ライフサイエンスコーパス: coniferyl

1 Endogenous coniferyl, 5-hydroxyconiferyl, and sinapyl aldehydes wer

2 -dependent reduction of p-coumaryl, caffeyl, coniferyl, 5-hydroxyconiferyl, and sinapyl aldehydes, wh

3 also catalyzes the formation of eugenol from coniferyl acetate and is only 46% identical to CbIGS1 an

4 basil eugenol-forming enzyme that also uses coniferyl acetate and NADPH as substrates but catalyzes

5 enylpropenes, possess an enzyme that can use coniferyl acetate and NADPH to form eugenol.

6 Using coniferyl acetate as a substrate, FaEGS1a and FaEGS1b ca

7 ugenol in P. hybrida are biosynthesized from coniferyl acetate in reactions catalyzed by isoeugenol s

8 rall, these data support the conclusion that coniferyl acetate is the substrate of isoeugenol synthas

9 parodii, in the absence of IGS activity the coniferyl acetate substrate is converted by an as yet un

10 r to CbEGS2 (82% identity) and that converts coniferyl acetate to eugenol.

11 ObEGS1 and PhIGS1 both utilize coniferyl acetate, are 52% sequence identical, and belon

12 ot found in anise) from coumaryl acetate and coniferyl acetate, respectively.

13 crom for coumaryl acetate and 230 microm for coniferyl acetate.

14 ter of coniferyl alcohol, hypothesized to be coniferyl acetate.

15 n in planta is one electron oxidation of (E)-coniferyl alcohol (CA) to generate the radical intermedi

16 "monolignols") p-coumaryl alcohol (pCoumA), coniferyl alcohol (ConA), and sinapyl alcohol (SinA) has

17 In particular, coniferyl alcohol 4-O-glucoside accumulated to massive a

18 monooxygenase, ferulic acid/coniferaldehyde/coniferyl alcohol 5-hydoxylase (F5H).

19 this P450 is a ferulic acid/coniferaldehyde/coniferyl alcohol 5-hydroxylase (F5H), and is capable of

20 nsferase activity and is most efficient with coniferyl alcohol among the alcohol substrates tested.

21 oplast cultures were cofed with 13C6-labeled coniferyl alcohol and a 13C4-labeled dimer of coniferyl

22 iates in the biosynthesis of the monolignols coniferyl alcohol and sinapyl alcohol.

23 dative polymerization of two major monomers, coniferyl alcohol and sinapyl alcohol.

24 hat the enzyme also uses coniferaldehyde and coniferyl alcohol as substrates.

25 providing evidence for CCR's involvement in coniferyl alcohol biosynthesis.

26 in capable of stereoselectively coupling two coniferyl alcohol derived radical species, in this case

27 criminately etherifying the para-hydroxyl of coniferyl alcohol even in the presence of excess sinapyl

28 onsiderable increases in both p-coumaryl and coniferyl alcohol formation and excretion.

29 ylation of ferulic acid, coniferaldehyde and coniferyl alcohol in the pathways leading to sinapic aci

30 ether with ferulic acid, coniferaldehyde, or coniferyl alcohol in the presence of native or recombina

31 s the naturally dominant sinapyl alcohol and coniferyl alcohol lignin monomers alters the lignin stru

32 directed radical-radical coupling, where two coniferyl alcohol radical substrates are bound per prote

33 s stereoselective coupling (using either two coniferyl alcohol radicals or a radical and a monolignol

34 e coupling and subsequent cyclization of two coniferyl alcohol radicals to pinoresinol as the committ

35 Dilignols derived from coniferyl alcohol such as G(8-5)G, G(8-O-4)G and isodihy

36 Equilibrium binding assays revealed that coniferyl alcohol was only weakly bound to the DP, with

37 ng linoleic, linolenic and benzoic acids and coniferyl alcohol, are precursors of odorous volatiles.

38 coniferin, the glycosylated storage form of coniferyl alcohol, as a substrate of the enzymes, wherea

39 soeugenol synthase (PhIGS1) from an ester of coniferyl alcohol, hypothesized to be coniferyl acetate.

40 taining secondary metabolites suggested that coniferyl alcohol, in addition to being used in lignin a

41 ethanol, furfuryl alcohol, (Z)-3-hexen-1-ol, coniferyl alcohol, isoamyl alcohol and linolenic acid.

42 d to proceed by single-electron oxidation of coniferyl alcohol, subsequent reaction with one of the o

43 .1.1.195), which converts coniferaldehyde to coniferyl alcohol, the primary lignin precursor in pines

44 lic alcohols, such as coumaryl, sinapyl, and coniferyl alcohol, to the corresponding aldehydes and th

45 native catalyst for O-methylation leading to coniferyl alcohol, was not up-regulated under any of the

46 e in coniferin content without any change in coniferyl alcohol, whereas no change in syringin content

47 f action is presumed to involve capture of E-coniferyl alcohol-derived free-radical intermediates, wi

48 That lignin contained fewer coniferyl alcohol-derived units and significant levels o

49 -beta-coupling with sinapyl alcohol and then coniferyl alcohol.

50 ates the condensed guaiacyl lignin precursor coniferyl alcohol.

51 oniferyl alcohol and a 13C4-labeled dimer of coniferyl alcohol.

52 so could not be detected for feruloyl-CoA or coniferyl alcohol.

53 be up-regulated in response to a deficit of coniferyl alcohol.

54 hesis of the two monolignols, p-coumaryl and coniferyl alcohols (lignin/lignan precursors).

55 rmed by their elemental composition, such as coniferyl aldehyde (C10H10O3), sinapyl aldehyde (C11H12O

56 hydroxylation and at the same time ensures a coniferyl aldehyde 5-hydroxylase (CAld5H)-mediated biosy

57 analysis of LsM88 in yeast identified it as coniferyl aldehyde 5-hydroxylase (CAld5H).

58 In contrast, ferulate had no effect on coniferyl aldehyde 5-hydroxylation.

59 or the presence of a CAld5H/AldOMT-catalyzed coniferyl aldehyde 5-hydroxylation/methylation pathway t

60 More significantly, when coniferyl aldehyde and ferulate were present together, c

61 aldehyde, ferulic acid, p-coumaric acid, and coniferyl aldehyde at trace levels in particulate matter

62 However, recent recognition that coniferyl aldehyde prevents 5-hydroxyferulate biosynthes

63 ylation supports our previous discovery that coniferyl aldehyde prevents ferulate 5-hydroxylation and

64 acyl to syringyl monolignol biosynthesis via coniferyl aldehyde that contrasts with the generally acc

65 Together, CAld5H and COMT converted coniferyl aldehyde to sinapyl aldehyde, suggesting a CAl

66 aldehyde and ferulate were present together, coniferyl aldehyde was a noncompetitive inhibitor (K(i)

67 ough either route, k(cat)/K(m) of CAld5H for coniferyl aldehyde was approximately 140 times greater t

68 can readily accommodate p-coumaryl aldehyde, coniferyl aldehyde, 4-hydroxy-(2E)-nonenal, and 2-alkena

69 ng tissue, and that the hydroxylated form of coniferyl aldehyde, 5-hydroxyconiferyl aldehyde, is an a

70 Therefore, in the presence of coniferyl aldehyde, ferulate 5-hydroxylation does not oc

71 ty between CjapOBP1, CjapOBP2 and citral and coniferyl aldehyde, respectively.

72 ngyl monolignol can be synthesized only from coniferyl aldehyde.

73 lpropanal substrates, such as p-coumaryl and coniferyl aldehydes in vitro.

74 Arabidopsis plants showed that the levels of coniferyl and sinapyl alcohol 4-O-glucosides that accumu

75 as a control point in the regulation of the coniferyl and sinapyl alcohol branches of this pathway.

76 p-coumaryl alcohol; they resulted from both coniferyl and sinapyl alcohol in the wild-type plants.

77 nin of antisense-CAD tobacco contained fewer coniferyl and sinapyl alcohol-derived units that were co

78 s, in agreement with the reduced flux toward coniferyl and sinapyl alcohol.

79 sical guaiacyl/syringyl lignin (derived from coniferyl and sinapyl alcohols).

80 sical lignins, which are derived mainly from coniferyl and sinapyl alcohols.

81 plant is conventionally biosynthesized from coniferyl and sinapyl alcohols.

82 ersus the two normally dominant monolignols, coniferyl and sinapyl alcohols.

83 ll as high levels of coniferin and syringin (coniferyl and sinapyl-4-O-glycosides), compounds not pre

84 Four coniferyl and two morinol derivatives were characterised

85 alysis of the metabolites in the p-coumaryl, coniferyl, and sinapyl alcohol branches of this pathway.

86 variety of monolignols including p-coumaryl, coniferyl, and sinapyl alcohols to produce the three pri

87 of tricin with the monolignols (p-coumaryl, coniferyl, and sinapyl alcohols) were synthesized along

88 mers, the so-called monolignols (p-coumaryl, coniferyl, and sinapyl alcohols).

89 zation of the three monolignols, p-coumaryl, coniferyl, and sinapyl alcohols.

90 n the growing lignin polymer and then either coniferyl or sinapyl alcohol, or another 5-hydroxyconife

91 vo operation of the CAld5H/COMT pathway from coniferyl to sinapyl aldehydes via 5-hydroxyconiferyl al