ライフサイエンスコーパス: congener

1 BDE-47 was the predominant congener.

2 plex but radical chain initiation for the Ru congener.

3 l T4 was inversely associated with each PBDE congener.

4 s previously described alkyne-functionalized congener.

5 ve properties with respect to its all-carbon congener.

6 and their drastically more reactive Au(III) congeners.

7 nds previously reported for less chlorinated congeners.

8 to improve the extraction recovery of 19 PCB congeners.

9 utionarily naive North American and European congeners.

10 ns were collected and analyzed for 17 PCDD/F congeners.

11 ew, including seven 11-deoxy-16R-hydroxy-PTM congeners.

12 stent but variable pattern of diCB to nonaCB congeners.

13 s give higher yields than electron deficient congeners.

14 e samples to detect the low level of the PCB congeners.

15 ring deoxycalyciphylline B and its synthetic congeners.

16 e indirect regulation by GPCRs in eukaryotic congeners.

17 ent reactivity with respect to their organic congeners.

18 and perfluorohexanoate were the predominant congeners.

19 ajor dominating and most frequently detected congeners.

20 quartile range, 7.6-50.2)) or for individual congeners.

21 can ambient conditions and lower-chlorinated congeners.

22 arly for the emerging and low molecular mass congeners.

23 ing biotransformation from higher brominated congeners.

24 ls performed better for p,p'-DDT/E than PBDE congeners.

25 iduals of Juniperus microsperma and its five congeners.

26 ns of 11 OC pesticide metabolites and 34 PCB congeners.

27 00 and 2010, and discuss the fate of six PCB congeners.

28 benes and its one- and two-electron oxidized congeners.

29 is especially relevant for highly brominated congeners.

30 tensioned differently compared to phosphorus congeners.

31 a variety of non-2,3,7,8 substituted PCDD/F congeners.

32 ty of different (lighter versus heavier) PCB congeners.

33 hybridization between octoploid and diploid congeners.

34 affins) technical mixture that contains 7820 congeners.

35 nt based on toxic equivalency of dioxin-like congeners.

36 as-yet undetermined biosynthesis of several congeners.

37 p,p'-DDE, HCB, beta-HCH, dicofol, and PCBs (congeners -138, -153, and -180) were predominantly assoc

38 emicals for predicting risk overall were PCB congener 180 and propoxur.

39 ding 12 polybrominated diphenyl ether (PBDE) congeners, 19 other brominated FRs, 11 phosphorus FRs (P

40 y, C-8a-hydroxymethyl-1-deoxycastanospermine congeners 1a, 2a, 3a and their 3-oxo analogs 1b, 2b, and

41 In contrast, the cellular effects of congener 21a, which inhibited Clk1 only weakly, were sub

42 d maternal serum concentrations of DDT, PBDE congeners 28 and 183, and paternal serum concentrations

43 tion and fragmentation behavior of 14 PBDEs (congeners 28, 47, 66, 85, 99, 100, 153, 154, 183, 184, 1

44 fficiencies varied from 0.32 to 0.50 for BDE congeners 28, 47, 99, 100, 153, and 154.

45 3beta) via the full-length receptor] and its congener 3-(1H-imidazol-4-yl)propyl-(4-iodophenyl)-methy

46 BDE congeners 47, 99, and 100 were highly correlated and sum

47 2, H5N1, and H7N9), although the phosphonate congener 6a is unexpectedly less active than peramivir.

48 organic pollutants (POPs), including 21 PCB congeners, 8 PBDE congeners, and 21 organochlorine pesti

49 olites are formed from axially prochiral PCB congeners, a fact that should be considered when studyin

50 d by a higher proportion of 153, 138 and 180 congeners, according to their high resistance to metabol

51 While less brominated congeners achieved faster dermal penetration, higher PBD

52 rated briefly every 2 min, while none of the congeners achieved more than 50% of equilibrium in stati

53 reoisomers and evaluated alongside their 4'' congeners against cultured malaria parasites and in a mu

54 found a patchy distribution pattern of both congeners along a stretch of 100 km, whereby one species

55 BDE-47 was the most abundant congener among the 14 PBDEs, followed by BDE-99.

56 The distribution of congeners among different species did not show significa

57 Concentrations of 11 PCB congeners and 2 OCPs measured in banked second-trimester

58 latile, non-dioxin-like, low-chlorinated PCB congeners and HCB.

59 ination exists in sub-social closely related congeners and is likely a selective force in the sub-soc

60 iate linear regression analyses between PBDE congeners and their sum (SigmaPBDEs) and outcomes.

61 Boston, Massachusetts, for analysis of PBDE congeners and THs.

62 nts showed good agreement both in individual congeners and toxic equivalence factors (TEQs).

63 s (POPs), including 21 PCB congeners, 8 PBDE congeners, and 21 organochlorine pesticides.

64 We analyzed for 209 PCB congeners, and 85 peaks are reported (other congeners ei

65 Stephacidin A and its congeners are a collection of secondary metabolites that

66 The concentrations of both PCB congeners are affected by the different transport regime

67 Because low-chlorinated congeners are more volatile, these observations suggest

68 We hypothesized that additional non-Aroclor congeners are present in serum.

69 However, these "congeners" are not derived from enantiodivergent biosynt

70 N), and polybrominated diphenyl ether (PBDE) congeners as well as some pesticides (e.g., permethrin)

71 on of 20 anabaenopeptins, including 13 novel congeners, as well as their pronounced structure-activit

72 groups due to the limitations of commercial congener availability.

73 um concentrations of the most prevalent PBDE congeners (BDE-28, BDE-47, BDE-99, BDE-100, and BDE-153)

74 PBDE congeners (BDE-47, -99, -153, -154, and -209) were deter

75 l release of PBDEs and serum levels of three congeners (BDE-47, BDE-100, and BDE-153).

76 ween breast milk concentrations of five PBDE congeners-BDEs 28, 47, 99, 100, and 153-and child's weig

77 Mononickel congeners bearing related N-donor chelates (2-iminopyrid

78 benzoate esters, including its ring expanded congener benzotripyranone (BTP).

79 , we demonstrate how an understanding of PCB congener bioaccumulation dynamics provides multiple dire

80 fine sands) showed greater influence on PAE congener bioconcentration factors compared to PAE molecu

81 is well-known phenomenon of enantiodivergent congener biosynthesis within the same producing organism

82 hese experiments showed that PAL1045 and its congeners bound with different affinities (ranging from

83 y of the selected aptamer to the two similar congeners, BTX-2 and -3, whereas no cross reactivity to

84 Nucleophilic dechlorination of all 209 PCBs congeners by ethylene glycol anion has been studied theo

85 ts that exceptionally large individuals of a congener (C. aurita) and extinct giant frogs (Beelzebufo

86 synthesis can be used in the preparation of congener cavitands with different properties and applica

87 ak concentration magnitudes, and in the PCBi congeners compositions.

88 riable linear regression models, PBB and PCB congener concentrations, on both the volume (nanogram/mi

89 tions of 101 polychlorinated biphenyl (PCBs) congeners, congener groups and three chlorinated pestici

90 Peptide congeners containing norvaline, phenylalanine and tyrosi

91 s deposition of BDE-47, with less brominated congeners contributing to Sault Ste.

92 n zooplankter Daphnia lumholtzi and a native congener Daphnia pulex in ambient temperature environmen

93 Fortunately, all PCDD/Fs congeners decomposed well over VOX-MnOX-CuOX/TiO2-CNTs.

94 oncentration (log10), but not other pentaBDE congeners, demonstrated inverse associations with BMI at

95 lationship between focal species density and congener density, while focal species body size was nega

96 species body size was negatively related to congener density.

97 lective GAK inhibitors, with the most potent congeners displaying low nanomolar binding affinity for

98 ally distant sites and detected 232 azaarene congeners distributed in eight homologous series, includ

99 dentify the trends of 2,3,7,8-Cl PCDD & PCDF congener distributions, toxic equivalents (TEQ), and PCD

100 asis of the chemistry developed, the dimeric congener dixiamycin C has been synthesized for the first

101 oxic effects on tern eggs of PCB dioxin-like congener (DLC) exposures, we extrapolated published labo

102 re favorable to those for their homometallic congeners, due to threefold-to-twofold symmetry reductio

103 For individual lower-chlorinated congeners (e.g., PCBs 40+41+71, 52), inhalation exposure

104 congeners, and 85 peaks are reported (other congeners either coeluted or were near or less than the

105 the exact mechanism through which palytoxin congeners exert their inhalatory toxicity is still unkno

106 s a step toward demonstrating that palytoxin congeners exert toxic effects through inhalation both in

107 ncement over the previously reported Ir(III) congeners featuring carboranyl-containing ligands in whi

108 cm(-2).yr(-1)) and the predominance of heavy congeners for most of the time period are consistent wit

109 )-1 and -2 (APC-1 and APC-2, a water-soluble congener) for the chemoselective visualization of Cu(II)

110 BDE-47 and BDE-99 are the predominant PBDE congeners found in Chinook salmon collected from the Pac

111 ort by salmon, we compared 58 PCB and 6 PBDE congeners found in spawning salmon directly to those in

112 g domain" fragment A-I or its C26-des-methyl congener, fragment A-II.

113 s from TeDB-DiPhOBz, and Br(6)- to Br(8)-BDE congeners from BDE-209), formed after 21 days of natural

114 nd four polybrominated diphenyl ether (PBDE) congeners from maternal and/or child levels 9 years afte

115 and BDE-209 (i.e Br(8)- to Br(11)-PB-DiPhOBz congeners from TeDB-DiPhOBz, and Br(6)- to Br(8)-BDE con

116 and the distribution of the seven indicator congeners (further referred to as PCBi) as an indicator

117 toxicity of XWL-1-48 is more potent than its congener GL331 and the IC50 values are from 0.34 +/- 0.2

118 grase inhibitor raltegravir, and a GRL-09510 congener (GRL-09610), no variants highly resistant again

119 njection, that also yields information about congener group pattern.

120 umber of chlorines (m) are referred to as a "congener group" CnClm.

121 When applying Model 2 to PCB congener groups and individual pesticides, there were si

122 1 polychlorinated biphenyl (PCBs) congeners, congener groups and three chlorinated pesticides [dichlo

123 entrations of polychlorinated biphenyl (PCB) congener groups and three chlorinated pesticides in a Na

124 The profiles of congener groups varied among different sites.

125 e series, and the most abundant nonalkylated congeners groups (C13H9N, C15H9N, C17H11N, C19H11N, and

126 Salmon exposed to either congener had reduced survival during challenge with the

127 Summed concentrations of the 21 PCB congeners had a national weighted mean of 32.7 mug/kg an

128 yntheses of (+)-haplocidine and its N1-amide congener (+)-haplocine.

129 e reported structure of baulamycin A and its congeners has been developed for the first time.

130 low oxidation state reagents of the lighter congeners have allowed for the generation of complexes c

131 site, Zeppelin at Spitsbergen, different PCB congeners have been continuously measured for more than

132 n, not least because no naturally tool-using congeners have yet been identified that would enable inf

133 988-1989, six polychlorinated biphenyl (PCB) congeners, hexachlorobenzene (HCB), and dichlorodiphenyl

134 Among the non- and mono-ortho congeners, highest to lowest quartile of dioxin TEQs was

135 discrepancy in structures predicted for C99 congener homodimers in membrane and micelle environments

136 to the numbers of congeners in the diets, or congener hydrophobicity, but was greater in foods with h

137 carbo-cyclohexadienes, and to "pro-aromatic" congeners, i.e. rigid sigma,pi-macrocyclic carbo-quinoid

138 imilar antimicrobial activity to other known congeners, illustrating that in vitro biosynthesis is a

139 Aroclor 1270 and 1271, was the most abundant congener in 10 of the samples but lower in others.

140 quantification of every isotope diluted PCB congener in a single gas chromatography-tandem mass spec

141 BDE-209 is the dominant congener in most of the pan-Arctic areas except for the

142 The dominant congener in sediment, DecaBDE component BDE-209, showed

143 complexity was correlated with the number of congeners in a species' range, suggesting that perfume e

144 The rank order potency of the EROD-active congeners in all three species was as follows: TCDD>dibe

145 ominated by PCB 28/31 and higher-chlorinated congeners in both groups reflecting rapid metabolism of

146 A simple approach to determine 19 PCB congeners in catfish tissue was presented.

147 Depletion and enhancement of PCB congeners in factors, relative to Aroclor 1254, suggeste

148 .10, 3.02), and for highest deciles of other congeners in secondary analyses.

149 dechlorinated to nontoxic non-2,3,7,8 PCDD/F congeners in sewers and landfills as well as in the sedi

150 with all 209 polychlorinated biphenyl (PCB) congeners in surface water, treated and untreated wastew

151 is breeding system must therefore manage the congeners in tandem which will also maintain the potenti

152 Rate constants for temporal decline of PCB congeners in tern eggs varied inversely with log10KOW (n

153 not significantly related to the numbers of congeners in the diets, or congener hydrophobicity, but

154 We identify a short total synthesis of congeners in the reverse-prenylated indole alkaloid fami

155 opriate; however, inclusion of different PCB congeners in various iPCB schemes makes it challenging t

156 oth non-cancer and carcinogenic risk for PAE congeners in wheat were higher than those in maize, sugg

157 However, both congeners increased the in vitro production of superoxid

158 ound that omeprazole and its closely related congeners inhibited melanogenesis at micromolar concentr

159 orPCB based on a more detailed analysis (50+ congeners) is also overall a good approach for assessing

160 Comparing AGN 211377 with a close structural congener lacking EP1 antagonism (AGN 197727), AGN 197727

161 investigated the bioaccumulation of three MC congeners (-LR, -RR and -YR) in the chironomid larvae of

162 we report the prevalence of non-Aroclor PCB congeners (</=0.20 wt % in Aroclor) in human serum colle

163 n and characterization of additional natural congeners, mandelalides E-L (5-12), and the supply of sy

164 g a signal comparable to that from the azido congener, ManNAz.

165 r the synthesis of more structurally complex congeners may be a general approach to obtain limonoids

166 one-electron oxidation to the mixed-valence congener [(Me3TPyA)2Fe2(L)](3+), where X-ray diffraction

167 ayed cross-reactivity with seven microcystin congeners (microcystin-leucine-arginine (MC-LR) 100%, mi

168 and spiked with a standard solution of a PCB congener mixture.

169 Likewise, concentrations of BDE-71 -a congener not present in any PBDE commercial mixture- inc

170 lar DNA binding and click reactivity of both congeners observed by fluorescent labeling.

171 on cascade efficiently converted an oxidized congener of akuammicine into the complex, hexacyclic arc

172 Nitroxyl (HNO), a redox congener of nitric oxide (NO.), is a novel regulator of

173 into the cyclotrisilene scaffold, yielding a congener of the cyclobutene anion with considerable ally

174 on pathway for bacitracin A, the most potent congener of the mixture.

175 The iridium congener of the optimized cobalt catalyst, 6-(H)2BPin, w

176 tent CREB inhibitors, a series of structural congeners of 3a was designed and synthesized.

177 the synthesis of the first pnictogen-silicon congeners of benzene, the triarsa- and the triphospha-tr

178 he synthesis of non-natural ethyl and benzyl congeners of deoxyamphimedine and amphimedine.

179 les derived from expanded porphyrins, larger congeners of naturally occurring tetrapyrrole macrocycle

180 th Palythoa spp. and Ostreopsis spp. contain congeners of palytoxin, a highly potent toxin whose inha

181 ned the differences in levels of several POP congeners of potential relevance to human health.

182 -diphenylamine (C9C9) were the most dominant congeners of SDPAs, with concentrations up to 191 ng/g (

183 e the performance of catalysts, in which 130 congeners of tetra- to octapolychlorinated dibenzo-p-dio

184 temperature along with the silicon pnictogen congeners of the cyclobutadiene, [(PhC(NtBu)2)2Si2E2] (E

185 The latter are electron-deficient congeners of the widely utilized N,N'-disubstituted 4,4'

186 to the discovery of sulfur-containing polar congeners of thiotetronic acid (TA) in drinking water fr

187 study we report a route to the more complex congeners of this class of alkaloids exploiting the dias

188 dyes for use in liquid dye lasers, three new congeners of widely used laser dye, PM567, were synthesi

189 but for the d(0) f(0) Y and La and 4f(3) Nd congeners only MIC-->M sigma-bonding is found.

190 markable structural diversity of matlystatin congeners originates from the activity of a decarboxylas

191 luding the partial substrate PAL1045 and its congeners PAL287 and PAL1046.

192 09 decreases with depth, the less-brominated congeners, particularly BDE-47 and BDE-99, increase down

193 ASD risk was elevated for a number of PCB congeners, particularly for the highest vs. lowest quart

194 For stream-resident fish, POP congener pattern was influenced by the presence of salmo

195 Congener patterns also changed, indicating a preferentia

196 Here, PBDE concentrations, congener patterns and inventories are presented for the

197 Congener patterns are similar among cores and indicate d

198 l-water partition coefficient), shifting egg congener patterns away from those characterizing NBH sed

199 or example, sturgeon and whitefish exhibited congener patterns consistent with Aroclor weathering, su

200 ish can alter polychlorinated biphenyl (PCB) congener patterns in fish, but these patterns have never

201 In this work, PCB congener patterns in freshwater fish were examined with

202 Similarity in congener patterns indicated that salmon are a source of

203 Congener patterns of mottled sculpin differed from those

204 imensional scaling (NMDS), we found that POP congener patterns of Pacific salmon varied among regions

205 m fish exposed to salmon spawners would have congener patterns similar to those of salmon, the presum

206 samples demonstrated almost identical PCDD/F congener patterns.

207 -month infant concentration of the prevalent congener PCB-153 was 113 ng/g lipid [interquartile range

208 ated diphenyl ethers (PBDEs), depends on the congeners' physicochemical properties, environmental con

209 Other than their established short-chain congeners, polycondensates based on long-chain difunctio

210 North America, where penta-BDE and tetra-BDE congeners predominate.

211 Congener profiles of five tissue types were dominated by

212 The 2,3,7,8-Cl congener profiles showed slight differences among sample

213 Congener profiles were similar within each sampling loca

214 tics with the more electron-rich naphthalene congeners provided an efficient means to complete the fi

215 rations of summation operatorPCBs (sum of 85 congeners) ranged from 1.52 to 22.4 ng L(-1).

216 nected lakes can influence MC production and congener ratios, we incubated dialysis bags containing p

217 propose that polychlorinated biphenyl (PCB) congeners represent an ideal tracer to quantify in situ

218 of Lake Annecy, enriched in relatively heavy congeners, reveals a contamination by the neighboring La

219 While for lower-chlorinated PCB congeners revolatilization is important, for higher-chlo

220 rbonyl substrate was developed to access the congener rhodomyrtosone B, and oxygenation of the same m

221 fensin 2 [hBD-2]), or the platelet kinocidin congener RP-1.

222 ic nematode Steinernema carpocapsae and four congeners (S. scapterisci, S. monticolum, S. feltiae, an

223 the class-specific SPDMS(L) and a particular congener's entropy of fusion, melting point, and aqueous

224 eatened endemic tree that co-occurs with its congener, S. admonitor.

225 haematobium are very similar to those of its congener, S. mansoni, offering the prospect of designing

226 > PCB, although this affinity was site- and congener-selective.

227 nt SB12036 that accumulated nine PTM and PTN congeners, seven of which were new, including seven 11-d

228 Findings for specific PCB congeners showed a significant inverse association betwe

229 even 2,3,7,8 Cl-substituted PCDD and 10 PCDF congeners showed summation operatorPCDD7 ranging from 22

230 al of S. indicus and its younger and similar congener Sivapithecus sivalensis also supports reconstru

231 against active samplers, yielding an average congener specific concentration method ratio (active/pas

232 thering and degradation, while detailed full congener specific measurements can be time-consuming and

233 Congener-specific analysis showed 1.5-fold higher summat

234 rrelations (Pearson's, alpha = 0.05) between congener-specific concentrations in feces and serum were

235 In the present study, congener-specific estimates of net PBDE assimilation eff

236 We assessed congener-specific inhalation and dietary exposure for 78

237 We performed a congener-specific mixture risk assessment (MRA) of human

238 Congener-specific PCB inhalation exposure was modeled us

239 ed the Hazard Index (HI) method by using BDE congener-specific reference doses for neurodevelopmental

240 A series of congeners structurally related to pritelivir, N-[5-(amin

241 the two sites was inversely correlated with congeners' subcooled liquid vapor pressure, in support o

242 tes, typically derived from dioxygen and its congeners such as hydrogen peroxide.

243 new iPCB schemes in estimating total of PCB congeners ( summation operatorPCB) and dioxin-like PCB t

244 mido)triiron(II) 3 and tri(methoxo)triiron 4 congeners support our assignment of the reduction produc

245 Since PCDD/F congeners that are substituted in the lateral 2, 3, 7, a

246 acutely toxic to avian embryos, while the 10 congeners that did not produce an EROD response caused l

247 ubset of 2-aminopyrimidines yielding several congeners that elicited alpha7 activation with EC50 valu

248 Levels of 10 congeners that interfere with the cellular defense prote

249 Regarding congeners, the association was clearer with BDE-99, with

250 ve purification due to the presence of other congeners, the concentration and the isotopic enrichment

251 ization is important, for higher-chlorinated congeners, the main processes are storage in glacier ice

252 Thorough investigation of the Dy(III) congener through both ac susceptibility and dc magnetic

253 red along with numerous unnatural oligomeric congeners to provide rapid access to discrete collection

254 Emissions of 2,3,7,8-TCDD, the most toxic congener [toxicity equivalence factor (TEF) = 1.0], incr

255 may regulate microcystin (MC) production and congener type.

256 initial one-electron oxidation, the heavier congener undergoes C-H bond cyclometalation and ultimate

257 The fish were exposed to one to eight PBDE congeners up to 1500 ng total PBDEs/g food.

258 1, 5.40)] but the OR for the non-dioxin-like congeners was [OR = 5.01 (95% CI: 1.76, 14.24)].

259 A list of 70 non-Aroclor PCB congeners was determined by measurement of original Aroc

260 The analysis of 15 PBDE congeners was performed in an accredited testing laborat

261 Among various urushiol congeners, we identified diunsaturated pentadecylcatecho

262 This compound and its non-S-oxygenated congener were fully characterized, and their electronic

263 The predominant congeners were 6:8 PFPIA (cormorants and pike) and 6:6 P

264 The most potent congeners were a l-aspartic acid diisoamyl ester phenoxy

265 orption and degradation behaviors of PCDD/Fs congeners were also investigated.

266 Both congeners were also positively associated with maternal

267 The most abundant congeners were BDE-47 (average proportion 42%), -99 (8.4

268 analyses, inverse associations with several congeners were found for ASD relative to GP (e.g., quart

269 Geometric mean levels of several PCB congeners were higher in the ASD group than in the ID an

270 erum concentrations of four PBB and four PCB congeners were measured at least once in 753 adults, inc

271 he biogeochemical controls on PBDEs, 12 PBDE congeners were measured in air, water, sediment and pore

272 r and Tobit regression, log-transformed PBDE congeners were modeled as a function of child characteri

273 artiles of summation operatorPBDEs and 4 BDE congeners were not associated with risk of thyroid cance

274 ncentrations of the strongly hydrophobic PCB congeners were overestimated by up to an order of magnit

275 Around 100 PCB congeners were quantified in the two sampling polymers,

276 PCB congeners were quantified via EPA Method 1668 in fillet

277 Levels of both higher and lower chlorinated congeners were reduced throughout the sediment column in

278 -CNTs, while high chlorination level PCDD/Fs congeners were removed well over VOX-CuOX/TiO2-CNTs.

279 g atmosphere, low chlorination level PCDD/Fs congeners were removed well over VOX-MnOX/TiO2-CNTs, whi

280 PCB congeners were statistically significantly associated wi

281 Levels of TICs, and their individual congeners, were strongly associated with the overall POP

282 fer ratios were observed for most of the PCB congeners when visceral fat was used.

283 (B))6 host as compared to its Zn(II)8(L(A))6 congener, whereas the Fe(II)8(L(B))6 host maintained a s

284 Congeners, which are highly resistant to degradation, su

285 in the selective enrichment of recalcitrant congeners while other, less persistent compounds of tech

286 etric mean concentrations of five of the six congeners with >/=55% of samples above the limit of dete

287 ariable chain length and chlorination level; congeners with a fixed chain length (n) and number of ch

288 higher than the highest PCB BMF observed for congeners with a log KOW of >7.

289 hereas A. protuberus and A. amoenus produced congeners with a syn-bicyclo[2.2.2]diazaoctane core.

290 Achromobacter xylosoxidans Q19 oxidized PQS congeners with alkyl chains ranging from C1 to C5 and al

291 Only congeners with detection frequencies (DF) >/= 75% were i

292 We first examine two Neotropical frog congeners with drastically different affinities to defor

293 DE-209 and -99 but also to a cocktail of BDE congeners with evidence of neurodevelopmental toxicity.

294 evaluated a concentration data set of PCDD/F congeners with four or more chlorines along with all 209

295 e activity comparable to their alkene-linked congeners with improved hysicochemical, ADME, and pharma

296 In addition, congeners with improved physicochemical properties were

297 ested that dechlorination proceeds to PCDD/F congeners with less than four chlorines.

298 Polychlorinated biphenyl (PCB) congeners with multiple ortho chlorine substituents and

299 motic stress enhanced the interaction of the congeners with the outward facing sites and profoundly m

300 containing prodrug (S)-Asp-FPMPC is the only congener within this series to demonstrate micromolar an

301 dazole dimers is the production of antipodal congeners without the corresponding enantiomers.