ライフサイエンスコーパス: congression

1 romosomes at the metaphase plate (chromosome congression).

2 n, spindle pole organization, and chromosome congression.

3 sponsive signal transduction, and chromosome congression.

4 lk1 at the kinetochore to promote chromosome congression.

5 on at the kinetochore and rescued chromosome congression.

6 ay contribute to Xorbit's role in chromosome congression.

7 olar spindle capable of efficient chromosome congression.

8 heckpoint control and for correct chromosome congression.

9 l wall breakdown is not required for nuclear congression.

10 he cell, and correlates with slow chromosome congression.

11 ort results in chromosome bi-orientation and congression.

12 d2 became undetectable soon after chromosome congression.

13 llation, but is not essential for chromosome congression.

14 owards the metaphase plate during chromosome congression.

15 microtubule motors play an important role in congression.

16 rotubule plus end-tip positioning to mediate congression.

17 lation are required for efficient chromosome congression.

18 indle equator, a process known as chromosome congression.

19 early mitosis promoting efficient chromosome congression.

20 e of cell fusion, causing a block in nuclear congression.

21 reattachment/detachment cycle that prevents congression.

22 may be important for its role in chromosome congression.

23 acological agents and for mitotic chromosome congression.

24 ochore-microtubule attachment and chromosome congression.

25 in the vicinity of the spindle poles without congression.

26 in spindle assembly and metaphase chromosome congression.

27 n prophase facilitates subsequent chromosome congression.

28 romoting checkpoint signaling and chromosome congression.

29 r proper spindle architecture and chromosome congression.

30 is spatially regulated to achieve chromosome congression.

31 ble self-organizing mechanism for chromosome congression.

32 duced centromere stretch, delayed chromosome congression, alignment defects, and severe missegregatio

33 spindle is required for efficient chromosome congression and accurate chromosome segregation to ensur

34 his was accompanied by defects in chromosome congression and alignment of the maternal and paternal m

35 as a protein that is required for chromosome congression and alignment.

36 nesin-10 family) are required for chromosome congression and alignment; Kif4A and Kif4B (members of t

37 tachment, resulting in failure of chromosome congression and an increased propensity for lagging chro

38 ional centrosomes have a delay in chromosome congression and anaphase onset, which can be explained b

39 ole in turning off the SAC, in promoting the congression and bi-orientation of bivalents on meiosis I

40 tors implicating small GTPases in chromosome congression and cytokinesis.

41 yeast mating, cell fusion is followed by the congression and fusion of the two nuclei.

42 Chromosome biorientation promotes congression and generates tension that stabilizes kineto

43 g, we captured the precise timing of nuclear congression and identified two minus end-directed motors

44 of two sister kinetochores during chromosome congression and imply that vertebrate kinetochores consi

45 the bipolar spindle and promotes chromosome congression and interkinetochore tension during mitosis.

46 sis during metaphase, even though chromosome congression and metaphase alignment do not appear to be

47 zygotic division, PLK-1-dependent chromosome congression and metaphase plate alignment are necessary

48 arms extend toward spindle poles during both congression and metaphase.

49 al component that monitors proper chromosome congression and mitotic timing during cell division.

50 lly condensed chromosomes, failed chromosome congression and multiple centrosomes.

51 losses in Plk1 activity impaired chromosome congression and produced severe anaphase dysfunction cha

52 ctivity of CENP-E serves to power chromosome congression and provides a flexible, motile tether linki

53 stability relies upon efficacious chromosome congression and regulation by the spindle assembly check

54 Chromosome dynamics during congression and segregation are controlled by opposing f

55 In the absence of Nup358, chromosome congression and segregation are severely perturbed.

56 Chromosome congression and segregation have been widely known to be

57 oped system for observing meiotic chromosome congression and segregation in living maize cells, we sh

58 ion and is required for efficient chromosome congression and segregation in mammalian cells.

59 he spindle is a driving force for chromosome congression and segregation in mitosis.

60 Coordination of cytokinesis with chromosome congression and segregation is critical for proper cell

61 Chromosome congression and segregation require the proper attachmen

62 rs to coordinate cytokinesis with chromosome congression and segregation.

63 ndle microtubules and drives both chromosome congression and segregation.

64 and CENP-F, which are involved in chromosome congression and spindle assembly checkpoint signaling.

65 ulation significantly compromises chromosome congression and the deposition of HJURP-CENP-A complexes

66 ses defects in both prometaphase chromosomal congression and the spindle checkpoint; however, the mec

67 n of microtubule dynamics, proper chromosome congression, and correction of improper kinetochore-micr

68 romosome arm orientation, delayed chromosome congression, and sensitized cells to nocodazole.

69 ed roles in kinetochore assembly, chromosome congression, and spindle checkpoint signaling.

70 ed NDC80 complex are required for chromosome congression, and their disruption results in mitotic arr

71 metaphase, started to fade during chromosome congression, and then disappeared at midanaphase.

72 cell fusion is necessary to complete nuclear congression, and there exists a SNARE-mediated, Sey1p-in

73 le dynamics, spindle assembly and chromosome congression, and thus cell cycle progression during mous

74 tic spindle that still manifests the classic congression architecture.

75 hat spindle length regulation and chromosome congression are intrinsic to the spindle and largely ind

76 n-like motor protein required for chromosome congression at prometaphase.

77 chores and resulted in defects in chromosome congression at the metaphase plate.

78 of ald (mps1) meiotic mutants that complete congression at wild-type rates, but have widely varying

79 ter stable attachment, throughout chromosome congression, at metaphase, and throughout anaphase A, CE

80 ons with microtubules, and direct chromosome congression, biorientation, error correction, and anapha

81 K accumulated at leading kinetochores during congression but not during segregation.

82 assembly checkpoint (SAC) and in chromosome congression, but the role of its catalytic activity rema

83 Kinetochores mediate chromosome congression by either sliding along the lattice of spind

84 Perturbing chromosome congression by other means also resulted in failure to d

85 cerevisiae) was shown to mediate chromosome congression by promoting catastrophe of long kinetochore

86 PEFs are proposed to facilitate congression by pushing chromosomes away from spindle pol

87 roteins, Cin8p and Kip1p, mediate chromosome congression by suppressing kMT plus-end assembly of long

88 tants, suggesting that malorientation during congression commits these chromosomes to eventually nond

89 ciations, however, this effect on chromosome congression could be phenocopied.

90 ndent Plk1 localization induced a chromosome congression defect and compromised the spindle checkpoin

91 ts, disoriented mitotic spindles, chromosome congression defects and delayed mitotic progression.

92 ora B kinase activity, and lethal chromosome congression defects in cancer cells.

93 nents, impaired KT-MT attachment, chromosome congression defects, and whole-chromosome instability.

94 ng of Class I proteins and causes chromosome congression defects, but does not perturb spindle format

95 Loss of Shot also leads to chromosome congression defects, cell cycle progression delay, and d

96 chment, chromosome misalignment, chromosomal congression defects, lagging chromosomes, and chromosome

97 loss of CENP-E and consequently, chromosome congression defects.

98 disorganized spindles and severe chromosome congression defects.

99 We conclude that efficient nuclear congression depends on the cooperation of two minus end-

100 nucleus-centrosome attachment and pronuclear congression during fertilization.

101 e report a dual mechanism underlying nuclear congression during fission yeast karyogamy upon mating o

102 Net1 is required for chromosome congression during metaphase and generation of stable ki

103 otein that has been implicated in chromosome congression during mitosis, and we found that this form

104 e polar ejection force needed for chromosome congression during mitosis.

105 tor protein that is essential for chromosome congression during mitosis.

106 trosome separation but also their chromosome congression errors and mitotic delay.

107 rometaphase and display increased chromosome congression errors.

108 Strong mitotic arrest and chromosome congression failure occurred after Pp1-87B downregulatio

109 heless, chromosomes show typical patterns of congression, fast poleward motion, and oscillatory motio

110 perturbing spindle formation and chromosome congression following maturation.

111 tivity as an essential feature of chromosome congression from poles and localized PP1 delivery by CEN

112 equired to establish and maintain chromosome congression have distinguishable requirements.

113 These data support a model in which nuclear congression in budding yeast occurs by plus end MT captu

114 Chromosome congression in cells also requires positive charge on th

115 d to facilitate Bub3 activity and chromosome congression in higher eukaryotes.

116 cell lines and were required for chromosome congression in mitotic HeLa cells, the gradients were st

117 known as pronuclear migration or as nuclear congression in Saccharomyces cerevisiae.

118 a fundamental physical limit for maintaining congression in small spindles in the face of assembly no

119 ffects spindle pole formation and chromosome congression in vivo.

120 light chain, may be important for chromosome congression, in addition to having a role in the transpo

121 hase A but is not responsible for chromosome congression, interkinetochore tension, or the establishm

122 kinetochore, and in its absence, chromosome congression is defective.

123 Thus, CENP-E-driven chromosome congression is guided by microtubule detyrosination.

124 Nuclear congression is inhibited by drugs that perturb the actin

125 1F activity contributes to normal chromosome congression, kinetochore spacing, and anaphase A rates.

126 passenger complex (CPC) controls chromosome congression, kinetochore-microtubule attachments, and sp

127 This congression mechanism depended on the kinetochore-associ

128 We find that nuclear congression occurs through the interaction of MT plus en

129 cteristic feature of mitotic spindles is the congression of chromosomes near the spindle equator, a p

130 bres were destabilized, leading to defective congression of chromosomes to the metaphase plate and pe

131 spindle microtubules by kinetochores and the congression of chromosomes to the metaphase plate.

132 tosis in yeast, dramatically interferes with congression of chromosomes to the metaphase plate.

133 ombination with polar ejection forces, drive congression of chromosomes to the metaphase plate.

134 material during cell division depends on the congression of chromosomes to the spindle equator before

135 The congression of chromosomes to the spindle equator involv

136 bilizes fibres of the mitotic spindle to aid congression of chromosomes.

137 d mitotic division, AIR-2 may coordinate the congression of metaphase chromosomes with the subsequent

138 We found that congression of pole-proximal chromosomes depended on spe

139 -end-directed kinetochore motor required for congression of pole-proximal chromosomes.

140 e have studied this process by following the congression of pole-proximal kinetochores and their subs

141 evere defects in chromosome condensation and congression on the metaphase plate result in delayed ana

142 t from mitosis without detectable chromosome congression or anaphase movements.

143 pole organization and separation, chromosome congression or segregation, and anaphase spindle elongat

144 tly revised by the discovery that chromosome congression precedes metaphase I arrest.

145 Klp2-dependent nuclear congression proceeds at constant speed, whereas dynein a

146 which delay chromosome individualization and congression, putting the oocyte at risk of aneuploidy.

147 understanding of how prometaphase chromosome congression relates to anaphase chromosome segregation.

148 It is generally assumed that congression requires that chromosomes are connected to t

149 Chromosome congression requires the stable attachment of microtubul

150 The discovery that congression returns nonexchange chromosomes to the metap

151 hore is critical for facilitating chromosome congression, segregation, and checkpoint signaling.

152 oncomitant increase in defects in chromosome congression, separation, and segregation.

153 These cells exhibited defects in chromosomal congression, sister chromatid cohesion and spindle posit

154 isopeptidases, causes a defect in chromosome congression that depends on its precise kinetochore targ

155 During congression, the kinetochore moving away from its spindl

156 homologous chromosomes, promotes chromosome congression through the action of the chromokinesin KLP-

157 e centrosome/nucleus complex, for chromosome congression to a well ordered metaphase plate, and for t

158 support a model in which CENP-E functions in congression to tether kinetochores to dynamic microtubul

159 upports a model in which CENP-E functions in congression to tether kinetochores to the disassembling

160 and the inability of chromosomes to complete congression to the equatorial plane for proper mitotic s

161 ast kinesin-8 contributes both to chromosome congression to the metaphase plate and to the coupling o

162 alian cells at prophase inhibited chromosome congression to the metaphase plate with many chromosomes

163 e capture at prometaphase, timely chromosome congression to the metaphase plate, and proper interkine

164 is essential for proper centromere motility, congression to the metaphase plate, and subsequent anaph

165 oblasts (MEFs) display defects in chromosome congression to the metaphase plate, severe chromosome mi

166 ssential for neither microtubule capture nor congression to the metaphase plate.

167 dynactin inhibition did not block chromosome congression to the spindle equator in prometaphase, or s

168 a strong bilateral defect, in which nuclear congression was completed but fusion did not occur.

169 are followed by reattachment and successful congression, whereas in Ska-depleted cells, detached kin

170 s in Nnf1R-depleted cells prevent chromosome congression, whereas those in Mcm21R-depleted cells inte