ライフサイエンスコーパス: concentration response curve

1 llular calcium, allowing the generation of a concentration response curve.

2 his resulted in a leftward shift of the Ca2+ concentration-response curve.

3 homeostasis and pathology on a steep agonist concentration-response curve.

4 r leftward shifts of the acetylcholine (ACh) concentration-response curve.

5 eptor can alter the EC(50) value of the 5-HT concentration-response curve.

6 and 3) allow the measurement of single-cell concentration-response curves.

7 higher concentrations, producing bell-shaped concentration-response curves.

8 hibition, as determined from single chemical concentration-response curves.

9 agonists caused rightward shifts in the PGE2 concentration-response curves.

10 ply through the analysis of their respective concentration-response curves.

11 old to the right the 8-iso-PGE and 8-iso-PGE concentration-response curves.

12 lent cations did not significantly alter ATP concentration-response curves.

13 sthetized male C57BL/6J mice (3 months old), concentration-response curves (10(-9) m to 10(-5) m, 0.5

14 not result in a lateral shift in the agonist concentration-response curve and are unlikely to involve

15 of the high ACh-sensitivity component of the concentration-response curve and contribute directly to

16 Analysis of the CHA concentration-response curve and inhibition of the CHA-i

17 The parameter is derived from agonist concentration-response curves and comprises the maximal

18 Acetylcholine concentration-response curves and maximum function were

19 eceptor tyrosine phosphorylation had similar concentration-response curves and were inhibited by the

20 t 10 to 100 microM, it shifts mGluR5 agonist concentration-response curves approximately 2-fold to th

21 The slope of the underlying in-vitro concentration-response curves contributes as well.

22 The shape of a concentration-response curve (CRC) is determined by unde

23 ntra- and interinhibitor comparisons of dose/concentration response curves demonstrated the absence o

24 Analysis of the CHA concentration-response curves demonstrated that this inc

25 Conversely, the concentration-response curve describing the enhancement

26 Incubation with 3.5 mM Ca2+ shifted the 5-HT concentration-response curve downward and to the right,

27 Whole-cell concentration-response curves enabled the agonists to be

28 ed method for quantifying biomarkers wherein concentration-response curves estimated using samples of

29 and efficacious constrictor, with a biphasic concentration-response curve, followed by vasopressin, s

30 two- to threefold shift to the right in the concentration response curves for arachidonic acid relea

31 n a rightward shift in both the PS- and Ca2+-concentration response curves for PKCalpha membrane asso

32 caused a shift to the right in the collagen concentration response curves for protein tyrosine phosp

33 42A/C296A exhibited no additive shift in the concentration-response curve for 2-MeSADP.

34 ontrast to the wild type A(2A) receptor, the concentration-response curve for agonist-induced cAMP ac

35 The concentration-response curve for alphabeta-MeATP had an

36 The concentration-response curve for ATP on human P2X4 in th

37 RA-2 at 100 nM right-shifted the KCa3.1 concentration-response curve for Ca(2+) activation.

38 trials, has been shown to induce a biphasic concentration-response curve for down-regulating protein

39 -/-)) platelets display an inhibition in the concentration-response curve for GPVI-specific agonist-i

40 Compared with AuIB, the concentration-response curve for inhibition of alpha3bet

41 er than that of ethanol and the slope of the concentration-response curve for isoflurane less steep t

42 The serotonin (2-30 microM) concentration-response curve for LTP was bell shaped as

43 The concentration-response curve for myocyte shortening by t

44 several days with VDH, exhibited a U-shaped concentration-response curve for neuroprotection against

45 ors, Con G produced a rightward shift in the concentration-response curve for NMDA, providing support

46 The flexible ambient concentration-response curve for O3 showed evidence of n

47 The concentration-response curve for oxo-M was shifted to th

48 In preparations from untreated rats, the concentration-response curve for PAD in response to 0.1-

49 uced an apparent noncompetitive shift in the concentration-response curve for spermine potentiation o

50 e pore was supported by a right shift in the concentration-response curve for tetraethylammonium; sim

51 with the enzyme pyruvate kinase, to generate concentration-response curves for >60,000 compounds in a

52 The concentration-response curves for 5-HT and Ang II were s

53 EC(50) values were determined from concentration-response curves for a range of agonists.

54 In the presence of betaAR blockade, concentration-response curves for AR agonists suggest th

55 he Ca(2+), phorbol ester, and diacylglycerol concentration-response curves for Cdc42-induced activati

56 isoforms showed a rightward shift in agonist concentration-response curves for eliciting calcium rele

57 The concentration-response curves for enhancement of steady-

58 ity between these compounds, we examined the concentration-response curves for ethanol and isoflurane

59 Both compounds shifted the concentration-response curves for extracellular Ca2+ to

60 For alpha1beta1delta subunits, concentration-response curves for GABA were displaced la

61 In the contraction experiments, the concentration-response curves for histamine-induced cont

62 hyl acetate leads to rightward shifts in the concentration-response curves for inhibition of [(125)I]

63 ole-cell recording was used to determine the concentration-response curves for lanthanum for the thre

64 Glycine concentration-response curves for NMDARs containing NR2A

65 Comparison of concentration-response curves for presynaptic and postsy

66 Concentration-response curves for reduction in Cmpk by s

67 Comparison of the concentration-response curves for the effects of isoflur

68 IC(50) values were determined from concentration-response curves for three commonly used pu

69 dicated by a parallel rightward shift of the concentration response curve from an EC(50) of 2.7 +/- 0

70 The concentration response curves generated for these end po

71 The concentration-response curves generated by application o

72 TP currents at 100 microM was < 0.1, the ATP concentration-response curve had an EC50 of 56 microM an

73 The Ang II concentration response curves in abdominal aorta and fem

74 atory subunit of the channel, shifts the ATP concentration-response curve into a range in which the c

75 actor for the slope of a quantal, population concentration-response curve is individual variability.

76 SUR2B currents by MgATP explains how the ATP concentration-response curve is shifted to the right in

77 Propofol (3 microM) increased GABA concentration-response curve maximal currents similarly

78 tive-gating modulator and shifts the calcium-concentration response curve of KCa3.1 to the left.

79 A concentration response curve of this blocking agent reve

80 ADP receptor antagonists shifted the concentration-response curve of collagen- or CRP-induced

81 ium chelator 5,5'-dimethyl-BAPTA shifted the concentration-response curve of convulxin-induced platel

82 nonequilibrium conditions we found that the concentration-response curve of pyramidal GABAA receptor

83 124183 caused a marked leftward shift of the concentration-response curve of the A3 receptor agonists

84 s surmountable antagonist rightward-shifting concentration-response curves of all three agonists in a

85 BPTU rightward shifted the concentration-response curves of both 2-methylthioadenos

86 pH (to 8.5) or lowering (to 6.5) shifted the concentration-response curves of GABA to the left or rig

87 Concentration-response curves of intracellular cyclic GM

88 Concentration-response curves of isoproterenol-stimulate

89 s, all of which are based on the analysis of concentration-response curves of ligands according to cl

90 Drug concentration-response curves of neural activity were id

91 Data obtained from concentration-response curves of the volatile anesthetic

92 e rising phase of the glutamate steady state concentration-response curve overlapped with the wildtyp

93 Whole-cell GABA concentration--response curves performed with and withou

94 .2 mM) produced a downward shift of the 5-HT concentration-response curve, reducing the maximal respo

95 Equilibrium concentration-response curves revealed a lower potency f

96 Ca(2+) concentration-response curves revealed that differences

97 Furthermore, cyanopindolol shifted the 5-CT concentration-response curve rightward, increasing the E

98 ng culture media, was complex, with the GABA concentration-response curves shifting laterally with re

99 Equilibrium concentration-response curves showed that recombinant hu

100 gers or ADP receptor antagonists shifted the concentration-response curve slightly to the right at lo

101 Initial estimates based on fitted concentration response curves suggested that maximal inh

102 orrelated with the EC(50) values of the 5-HT concentration-response curves, suggesting that these mut

103 alveolar concentration curve is a population concentration-response curve that describes the relation

104 channels exhibited a monophasic steady state concentration-response curve that simply plateaued at hi

105 lso produced a sinistral displacement of the concentration-response curves that described the augment

106 luK2/GluK4 and GluK2/GluK5 have steady state concentration-response curves that were bell-shaped in r

107 M PGE2 was without significant effect on the concentration response curve to exogenously added acetyl

108 sed GABAA receptors and in shifting the GABA concentration-response curve to lower concentrations.

109 Transfection with bcl-2 shifts the concentration-response curve to NCS but does not change

110 as His and Trp produced a shift of the GABA concentration-response curve to the left, whereas replac

111 slower closing rates, thus shifting the GABA concentration-response curve to the left.

112 T1B autoreceptor but shifted the sumatriptan concentration-response curve to the right (P < 0.05).

113 ncentration of 100 nM, shifted the muscarine concentration-response curve to the right by around 50-f

114 concentration of Waglerin-1 shifted the GABA concentration-response curve to the right in a parallel

115 Zn2+ (100 microM) shifted the ATP concentration-response curve to the right in a parallel

116 IL-2 (2 ng/ml) shifted the kainate concentration-response curve to the right in a parallel

117 dditionally, IL-2 (1 ng/ml) shifted the NMDA concentration-response curve to the right, significantly

118 e channel opening rate and shifting the GABA concentration-response curve to the right.

119 Concentration-response curves to 5-HT2C agonists were fi

120 al pressure on the diameter was assessed and concentration-response curves to different constrictor a

121 r in a video-monitored perfusion system, and concentration-response curves to phenylephrine and acety

122 was also observed to a greater extent on the concentration-response curves to selective hmGluR2/3 ago

123 No obvious difference of the concentration-response curve was found among three group

124 ted group, a non-saturating 5-HT-induced PAD concentration-response curve was generated.

125 The GABA concentration-response curve was shifted to the left by

126 sin; the maximal response was lower, and the concentration-response curve was shifted to the right in

127 Concentration-response curves were classified to rapidly

128 Concentration-response curves were constructed and compa

129 Cumulative concentration-response curves were constructed for Ang I

130 GABA concentration-response curves were depressed in a mixed/

131 r 30 min, and after a 60-min washout period, concentration-response curves were determined for the ad

132 The GABA concentration-response curves were enhanced (pH 5.4) or

133 Using Optimul and LTA, concentration-response curves were generated for arachid

134 The slopes of the concentration-response curves were more shallow than bef

135 Agonist concentration-response curves were similar for all 12 fu

136 ERC concentration-response curves were used across multiple

137 nduce parallel rightward shifts in the VU-29 concentration-response curve, whereas 5MPEP inhibits CPP

138 beta2 nAChRs, as evidenced by monophasic ACh concentration-response curves, whereas injections with 1

139 itive antagonist hybrids produce bell-shaped concentration-response curves, whereas the agonist-compe

140 produced a rightward shift in the CP 93,129 concentration-response curve, while spiperone had no aff

141 sthetic concentrations but there was a sharp concentration-response curve with only minimal effects o

142 Concentration-response curves with Gsalpha suggested the

143 onist-competitive antagonist hybrids produce concentration-response curves with reduced but plateaued

144 roposed approach performed well for 14-point-concentration-response curves with typical levels of res

145 CMPI produced a left shift of the ACh concentration-response curve without altering ACh effica

146 produced a 4-fold rightward shift in the ACh concentration-response curve without altering maximum AC

147 (Emax) of the nACh alpha 7 receptor agonist concentration-response curve, without significantly affe