ライフサイエンスコーパス: conceptus

1 kers are scattered throughout the dab2 (-/-) conceptus.

2 toward the implantation of a semiallogeneic conceptus.

3 E, as well as in the binucleate cells of the conceptus.

4 ined in cultured cells and in the developing conceptus.

5 sm to provide for the growing demands of the conceptus.

6 the effect of origin on the phenotype of the conceptus.

7 own syndrome conceptus than that of a normal conceptus.

8 for the survival of the genetically foreign conceptus.

9 tocyst anticipates the polarity of the later conceptus.

10 contribution of donor allantoic cells to the conceptus.

11 onic and embryonic angioblasts in the murine conceptus.

12 ype depends on the genetic background of the conceptus.

13 ontaneous abortion of a chromosomally normal conceptus.

14 air in assuring the genomic integrity of the conceptus.

15 and plays a pivotal role in programming the conceptus.

16 a (the decidua) that surrounds the implanted conceptus.

17 nutrient availability for the growth of the conceptus.

18 ately 2%) environment of the first trimester conceptus.

19 ifferentiation in the periimplantation ovine conceptus.

20 global role for T in vascularization of the conceptus.

21 ndometrial luminal epithelium but not in the conceptus.

22 but did not occur in ILB2-null (IL1B2(-/-)) conceptuses.

23 it interspecies chimeric competency in mouse conceptuses.

24 in horses carrying interspecies hybrid mule conceptuses.

25 visceral yolk sac of organogenesis-stage rat conceptuses.

26 lfonylated derivatives, were detected in the conceptuses.

27 laced into the base of the allantois of host conceptuses.

28 to BW males produce overgrown but dysmorphic conceptuses.

29 ear trophectoderm cells isolated from day 15 conceptuses.

30 of H19 imprinting persisted in mid-gestation conceptuses.

31 the developing forebrain in humans (1 in 250 conceptuses, 1 in 16,000 live-born infants).

32 in the trophectoderm of the elongating ovine conceptus after day 12 of pregnancy.

33 last giant cells, which are derived from the conceptus and are directly in contact with maternal tiss

34 L) metabolite previously found in the day 10 conceptus and kidneys of vitamin A-deficient rats mainta

35 traembryonic cells that are derived from the conceptus and play a major role in this process.

36 d maternal T cell recognition of the foreign conceptus and subsequent breakdown in maternal-fetal tol

37 equires coordinated interactions between the conceptus and surrounding decidual cells, but the involv

38 al endoderm remains in the distal tip of the conceptus and the ADE fails to form, whereas the node an

39 r disruption of signaling between the cloned conceptus and the endometrium, particularly the intercar

40 etic cells originate from other sites in the conceptus and then colonize the placenta.

41 ene had high expression in porcine and mouse conceptus and throughout placenta development.

42 Finally, when removed from conceptuses and cultured in isolation, neural plate and

43 ects on the survival of both male and female conceptuses and fetuses.

44 nd embryonic vasculopathy in cultured murine conceptuses and in the conceptuses of streptozotocin-ind

45 th Gtl2 during mouse embryogenesis in normal conceptuses and in those with uniparental disomy for chr

46 that the first platelet-forming cells of the conceptus are not megakaryocytes (MKs) but diploid plate

47 In humans, ~50% of conceptuses are chromosomally aneuploid as a consequence

48 The mUPD12 conceptuses are invariably growth-retarded while pUPD12

49 However, conceptus aromatase expression and estrogen secretion we

50 orphological analyses of the Ikbkap(-)(/)(-) conceptus at different stages revealed abnormalities in

51 , a small number of allantoises removed from conceptuses at a considerably earlier stage were found t

52 uring early human placental development, the conceptus attaches itself to the uterus through cytotrop

53 important role in protecting the developing conceptus before it establishes an efficient circulation

54 Hematopoiesis in the mouse conceptus begins in the visceral yolk (VYS), with primit

55 occurred on day 14 in wild-type (IL1B2(+/+)) conceptuses but did not occur in ILB2-null (IL1B2(-/-))

56 MTHFR polymorphism in mothers of trisomy 18 conceptuses but were unable to identify any other signif

57 trophoblast cells promote blood flow to the conceptus by actively remodeling the uterine vasculature

58 stages second polar bodies were attached to conceptuses by a thin, extensible, weakly elastic 'tethe

59 , and that of betaH1-globin, in normal mouse conceptuses by means of in situ hybridization.

60 omplete deletion of Hif1alpha from the mouse conceptus causes extensive placental, vascular and heart

61 t for yeast one-hybrid screening of a day 13 conceptus cDNA library.

62 genetically disparate (allogeneic) mammalian conceptus contradicts the laws of tissue transplantation

63 uced or drug-induced changes in maternal and conceptus copper metabolism, or both.

64 d second cleavage, the second polar body and conceptus could remain coupled ionically up to the blast

65 Use of MAO-SLC7A1 knockdown in conceptuses decreased arginine transport (73%, P<0.01),

66 al development and fetal growth, we examined conceptuses developing in the absence of maternally deri

67 mpensation that may result in differences in conceptus development across species.

68 nockdown of SLC7A1 mRNA resulted in retarded conceptus development and abnormal function compared to

69 lase and agmatinase were activated to rescue conceptus development.

70 s critical in supporting the early stages of conceptus development.

71 ses was inhibited, expression of a number of conceptus developmental genes was not altered.

72 gly, mares carrying interspecies hybrid mule conceptuses did not exhibit this transient, pregnancy-as

73 netic background, approximately 50% Tgfb1-/- conceptuses die midgestation from defective yolk sac vas

74 plantation mouse embryo to that of the later conceptus due to the lack of markers that endure long en

75 polar bodies relative to the surface of the conceptus during either cleavage or blastulation.

76 The first known hormonal signal of the conceptus during implantation is human chorionic gonadot

77 tory response of endometrium to IL1B2 during conceptus elongation and attachment to the uterine surfa

78 oach retarded trophectoderm outgrowth during conceptus elongation and inhibited trophoblast giant bin

79 onceptus trophectoderm and are essential for conceptus elongation and trophectoderm growth and develo

80 nd the secretion of IL1B2 during the time of conceptus elongation.

81 les of arginine within the uterine lumen for conceptus (embryo and extraembryonic membranes) developm

82 and differentiation in the periimplantation conceptus (embryo/fetus and associated extraembryonic me

83 he uterus support survival and growth of the conceptus (embryo/fetus and associated membranes) during

84 rone and might support a role for enJSRVs in conceptus-endometrium interactions during the peri-impla

85 In day 17 and 19 conceptuses, enJSRV RNAs were also detected in binucleat

86 e involved in the spatiotemporal increase in conceptus estrogen synthesis needed for the establishmen

87 are invariably growth-retarded while pUPD12 conceptuses exhibit placentomegaly.

88 Conceptus expansion throughout the uterus of mammalian s

89 CRP, official gene symbol ABCG2) protect the conceptus from exposure to toxins and xenobiotics presen

90 Analysis of post-implantation conceptuses from embryonic day (E)9.5 to E13.5 revealed

91 By day 90, however, placentae of conceptuses from the high PE group expressed greater (P

92 and VEGF-R2 mRNA expression in day 70 and 90 conceptuses from Yorkshire females selected for high PE,

93 ng that although the signals that coordinate conceptus growth are similar between rodents and pigs, t

94 roperties, fed to a/a dams harboring A(vy)/a conceptuses has been reported to induce a significant sh

95 Mouse conceptuses homozygous for mutations in brachyury (T) ex

96 Conceptuses homozygous for the T(Curtailed) (T(C)) mutat

97 /Cas9 gene editing was used to knock out pig conceptus IL1B2 expression and the secretion of IL1B2 du

98 In most successful human pregnancies, the conceptus implants 8 to 10 days after ovulation.

99 aternal immune recognition of the developing conceptus in equine pregnancy is characterized by the st

100 pe," are at a competitive advantage over a/a conceptuses in certain uterine environments.

101 A greater (P < 0.05) PE was observed for conceptuses in the high PE selection group when compared

102 and might therefore coordinate growth of the conceptus, including the imprinted Igf2 and Grb10 genes.

103 nancy loss because of the development of the conceptus into a complete hydatidiform mole in which ext

104 mmetry into the axes of the postimplantation conceptus involves asymmetric visceral endoderm cell mov

105 Implantation of the conceptus is a key step in pregnancy, but little is know

106 w days during the time at which the ruminant conceptus is first establishing intimate contacts with t

107 is uncertain when during pregnancy the human conceptus is most vulnerable to the virus.

108 l number of definitive HSC/RUs in the entire conceptus is only about 3.

109 ands and blood vessels by angioblasts in the conceptus, is a dynamic process modulated, in part, by c

110 Conceptuses lacking an embryo proper are also observed a

111 epiblast or visceral endoderm layers of the conceptus leads to apoptosis and inhibition of embryo gr

112 rganized visceral endoderm in Dab2-deficient conceptus leads to the growth failure of the inner cell

113 hree major vascular systems in the mammalian conceptus, little is known about the murine allantois, w

114 rnally derived population of free trisomy 21 conceptuses ( n = 67).

115 reduced risk for a recognized Down syndrome conceptus (odds ratio (OR) = 0.54; 95% confidence interv

116 imitive trophoblast, which may put the early conceptus of an infected mother at high risk for destruc

117 hy in cultured murine conceptuses and in the conceptuses of streptozotocin-induced diabetic pregnant

118 astocyst stage in nearly two-thirds of mouse conceptuses of the PO strain.

119 l endoderm, leads to posteriorization of the conceptus or failure to elongate the anteroposterior axi

120 entomes of infected ewes pregnant with 171QR conceptuses or in the non-pregnant uterus of infected ew

121 n's age or parity, the size or volume of the conceptus, or the presence of fluid in the peritoneal ca

122 In mutant conceptuses, placental areas were approximately 50% less

123 seq) to compare the transcriptomes in cattle conceptuses produced by SCNT and artificial insemination

124 Conceptus production of a unique interleukin 1beta, IL1B

125 ds into blood islands of headfold-stage host conceptuses provided no evidence that the yolk sac contr

126 rors in meiosis, and most of these aneuploid conceptuses result in spontaneous miscarriage.

127 Subsequent whole embryo culture of operated conceptuses resulted in the formation of regenerated all

128 f microdissected trophectoderm of the bovine conceptuses revealed the presence of enJSRV RNA and, in

129 To determine effects of conceptus secretory proteins (CSP) containing IFN-delta

130 Placentas from all conceptuses showed expression of the transgene as detect

131 Analysis of spontaneously aborted conceptuses shows that CMV infects the placenta before t

132 Examination of Dnmt3l(-/+) conceptuses shows that imprinted expression for all gene

133 he hyperglycemia-induced vasculopathy in the conceptus support the concept that VEGF levels can be mo

134 s, by catabolizing tryptophan, the mammalian conceptus suppresses T cell activity and defends itself

135 metrial function and receptivity, to enhance conceptus survival and development, and to evaluate and

136 conceptus Tr, and arginine is essential for conceptus survival and development.

137 ults support a "bottleneck" model for cloned conceptus survival during the periimplantation period de

138 ast and placental development, and/or affect conceptus survival in mice.

139 In NIH/Ola, C57BL/6J/Ola and F1 conceptuses, Tgfb1-/- lethality can be categorized into

140 y to reduce the viability of a Down syndrome conceptus than that of a normal conceptus.

141 Among the 102 conceptuses that implanted by the ninth day, 13 percent

142 eration in the vascular regions of the mouse conceptus-the aorta, vitelline and umbilical arteries, y

143 polar body normally remains attached to the conceptus through persistence of the intercellular bridg

144 and an absence of IL-22 expression in other conceptus tissues.

145 This tumor-like process anchors the conceptus to the mother and diverts the flow of uterine

146 This process attaches the conceptus to the uterine wall and starts the flow of mat

147 rial infections likely alter exposure of the conceptus to toxins and drugs during early pregnancy, wh

148 effects of estrogens, which are secreted by conceptuses to prevent corpus luteum regression, nonpreg

149 SLC7A1 is the key transporter of arginine by conceptus Tr, and arginine is essential for conceptus su

150 nclusion bodies in endometrial epithelia and conceptus Tr.

151 C7A1 mRNA, the arginine transporter in ovine conceptus trophectoderm (Tr).

152 screte cytoplasmic crystalline structures of conceptus trophectoderm (Tr).

153 al and glandular epithelia as well as in the conceptus trophectoderm and are essential for conceptus

154 of arginine transporter SLC7A1 mRNA in ovine conceptus trophectoderm.

155 ne lumen and could potentially transduce the conceptus trophectoderm.

156 ed enJSRV envelope protein production in the conceptus trophectoderm.

157 ight be affected by the presence of a cloned conceptus, ultimately leading to mortality before or dur

158 Pig conceptuses undergo a unique rapid morphological transfo

159 arly somite stages (E7.25 to E8.5), when the conceptus undergoes rapid morphologic changes with forma

160 onic and embryonic angioblasts in the murine conceptus using both in vitro and in vivo models.

161 In E5.5 dab2 (-/-) conceptus, visceral endoderm-like cells are present in t

162 e found that development of the experimental conceptus was affected, at least in part, by a lack of g

163 toises grow and differentiate outside of the conceptus was investigated.

164 leptin, demonstrating that the heterozygous conceptus was not the source of the leptin.

165 h the morphological transition of IL1B2(-/-) conceptuses was inhibited, expression of a number of con

166 e tissue for survival and development of the conceptus, we conducted an in vivo morpholino antisense

167 The first GP1bbeta-positive cells in the conceptus were identified in the yolk sac at E9.5, while

168 After 23 hours in culture, operated conceptuses were examined histologically for contributio

169 tionship was also seen when denuded two-cell conceptuses were prevented from rotating during subseque

170 ic day 19, placental and fetal weights in P0 conceptuses were reduced to 66% and 76%, respectively, o

171 es were affected by the presence of a cloned conceptus, whereas at d 34, approximately 36% and <0.7%

172 t results in reduced levels of VEGF-A in the conceptus, which in turn, leads to abnormal VEGF recepto

173 Data suggest that A(vy)/a conceptuses, which may possess a so-called "thrifty geno

174 f infected ewes are not pregnant or conceive conceptuses with a resistant PrP genotype.

175 Using conceptuses with maternal or paternal uniparental disomy

176 sential role of this gene suggests that male conceptuses with these variants may not be viable.

177 We have therefore generated conceptuses with uniparental disomy for chromosome 12, i