1 Although they
comprise a family of 10 genes, NDPK-A and -B are ubiquit
2 Mammalian septins
comprise a family of 13 genes that encode GTP-binding pr
3 Human aldehyde dehydrogenases (ALDHs)
comprise a family of 17 homologous enzymes that metaboli
4 The S100 proteins
comprise a family of 21 low molecular weight (9-13 kDa)
5 uman ATP-binding cassette (ABC) transporters
comprise a family of 48 membrane-spanning transport prot
6 The fibronectins (FN)
comprise a family of adhesive extracellular matrix prote
7 Cathelicidins
comprise a family of antimicrobial peptides sharing a hi
8 Plakophilins (Pkp-1, -2, and -3)
comprise a family of armadillo repeat-containing protein
9 ase I) is ubiquitous in eukaryotic cells and
comprises a family of as many as 14 isoforms (including
10 dduction by lipophilic electrophiles and may
comprise a family of biomarkers for oxidative stress.
11 Cadherins
comprise a family of calcium-dependent cellular adhesion
12 Tropomodulins (Tmods)
comprise a family of capping proteins for actin filament
13 Plant HKT proteins
comprise a family of cation transporters together with p
14 Neutrophil defensins
comprise a family of cationic peptides that possess pote
15 Rse, Ax1, and c-Mer
comprise a family of cell adhesion molecule-related tyro
16 Toll-like receptors
comprise a family of cell surface receptors that play a
17 Signal regulatory proteins (SIRPs)
comprise a family of cell surface signaling receptors di
18 NF-kappaB
comprises a family of cellular transcription factors tha
19 The liposidomycins
comprise a family of complex nucleoside antibiotics that
20 Vitamin B6
comprises a family of compounds that is essential for al
21 alpha-Chemokines
comprise a family of cytokines that are chemotactic for
22 cers and activators of transcription (STATs)
comprise a family of cytoplasmic signaling proteins that
23 Fibroblast growth factors (FGFs)
comprise a family of developmental regulators implicated
24 inflammatory responses and immune function,
comprises a family of dimeric transcription factors that
25 )-homology domain containing proteins (EHDs)
comprise a family of dynamin-related mechano-chemical AT
26 luding 9-HODE, 13-HODE, and 9 and 13-oxoODE,
comprise a family of endogenous TRPV1 agonists.
27 Sirtuins
comprise a family of enzymes found in all organisms, whe
28 Sirtuins
comprise a family of enzymes that catalyze the deacetyla
29 Phosphodiesterases (PDEs)
comprise a family of enzymes that modulate the immune re
30 Polo-like kinases
comprise a family of evolutionarily conserved serine/thr
31 Noelins
comprise a family of extracellular proteins with propose
32 Inhibitors of Activated STAT (PIAS) proteins
comprise a family of five mammalian proteins which have
33 Secreted frizzled-related proteins (sFRPs)
comprise a family of five secreted glycoproteins that an
34 Ovarian tumour deubiquitinases
comprise a family of fourteen human enzymes, many of whi
35 Pneumocystis species
comprise a family of fungi, each of which appears to be
36 Protease-activated receptors (PARs)
comprise a family of G protein-coupled receptors with a
37 Muscarinic acetylcholine receptors
comprise a family of G-protein-coupled receptors that di
38 6 (also termed GADD45alpha, beta, and gamma)
comprise a family of genes that encode for related prote
39 Obscurins
comprise a family of giant (~870- to 600-kDa) and small
40 Platelet-derived growth factors (PDGFs)
comprise a family of growth factors strongly implicated
41 Septins
comprise a family of GTP-binding proteins that oligomeri
42 Dynamins
comprise a family of GTPases that participate in the ear
43 Integrins
comprise a family of heterodimeric extracellular matrix
44 Neuronally coexpressed ELAV/Hu proteins
comprise a family of highly related RNA binding proteins
45 Type I interferon (IFN-alpha/beta)
comprises a family of immunomodulatory cytokines that ar
46 IAPs
comprise a family of inhibitors of apoptosis found in vi
47 The leukocyte Ig-like receptors (LIRs)
comprise a family of inhibitory and activating cell-surf
48 l arrestin, betaarrestin1, and betaarrestin2
comprise a family of intracellular proteins that desensi
49 SWI/SNF
comprises a family of large, multisubunit complexes pres
50 Wnts
comprise a family of lipid-modified, secreted signaling
51 Chemokines
comprise a family of low-molecular-weight proteins that
52 FcR-like (FcRL) proteins
comprise a family of lymphocyte receptors with homology
53 ifically, specialized proresolving mediators
comprise a family of mediators that include arachidonic
54 Na(+)/H(+) antiporters
comprise a family of membrane proteins evolutionarily co
55 Ribonucleases H (RNases H)
comprise a family of metal-dependent enzymes that cataly
56 Here we show that two-pore channels (TPCs)
comprise a family of NAADP receptors, with human TPC1 (a
57 The sirtuins (SIRT 1-7)
comprise a family of NAD(+)-dependent protein-modifying
58 delta-Protocadherins
comprise a family of neural adhesion molecules that are
59 Sialic acids
comprise a family of nine-carbon ketosugars that are ubi
60 Chicken repeat 1 (CR1) elements
comprise a family of non-long terminal repeat (LTR) retr
61 In this study, we show that EIN3 and EILs
comprise a family of novel sequence-specific DNA-binding
62 ARs; PPAR-alpha, PPAR-delta, and PPAR-gamma)
comprise a family of nuclear receptors that sense fatty
63 Retinoid X receptors (RXRs)
comprise a family of nuclear retinoid activated transcri
64 The hypoxia-inducible factors (HIFs)
comprise a family of oxygen-sensitive basic helix-loop-h
65 Oxylipins
comprise a family of oxygenated fatty acid-derived signa
66 Polynucleotide phosphorylases
comprise a family of phosphate dependent 3'-5' RNA exonu
67 Grp1, ARNO, and Cytohesin-1
comprise a family of phosphoinositide-dependent Arf GTPa
68 is-specific serine/threonine kinases (TSSKs)
comprise a family of post-meiotic kinases expressed in s
69 Septins
comprise a family of proteins involved in a variety of c
70 wo reticulocyte binding proteins of P. vivax
comprise a family of proteins involved in host cell sele
71 RGS proteins
comprise a family of proteins named for their ability to
72 Runx transcription factors
comprise a family of proteins that are essential for org
73 The regulators of G protein signaling (RGS)
comprise a family of proteins that attenuate G protein-m
74 MeCP2, MBD1, MBD2, MBD3, and MBD4
comprise a family of proteins that contain a methyl-CpG
75 Annexins
comprise a family of proteins that exhibit a Ca2+-depend
76 ceptor protein tyrosine phosphatases (RPTPs)
comprise a family of proteins that feature intracellular
77 Chemokines
comprise a family of proteins that function in the immun
78 The angiopoietins
comprise a family of proteins that have pro or antiangio
79 The IAPs (inhibitors of apoptosis)
comprise a family of proteins that oppose caspases and t
80 C-type lectins expressed on myeloid cells
comprise a family of proteins that share a common struct
81 Sorting nexins (SNX)
comprise a family of proteins with homology to several y
82 We show here that HAX1
comprises a family of proteins.
83 Protein-C slow (sMyBP-C), encoded by MYBPC1,
comprises a family of regulatory proteins of skeletal mu
84 Protein kinase C (PKC) isozymes
comprise a family of related enzymes.
85 Dengue viruses (DENV)
comprise a family of related positive-strand RNA viruses
86 myocardin, MRTF-A/MKL1/MAL, and MRTF-B/MKL2,
comprise a family of related transcriptional coactivator
87 e enzyme families, and the proteasome itself
comprises a family of related but functionally distinct
88 variety of enzymes present in all phyla and
comprises a family of related molecules containing molyb
89 Protein kinase C (PKC)
comprises a family of related phospholipid-dependent ser
90 e adenosine deaminases acting on RNA (ADARs)
comprise a family of RNA editing enzymes that selectivel
91 Bone morphogenetic proteins
comprise a family of secreted ligands implicated in nume
92 Frizzled related proteins (FRPs)
comprise a family of secreted molecules that contain an
93 Chemokines
comprise a family of secreted proteins that activate G p
94 Wnts
comprise a family of secreted proteins that interact wit
95 Hedgehog (Hh) proteins
comprise a family of secreted signaling molecules essent
96 Wnts
comprise a family of secreted signaling proteins that re
97 Acylfulvenes
comprise a family of semisynthetic natural product deriv
98 n) linked to one or more GlcNAc residues and
comprise a family of serially related structures.
99 Protein kinase Cs (PKCs)
comprise a family of serine-threonine kinases that are m
100 The p90 ribosomal S6 kinases (RSKs)
comprise a family of serine/threonine kinases that lie a
101 Thus, CD34, podocalyxin, and endoglycan
comprise a family of sialomucins sharing both structural
102 FBP, FBP2, and FBP3
comprise a family of single-strand DNA- binding proteins
103 n, hepatitis delta virus, and glmS ribozymes
comprise a family of small catalytic RNA motifs that cat
104 The secreted phospholipases A(2) (sPLA(2)s)
comprise a family of small secreted proteins with the ab
105 Ubiquitin C-terminal hydrolases (UCHs)
comprise a family of small ubiquitin-specific proteases
106 Tumor suppressors p53, p63 and p73
comprise a family of stress-responsive transcription fac
107 Type I signal peptidases (SPs)
comprise a family of structurally related enzymes that c
108 DHP and CRMP proteins
comprise a family of structurally similar proteins that
109 Pbx proteins
comprise a family of TALE (three amino acid loop extensi
110 urotrophic factor (GDNF) and neurturin (NTN)
comprise a family of TGF-beta-related neurotrophic facto
111 CCAAT/enhancer-binding proteins (C/EBPs)
comprise a family of transcription factors that are crit
112 GATA proteins
comprise a family of transcription factors that are requ
113 Transducers and Activators of Transcription)
comprise a family of transcription factors that reside i
114 ctivator protein one (AP1) (jun/fos) factors
comprise a family of transcriptional regulators (c-jun,
115 Early growth response (Egr) proteins
comprise a family of transcriptional regulators (Egr1-4)
116 CD44
comprises a family of transmembrane receptors that can g
117 Synaptogyrins
comprise a family of tyrosine-phosphorylated proteins wi
118 Secretory carrier membrane proteins (SCAMPs)
comprise a family of ubiquitous membrane proteins of tra
119 Protein kinase C (PKC)
comprises a family of ubiquitous enzymes transducing sig
120 ers of the family Enterobacteriaceae (SPATE)
comprise a family of virulence proteins secreted by ente
121 The VEGF ligands
comprise a family of well-studied mitogens/permeability
122 MMPs
comprise a family of zinc endopeptidases that can modify
123 Matrix metalloproteinases (MMPs)
comprise a family of zinc endopeptidases that play major
124 Carbonic anhydrases (CAs)
comprise a family of zinc-containing enzymes that cataly