ライフサイエンスコーパス: concerted action of

1 replication depend on the direct linkage and concerted action of 1a's self-interacting capping and he

2 ng multiple overlapping DNA molecules by the concerted action of a 5' exonuclease, a DNA polymerase a

3 Therefore, we propose that only the concerted action of a combination of inhibitory receptor

4 ted ATPase activity and gating depend on the concerted action of a full complement of Rpt subunits co

5 Selenocysteine incorporation requires the concerted action of a kink-turn structural RNA (SECIS) e

6 ion repair (NER) in yeast is effected by the concerted action of a large complex of proteins.

7 This event requires the concerted action of a large number of fusion-competent s

8 The concerted action of a large number of individual molecul

9 borate biochemical process that requires the concerted action of a large set of transcription factors

10 highly coordinated process that requires the concerted action of a large, dynamic, ribonucleoprotein

11 ration in vitro, which is carried out by the concerted action of a novel Sec incorporation domain and

12 targeted for proteasomal degradation by the concerted action of a SUMO-targeted ubiquitin ligase (ST

13 st paramyxoviruses infect host cells via the concerted action of a tetrameric attachment protein (var

14 lization of these alpha-glucans requires the concerted action of a variety of enzymes, including glyc

15 and exocytosis, whereas cytokinesis requires concerted actions of a contractile actomyosin ring and t

16 rimarily at the transcriptional level by the concerted actions of a limited number of hepatocyte-enri

17 port is a finely tuned process requiring the concerted actions of a number of accessory factors.

18 interactions are mediated by elaboration and concerted actions of a variety of growth and differentia

19 rameters are maintained and regulated by the concerted action of all components under a diverse range

20 ntly can control a single gate formed by the concerted action of all four Kir6.2 subunit inner helice

21 actic cell migration on Ln-5 is regulated by concerted action of alpha 3beta 1 and alpha 6 beta 4 int

22 These studies suggest a mechanism for the concerted action of alpha-toxin and PFO during C. perfri

23 We demonstrate that a concerted action of an anionic cholesterol derivative, c

24 ll division in Escherichia coli requires the concerted action of at least 10 essential proteins.

25 rephosphorylated and inactivated through the concerted action of at least 3 different kinases: CK1, G

26 The herpesvirus entry machinery requires the concerted action of at least four glycoproteins; however

27 phosphosulfate (PAPS), is synthesized by the concerted action of ATP sulfurylase and adenosine 5'-pho

28 in a complex environment and are guided by a concerted action of attractive and repulsive factors to

29 This behavior resulted from the concerted actions of axo-somatic sodium channels that in

30 eta-amyloid precursor proteins (APP), by the concerted action of beta- and gamma-secretase(s).

31 gram during early tooth development requires concerted actions of Bmp, Fgf and Wnt signaling from the

32 n response to abiotic stress, which requires concerted action of both cis- and trans-regulatory featu

33 plete recovery of DNA synthesis requires the concerted action of both pol II and pol III.

34 actor receptor (EGFR) signaling requires the concerted action of both positive and negative factors.

35 The concerted action of both positive feedback loops resulte

36 Furthermore, stimulation is dependent on the concerted action of both Rad51 protein and RPA, implying

37 Concerted action of both regions sustains responses to d

38 tringent aerobic repression results from the concerted action of both.

39 NIK cleavage requires the concerted actions of both fusion partners and generates

40 represents a gain of function requiring the concerted actions of both the API2 and MALT1 moieties of

41 3' alpha E (hs1,2) is down-regulated by the concerted actions of BSAP, octamer, and G-rich DNA-bindi

42 Exocytotic secretion is promoted by the concerted action of calcium, guanine nucleotide, and pro

43 Thus, the concerted action of calcium- and voltage-activated potas

44 Apoptosis is orchestrated by the concerted action of caspases, activated in a minimal two

45 We propose that the concerted action of Cdc28/Cdk1 and Cdc5/Polo on their co

46 e mammary-specific casein genes requires the concerted action of chromatin remodeling enzymes and tra

47 per se but is most likely the result of the concerted action of coactivator proteins recruited by th

48 ow that cueP expression is controlled by the concerted action of CueR, which detects the presence of

49 The concerted action of CVF and CPA significantly increases

50 y cyanophycin synthetase and degraded by the concerted action of cyanophycinase (that releases beta-a

51 ent that growth cone guidance depends on the concerted actions of cytoskeletal proteins, molecular mo

52 Activation of BAX through the concerted action of cytosolic p53 and Pin1 may integrate

53 Taken together, we propose that the concerted action of DDK, Polo-like kinase, and CDK1 prom

54 NCRs are targeted to the endosymbionts, and concerted action of different sets of peptides governs d

55 transcriptional induction is mediated by the concerted action of different transcription factor famil

56 yotic DNA replication fidelity relies on the concerted action of DNA polymerase nucleotide selectivit

57 intenance of genomic stability relies on the concerted action of DNA repair and DNA damage signaling

58 We show the concerted actions of DNMT enzymes in the establishment a

59 occurs in sequential steps and requires the concerted action of E2 conjugating proteins and E3 ligas

60 hanism of colonization that results from the concerted action of effector proteins translocated into

61 y converge during beta-selection through the concerted action of Egr1 and NF-ATc1, respectively.

62 otein coding genes in metazoans involves the concerted action of enhancer binding proteins and the RN

63 Chromosomal transcription involves the concerted action of enormous, multisubunit chromatin rem

64 at PMS2 defective lymphomas may arise by the concerted action of environmental and perhaps endogenous

65 Concerted actions of estrogen and progesterone via their

66 abolished T cell recognition; for others, a concerted action of evasins was required to abrogate rec

67 A model is presented to explain how the concerted action of EXO and GEN activities may contribut

68 ross-links on DNA, most likely employing its concerted action of exonuclease and gap-dependent endonu

69 e present study, we test the hypothesis that concerted action of exonuclease and gap-dependent endonu

70 Stem cell self-renewal is controlled by concerted actions of extrinsic niche signals and intrins

71 ion implies that synergy can result from the concerted action of factors stimulating two different st

72 We have studied the concerted action of factors that influence the balance b

73 Thus, our data show how the concerted actions of FGF13 and FGF14 regulate the polari

74 ement of the Beet yellows virus requires the concerted action of five viral proteins including a homo

75 g embryonic morphogenesis is mediated by the concerted action of four proteins that delay the formati

76 Thus, the concerted actions of GABAergic inhibition from three Apl

77 ctivity of which seems to be mediated by the concerted action of GATA and IRF proteins.

78 /220 for initial attachment, followed by the concerted action of gH, gL, gB, and gp42 for membrane fu

79 an a week after exposure to stress, required concerted action of glucocorticoids and catecholamines a

80 ane fusion and secretion are promoted by the concerted action of GTP and Ca2+, although the precise s

81 cient duplication of the genome requires the concerted action of helicase and DNA polymerases at repl

82 rthermore, they identify a strategy by which concerted actions of histone deacetylases and other co-r

83 PG sacculus is a dynamic event requiring the concerted action of hydrolases that cleave the cross-lin

84 cat ventrobasal thalamus is mediated by the concerted action of Ih and a Ba(2+)-sensitive current wi

85 anical hyperalgesia that is generated by the concerted action of inflammatory mediators present in in

86 The concerted action of inositol 1,4,5-trisphosphate (IP3) a

87 nce of adaptive immune responses through the concerted action of interferon-stimulated genes (ISGs).

88 Our results highlight that the concerted action of Isw1 and the nuclear exosome ensures

89 pUL83 disrupts IFI16 by concerted action of its N- and C-terminal domains, in wh

90 is, cell migration, and ERK signaling by the concerted action of its proline-rich region (PRR), RhoGA

91 This fusion results from the concerted action of its two envelope glycoproteins, the

92 The concerted action of JAK kinases, members of the Src-kina

93 During homeostasis, the concerted action of local niche signals and epigenetic r

94 l model of spore inhalation and clearance by concerted actions of macrophages and neutrophils, and us

95 Good additivity was found for the concerted action of magainin 2, the fungicidal lipopepti

96 ial developmental response that involves the concerted action of many different cell types, is highly

97 etic and environmental cues and requires the concerted action of many genes.

98 iated fear-memory enhancement results from a concerted action of mechanisms that strengthen memory th

99 results are important for understanding the concerted action of membrane-permeabilizing compounds in

100 creening methods are essential to define the concerted actions of miRNAs in cardiovascular disease.

101 se entry in metazoans with open mitosis, the concerted action of mitotic kinases disassembles nuclei

102 proteins across cellular membranes with the concerted action of mostly three membrane proteins: TatA

103 We suggest that the concerted action of MtuMutT1 and Rv1700 plays a crucial

104 The mechanism may involve the concerted action of multiple antiretroviral effectors co

105 te that dynein recruitment to cargo requires concerted action of multiple dynein cofactors.

106 ession of HCV replication is mediated by the concerted action of multiple effectors.

107 While concerted action of multiple elements of the immune syst

108 icrobial phenotypes are typically due to the concerted action of multiple gene functions, yet the pre

109 The concerted action of multiple hydrogen bonds keeps the te

110 Tumorigenesis requires the concerted action of multiple pathways, including pathway

111 gulation is a complex process, involving the concerted action of multiple physiologically relevant ef

112 membrane curvature induction depends on the concerted action of multiple proteins, controlling the l

113 ar matrix (ECM) remodeling, which requires a concerted action of multiple proteolytic enzymes and the

114 king during synaptic plasticity requires the concerted action of multiple signaling pathways and the

115 hemokine signals may be mediated through the concerted action of multiple suppressive pathways that p

116 Our results therefore demonstrate the concerted action of multiple synaptic mechanisms for rob

117 The regulation of transcription involves the concerted action of multiple transcription factors (TFs)

118 cles to transcription may be overcome by the concerted actions of multiple accessory factors.

119 l protein S6 kinase is regulated through the concerted actions of multiple phosphatases and kinases.

120 velopment of the nervous system requires the concerted actions of multiple transcription factors, yet

121 minant pathways are defined that require the concerted action of multivalent membrane Ig cross-linkin

122 acellular membrane fusion is mediated by the concerted action of N-ethylmaleimide-sensitive factor at

123 urs relatively slowly and is mediated by the concerted actions of natural IgM and complement.

124 Stem cell self-renewal is controlled by concerted actions of niche signals and intrinsic factors

125 uration of the second P-cluster requires the concerted action of NifZ, Fe protein, and MgATP and that

126 se results reveal a fundamental role for the concerted action of NO and O2 in physiological regulatio

127 adrenergic activation, are regulated through concerted actions of NO synthase/GSNOR and that aberrant

128 rosine nitration and loss of activity by the concerted action of NOS-3 and XO were also confirmed in

129 ellular repair capacity by orchestrating the concerted actions of nucleotide excision repair (NER) an

130 is a dynamic process that is governed by the concerted action of numerous cell cycle regulatory prote

131 cellular function, and is maintained by the concerted action of numerous nuclear proteins, including

132 f breast cancer cells was achieved through a concerted action of OM on cell cycle components.

133 e-RC), which is loaded onto chromatin by the concerted action of origin recognition complex, Cdc6, an

134 Osteoclast formation depends on the concerted action of osteoblast-derived receptor activato

135 Strikingly, the concerted action of p53 and POLiota decelerates nascent

136 y controlling the expression of Pax3 and the concerted action of Pax3 and Sox10 on their target genes

137 This can be achieved by a concerted action of peptidoglycan (PG) hydrolases and PG

138 rly coded proteins Pet309p, Pet111p, and the concerted action of Pet54p, Pet122p, and Pet494p, respec

139 ar matrix (ECM) organization and require the concerted action of planar cell polarity (PCP) proteins

140 )K27 H3 histone modifications created by the concerted action of Polycomb (PcG) and Trithorax histone

141 or single S5-6 region was replaced suggest a concerted action of pore-lining regions in the control o

142 Concerted action of priming and activating amino acids i

143 malian cells through G1 is controlled by the concerted action of protein kinases, the activities of w

144 -infected and tumor cell targets through the concerted action of proteins contained in cytolytic gran

145 The concerted actions of PRR signaling, specific viral-restr

146 ecQ but not with UvrD helicase, suggesting a concerted action of RecQ helicases and pol delta.

147 ating is a cooperative process involving the concerted action of residues from more than a single pro

148 Our data showed that the concerted action of Rho and Rac modulate the establishme

149 precursors is regulated by actin and by the concerted action of Rho- and p21-activated kinases.

150 associated siRNAs involves the noncanonical, concerted action of RNA POLYMERASE IV, RNA-DEPENDENT RNA

151 umulation during inflammation depends on the concerted action of selectin and integrin adhesion molec

152 n iron homeostasis is maintained through the concerted action of sensory and regulatory networks that

153 e expression during development requires the concerted action of sequence-specific transcriptional re

154 Drosophila compound eye is specified by the concerted action of seven nuclear factors that include E

155 cell homing to the bone marrow requires the concerted action of several adhesion molecules.

156 The concerted action of several cytokines is necessary for r

157 that transgene locus formation involves the concerted action of several DNA break-repair mechanisms.

158 c(2) N-glycan structures is catalyzed by the concerted action of several exoglycosidases, including a

159 lum-Golgi complex-trans-Golgi network by the concerted action of several glycosyltransferases, an epi

160 Although many genes are regulated by the concerted action of several hormones, hormonal signaling

161 in (Blimp)-1-dependent program involving the concerted action of several proplasma transcriptional re

162 Eukaryotic DNA mismatch repair requires the concerted action of several proteins, including prolifer

163 ular inflammation and thrombosis require the concerted actions of several different agonists, many of

164 The concerted actions of Shh and Bmp7 can direct mouse embry

165 and self-renewal--whose balance requires the concerted action of signal transduction pathways, transc

166 Mammalian organogenesis results from the concerted actions of signaling pathways in progenitor ce

167 educes their expression levels, suggesting a concerted action of Smad2 and -4 in regulating TGF-beta

168 eaction in regulated exocytosis requires the concerted action of soluble N-ethylmaleimide-sensitive f

169 lesions during genomic replication requires concerted actions of specialized DNA polymerases in a po

170 that transcriptional activation through the concerted action of SREBP and Sp1 can occur by at least

171 cholesterol synthesis are stimulated by the concerted action of SREBPs along with coregulators that

172 ll self-renewal is tightly controlled by the concerted action of stem cell-intrinsic factors and sign

173 li, PI-1 and PI-2, both of which require the concerted action of structural proteins and sortases for

174 dence for molecular mechanisms involving the concerted actions of SUD-M and SUD-C, which result in sp

175 nance of female sexual identity requires the concerted actions of Sxl and bam.

176 Our results highlight the concerted actions of synaptic excitation and inhibition

177 us type 1 (HTLV-1) expression depends on the concerted action of Tax, which drives transcription of t

178 Expression of the virus depends on the concerted action of Tax, which drives transcription of t

179 FPR-blocked and active thrombin indicated a concerted action of the active site and exosite I during

180 is in Saccharomyces cerevisiae occurs by the concerted action of the actomyosin system and septum for

181 ar dopamine levels and is metabolized by the concerted action of the aromatic amino acid decarboxylas

182 Plant root development is mediated by the concerted action of the auxin and cytokinin phytohormone

183 atterning of vertebrate embryos requires the concerted action of the Bone Morphogenetic Protein (BMP)

184 s from Saccharomyces cerevisiae involves the concerted action of the cap-binding protein eIF4E and th

185 Our results allow us to propose a concerted action of the four conserved cysteines of VKOR

186 nvelope with the plasma membrane through the concerted action of the fusion (F) protein and the recep

187 Carbamoyl phosphate synthesis requires the concerted action of the glutaminase (GLN) and carbamoyl-

188 on, and will be useful for understanding the concerted action of the mechanisms that drive self-assem

189 scade reactions, less is known about how the concerted action of the microvilli population encodes li

190 ibosylnicotinamide to NAD which involves the concerted action of the PnuC transporter and NRK, follow

191 lyl conformers that can be interconverted by concerted action of the RBD4 and CY domains of RanBP2.

192 Here, we show that the concerted action of the RecFOR complex directs the loadi

193 SRP1/pY is recycled from the ribosome by the concerted action of the ribosome-recycling factor (RRF)

194 , and a deacylated tRNA, is processed by the concerted action of the ribosome-recycling factor (RRF),

195 proteasome-dependent degradation due to the concerted action of the scaffolding protein Axin and its

196 class of effector molecules dependent on the concerted action of the SH3, SH2, and catalytic domains

197 the endoplasmic reticulum is mediated by the concerted action of the signal recognition particle (SRP

198 holesterol homeostasis is maintained through concerted action of the SREBPs and LXRs.

199 Paramyxoviruses initiate entry through the concerted action of the tetrameric attachment glycoprote

200 e cytokinetic Z ring at midcell requires the concerted action of the three Min proteins.

201 These results indicated that the concerted action of the three mutated residues (D86A, E8

202 Depending on the oxygen tension, a concerted action of the three transcription factors regu

203 We have studied the concerted action of the three underlying mechanisms, nam

204 an early progenitor stage, indicating that a concerted action of the transcription factor Runx1, toge

205 ynthesis of carbamoyl phosphate requires the concerted action of the two active sites within the homo

206 hesis and cell shape maintenance require the concerted actions of the CrgA, Rv0008c, FtsI, and Wag31

207 t takes several hours and is mediated by the concerted actions of the group IV cytosolic phospholipas

208 g nicking and powered by ATP hydrolysis, the concerted actions of the helicase and nuclease domains o

209 osphatidylinositol at its site of use by the concerted actions of the phosphoinositide kinases and PL

210 on epigenetic regulation carried out by the concerted actions of the Polycomb and Trithorax group of

211 cytoskeletal structures by orchestrating the concerted actions of the triumvirate of SphK1, FLNa, and

212 sing the viral and target cell membranes via concerted action of their two envelope glycoproteins: th

213 formation is most likely orchestrated by the concerted action of these different parts of the protein

214 ensity of docked vesicles, suggesting that a concerted action of these mechanisms underlies the funct

215 of events in wild-type cells, demonstrate a concerted action of these proteins prior to, and indepen

216 The concerted actions of these enzymes largely determine the

217 majority of proteins in mammalian cells by a concerted action of three distinct pairs of active sites

218 s, this process is tightly controlled by the concerted action of three G proteins, the 54-kD subunit

219 of herpes simplex virus is regulated by the concerted action of three immediate-early (alpha) protei

220 The repression of transcription, through the concerted actions of tissue specific DNA binding protein

221 olycistronic mRNAs that are dissected by the concerted action of trans-splicing and polyadenylation.

222 activation in higher eukaryotes requires the concerted action of transcription factors and coactivato

223 pecification and commitment is driven by the concerted action of transcription factors and IL-7 signa

224 This reaction is a result of the concerted action of two catalytic domains of FDH, the am

225 for selective histone exchange that uses the concerted action of two distinct chromatin-remodeling en

226 of the Paramyxovirinae subfamily rely on the concerted action of two envelope glycoprotein complexes,

227 Here we show that the concerted action of two enzymes commonly involved in nat

228 es its direct interaction with Bim1p and the concerted action of two MT motors-Kip3p and dynein.

229 rrelations can be explained as a result of a concerted action of two mutation mechanisms, which we na

230 ontrol the timing of output pathways via the concerted action of two oppositely acting enzymes.

231 are segregated at cell division involves the concerted action of two plasmid-encoded proteins that as

232 Fusion is orchestrated via the concerted action of two surface glycoproteins: an attach

233 is B cell fate decision is determined by the concerted action of two surface proteins on activated T

234 d a complex polyferredoxin, each require the concerted action of two translocases for their assembly.

235 f enveloped viruses enters cells through the concerted action of two viral glycoproteins.

236 c cycling, which is tightly regulated by the concerted actions of two highly conserved enzymes, serve

237 our knowledge, a possible mechanism for the concerted action of tyrosine kinases, GIT1/betaPIX prote

238 Ubiquitination is mediated by the concerted action of ubiquitin-conjugating enzymes (Ubcs

239 extricated from the clathrin lattice by the concerted action of up to six Hsc70 molecules, which int

240 This process requires the concerted action of various proteins, including Apg5p.

241 nscribed in infected plant cells through the concerted action of viral and host factors.

242 action potential (AP) is transmitted by the concerted action of voltage-gated ion channels.

243 uning of persistent activity arises from the concerted action of widespread inhibition mediated by pe

244 while viral genome replication requires the concerted action of Zta and six other viral proteins at