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1 f obsessive-compulsive disorder (OCD), where compulsive actions are recognized as disproportionate, w
4 calation of alcohol drinking associated with compulsive alcohol drinking in dependent, but not in non
5 al therapeutic strategy for the treatment of compulsive alcohol drinking in humans carrying the Met66
8 essive drinking, for which treatments exist, compulsive alcohol seeking is therefore another key feat
13 d both alcohol seeking and alcohol intake in compulsive and non-compulsive rats, indicating its thera
19 tive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders and to ev
20 tive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders is unclea
21 h as quinine, a paradigm considered to model compulsive aspects of human alcohol use disorders (AUDs)
24 yses revealed a positive correlation between compulsive behavior (measured with the Repetitive Behavi
26 t understanding highlights three elements of compulsive behavior as it applies to pathological overea
29 ptive processes to complementary facets of a compulsive behavior resulting from operant reward learni
35 hypocaloric feeding schedules (HFS) exhibit compulsive behavioral responses involving food anticipat
36 nate hypothalamic response and expression of compulsive behavioral responses involving meal anticipat
37 autistic features, mood disorders, obsessive-compulsive behaviors and hetero- and autoaggression.
38 l as a transdiagnostic impairment underlying compulsive behaviors and representing a promising therap
40 rallels between the emergence of repetitive, compulsive behaviors and the acquisition of automated be
41 ordered quantitative variation in social and compulsive behaviors established linkage to two loci for
43 asure of distress associated with preventing compulsive behaviors significantly correlated with TSPO
44 ined phenotypes included social interaction, compulsive behaviors, aggression, hyperactivity, anxiety
45 gest synaptic adhesion as a key component in compulsive behaviors, and show that targeted sequencing
57 d structural imaging predictors of impulsive-compulsive behaviour (ICB) in de novo Parkinson's diseas
67 e hypothesized that TAAR1 may have a role in compulsive, binge-like eating; we tested this hypothesis
70 een established as efficacious for obsessive-compulsive disorder (OCD) among older children and adole
71 the mean number was 0.9 (1.3) when obsessive-compulsive disorder (OCD) and attention-deficit/hyperact
72 ptomatic of psychopathologies like obsessive-compulsive disorder (OCD) and autism spectrum disorders
73 circuits in the pathophysiology of obsessive-compulsive disorder (OCD) and OC-spectrum disorders.
74 behavioral alterations related to obsessive-compulsive disorder (OCD) and the role of TNFalpha and r
75 een linked with the development of obsessive-compulsive disorder (OCD) and tic disorders, a concept t
76 perseverative behaviors related to obsessive-compulsive disorder (OCD) and Tourette syndrome (TS).
79 icits in goal-directed behavior in obsessive-compulsive disorder (OCD) are caused by impaired frontos
80 tism spectrum disorders (ASDs) and obsessive compulsive disorder (OCD) are often comorbid with the ov
84 Approximately 10% of patients with obsessive-compulsive disorder (OCD) have symptoms that are refract
86 Mode Network (DMN) deactivation in Obsessive Compulsive Disorder (OCD) in the transition between a re
87 even when genomic data are limited.Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder
92 ior therapy (CBT) among youth with obsessive-compulsive disorder (OCD) is effective, but many patient
96 he compulsive behaviour underlying obsessive-compulsive disorder (OCD) may be related to abnormalitie
97 e/chronic tic disorder (TS/CT) and obsessive-compulsive disorder (OCD) overlap in their phenomenologi
98 elatives of these SCZ patients, 13 obsessive-compulsive disorder (OCD) patients, 18 unaffected first-
99 otential, is a reliable finding in obsessive-compulsive disorder (OCD) research and may be an endophe
100 /hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) share impaired inhibitory cont
101 Autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD) share inhibitory control defic
102 in the CSTC pathway is involved in obsessive compulsive disorder (OCD), a neuropsychiatric disorder c
103 tionships among Tourette syndrome, obsessive-compulsive disorder (OCD), and attention deficit hyperac
104 is a commonly occurring symptom in obsessive-compulsive disorder (OCD), and is associated with worse
105 rs (DDs), anxiety disorders (ADs), obsessive-compulsive disorder (OCD), and posttraumatic stress diso
106 y (CBT) is effective for pediatric obsessive-compulsive disorder (OCD), but non-response is common.
107 ognitive behavioral treatments for obsessive-compulsive disorder (OCD), some patients continue to be
108 ated by the ego-dystonic nature of obsessive-compulsive disorder (OCD), where compulsive actions are
110 unction similar to humans with the obsessive-compulsive disorder (OCD)-spectrum disorder, trichotillo
125 utism spectrum disorder [ASD], and obsessive-compulsive disorder [OCD]) share genetic vulnerability a
127 lsive behaviors, characteristic of obsessive-compulsive disorder and addiction, are driven by shared
129 ommon and are suggested to include obsessive-compulsive disorder and behaviours, attention deficit hy
131 nt models of symptom generation in obsessive-compulsive disorder and may enable the development of fu
132 me mental health disorders such as obsessive-compulsive disorder and post-traumatic stress disorder.
133 or asipu; other disorders such as obsessive compulsive disorder and psychopathic behaviour were rega
134 ake inhibitors for childhood-onset obsessive-compulsive disorder and the anxiety disorders, suggest a
135 europsychiatric conditions such as obsessive-compulsive disorder and Tourette syndrome remain uncerta
136 ns are available for management of obsessive-compulsive disorder in adults, but few studies have comp
138 ical basis that schizophrenia with obsessive-compulsive disorder is a distinct subtype of schizophren
144 rge with the effective contacts in obsessive compulsive disorder patients localized within the anteri
147 f posttraumatic stress disorder or obsessive-compulsive disorder to date, although there is evidence
148 ence accumulation in subjects with obsessive-compulsive disorder towards a functional less cautious s
149 ndomized clinical trial (Pediatric Obsessive-Compulsive Disorder Treatment Study for Young Children [
150 ional impulsivity in subjects with obsessive compulsive disorder who have undergone deep brain stimul
151 generalized anxiety disorder, and obsessive-compulsive disorder), substance use disorder (ie, drug a
152 5% CI, 46%-94%) increased risk for obsessive-compulsive disorder, a 21% (95% CI, 11%-33%) increased r
153 specific phobia, agoraphobia, and obsessive-compulsive disorder, all dimensional scores used in the
154 r disorder, depression, addiction, obsessive-compulsive disorder, and anxiety), we found that gray ma
155 ns, including end-of-life anxiety, obsessive-compulsive disorder, and smoking and alcohol dependence,
156 order, agoraphobia, social phobia, obsessive-compulsive disorder, anorexia, or substance abuse), alon
157 s in the etiology and treatment of obsessive-compulsive disorder, anxiety, and depression, emphasizin
159 dition to schizophrenia, including obsessive-compulsive disorder, autism, and alcoholism, occur more
160 is effective in the management of obsessive-compulsive disorder, but considerable uncertainty and li
161 ressiveness and violence in crime, obsessive-compulsive disorder, depression, suicide, schizophrenia,
162 g depression, Parkinson's disease, obsessive-compulsive disorder, essential tremor, addiction, pain,
163 l psychiatric disorders, including obsessive-compulsive disorder, major depressive disorder, posttrau
164 hich is known to be hyperactive in obsessive-compulsive disorder, may be responsible for impairing pa
165 order with or without agoraphobia, obsessive-compulsive disorder, or posttraumatic stress disorder.
166 bia, generalized anxiety disorder, obsessive-compulsive disorder, or social anxiety disorder were ran
167 nt diagnoses of anxiety disorders, obsessive-compulsive disorder, posttraumatic stress disorder, depr
168 ld be paid to anxiety, depression, obsessive-compulsive disorder, psychosis, personality disorders, a
170 with higher levels associated with obsessive-compulsive disorder, schizophrenia, and anxiety disorder
171 pulsive spectrum disorders such as obsessive-compulsive disorder, Tourette's syndrome, pathological g
172 th the model of habit formation in obsessive-compulsive disorder, we hypothesized that this disorder
186 specific phobia, agoraphobia, and obsessive-compulsive disorder; these dimensional scores were resid
187 ICD assessment (Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease short form,
191 fragile X syndrome (FXS), anxiety, obsessive-compulsive disorders, and levodopa induced dyskinesia in
192 chotillomania and trichophagia are obsessive-compulsive disorders, and therefore patients with tricho
193 y impulsivity facilitates the development of compulsive disorders, such as addiction or obsessive com
196 haracterize the addiction phenotype, such as compulsive drug consumption, impaired self-control, and
197 n is a long-lasting disease characterized by compulsive drug intake mediated in part by neuronal and
198 efined as a chronic disease characterized by compulsive drug seeking and episodes of relapse despite
202 at preclinical evidence has shown to predict compulsive drug seeking but has not yet been studied in
204 ial but the relationship of these changes to compulsive drug taking and abstinence is not clear.
211 dividuals switch from controlled drug use to compulsive drug-seeking habits and relapse to these mala
212 ion from voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by
215 ne addiction is characterized by patterns of compulsive drug-taking, including preoccupation with obt
217 omponents and the mechanisms contributing to compulsive eating are not yet clearly defined or underst
221 A major need to improve understanding of compulsive eating through the integration of complex mot
223 and fully blocked food-seeking behavior and compulsive eating, selectively in the Palatable food gro
227 d effortful responding for high-fat diet and compulsive grooming, whereas group-housed female mice di
230 ereating underlying some forms of obesity is compulsive in nature and therefore contains elements of
231 ng, but direct and systematic comparisons of compulsive intake between commonly prescribed opioids an
234 omain-specific memory deficits and increased compulsive-like behaviors, abnormal sensorimotor gating
235 to LHA (GABA) neurons, but without inducing compulsive-like behaviors, which we propose to require d
240 dult rodent brain) during abstinence blocked compulsive-like context-driven methamphetamine reinstate
244 resent study, we evaluated the potential for compulsive-like drug seeking and taking, using intraveno
248 t a functional role for HCRT-R2 signaling in compulsive-like heroin self-administration associated wi
250 We speculate that the striking difference in compulsive-like locomotor behavior is also based on diff
251 Activation of LHA (GABA) neurons induced compulsive-like locomotor behavior; while LHA (Gal) neur
252 te that the development and/or expression of compulsive-like responding for METH under LgA conditions
256 een variously conceptualized as an obsessive-compulsive (OC) spectrum disorder or as an addictive dis
260 motion detection paradigm revealed that high-compulsive participants had a reduced metacognitive abil
261 y, we investigate metacognitive abilities in compulsive participants using computational models, wher
262 amined twenty low-compulsive and twenty high-compulsive participants, recruited from a large populati
264 significantly higher prominence of obsessive-compulsive personality disorder (OCPD) in the FMS group
267 ing and alcohol intake in compulsive and non-compulsive rats, indicating its therapeutic potential to
269 including the modified Yale-Brown Obsessive Compulsive Scale (NE-YBOCS); total scores range from 0 t
272 anges in the Children's Yale-Brown Obsessive Compulsive Scale and Clinical Global Impressions-Severit
274 FB-RT on the Children's Yale-Brown Obsessive Compulsive Scale at week 14 was 0.84 (95% CI, 0.62-1.06)
277 ; corresponding to mean Yale-Brown Obsessive Compulsive Scale score change, -60% [19] vs -11% [9], re
279 point on the Children's Yale-Brown Obsessive Compulsive Scale total score (estimate, -2.31, 95% CI, -
280 lines in the Children's Yale-Brown Obsessive Compulsive Scale total score and Clinical Global Impress
282 y efficacy measure, the Yale-Brown Obsessive Compulsive Scale, of >/=35% over the 3-year follow-up pe
283 oms, measured using the Yale-Brown Obsessive Compulsive Scale-Observer-Rated (Y-BOCS-OR) at 3, 6, and
287 ng gambling disorder, binge eating disorder, compulsive sexual behaviour, and compulsive shopping occ
288 was compulsive eating, followed by punding, compulsive sexual behaviour, gambling and buying disorde
289 g disorder, compulsive sexual behaviour, and compulsive shopping occur in about 17% of patients with
290 to the development and severity of obsessive-compulsive spectrum disorders such as obsessive-compulsi
292 that inhibiting the LH-VTA pathway reduces "compulsive" sucrose seeking but not food consumption in
293 s a neural circuit that selectively controls compulsive sugar consumption, without preventing feeding
294 by showing that schizophrenia and obsessive-compulsive symptoms could be modeled in animals wherein
295 striatum (VC/VS) reduces anxiety, fear, and compulsive symptoms in patients suffering from refractor
296 s of inattention, social deficits, obsessive-compulsive symptoms, and general adaptive functioning we
297 in which patients are repeatedly exposed to compulsive triggers but prevented from expressing their
299 iction end of the spectrum, with evidence of compulsive use and destructive behavior, referral should
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