cre protein and Cas9:sgRNA complexed with bioreducible lipids into cultured human c
64 ectron microscopy (cryoEM) structures of HD5 complexed with both neutralization-sensitive and -resist
65 l structures of Platypodium elegans lectin A complexed with branched trimannose and symmetrical compl
68 de) with tetrathiafulvalene (TTF) end groups complexed with CBPQT(4+) induced positive thermoresponsi
71 long with crystal structures of these agents complexed with CDK2 to highlight differences in their bi
72 and the MIF4G domain of the splicing factor Complexed With Cef1 (CWC22), an essential prerequisite f
73 We solved the crystal structures of EXLX1 complexed with cellulose-like oligosaccharides to find t
74 -coding RNAs produced from active arrays are complexed with CENP-A and CENP-C, while inactive-array t
75 We show that mucosal immunization with UV-Ct complexed with charge-switching synthetic adjuvant parti
77 leukemia virus-like particles (M-VLPs) were complexed with chitosan (Chi) or liposomes (Lip) compris
78 ke particles (M-VLPs) were electrostatically complexed with chitosan (chi) to replace the function of
81 anio rerio HDAC6 (henceforth simply "HDAC6") complexed with compounds that selectively inhibit HDAC6
82 lenimine (PEI) and made comparisons with PEI complexed with conventional plasmid DNA (encoding BMP-2)
83 Doxorubicin fluorescence was reduced when complexed with copper, and nuclear fluorescence was redu
84 as a series of dithiocarbamates, which, when complexed with copper, induced reactive oxygen species-d
85 nic micelle (CM) or anionic micelle (AM) was complexed with counter-charged proteins leading to nanos
86 acrylamide) (PNTs) has been synthesized and complexed with Cu(2+) in order to serve as models for in
87 ns containing electron-donating substituents complexed with cucurbit[8]uril (CB[8]) in a 1:1 stoichio
91 lus DNA polymerase I large fragment variants complexed with deoxy-, ribo-, and dideoxynucleotides and
92 we report four crystal structures of polbeta complexed with dG*dTTP and dA*dCTP mismatches in the pre
94 te analog with E(m) ~-450 mV, but not Eu(II) complexed with diethylene triamine pentaacetic acid (E(m
97 ecular weight linear polyethylenimine (LPEI) complexed with DNA and surrounded by a shell of polyethy
99 epeats (CRISPR)-associated Cas9 endonuclease complexed with dual-RNAs to introduce precise mutations
100 the processive motility of mammalian dynein complexed with dynactin and BicD2 (DDB) on tyrosinated v
102 ess the conformational states of the protein complexed with each of eight unique Nbs that bind exclus
106 cult to evaluate the residual drug, which is complexed with excessive amounts of ADA and endogenous s
108 t FimH adopts an elongated conformation when complexed with FimC, but, when incorporated into the pil
109 stal structures of a mammalian P2X7 receptor complexed with five structurally-unrelated antagonists.
110 Recent X-ray structures of two chemokines complexed with full-length receptors provided unpreceden
111 solved a 3.58 A crystal structure of 8ANC195 complexed with fully glycosylated Env trimer, revealing
113 designed ankyrin repeat proteins (DARPins), complexed with GFP, which revealed different but overlap
114 CSV86 (ppGBP) in unliganded form (2.5 A) and complexed with glucose (1.25 A) and galactose (1.8 A).
115 tion by presenting four human OGA structures complexed with glycopeptide substrates containing a sing
117 utant A1 and A1 containing two VWD mutations complexed with GPIbalpha containing two PT-VWD mutations
118 al can regenerate chromophore-depleted Rho*e complexed with Gt and FAK*TSA peptide containing Lys(296
119 es polysporus Argonaute (KpAGO) fortuitously complexed with guide RNA originating from small-RNA dupl
120 structure of human papillomavirus 16 (HPV16) complexed with H16.U4 fragments of antibody (Fab) was so
121 resolution (1.9 A) crystal structure of m826 complexed with H7N9 HA indicates that m826 binds an epit
124 the tyrosine phosphorylated form, was found complexed with HIF1alpha and active Src, both within the
127 o these peptides only when the peptides were complexed with HLA-A2 (KRAS peptide) or HLA-A3 (EGFR pep
130 ditions of lipids/fatty acids, starch sample complexed with HSO (hydrogenated sunflower oil) (14.1+/-
132 to identify 747 candidate proteins that are complexed with Huntingtin (Htt) in distinct brain region
137 circulate in HCV-infected individuals, LVPs complexed with immunoglobulin were precipitated with pro
138 nology to target the insulin receptor (INSR) complexed with insulin and identified a high affinity, a
140 brary of over 30 peptides, each of which was complexed with IONPs and evaluated for colloidal stabili
141 inactive catalytic nucleophile mutant enzyme complexed with isomaltohexaose, isomaltoheptaose, isomal
143 tures of toluene 4-monooxygenase hydroxylase complexed with its electron transfer ferredoxin and comp
144 tures of the ErbB4/HER4 extracellular region complexed with its ligand Neuregulin-1beta that resolve
145 determined the crystal structure of MHV NTD complexed with its protein receptor murine carcinoembryo
146 ous crystal structures of cytochrome P450cam complexed with its redox partner, putidaredoxin (Pdx), s
147 al structure of oxidized and reduced P450cam complexed with its redox partner, putidaredoxin (Pdx), t
149 o this end, the structure of rabbit P450 4B1 complexed with its substrate octane was determined by X-
150 nit of the endocytosis adaptor protein, AP2, complexed with Kir6.2 predicted that mu2 docks by intera
153 epitope (PADRE)-derivatized-dendrimer (PDD), complexed with liposomal amphotericin B (LAmB) in an L.
155 high-resolution crystal structures of LTA4H complexed with LTA4, providing the structural underpinni
156 ime-resolved spectra of firefly oxyluciferin complexed with luciferase from the Japanese firefly (Luc
157 LYK5 identified PLANT U-BOX13 (PUB13), which complexed with LYK5, but this complex dissociated upon a
158 idues 46-53 of murine H-2L(d) MHC-I H chain, complexed with mAb 64-3-7, demonstrates solvent exposure
161 Furthermore, the structure of reduced PutA complexed with menadione bisulfite reveals the elusive q
162 Protein arginine methyltransferase 5 (PRMT5) complexed with MEP50/WDR77 catalyzes arginine methylatio
163 crystal structures of aristolochene synthase complexed with Mg(2+)3-PPi and ammonium or iminium analo
165 and (19) F NMR studies of the G-protein RhoA complexed with MgF3(-) , GDP, and RhoGAP, which has the
167 EM 3D reconstructions of p150(glued)-CAP-Gly complexed with microtubules revealed the recognition of
168 catalytic core (residues 113-626) tetramers, complexed with mixtures of nucleotides, including dGTP/d
169 n microscopy (EM) structures of bNAb 8ANC195 complexed with monomeric gp120 and trimeric Env, respect
170 the first crystal structure of human ALDH1A3 complexed with NAD(+) and the product all-trans retinoic
171 uctures of horse liver alcohol dehydrogenase complexed with NAD(+) and unreactive substrate analogues
172 precipitation studies revealed that SphK2 is complexed with NCDase and cytochrome oxidase (COX) subun
176 B10 adopts an open-inwards conformation when complexed with nonhydrolysable ATP analogs, in contrast
177 precipitation, BET proteins were found to be complexed with Nrf2, whereas chromatin-immunoprecipitati
178 crystal structure of Aquifex aeolicus DnaB, complexed with nucleotide, reveals a newly discovered co
182 (the etiological agent of meningitis, NmAPN) complexed with organophosphorus compounds were resolved
183 , and we found that in its crystal structure complexed with p25 cyclin a water/hydroxide molecule rem
184 ve determined the crystal structures of HetR complexed with palindromic DNA targets, 21, 23, and 29 b
185 s from macrocyclic chelates (e.g., DOTP(8-)) complexed with paramagnetic thulium (Tm(3+)), to generat
188 n is reported here for Escherichia coli DsbA complexed with PFATCDS, a heptapeptide derived from the
189 of a serotonin 2A receptor (5-HT(2A)R) model complexed with pharmacologically and structurally divers
190 Negatively charged nucleic acids are often complexed with polycationic transfection agents before d
191 ed ribonucleic acid (cmRNA) (encoding BMP-2) complexed with polyethylenimine (PEI) and made compariso
192 examine the effects of miR-124 in vivo when complexed with polyethylenimine-derived nanoparticles.
194 ted to the nanopore, and the conjugates were complexed with primer/template DNA and inserted into lip
195 Overall, spray drying the blueberry extracts complexed with protein proved to be an environment-frien
197 ntibiofilm agents; gallium (Ga) or zinc (Zn) complexed with protoporphyrin IX (PP) or mesoprotoporphy
198 nity for prostate specific antigen (PSA) was complexed with PSA prior to being immobilised on the sur
199 crystal structures of 23 of these compounds complexed with PTR1, and evaluated in screens for enzyme
205 hydrolysis is higher in energy when RhoA is complexed with RhoGAPArg85'Ala relative to wild-type (WT
206 present the 3D structure of HCoV-OC43 N-NTD complexed with ribonucleoside 5'-monophosphates to ident
207 The 1.8 A resolution structure of RIFMO complexed with RIF represents the precatalytic conformat
208 ween P450s 3A4 and 3A5, the structure of 3A5 complexed with ritonavir was determined by X-ray crystal
210 ryanodine receptor 2 (RyR2) in CM T-tubules, complexed with RyR2 in human and rat heart, and specific
211 fragment of mouse viperin (residues 45-362) complexed with S-adenosylhomocysteine (SAH) or 5'-deoxya
212 om SIV that infects sooty mangabeys (SIVsmm) complexed with SAMHD1-DCAF1 identifies molecular determi
215 ection of an MRI-detectable serotonin sensor complexed with serotonin, together with serial imaging a
217 r in their structures were prepared and then complexed with siRNA at different ratios to generate a s
218 X-ray structural characterization of Pol eta complexed with site-specifically platinated DNA at both
220 e of Gla domain of activated Protein C (APC) complexed with soluble endothelial Protein C receptor (s
222 involves circulating hypogalactosylated IgA1 complexed with soluble IgA Fc receptor I (sCD89) and/or
223 cells accelerates autophagy in myotubes when complexed with soluble IL-6 receptor (trans-signaling).
230 structural models of fibrin(ogen) fragment D complexed with synthetic peptides GPRP (knob 'A' mimetic
235 microscopy structures of the immature virus complexed with the 2H2 antigen binding fragments (Fab) a
237 ne of these antibodies, L363, bound to mCD1d complexed with the alphaGalCer analog C20:2, revealing t
238 tructure of LspA from Pseudomonas aeruginosa complexed with the antimicrobial globomycin at 2.8 angst
241 X-ray structure of the enterovirus 71 virion complexed with the capsid-binding inhibitor WIN 51711.
242 anionic PGA-CDDP which was electrostatically complexed with the cationic polymeric metformin (polymet
244 tal structures of CD4-stabilized gp120 cores complexed with the Fab fragments of two nonneutralizing,
245 text of the nucleosome and in H2A/H2B dimers complexed with the histone chaperone, FACT, suggesting t
247 d functional monomers, which are dynamically complexed with the host molecule cucurbit[8]uril (CB[8])
248 and the crystal structure of the minimal E3 complexed with the identified binding fragment of ATG3.
250 Data Bank code 4GQS) of cytochrome P450 2C19 complexed with the inhibitor (2-methyl-1-benzofuran-3-yl
251 he SaEctD crystal structure in its apo-form, complexed with the iron catalyst, and in a form that con
253 ts less strongly expressed isoform AP1M1 are complexed with the large subunit gamma-adaptin of AP-1.
254 ibitors containing novel tridentate chelates complexed with the M(CO)(3) core (M = Re or (99m)Tc) wer
255 Ms) mannan-binding lectin (MBL) and ficolins complexed with the MBL-associated serine proteases (MASP
256 The crystal structure of murine CD3epsilon complexed with the mitogenic anti-CD3epsilon antibody 2C
258 beta binds specifically to IL-1R3 when it is complexed with the newly discovered alternative IL-1 rec
259 ion of the population of each protein is not complexed with the other and that they may accomplish in
260 present a crystal structure of WT p110alpha complexed with the p85alpha inter-SH2 domain and the inh
262 gement compared with that of the P22 homolog complexed with the portal, which is achieved by repositi
263 whose open-channel structure was determined complexed with the positive allosteric modulator ivermec
265 themselves, but instead to proteins that are complexed with the potassium channel, in particular leuc
266 mutants PutA86-630D370N and PutA86-630D370A complexed with the proline analogue l-tetrahydro-2-furoi
267 einococcus radiodurans in the oxidized state complexed with the proline analogue L-tetrahydrofuroic a
270 RecA protein onto gapped DNA (gDNA) that is complexed with the single-stranded DNA-binding protein i
271 dialkoxynaphthalene guest molecules, becomes complexed with the tetra cationic macrocyclic host CBPQT
272 t was active and primarily an activator when complexed with the transcriptional factors RELA, IKZF2 a
273 protein arginine methyltransferase PRMT5 is complexed with the WD repeat protein MEP50 (also known a
276 structures of five different retrovirus INs complexed with their respective viral DNA or branched vi
278 The sensor consists of a gold nanoparticle complexed with three different fluorescent proteins that
279 crystal structure of aristolochene synthase complexed with three Mg(2+) ions and the unreactive subs
280 f the DNA duplex sequence d(CGCGAATTCGCG)(2) complexed with three minor-groove ligands are reported.
281 crystal structures of Aquifex aeolicus SelA complexed with tRNA(Sec) revealed that the ring-shaped d
282 phosphate-dependent processive helicase when complexed with two accessory proteins, eIF4G and eIF4B.
283 tructures of NolR in the unliganded form and complexed with two different 22-base pair (bp) double-st
285 tonated serine octamers and anionic octamers complexed with two halogen ions strongly prefer homochir
286 We also solved the structure of FIPV M(pro) complexed with two inhibitors, delineating the structura
287 ylene glycol) (PEG) tail were non-covalently complexed with two lipids, 1,2-dioleoyl-sn-glycero-3-pho
288 rt two crystal structures of the human TPST1 complexed with two substrate peptides that are catalysed
290 of all four available structures of PDEdelta complexed with various prenylated proteins/peptides show
295 CryoEM maps of neutralizing Fab fragments complexed with VLPs have been interpreted using the crys
296 econstruction of the ZM197M SOSIP.664 trimer complexed with VRC01 Fab against the CD4 binding site at
299 -ray structures of 4a and related inhibitors complexed with yeast proteasomes revealed the structural
300 tal ion chelators bipyridine and terpyridine complexed with Zn(2+) (ZnBip and ZnTerp) act as CCR5 ago
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