ライフサイエンスコーパス: conditional lethal

1 that previously obtained with an inducible, conditional lethal A30L mutant.

2 cation of BBP1 in a suppressor screen with a conditional lethal allele of SPC29.

3 and bub3 as well as a limited subset of tub1 conditional-lethal alleles.

4 al single and double mutations are lethal or conditional lethal and cause a block before the first st

5 , seven were recessive-lethal and three were conditional-lethal and caused severe actin organization

6 ent to suppress the growth phenotype of both conditional-lethal and null S. pombe crm1(-) mutant stra

7 A single copy of a conditional lethal C. neoformans NMT allele was introduc

8 Cells carrying the conditional lethal cdc28-P8 mutation divide once and arr

9 Previously, we described a conditional lethal Deltahgprt/Deltaxprt mutant of L. don

10 living world should make streptavidin-based conditional lethal designs applicable to a broad range o

11 on, could complement a temperature-sensitive conditional lethal dnaE mutation.

12 judged by their abilities to complement the conditional lethal E. coli birA mutant.

13 y of the enzyme and potential use as a novel conditional lethal gene in plants are discussed.

14 l utility of the pehA gene as a heterologous conditional lethal gene in plants is discussed.

15 ester hydrolase was evaluated in plants as a conditional lethal gene useful for cell ablation and neg

16 proaches that included use of sterile males, conditional lethal genes, translocations, compound chrom

17 We have introduced a conditional lethal genetic element into HIV-1 and simian

18 ce complex stability and result in lethal or conditional lethal growth defects.

19 vaccinia virus genes are often studied with conditional-lethal inducible mutants.

20 in viral assembly or infectivity, we made a conditional-lethal inducible recombinant vaccinia virus.

21 The serendipitous discovery of the conditional lethals is also described.

22 ains and expose this motif restore growth to conditional-lethal MCM10 mutant cells.

23 dy (SPB) component Cut12 both suppresses the conditional lethal mitotic commitment defect of cdc25.22

24 report of the generation of a B. burgdorferi conditional lethal mutant equivalent by tetracycline-con

25 f the putative I7 protease, we constructed a conditional lethal mutant in which the I7L gene was regu

26 The phenotype of the L5R conditional lethal mutant is identical to that of recent

27 Phenotypic characterization of the conditional lethal mutant showed that at permissive grow

28 A conditional lethal mutant virus was constructed by placi

29 rder to study the role of the G7L protein, a conditional lethal mutant was made by replacing the G7L

30 the A30L protein, we constructed a stringent conditional lethal mutant with an inducible A30L gene.

31 A conditional lethal mutant, in which A21L gene expression

32 Using a conditional-lethal mutant allele of SUP45 (sup45-2) and

33 Incubation of this conditional-lethal mutant at the nonpermissive temperatu

34 asibility of using chemical rescue to make a conditional-lethal mutant of the cytomegalovirus (CMV) m

35 A conditional-lethal mutant was isolated as having a flage

36 The pathway was defined by analyzing conditional lethal mutants and effects of cysteine to se

37 Thus, it is now possible to create conditional lethal mutants and study the terminal phenot

38 The phenotype of L2 conditional lethal mutants and the localization of L2 su

39 These conditional lethal mutants arrest with unsegregated chro

40 conditions would enable the construction of conditional lethal mutants in essential genes, and permi

41 Eighteen lethal and conditional lethal mutants were genetically and biochemi

42 The conditional lethal mutants, bearing cold-sensitive (cs)

43 In addition, a mutant with a conditional lethal mutation in lpxC, an essential gene r

44 ntragenic suppressors of LG4, a virus with a conditional lethal mutation in the gene encoding ICP27.

45 This plant carries a semidominant, conditional lethal mutation that confers constitutive ex

46 We have isolated a new conditional-lethal mutation, ndc10-2, in the NDC10/CBF2/

47 genome wide dosage suppressor analysis of 53 conditional lethal mutations in cell division cycle and

48 Here we describe new myo2 alleles containing conditional lethal mutations in the COOH-terminal tail d

49 Conditional lethal mutations inserted into mosquito geno

50 Here, we use temperature-sensitive (ts) conditional lethal mutations of the S. cerevisiae POL2 a

51 Early screens for conditional lethal mutations that affected rRNA expressi

52 gate its functions, a series of absolute and conditional lethal mutations were generated.

53 Classes of mutants include conditional lethal mutations, conditional auxotrophs, an

54 ne-scanning mutagenesis was used to generate conditional-lethal mutations in hitherto-uncharacterized

55 In conditional lethal nud1-2 cells, the MEN component Tem1p

56 Studies with conditional-lethal null mutants indicated that the viral

57 ultaneous absence of BamB and BamE confers a conditional lethal phenotype and a severe beta-barrel ou

58 between shm1-1 and shm1-2 displayed the same conditional lethal phenotype as shm1-1.

59 ong-chain fatty acids and suppression of the conditional lethal phenotype by high sucrose and NaCl co

60 perone activity of HflB and reveals that the conditional lethal phenotype for hflB is cold sensitivit

61 isolated three multicopy suppressors of the conditional lethal phenotype of a prc (tsp) null strain

62 e demonstrated its ability to complement the conditional lethal phenotype of an S. cerevisiae cdc9 mu

63 We demonstrate that the conditional lethal phenotype of bimG11 strains is due to

64 The synthetic conditional lethal phenotype of Delta cpxR in mutant Bam

65 ression suppresses the temperature-sensitive conditional lethal phenotype of smc2-6, but not smc2-8 o

66 er, neither of these defects can explain the conditional lethal phenotype of the ski6-100 strain.

67 echocystis sp. strain PCC 6803 resulted in a conditional lethal phenotype with a pleiotropic effect o

68 erations, DeltaRGF, AAA, and AGA, produced a conditional lethal phenotype, concomitant with severely

69 y, we constructed an inducible mutant with a conditional lethal phenotype.

70 ia coli lac operator/repressor system, had a conditional lethal phenotype.

71 e mutant was constructed and shown to have a conditional lethal phenotype: H7 expression and infectio

72 The recombinant virus, vA32i, has a conditional lethal phenotype: infectious virus formation

73 ading frame can completely suppress the acpS conditional, lethal phenotype upon overexpression of the

74 ere able to rescue the temperature-sensitive conditional-lethal phenotype of VDAC-deficient yeast, wh

75 The mutant exhibited a conditional-lethal phenotype, as cell-to-cell virus spre

76 like a previously described L1 mutant, had a conditional-lethal phenotype: plaque formation and repli

77 ning gene essentiality and creating specific conditional lethal phenotypes.

78 pressed specifically inhibit the growth of a conditional lethal prp38-1 spliceosome assembly mutant i

79 A conditional lethal recombinant vaccinia virus, vA28-HAi,

80 y the construction and characterization of a conditional lethal recombinant virus with an inducible c

81 We constructed a conditional-lethal recombinant vaccinia virus with an in

82 ions identified are three suppressors of the conditional lethal rho allele, rho201.

83 roclivity for copper uptake, we developed a "conditional lethal" screen to identify compounds whose c

84 , as the C. albicans gene can complement the conditional lethal sec65-1 mutation in S. cerevisiae.

85 a monomer, and it was unable to complement a conditional-lethal secA mutant, was inactive for in vitr

86 Moreover, although conditional lethal spc24-2 and spc25-7 cells form a mito

87 of Srp40p, the yeast Nopp140 homologue, in a conditional lethal strain induces the loss of box H/ACA

88 e inner membrane of either htrB null or msbA conditional lethal strains.

89 thus avoiding the problem of constructing a conditional lethal system.

90 t and produce a strong r phenotype, whereas conditional-lethal t alleles produce the classical t phe

91 A conditional lethal, temperature-sensitive mutant in one

92 marily limited to embryos heterozygous for a conditional lethal transgene combination.

93 We generate conditional-lethal (ts) alleles of C. albicans ESS1 and

94 uman HepG2 cDNA library was transformed into conditional-lethal yeast sec7 mutants.

95 Conditional lethal YidC mutants have been isolated to de