ライフサイエンスコーパス: congenital malformation

1 rinatal mortality, prematurity, toxaemia and congenital malformation.

2 lopmental basis of this clinically important congenital malformation.

3 HD) are collectively the most common form of congenital malformation.

4 numerary digits, or polydactyly, is a common congenital malformation.

5 erinatal mortality in the absence of a major congenital malformation.

6 pathogenesis of spina bifida-a common human congenital malformation.

7 ion are at increased risk of fetal death and congenital malformation.

8 s in families in which a person had multiple congenital malformations.

9 evere anterior neural tube defect-associated congenital malformations.

10 may explain the development of many sporadic congenital malformations.

11 king during pregnancy, preterm delivery, and congenital malformations.

12 t for gestational age, cesarean section, and congenital malformations.

13 phrenia, autism, intellectual disability and congenital malformations.

14 ere was no evidence for an increased risk of congenital malformations.

15 aternal to fetal circulation might attenuate congenital malformations.

16 ence after cardiac defects among major human congenital malformations.

17 splasia of the hip is one of the most common congenital malformations.

18 trimester of pregnancy only and the risk of congenital malformations.

19 is the role played by the human HOX genes in congenital malformations.

20 ve births, birthweight, and the frequency of congenital malformations.

21 eeks gestation) birth, and the occurrence of congenital malformations.

22 spring of irradiated females had one or more congenital malformations.

23 rnal use of folic acid antagonists and these congenital malformations.

24 omes characterized by mental retardation and congenital malformations.

25 ng data that mefloquine does not cause gross congenital malformations.

26 erebral hemorrhage due to ischemic stroke or congenital malformations.

27 infants were healthy at birth, with no major congenital malformations.

28 n associated with reduced incidence of other congenital malformations.

29 frequency of miscarriages or in the rate of congenital malformations.

30 h restriction, feeding problems, and various congenital malformations.

31 ion in fetal life could increase the risk of congenital malformations.

32 problems, musculoskeletal abnormalities, and congenital malformations.

33 testing of therapies and vaccines to prevent congenital malformations.

34 temisinin treatment on miscarriage and major congenital malformations.

35 case, and one newborn with microcephaly and congenital malformations.

36 en raised about a potential association with congenital malformations.

37 between-group difference in the frequency of congenital malformations.

38 tal outcomes, such as microcephaly and other congenital malformations.

39 birth, stillbirth, neonatal death, and major congenital malformations.

40 gnant diseases such as carcinomas, trauma or congenital malformations.

41 xcess of these compounds are associated with congenital malformations.

42 ing-Opitz syndrome characterized by multiple congenital malformations.

43 ver to severe neurological complications and congenital malformations.

44 st trimester, 721 had an infant with a major congenital malformation (25.3 [95% CI, 23.5-27.1] cases

45 Neural tube defects are severe congenital malformations affecting around one in every 1

46 Congenital malformations affecting multiple organ system

47 (cryptorchidism) is one of the most frequent congenital malformations, affecting 1-3% of newborn boys

48 e reading frame and lead to a broad range of congenital malformations, affecting craniofacial structu

49 s evidence of increased risk of diagnoses of congenital malformations after vaccination, possibly bec

50 We recorded no significant increased risk of congenital malformations, alopecia, or skin disorders.

51 ity as well as severe growth retardation and congenital malformations among surviving Atox1(-/-) prog

52 ders to migraine, neuropathic pain, and even congenital malformations and autism.

53 ng contributes to common diseases, including congenital malformations and cancer.

54 interrelationship between increased rates of congenital malformations and DNA mutations in the offspr

55 d both-parent exposure cases with a focus on congenital malformations and fetal loss.

56 While congenital malformations and genetic diseases are a lead

57 bearing age, with an increased risk of major congenital malformations and possible cognitive difficul

58 ill experience significantly higher rates of congenital malformations and spontaneous miscarriages co

59 sease manifestations including microcephaly, congenital malformation, and Guillain-Barre syndrome, Zi

60 rm labor, fetuses small for gestational age, congenital malformation, and the incidence of large plac

61 sorder characterized by bone marrow failure, congenital malformations, and cancer susceptibility.

62 medical records examined perinatal outcomes, congenital malformations, and developmental delay.

63 tidepressant exposure on perinatal outcomes, congenital malformations, and early growth and developme

64 x, maternal history of epilepsy, presence of congenital malformations, and gestational age.

65 ious human diseases, including microcephaly, congenital malformations, and Guillain-Barre syndrome.

66 is associated with reports of microcephaly, congenital malformations, and Guillain-Barre syndrome.

67 ncy and infect the developing fetus to cause congenital malformations, and its association with Guill

68 history, gestational age, birth weight, sex, congenital malformations, and parity).

69 g infertility, miscarriage, diabetes-related congenital malformations, and preeclampsia.

70 -for-gestational-age infants, preterm birth, congenital malformations, and stillbirth.

71 oblems, epilepsy, neuropathies, obesity, and congenital malformations are similar to those described

72 age (ARR, 1.19), stillbirth (ARR, 1.11), or congenital malformation (ARR, 0.90).

73 ge (ARR, 1.30; 95% CI, 1.07-1.57) but not of congenital malformation (ARR, 1.00; 95% CI, 0.83-1.20) o

74 fections (aRR, 1.42; 95% CI, 1.17-1.73), any congenital malformation (aRR, 1.48; 95% CI, 1.35-1.62),

75 reases in blood glucose levels, suggest that congenital malformations associated with diabetic pregna

76 an increased risk of miscarriage or of major congenital malformations associated with first-line trea

77 To date, tacrolimus has not been linked to congenital malformations but can cause reversible nephro

78 an important component, not only in cases of congenital malformations, but also in unexplained intrau

79 maternal and fetal complications (excluding congenital malformations) by comparing pregnant women wi

80 tion represents the only instance in which a congenital malformation can be prevented simply and cons

81 Congenital malformations can be manifested as combinatio

82 t doses lower than those required to produce congenital malformations can produce cognitive and behav

83 atenin signaling in human diseases including congenital malformations, cancer, and osteoporosis, and

84 autism spectrum disorders (ASD), and various congenital malformations (CM).

85 irths not exposed to APs were diagnosed with congenital malformations compared with 44.5 (95% CI, 40.

86 facial features, short stature, and distinct congenital malformations comprising choanal atresia, ana

87 sease conditions were within the sections of congenital malformations, deformities, and chromosomal a

88 ge syndrome (CdLS) is a dominantly inherited congenital malformation disorder, caused by mutations in

89 ly is just one of the clinical signs of this congenital malformation disorder.

90 syndrome is an autosomal-recessive multiple-congenital-malformation disorder characterized by multis

91 om the Latin American Collaborative Study of Congenital Malformations (ECLAMC), 154 cases from Latvia

92 rugs were associated with increased rates of congenital malformations (eg, spina bifida, cardiac anom

93 hs in the VLBW and LBW groups, respectively; congenital malformations explained 36% and 23% in the LB

94 escent mortality, with perinatal factors and congenital malformations explaining many of the deaths.

95 en 26 and before 37 weeks' gestation without congenital malformations, fetal growth restriction, or s

96 However, the absolute risk of congenital malformations following prenatal exposure to

97 e evolution of pregnancies and occurrence of congenital malformations following treatment by ICSI wer

98 l eligible babies (aged 1 h to 48 h, without congenital malformations) from hospital-based and commun

99 f Zika virus (ZIKV) and its association with congenital malformations has prompted the rapid developm

100 ic studies of Hirschsprung disease, a common congenital malformation, have identified eight genes wit

101 rtebrae to close at the midline, is a common congenital malformation in humans that is often synonymo

102 studies reporting varying risk estimates for congenital malformation in offspring of mothers undergoi

103 egnancy did not seem to be linked to overall congenital malformation in offspring, although risk incr

104 ression/anxiety, folate supplementation, and congenital malformation in the child.

105 ndromic craniosynostosis (NSC) is a frequent congenital malformation in which one or more cranial sut

106 xamined whether risk of hypospadias (i.e., a congenital malformation in which the opening of the peni

107 p vs 3 fetuses (1%) in the control group and congenital malformations in 17 neonates (5%) in the vita

108 We sought to compare the risk of major congenital malformations in asthmatic women exposed to a

109 drugs during pregnancy associated with major congenital malformations in children?

110 unifying etiology for the broad spectrum of congenital malformations in diabetic pregnancies.

111 NAD synthesis caused a deficiency of NAD and congenital malformations in humans and mice.

112 ing are hypothesized to underlie many common congenital malformations in humans including congenital

113 s been associated with some cases of cardiac congenital malformations in humans, also disrupts the pH

114 d palate syndromes are among the most common congenital malformations in humans.

115 f Fallot, resembling some of the most common congenital malformations in humans.

116 ects (NTDs), which are among the most common congenital malformations in humans.

117 been associated with microcephaly and other congenital malformations in infants as well as Guillain-

118 ications, birth weight, and the frequency of congenital malformations in live-born offspring.

119 Other congenital malformations in males (excluding those affec

120 on of an ataluren-based formulation reverses congenital malformations in the postnatal mouse eye, pro

121 h, stillbirth, small for gestational age, or congenital malformations) in women who underwent endosco

122 also characterized by growth retardation and congenital malformations, in particular craniofacial, up

123 ifficulties, structural brain abnormalities, congenital malformations including congenital heart dise

124 syndrome, a variable combination of multiple congenital malformations including heart defects.

125 gnant women with Zika virus (ZIKV) can cause congenital malformations including microcephaly, which h

126 velopment of 8 DS phenotypes, 4 of which are congenital malformations, including acute megakaryocytic

127 ch this region is deleted usually have major congenital malformations, including brain anomalies such

128 delay, persistent feeding difficulties, and congenital malformations, including brain anomalies.

129 e/velo-cardio-facial syndrome) have multiple congenital malformations, including cardiovascular defec

130 l malformations suspected prenatally and all congenital malformations, including chromosome anomalies

131 tion reduces the occurrence of several human congenital malformations, including craniofacial, heart

132 In Brazil, the virus has been linked to congenital malformations, including microcephaly and oth

133 tes (types 1 and 2) induces a broad array of congenital malformations, including neural tube defects

134 Congenital malformations, including neural tube defects

135 growth restriction, developmental delay, and congenital malformations, including neural tube, heart,

136 autosomal recessive mutant with a myriad of congenital malformations, including polydactyly and faci

137 ons in TGFBR1 or TGFBR2 cause multiple human congenital malformations, including soft palate cleft, w

138 Major congenital malformations, including those affecting the

139 ild-type grandprogeny, and the appearance of congenital malformations independent of maternal environ

140 R7 function is associated with a spectrum of congenital malformations, intellectual impairment, epile

141 related transcriptional repressor Hey2 cause congenital malformations involving the non-chamber atrio

142 The risk of congenital malformations is uncertain; the balance of ri

143 This important (but often unsuspected) congenital malformation may require alternative surgical

144 during pregnancy increases the risk of major congenital malformations (MCMs).

145 ts do not appear to be associated with major congenital malformations, more human data regarding pote

146 patients have had neonatal cardiomyopathy or congenital malformations, most commonly affecting the he

147 abortion secondary to a birth defect, major congenital malformations, neoplasia, or increased infect

148 of particular interest in view of the severe congenital malformations - 'neural tube defects' - that

149 left palate (CL/P) is one of the most common congenital malformations observed in humans, with 1 occu

150 ficantly associated with the risk of overall congenital malformations (odds ratio [OR], 0.88; 95% CI,

151 Periventricular heterotopia (PVH) is a congenital malformation of human cerebral cortex frequen

152 Based on MRI the congenital malformation of posterior fossa-rhombencephal

153 Interrupted aortic arch (IAA) is a rare congenital malformation of the aortic arch, which might

154 utosomal recessive disorder characterized by congenital malformation of the cerebellum and brainstem,

155 Hirschsprung disease is the most common congenital malformation of the enteric nervous system.

156 Holoprosencephaly (HPE) is the most common congenital malformation of the forebrain in human.

157 ated with holoprosencephaly, the most common congenital malformation of the forebrain.

158 Congenital malformation of the foregut is common in huma

159 sorder of connective tissue characterized by congenital malformation of the great toes and postnatal

160 muscle, tendon, ligament, and fascia and by congenital malformation of the great toes.

161 h or without cleft palate is the most common congenital malformation of the head and the third-most c

162 Congenital malformations of anorectal and genitourinary

163 e 22q11 and clinically by a constellation of congenital malformations of the aortic arch, heart, thym

164 ural tube defects (NTDs) are the most severe congenital malformations of the central nervous system.

165 Congenital malformations of the heart and circulatory sy

166 terized by early-onset diabetes mellitus and congenital malformations of the kidney, pancreas, and ge

167 In some patients, however, congenital malformations of the mitral apparatus may be

168 ation suffering from heart disease caused by congenital malformations of the outflow tract, an ELC1v-

169 epidemiologic evidence, we used the rate of congenital malformations of the reproductive system as a

170 gly linked to population-normalized rates of congenital malformations of the reproductive system in m

171 l hypoplasia, cardiac defects, microcephaly, congenital malformations of the skeleton, hypogonadism,

172 ed individuals with intellectual disability, congenital malformations, ophthalmologic anomalies, feed

173 rth or small for gestational age, but not of congenital malformation or stillbirth.

174 c antidepressant or SSRI exposure and either congenital malformations or developmental delay.

175 I exposure was significantly associated with congenital malformations or developmental delay.

176 Although few congenital malformations or neonatal infections were see

177 We excluded infants with major congenital malformations or obvious chromosomal disorder

178 Major congenital malformations overall and cardiac malformatio

179 does not meaningfully increase the risk for congenital malformations overall or cardiac malformation

180 Primary outcomes were major congenital malformations overall, 20 individual malforma

181 not associated with increased risk of major congenital malformations overall, any of the 20 individu

182 g the first trimester were studied for major congenital malformations (overall and organ specific) an

183 ic stroke in cerebral palsy; birth asphyxia, congenital malformations, placental pathology, and genet

184 nditions (i.e., autism spectrum disorder and congenital malformations), potentially indicating some c

185 isorder characterized by genome instability, congenital malformations, progressive bone marrow failur

186 herited disorder clinically characterized by congenital malformations, progressive bone marrow failur

187 y tract (CAKUT) comprise a large spectrum of congenital malformations ranging from severe manifestati

188 No significant differences were found in the congenital malformation rate, prematurity rate, and Apga

189 al growth and development: (low birthweight, congenital malformations, reduced head circumference), a

190 rmed at birth were identified from the local Congenital Malformation Register.

191 nd other risk factors were obtained from the Congenital Malformations Registry and vital records.

192 -control study by linking the New York State Congenital Malformations Registry to birth certificates

193 CE inhibitors had an increased risk of major congenital malformations (risk ratio, 2.71; 95 percent c

194 Adverse outcomes included 159 congenital malformations, six chromosomal abnormalities,

195 onatal intensive care unit (NICU) admission, congenital malformation, small for gestational age (SGA)

196 may be involved in the pathogenesis of human congenital malformations such as HC and PKD.

197 All congenital malformations suspected prenatally and all co

198 en mutated in the germline, give rise to the congenital malformation syndrome fibrodysplasia ossifica

199 3 of 55 cases (P < 5 x 10(-228)) of the rare congenital malformation syndrome.

200 perfamily members that cause disparate human congenital malformation syndromes interact genetically a

201 ects in such processes are a common cause of congenital malformation syndromes, and rapid progress is

202 ) is a common (1 in 3,000 live births) major congenital malformation that results in significant morb

203 like phenotype is one of the principal human congenital malformations that can be traced back to the

204 ion provides a mouse model for head and neck congenital malformations that frequently occur in humans

205 ations and delivered live singletons without congenital malformations (the analysis population).

206 unction of these signaling pathways leads to congenital malformation, the consequences of cardiac pro

207 cause of its causal relationship with severe congenital malformations, the ZIKV epidemic became an im

208 CI 0.45-1.34]; p=0.3645) or in risk of major congenital malformations (two [2%] of 109 [95% CI 0.22-6

209 sulted from a problem with the aortic valve: congenital malformation unassociated with infective endo

210 Adjusted risk for congenital malformation was 4.98% in exposed offspring v

211 Results: Congenital malformation was observed in 2037 (4.97%) exp

212 The risks of fetal death and congenital malformation were not related to whether the

213 Such congenital malformations were barely significant for ID

214 Major congenital malformations were identified from linked vit

215 Two congenital malformations were identified: clubfoot in on

216 Two congenital malformations were reported (one bilateral ca

217 asphyxia-related neonatal complications, and congenital malformations, which in turn are associated w

218 eural tube defects (NTDs) are common, severe congenital malformations whose causation involves multip

219 tube defects (NTD) are clinically important congenital malformations whose molecular mechanisms are

220 cleft lip and/or palate (NSCLP) is a common congenital malformation with a multifactorial model of i

221 Jeune syndrome is a rare congenital malformation with a reported incidence of 1 i

222 Measurements: Congenital malformation, with subanalyses for congenital

223 wall (VBW) defects are among the most common congenital malformations, yet their embryonic origin and