ライフサイエンスコーパス: conduction

1 this inter-helical motion accompanies proton conduction.

2 tions and delays both atrial and ventricular conduction.

3 of the pore that enables preferential sodium conduction.

4 l lack of macrophages delay atrioventricular conduction.

5 e functional remyelination, restoring normal conduction.

6 d to quantify nonlinear contributions to the conduction.

7 others identified distinct phases of atrial conduction.

8 indicate that this pinched state impairs ion conduction.

9 uding Cx43, in controlling contractility and conduction.

10 e of trap-limited and grain-boundary-limited conduction.

11 cess to the elementary parameters of carrier conduction.

12 n that has previously been linked to cardiac conduction.

13 mportant for action potential initiation and conduction.

14 bandgap, thus delaying the onset of bipolar conduction.

15 hanisms underlying the history-dependence of conduction.

16 e endothelial dysfunction, and alter cardiac conduction.

17 hese results clarify the basis of CaCC anion conduction.

18 e macrophages in normal and aberrant cardiac conduction.

19 these mice, a compound able to increase axon conduction, 4-aminopyridine-3-methanol, promotes further

20 li lead to a time-dependent reduction in ion conduction, a phenomenon known as C-type inactivation.

21 e membrane, reduces INa and leads to cardiac conduction abnormalities and premature death owing to ar

22 Conduction abnormalities are a common finding after tran

23 s-onset AF preceded by atrial dilatation and conduction abnormalities.

24 The greater the conduction abnormality the greater the discordance of LV

25 pathway for both lipid translocation and ion conduction across the membrane.

26 ated axons, may underlie their dysfunctional conduction akin to muscle weakness in multiple sclerosis

27 ally, we propose that precise fine-tuning of conduction along already-myelinated axons may also be me

28 exert differential roles in action potential conduction along the axonal membrane of nociceptive, unm

29 abnormalities with aberrant atrioventricular conduction and an increased rate of arrhythmia in hetero

30 nes KCNA4 and KCNIP4, involved in electrical conduction and arrythmia, SMOC2, involved in matrix remo

31 lications in gas storage and separation, ion conduction and catalysis.

32 Myocytes are responsible for electrical conduction and contractile force generation, while the o

33 In cardiac fibrosis models exhibiting slow conduction and ectopic activity, block of TGF-beta1 sign

34 Nonuniform conduction and fractionated electrograms were present in

35 kthrough locations and regions of nonuniform conduction and fractionated electrograms.

36 helping to understand properties such as ion conduction and heterogeneous catalysis.

37 properties and independent tunability of ion conduction and mechanical properties, this bioinspired a

38 diographical imaging, we studied whole heart conduction and repolarization patterns during ajmaline c

39 adult height is a marker of altered cardiac conduction and that these relationships may be causal.

40 Topological semimetals are systems in which conduction and valence bands cross each other and the cr

41 motor axons, causing pain, inefficient nerve conduction, and the ectopic migration of oligodendrocyte

42 ty in action potential shape and macroscopic conduction, and the spatial organization of cell-to-cell

43 eful for investigating arrhythmias and other conduction anomalies, and because of their relatively si

44 % tensile strain we report surface-dominated conduction at up to a temperature of 240 K, persisting e

45 est to understanding hydrogen's mechanism of conduction, atomic or pairing structure, as well as the

46 The increased density of states at the conduction band (CB) minimum in the monolayer BiO2-x is

47 model, which predicts that states below the conduction band are responsible for the metastability ch

48 se in band gap is mainly due to lowering the conduction band at K point.

49 bands and a predicted spin splitting at the conduction band edges, the lowest-lying excitons in WX2

50 cter of the S 3s leading to a relatively low conduction band energy at the Gamma point.

51 band maximum (VBM) (-10 to -160 meV) and the conduction band minimum (CBM) (-20 to -70 meV).

52 t time that the frontier orbital energetics (conduction band minimum (CBM) and valence band maximum (

53 A distinct difference in the location of conduction band minimum between Mg2 Si and the isostruct

54 n of Fe dopants changes the character of the conduction band minimum from Ni-oxide in the Ni-only to

55 ount of electrons being transferred from its conduction band minimum to that of In2 O3 over the inter

56 rt cation-cation contacts creates a very low conduction band minimum.

57 tes interact with the extended states of the conduction band of GaAsP host.

58 contributes to the spin polarization of the conduction band of hydrogen-doped ZnCoO.

59 The charge transfer between the conduction band of nAu and pi* continuum of polyaromatic

60 absorption edge appeared at 1.1 eV below the conduction band of SiC.

61 ich is sensitive to the free carriers in the conduction band of the semiconductor substrate.

62 The injected electrons can be stored in the conduction band of TiO2 on an ms-s time scale, and we pr

63 ferromagnetism and spin polarization in the conduction band of ZnCoO.

64 ematically tune the band gap and valence and conduction band positions of metal halide perovskites th

65 ional Hg3Se2I2 a more prominently dispersive conduction band structure and leads to a low electron ef

66 Hg vacancies) has a strong influence on the conduction band structure, which gives the quasi one-dim

67 associated with optical transitions from the conduction band to lower E- and upper E+ valence subband

68 decreasing with increasing energy in the t2g conduction band.

69 the Bi (or N)-related downward shift of the conduction band.

70 ctronic states optically coupled to the host conduction band.

71 sitions between these radical states and the conduction band.

72 ted luminescence is ascribed to decay of the conduction-band electron following transfer of the photo

73 (NCs) involves recombination of delocalized conduction-band electrons with copper-localized holes.

74 possess topologically nontrivial valence and conduction bands that touch at a line near the Fermi lev

75 The spread of the valence and conduction bands, coupled with the narrow HOMO-LUMO gap,

76 bandgap semiconductors with wide valence and conduction bandwidths.

77 decreasing intercellular cleft widths slows conduction because of reduced sodium current driving for

78 ely reproduces both normal and drug-modified conduction behavior.

79 y temperature, including long-range electron conduction between molecules and between microbes and mo

80 autoantibody depletion and with recovery of conduction block and distal motor amplitude suggesting a

81 r these deficits is loss of myelin, creating conduction block at the site of injury.

82 ients had a severe phenotype associated with conduction block or decreased distal motor amplitude.

83 Conduction blocks crossing the core region, but not reac

84 precisely targeted by light to induce local conduction blocks of circular or linear shapes.

85 reveals not only the molecular basis of ion conduction but also the unique architecture of TRPMLs, w

86 ress the molecular basis for this asymmetric conduction by investigating the structure and dynamics o

87 We review building capacity for conduction cardiovascular intervention through strengthe

88 hreshold slope, gate voltage at the onset of conduction, contact resistance and gate capacitance.

89 that height-related differences in electric conduction could be potential mediators of this relation

90 level leads to cardiac dysfunction, such as conduction defect, DCM, and heart failure, remains uncle

91 ntractility and ameliorated intraventricular conduction defects in LmnaH222P/H222P mice, which was as

92 associated with the presence at baseline of conduction defects on the ECG and left ventricular systo

93 hmias, atrial fibrillation, atrioventricular conduction defects, and death by 4 months of age.

94 is associated with total and sudden deaths, conduction defects, left ventricular dysfunction, and su

95 VES and CAP2 murine knockouts caused cardiac conduction defects.

96 usion, the RVOT had the greatest increase in conduction delay (5.4+/-2.8 versus 2.0+/-2.8 versus 1.1+

97 narrow QRS and nonspecific intraventricular conduction delay (NICD) display a relatively limited res

98 At the timescale of a single burst, conduction delay has a non-monotonic relationship with i

99 lore the mechanisms of history-dependence of conduction delay in axons and develop an empirical equat

100 In patients with BrS, conduction delay in RVOT, but not RV or left ventricle,

101 ype I BrS pattern is attributed to degree of conduction delay in the RVOT and not prolongation in rep

102 f minutes, the mean value and variability of conduction delay increase.

103 logy is tightly tuned to minimize wiring and conduction delay of synaptic events.

104 was minimal change in J-ST point elevation, conduction delay, or activation recovery intervals at al

105 al delays, corticothalamic axons can exhibit conduction delays of <2 ms to 40-50 ms.

106 Activity-invariant synaptic transmission and conduction delays were present exclusively in fast condu

107 All three compounds block ion conduction directly by fully or partially occupying the

108 of patients with cardiomyopathy and clinical conduction disease.

109 n the presence of symptomatic bradycardia or conduction disturbance (2D); 3) in patients refractory t

110 e phenotypically affected and showed cardiac conduction disturbance (81%), low left ventricular eject

111 tations had an earlier occurrence of cardiac conduction disturbance and low left ventricular ejection

112 a risk factor for the early onset of cardiac conduction disturbance and the occurrence of atrial arrh

113 s, including dilated cardiomyopathy, cardiac conduction disturbance, atrial fibrillation, and maligna

114 embers was characterized by atrioventricular conduction disturbances (61% and 44%, respectively), sup

115 dictive factors, and clinical association of conduction disturbances after TAVR and propose a strateg

116 ve been associated with a heightened risk of conduction disturbances and permanent pacemaker implanta

117 Cardiac arrhythmias and conduction disturbances are accompanied by structural re

118 ocedural complications, yet the incidence of conduction disturbances has remained relatively high, wi

119 TAVR-related conduction disturbances, mainly new-onset left bundle-br

120 enabling the observed conductivity as proton conduction dominated by extrinsic pathways would be enab

121 RATIONALE: Notch signaling programs cardiac conduction during development, and in the adult ventricl

122 enes for familial sinus and atrioventricular conduction dysfunction are known, and the majority of ca

123 LE: Familial sinus node and atrioventricular conduction dysfunction is a rare disorder that leads to

124 er, implicating a mechanism involving neural conduction efficiency.

125 their complex interactions with 6d and other conduction electron states, has thwarted efforts for ful

126 magnetic moments required for scattering the conduction electrons in the Kondo effect.

127 The conduction electrons occupy a single 2D subband and have

128 nducting materials produces heating of their conduction electrons, followed by relaxation into phonon

129 ong the paramagnetic centers mediated by the conduction electrons.

130 e larger damping due to magnon scattering by conduction electrons.

131 ria after ablation close to main interatrial conduction fascicles (P=0.035).

132 the highest values so far reported in proton conduction for COFs.

133 However, due to volume conduction, FPs may reflect activity in distant neurons

134 tational model representing perturbed signal conduction from myelin.

135 tructural architecture underlying its proton conduction function, we know little about its conformati

136 d Cu2O is governed by grain-boundary-limited conduction (GLC), while after high-temperature annealing

137 It changes the graphene conduction greatly and provides the possibility of reali

138 The mechanism of conduction has been determined using (1)H and (7)Li soli

139 rimental signatures of edge-bound electrical conduction have remained elusive, primarily due to the l

140 able for weak monoacids and the mechanism of conduction have remained unclear.

141 y increasing the contribution from transient conduction heat transfer.

142 ocol, this novel inhibitor improved neuronal conduction, highlighting its potential for alleviating s

143 d normal large fibre sensory and motor nerve conduction; however, skin biopsy showed a significant de

144 to describe the dynamics of low dimensional conduction in a larger class of superionic conductors.

145 y thus reveals the structural basis of anion conduction in a TMEM16 channel and it defines the founda

146 TTX-s and TTX-r channels to action potential conduction in different axonal compartments, we investig

147 V1.8 is the primary isoform underlying TTX-r conduction in distal axons of somatosensory C-fibers.

148 ring plays a significant role in microscopic conduction in GNRs with different edge structures.

149 MC exhibits a low energy barrier for proton conduction in IT-SOFCs.

150 imental studies to study normal and abnormal conduction in multidimensional excitable tissue, and the

151 r are essential regions for action potential conduction in myelinated fibers.

152 STO, the anisotropy of interfacial electron conduction in relationship to the domain wall and its di

153 ons are conducted to investigate phonon heat conduction in SLs and RMLs with lattice imperfections.

154 -dominated to coherent-phonon-dominated heat conduction in SLs when the number of interface increases

155 rovide reference data for understanding heat conduction in the Earth's deep interior.

156 wing and decreased heterogeneity of electric conduction in the peri-infarct zone than wild-type mice.

157 (Nav) and thus underpin rapid nerve impulse conduction in the vertebrate nervous system [1].

158 effective in blocking atrioventricular nodal conduction in these patients.

159 These results indicate that asymmetric conduction in WT M2 is due to W41 inhibition of C-termin

160 iptional regulators of sinus node and atrial conduction, including Nkx2-5 (NK2 homeobox 5), Tbx3, and

161 operties, particularly long-range electrical conduction, into the basic topological motif of DNA rema

162 Ion conduction involves two states per cycle, the late M- (M

163 Slowed atrial conduction is a mechanism of AF in MetS.

164 that (in such a many-body resonance) finite conduction is achieved from a charge frozen by Coulomb i

165 ) channels and the prokaryotic KcsA channel, conduction is believed to result from opening of an intr

166 they combine to control firing patterns and conduction is not well understood.

167 measured as recovery of affected optic nerve conduction latency using full-field visual evoked potent

168 ocal to the wrist (i.e. median sensory nerve conduction latency) and in the brain (i.e. digit 2/3 cor

169 altitude of 700 kilometres, above which heat conduction maintains an isothermal atmosphere.

170 d; however, the nature of carriers and their conduction mechanism at the atomic scale remain unclear.

171 II) release is the rate-limiting step in the conduction mechanism during recrystallization.

172 titative and analytical investigation on the conduction mechanism in p-type cuprous oxide (Cu2O) thin

173 Here, we posit a conduction mechanism relying on field-modification effec

174 y affects the dielectric properties, leakage conduction mechanisms, and the resistive hysteresis of t

175 excited oscillatory resistance using a multi-conduction model in order to examine the interplay betwe

176 e limit for life, 122 degrees C, with a heat conduction model that predicts a potential depth limit f

177 r from phonon-, to charged-impurity, limited conduction occurs once the concentration of gate-induced

178 Axons are neuronal processes specialized for conduction of action potentials (APs).

179 rvous system (CNS) is required for saltatory conduction of action potentials along neuronal axons.

180 nnels are responsible for the initiation and conduction of action potentials within primary afferents

181 n potentials occurs, allowing fast saltatory conduction of action potentials.

182 h effective depolarization may promote rapid conduction of contraction along lymphatic muscle during

183 depolarization of LECs may promote the rapid conduction of contraction waves along lymphatic muscle d

184 Although myocardial conduction of excitation has been widely described, the

185 ain by re-entrant scroll waves, fibrillatory conduction of multiple wavelets or rapid focal activity.

186 insulative nature is the basis for saltatory conduction of nerve impulses.

187 croscopic studies and their effects upon the conduction of photovoltaic current still remain elusive.

188 SCN5A lead to defects in the generation and conduction of the cardiac electrical impulse and are ass

189 solvent-accessible His-27 facilitates proton conduction of the channel by increasing the proton disso

190 e to the atrial wall can change the electric conduction of the left atrium, potentially leading to at

191 mapping of perfused hearts confirmed slowed conduction on atria and ventricles of MetS-VLDL mice.

192 ever, the surface state dominates electrical conduction only below T( *) approximately 4 K, limiting

193 der low external pH while W41 ensures proton conduction only from the N terminus to the C terminus an

194 000,000 recorded APs, we did not observe any conduction or branch-point failures.

195 Electronic conduction or charge transport through single molecules

196 new targets for drugs that may modify atrial conduction or treat atrial arrhythmias.

197 TM1 helices form a bottleneck along the ion conduction pathway and serve as the selectivity filter o

198 rely degraded by the presence of a parasitic conduction pathway at the nitride-substrate interface wh

199 heights calculated for critical steps in the conduction pathway indicate that this pinched state impa

200 hell, Tube(wedge)2 allows the semiconducting conduction pathway to be modulated solely by surface fun

201 es creates a 'polar track' demarking the ion-conduction pathway.

202 tions on the vulnerability to unidirectional conduction patterns and dynamics of re-entrant excitatio

203 Improvements in peripheral nerve conduction positively correlated with cytokine-induced i

204 p < 0.001) and reduced both atrioventricular conduction (PR segment-p = 0.02; PR interval-p = 0.02) a

205 ynamical structures that govern the fast ion conduction process in fluorites.

206 cell current flow that is responsible for AP conduction (propagation) within the mammalian myocardium

207 ase in heart rate and atrioventricular nodal conduction properties and might be critical for vagal at

208 remodeling that significantly change axonal conduction properties are most likely to occur over time

209 ors, have demonstrated dual electronic/ionic conduction properties.

210 To understand how His-27 affects the proton conduction property of BM2, we have used solid-state NMR

211 hotovoltaic current originates from its high conduction rather than the internal electric field.

212 Ablation of the areas of slow conduction resulted in a high acute success.

213 inter-atomic spacing the transition to heat conduction should take place.

214 ve terminals, thermal hypoalgesia, and nerve conduction slowing in diverse rodent models of diabetes.

215 Consistent with conduction slowing, genes encoding molecular determinant

216 n the unmyelinated axons of hippocampus, the conduction speed of APs depends crucially on axon diamet

217 boutons, followed by a sustained increase in conduction speed that accompanies the axon shaft widenin

218 namics predicted bidirectional effects on AP conduction speed.

219 ination, quantitative sensory testing, nerve conduction studies and skin biopsy for intraepidermal ne

220 Nerve conduction studies assessing median nerve sensory latenc

221 antitative sensory hand function and sensory conduction studies by near-nerve technique, including ta

222 To date, most water conduction studies on AQP0 were performed on protein exp

223 Nerve conduction studies showed normal large fibre sensory and

224 In all cases, large fibre nerve conduction studies were normal.

225 Clinical examinations, nerve conduction studies, and vibratory perception thresholds

226 cytes, and their perturbation alters cardiac conduction, suggesting that pharmacological manipulation

227 m recordings in Mybphl mice revealed cardiac conduction system abnormalities with aberrant atrioventr

228 imensional relationships between the cardiac conduction system and surrounding structures, we provide

229 r role in the development of the ventricular conduction system and that electrical propagation across

230 findings of reduced ventricular function and conduction system defects in Mybphl mice support that MY

231 y with dilated cardiomyopathy and associated conduction system disease in whom prior clinical cardiac

232 vents in the absence of skeletal myopathy or conduction system disorders.

233 c death, and absence of skeletal myopathy or conduction system disorders.

234 rt, calcification of cardiac muscle leads to conduction system disturbances and is one of the most co

235 3-dimensional representations of the cardiac conduction system within the intact human heart.

236 , radiation can damage the heart valves, the conduction system, and pericardium, which may take years

237 ther AF variants have diverse effects on the conduction system, ranging from none to extensive.

238 t of macrophages residing within the cardiac conduction system, which orchestrates cardiac rhythm.

239 d in epidermal keratinocytes and the cardiac conduction system.

240 iomyocytes known collectively as the cardiac conduction system.

241 ting the critical role of Slc26a6 in cardiac conduction system.

242 of spontaneous depolarization and electrical conduction that may be involved in cardiac arrhythmia.

243 elin can, in turn, affect several aspects of conduction, the concept has emerged that activity-regula

244 ctive Fe(II) release coupled 1:1 by electron conduction through crystallites.

245 pervading biocompatible interface for charge conduction through highly absorbing protein multilayers

246 at cardiac macrophages facilitate electrical conduction through the distal atrioventricular node, whe

247 n potential waveforms and uniform electrical conduction throughout the patch.

248 Thalamocortical conduction times are short, but layer 6 corticothalamic

249 We show that axonal conduction times are strongly related to multiple visual

250 Here, we investigate (1) how axonal conduction times of corticogeniculate (CG) neurons are r

251 CG conduction times were also significantly related to visu

252 othalamic axons display an enormous range of conduction times, some exceeding 40-50 ms.

253 ing the spectrum of corticogeniculate axonal conduction times.

254 visual processing across the spectrum of CG conduction times.

255 iform across the broad spectrum of CG axonal conduction times.SIGNIFICANCE STATEMENT Corticothalamic

256 , GLC becomes insignificant and trap-limited conduction (TLC) dominates.

257 borate to generate SWs in ICC-IM followed by conduction to adjacent SMCs where phasic calcium entry t

258 The activation energies for Li-ion conduction traversing the grain boundaries are consisten

259 sided contact, we measure enhanced radiative conduction up to 16 times higher than the blackbody limi

260 xcitation of trapped carriers back up to the conduction/valence bands.

261 25 degrees C and 40% RH, a very high proton conduction value for low humidity and moderate temperatu

262 ysis of pelletized powders revealed a proton conduction value of over 10(-3) S cm(-1) at 25 degrees C

263 ents with E90K and N98S had upper limb motor conduction velocities <38 m/s.

264 al, P=0.0005; left atrial, P=0.0001), slower conduction velocities (right atrial, P=0.02; left atrial

265 rving spatially uniform properties with high conduction velocities and contractile stresses.

266 Conduction velocities were higher and action potential d

267 atrial and left atrial voltage distribution, conduction velocities, and electrogram characteristics w

268 , bipolar EGM amplitude (0.08+/-0.11 mV) and conduction velocity (0.27+/-0.19 m/s) were lower than th

269 Effects of mutations on AP duration (APD), conduction velocity (CV), effective refractory period (E

270 onal loss, which underlie slowed motor nerve conduction velocity (MNCV) and reduced compound muscle a

271 n either behaviors or acute changes in nerve conduction velocity (NCV) and amplitude, but greater und

272 Such dysregulations led to defects in conduction velocity and motor and sensory functions that

273 Axonal conduction velocity can change substantially during ongo

274 activity levels, and axonal myelination and conduction velocity exhibited no adaptations.

275 KEY POINTS: Changes in nerve conduction velocity following an impulse (i.e. velocity

276 ervention and training-induced changes in MU conduction velocity had an effect size of 2.1 (tracked M

277 in addition to decreased heart rate, atrial conduction velocity is persistently slower than control.

278 Conduction velocity remained constant at chemically incr

279 By analyzing the effects of conduction velocity restitution, cellular dynamics, elec

280 er EGM amplitude with a significantly slower conduction velocity than the surrounding parts of the ci

281 itigate the frequency-dependent decreases in conduction velocity typical of C-fiber axons.SIGNIFICANC

282 Simultaneous optical Vm mapping showed that conduction velocity, action potential duration, and dVm/

283 width helps to control transmitter release, conduction velocity, and firing patterns and understandi

284 es encoding molecular determinants of atrial conduction velocity, including Scn5a (Nav1.5) and Gja5 (

285 array platform and thereby the estimation of conduction velocity, which gradually increased during th

286 in a progressive slowing of action potential conduction velocity, which manifests as a progressive in

287 ity mechanism for dynamically fine-tuning AP conduction velocity, which potentially has wide implicat

288 ) showed an age-dependent increase of axonal conduction velocity, which was positively correlated wit

289 s were analyzed for amplitude, duration, and conduction velocity.

290 daptations in axon myelination for increased conduction velocity.

291 anomaly in non-equilibrium transport suggest conduction via spin-polarized states in the presence of

292 Slowed cardiac conduction was associated with significant atrial and ve

293 l evaluation of both sensory and motor nerve conduction was performed.

294 Fibrillatory conduction was suggested as a decrease in the frequency

295 essing macrophages improves atrioventricular conduction, whereas conditional deletion of connexin 43

296 ith the P wave were linked to overall atrial conduction, whereas others identified distinct phases of

297 This defect is associated with slowed nerve conduction, which could contribute to behavioral deficit

298 riments, revealing a phase of slowed down AP conduction, which is linked to the transient enlargement

299 Se2 display tunable ambipolar charge carrier conduction with a high electron field-effect mobility of

300 e structure that reversibly switches thermal conduction with high ON/OFF ratios and at high speed.