ライフサイエンスコーパス: conjugative

1 carry a tcp locus, suggesting that they are conjugative.

2 t function; recipient ESX-1 mutants are hypo-conjugative.

3 donor strain; ESX-1 donor mutants are hyper-conjugative.

4 strongly suggesting that these plasmids are conjugative.

5 emonstrated that bla(CTX-M) was located on a conjugative 65-MDa IncK plasmid.

6 transition between homoaromaticity and hyper(conjugative) antiaromaticity.

7 cells lack a mechanism for disassembling the conjugative apparatus when signals become limiting.

8 eeded for expression and construction of the conjugative apparatus.

9 with and sequestering some component of the conjugative apparatus.

10 Conjugative assembly genome engineering (CAGE) is a prec

11 We developed hierarchical conjugative assembly genome engineering (CAGE) to merge

12 oin DNA for the initiation and completion of conjugative bacterial gene transfer.

13 quences and the tcp genes, which can mediate conjugative C. perfringens plasmid transfer.

14 Decreases in TraR activity and conjugative competence could be accounted for by dilutio

15 Donors grown in batch culture retained conjugative competence following signal removal, even wh

16 C on the accumulation of acyl-HSL and on the conjugative competence of strain C58.

17 While the rate of development of conjugative competence was not significantly affected by

18 and functional organization of the F plasmid conjugative coupling protein TraD by coimmunoprecipitati

19 of DNA translocases, such as the VirD4/TrwB conjugative coupling proteins and the chromosome segrega

20 re, inclusion of sterically induced biphenyl conjugative decoupling between chromophore pi-donor subs

21 in twisting of chromophores and affected the conjugative delocalization of the pi-electrons, which pr

22 Conjugative DNA plasmids, which harbor a wide range of a

23 Specificity of conjugative DNA processing in these plasmids involves bo

24 tiprotein relaxosome complex responsible for conjugative DNA transfer (CDT) between bacterial cells.

25 progenitor ParA/MinD-like ATPase to promote conjugative DNA transfer by: (i) nucleating relaxosome a

26 Successful conjugative DNA transfer depends on key catalytic compon

27 and Bordetella pertussis Ptl systems support conjugative DNA transfer in E. coli and trigger P. aerug

28 Conjugative DNA transfer is a highly conserved process f

29 a potential recipient cell stimulates donor conjugative DNA transfer upon contact.

30 phonates would inhibit relaxase activity and conjugative DNA transfer.

31 transferases (UGT) are the dominant phase II conjugative drug metabolism enzymes that also play a cen

32 (pN)), and is enhanced by the inductive and conjugative effect of scaffold materials with pi-electro

33 his is not primarily due to classical (hyper)conjugative effects.

34 In such cases, (hyper)conjugative electronic effects determine the reactivity,

35 genetic element ICEBs1 is an integrative and conjugative element (a conjugative transposon) found in

36 genetic element ICEBs1 is an integrative and conjugative element (a conjugative transposon) found in

37 ICEBs1 is an integrative and conjugative element (conjugative transposon) integrated

38 Here we study transfer of an integrative and conjugative element (ICE) among individual live bacteria

39 genetic element ICEBs1 is an integrative and conjugative element (ICE) found in Bacillus subtilis.

40 ystem carried by a streptococcal integrative conjugative element (ICE), ICESe2.

41 hybrid variant of CTXPhi and an integrative conjugative element (ICE), leading to their establishmen

42 Here, we show that an integrating conjugative element (ICE)-encoded DNase, which we name I

43 e island, suggest it moves as an integrative conjugative element (ICE).

44 at nicks an origin of transfer (oriT) on the conjugative element and initiates the 5'-to-3' transfer

45 Lactococcus lactis MG 1363 contains a 60 kb conjugative element called the sex factor capable of hig

46 Plasmid pAD1 is a 60-kb conjugative element commonly found in clinical isolates

47 ICEBs1 is an integrative and conjugative element found in the chromosome of Bacillus

48 emm12 outbreak isolates: the integrative and conjugative element ICE-emm12, encoding genes for tetrac

49 ribute to acquisition of the integrative and conjugative element ICEBs1 by Bacillus subtilis.

50 cillus subtilis carrying the integrative and conjugative element ICEBs1 can transfer three different

51 than to the only other potential integrative conjugative element known from S. aureus, Tn5801.

52 In particular, an integrative conjugative element named RAGE (for Rickettsiales amplif

53 array of conjugal elements (integrative and conjugative element or ICE) that reside in bacterial chr

54 ne caused by insertion of an integrative and conjugative element.

55 A2 loci are present on conserved integrative conjugative elements (ICE) and are transferred and share

56 plasmids and IncA/C-related integrative and conjugative elements (ICE) from commensal and pathogenic

57 Integrative and conjugative elements (ICEs) are self-mobile genetic elem

58 Integrating conjugative elements (ICEs) are self-transmissible mobil

59 Integrative and conjugative elements (ICEs) are ubiquitous mobile geneti

60 Integrative and conjugative elements (ICEs) contribute to the rapid evol

61 Integrative conjugative elements (ICEs) enable horizontal gene trans

62 ctors in the transmission of integrative and conjugative elements (ICEs) has not been extensively exp

63 Integrative and conjugative elements (ICEs), a.k.a. conjugative transpos

64 Integrative and conjugative elements (ICEs), also known as conjugative t

65 Integrative and conjugative elements (ICEs), formerly called conjugative

66 icity islands, including the integrative and conjugative elements (ICEs), the gene-transfer agents (G

67 Integrative and conjugative elements (ICEs), which are chromosomal mobil

68 bile genetic elements, including integrative conjugative elements (ICEs), with the local bacterial po

69 can be mobilized by co-resident integrating conjugative elements (ICEs).

70 belong to the superfamily of integrative and conjugative elements (ICEs).

71 ve been classified as mobile integrative and conjugative elements (ICEs).

72 Integrative and conjugative elements (ICEs, a.k.a. conjugative transposo

73 Integrative and conjugative elements (ICEs, also known as conjugative tr

74 h transformation, along with integrative and conjugative elements and phage-related chromosomal islan

75 Conjugative elements are capable of self-transfer and al

76 Plasmids that can be mobilized by conjugative elements are generally thought to contain an

77 preceded by the insertion of integrative and conjugative elements conferring tetracycline resistance

78 sity of exclusion systems within families of conjugative elements has received little attention.

79 genomes, indicates roles for integrative and conjugative elements in the evolution of pneumococci and

80 Conjugative elements often encode entry exclusion system

81 nd nonmobilizable plasmids and indicate that conjugative elements play a role in horizontal gene tran

82 : 'conjugative transposons', or 'integrative conjugative elements'.

83 hage genomes, on plasmids and on integrating conjugative elements, and are likely to be involved in a

84 hat acquisition of ICEBs1, and perhaps other conjugative elements, is robust and not easily avoided b

85 egrated mobile elements, such as integrating conjugative elements, requiring site-specific targeting

86 be closely related to a group of integrating conjugative elements, which use conjugative transfer for

87 plasmids, phages, integrons and integrative conjugative elements.

88 lusion in the SXT/R391 family of integrative conjugative elements.

89 usion determinants within a single family of conjugative elements.

90 embers of the SXT/R391 family of integrative conjugative elements.

91 GT isoform 2B7 (UGT2B7), which catalyzes the conjugative elimination of opioid, antiviral, and antica

92 ids generally encode proteins that block the conjugative entry of identical or similar plasmids into

93 Instead, CdiA-CT(536) import requires conjugative F pili.

94 Qbeta, an ssRNA phage specific for the conjugative F-pilus, has a T = 3 icosahedral lattice of

95 these data define the helicase motifs of the conjugative factor TraI from Salmonella pCU1 and reveal

96 presence of excisionase and integrase genes, conjugative functions and multiple insertion sequence el

97 activity in vivo, and several have wild-type conjugative functions when expressed at normal levels.

98 F plasmid pB171, which has no genes encoding conjugative functions.

99 t cells is detected by donor cells to induce conjugative genetic transfer.

100 These blooms boosted conjugative HGT of the colicin-plasmid p2 from Salmonell

101 aling replicon preference (ISKpn18 prefers a conjugative IncA/C2 plasmid), local action (IS26), regio

102 The conjugative initiator proteins are key players in the DN

103 s the different balance of electrostatic and conjugative interactions in the two types of anomeric sy

104 ransferred into recipient P. aeruginosa by a conjugative mechanism, via a type IV pilus, encoded in P

105 he same evolutionary trajectories as its non-conjugative mini-replicon in the same and other species.

106 Symbiosis islands are integrative and conjugative mobile genetic elements that convert nonsymb

107 asmid R1162 encodes proteins that enable its conjugative mobilization between bacterial cells.

108 r (oriT) is an essential initial step in the conjugative mobilization of plasmid DNA.

109 This system is, in turn, controlled by the conjugative opines produced by crown gall tumors induced

110 These structures reveal that conjugative pili are assemblies of stoichiometric protei

111 re, function, and especially the dynamics of conjugative pili are poorly understood.

112 Conjugative pili are widespread bacterial appendages tha

113 ecific bacteriophage R17, a phage that binds conjugative pili elaborated by IncF plasmid R1, to defin

114 ging to characterize the dynamics of F-pili (conjugative pili encoded by the F plasmid of Escherichia

115 o shed light on the remarkable properties of conjugative pili in bacterial secretion and phage infect

116 njugation requires thin, flexible filaments (conjugative pili) that are elaborated by DNA donor cells

117 Among conjugative pili, the F "sex" pilus encoded by the F pla

118 Exchange of DNA between bacteria involves conjugative pili.

119 rate transfer, but required for formation of conjugative pili.

120 erial conjugation involves the transfer of a conjugative plasmid as a single strand.

121 onjugation, transfer of a single strand of a conjugative plasmid between bacteria, requires sequence-

122 TrbB, a periplasmic protein encoded by the conjugative plasmid F, has a predicted thioredoxin-like

123 The Rts1 conjugative plasmid from a clinical isolate of P. vulgar

124 1-kb RI on the chromosome, or transformed to conjugative plasmid in the two BJAB strains.

125 is the process by which a single strand of a conjugative plasmid is transferred from donor to recipie

126 derivative of the pGO1/pSK41 staphylococcal conjugative plasmid lineage, and pGO400::SCCmec (pRM27)

127 A conjugative plasmid of 55,706 bp (pBRZ01) carrying the v

128 Phage C-1 requires a conjugative plasmid of the IncC group, while Hgal1 requi

129 of Enterococcus faecalis cells carrying the conjugative plasmid pCF10 is controlled by multiple regu

130 udy, we evaluated the protein TraM, from the conjugative plasmid pIP501, as a potential vaccine candi

131 TraM of the G+ broad host range Enterococcus conjugative plasmid pIP501.

132 the microbiota, to evaluate the role of the conjugative plasmid pPD1 expressing bacteriocin 21 in en

133 The conjugative plasmid pTR2030 has been used extensively to

134 full-length TrwK, the VirB4 homologue in the conjugative plasmid R388, determined by single-particle

135 TrwD, the VirB11 homologue in conjugative plasmid R388, is a member of the large secre

136 system encoded by broad-host-range IncPalpha conjugative plasmid RP4 present in adjacent donor cells.

137 cherichia coli when coresident with the IncP conjugative plasmid RP4, but not F.

138 Bacterial conjugation, transfer of a single conjugative plasmid strand between bacteria, diversifies

139 NA, is suppressed in the recipient cell by a conjugative plasmid system centered on the product of th

140 rs through the highly coordinated process of conjugative plasmid transfer (CPT).

141 n, competence, virulence, biofilm formation, conjugative plasmid transfer and antibiotic resistance.

142 For many gram-positive pathogens, conjugative plasmid transfer is an important means of sp

143 Conjugative plasmid transfer is key to the ability of ba

144 Conjugative plasmid transfer is the most important means

145 e system against bacteriophage infection and conjugative plasmid transfer.

146 ed oxidative folding enzyme is important for conjugative plasmid transfer.

147 rs possessing a pheromone responsive-type of conjugative plasmid, and was invariably accompanied by t

148 ted to be peculiar to an Escherichia coli F' conjugative plasmid, not generally significant, and to o

149 uced sequentially into mammalian cells had a conjugative plasmid.

150 paired as a donor of RP4, a broad-host-range conjugative plasmid.

151 system encoded by the Escherichia coli R388 conjugative plasmid.

152 RP62a blocks the transfer of staphylococcal conjugative plasmids and harbors nine cas-csm genes.

153 phages, more phages specializing for various conjugative plasmids and infecting different bacterial s

154 ICEs and conjugative plasmids are found in many bacteria and are

155 me a serious global human health threat, and conjugative plasmids are important drivers of the rapid

156 Conjugative plasmids are key agents of horizontal gene t

157 Conjugative plasmids are the principal genetic elements

158 Conjugative plasmids are typically locked in intergenomi

159 In the absence of TraR, bacteria carrying conjugative plasmids become more susceptible to external

160 e Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific double

161 However, although many conjugative plasmids carry beneficial traits, all plasmi

162 In contrast, conjugative plasmids commonly encode TrfA and have an or

163 The multidrug resistance-encoding IncA/C conjugative plasmids disseminate antibiotic resistance g

164 Pheromone-responsive conjugative plasmids encoding bacteriocins are common am

165 S. aureus genomes, except in a set of large conjugative plasmids encoding resistance genes that show

166 plasmids, suggesting that the utilization of conjugative plasmids for cell attachment and entry compr

167 Conjugative plasmids generally encode proteins that bloc

168 The role of CSM in limiting the spread of conjugative plasmids in Staphylococcus epidermidis was f

169 xtended spectrum beta-lactamases (ESBLs) via conjugative plasmids is facilitating the increasingly wi

170 ic resistance is most commonly propagated by conjugative plasmids like pLW1043, the first vancomycin-

171 We propose that the pheromone-responsive, conjugative plasmids of E. faecalis have retained Prg-li

172 his transmission has been mediated mainly by conjugative plasmids of the pheromone-responsive and bro

173 es later remobilized and inserted onto other conjugative plasmids or some iap/ibp plasmids acquired a

174 Transfer of conjugative plasmids requires relaxases, proteins that c

175 Unlike conjugative plasmids that are extra-chromosomal and repl

176 n Enterococcus faecalis, lateral transfer of conjugative plasmids that encode antibiotic resistance a

177 olicing: copy number control (CNC) among non-conjugative plasmids, a class of extra-chromosomal verti

178 rom invasion by foreign DNA such as viruses, conjugative plasmids, and transposable elements.

179 Unlike many bacterial conjugative plasmids, pXF-RIV5 and pXFAS01 do not carry

180 lolevivirus predate phage specialization for conjugative plasmids, suggesting that the utilization of

181 The existence of conjugative plasmids, therefore, presents a paradox beca

182 ne account for co-adaptation of bacteria and conjugative plasmids.

183 n substantially affect carriage of the major conjugative plasmids.

184 ting responses by bacteria carrying specific conjugative plasmids.

185 s present on all SCCmec types and pGO1/pSK41 conjugative plasmids.

186 se gene present in nearly all staphylococcal conjugative plasmids.

187 r and at selectively killing cells harboring conjugative plasmids.

188 of antimicrobial resistance (AMR), often on conjugative plasmids.

189 iple DNA sites to recruit the plasmid to the conjugative pore.

190 TrbB may function in the conjugative process by serving as a disulfide bond isome

191 activities on substrates not involved in the conjugative process.

192 t that complex topological rearrangements of conjugative proteins must occur during mating to enable

193 ve oxidants and electrophilic agents through conjugative reactions and by enhancing cellular antioxid

194 LVTLVFV), which is used in signaling between conjugative recipient and donor cells.

195 encoding gene, traA, located in the proposed conjugative region of the plasmid, abolished plasmid tra

196 at are nanomolar inhibitors of the F plasmid conjugative relaxase in vitro.

197 smid mobilization did not require the ICEBs1 conjugative relaxase or cotransfer of ICEBs1, indicating

198 eting translocation signals presented by the conjugative relaxase TraI of plasmid R1.

199 Thus, the inhibition of conjugative relaxases is a potentially novel antimicrobi

200 o transfer origins (oriT) recognized by MOBP conjugative relaxases.

201 ata indicate that the domain responsible for conjugative repression resides in the central region of

202 Specifically, we found that a large conjugative resistance plasmid follows the same evolutio

203 Variants of the MB80 conjugative resistance plasmid were identified in other

204 The TraI protein from the conjugative Salmonella plasmid pCU1 fulfills these key c

205 gioselectivity is related to a strong, hyper-conjugative sigma(Calpha-Cbeta)-pi(C horizontal lineC) o

206 Using a thermosensitive conjugative system, we provide evidence that conjugation

207 Here, we show that VirC1 promotes conjugative T-DNA transfer by stimulating generation of

208 V secretion system (T4SS), a relative of the conjugative T4SS, we demonstrate that catalytically acti

209 Conjugative T4SSs comprise 12 proteins named VirB1-11 an

210 Relaxases are essential for conjugative transfer and act by cleaving DNA strands and

211 asmid R1162 is a large protein essential for conjugative transfer and containing two different and ph

212 lasmid genes involved in plasmid replication conjugative transfer and maintenance, while the remainde

213 Expression of conjugative transfer and virulence functions of the Ente

214 In addition, conjugative transfer experiments proved that TraM is ess

215 ious studies addressing regulation of CTnDOT conjugative transfer focused primarily on the 13-kb tran

216 integrating conjugative elements, which use conjugative transfer for horizontal propagation but stab

217 ts, we examined the kinetics of induction of conjugative transfer in response to exogenous acyl-homos

218 e polar localization of chemotaxis proteins, conjugative transfer machinery, type IV pili, and cellul

219 te transient enterobacterial blooms in which conjugative transfer occurs at unprecedented rates.

220 e the expression of this gas reporter to the conjugative transfer of a bacterial plasmid in a soil ma

221 broad-host-range plasmid R1162 can initiate conjugative transfer of a plasmid from a 19-bp locus tha

222 Conjugative transfer of a plasmid from a plasmid-bearing

223 The conjugative transfer of Agrobacterium plasmids is contro

224 Conjugative transfer of Agrobacterium Ti plasmids is reg

225 The conjugative transfer of bacterial F plasmids relies on T

226 open reading frames (ORFs) known to mediate conjugative transfer of C. perfringens plasmid pCW3.

227 RteR inhibits conjugative transfer of CTnDOT by targeting the transfer

228 Conjugative transfer of CTnDOT is regulated upon exposur

229 cascade of regulatory events results in the conjugative transfer of CTnDOT upon Tc induction.

230 Here we demonstrate the capture and conjugative transfer of excised SCCmec.

231 -mediated recombination, for the capture and conjugative transfer of genomic islands.

232 nt of the ICEBs1 conjugation machinery, that conjugative transfer of ICEBs1 from B. subtilis likely i

233 y yddE) is required for conjugation and that conjugative transfer of ICEBs1 requires a conserved ATPa

234 rve as a site for initiation of ICE-mediated conjugative transfer of large regions of chromosomal DNA

235 ption of both types of signals is needed for conjugative transfer of mobile DNA elements via type IV

236 Conjugative transfer of plasmid DNA via close cell-cell

237 functional aspects of the relaxase-mediated conjugative transfer of plasmid pCU1.

238 antagonistic signaling molecules to regulate conjugative transfer of tetracycline-resistance plasmid

239 operon in Enterococcus faecalis controlling conjugative transfer of the antibiotic resistance plasmi

240 Conjugative transfer of the Enterococcus faecalis plasmi

241 elicase activities, initiates and drives the conjugative transfer of the Escherichia coli F plasmid.

242 Conjugative transfer of the Ti plasmids of Agrobacterium

243 c comparisons predict type IV secretion-like conjugative transfer operons encoded on the shared plasm

244 A novel and functional conjugative transfer system identified in O119:H2 entero

245 into the bacterial genome and are capable of conjugative transfer to a new host and, often, intracell

246 onally carries all of the genes required for conjugative transfer, including the regulatory genes tra

247 Early in F plasmid conjugative transfer, the F relaxase, TraI, cleaves one

248 the pCF10-encoded T4SS as monitored by pCF10 conjugative transfer.

249 type IV secretion system (T4SS) required for conjugative transfer.

250 (iii) many etx plasmids should be capable of conjugative transfer.

251 stems contribute to the overall frequency of conjugative transfer.

252 nation assemble as a single circular ICE for conjugative transfer.

253 plasmid DNA between bacterial cells through conjugative transfer.

254 e in S. aureus (NES), which is essential for conjugative transfer.

255 55 carries two alleles of traR that regulate conjugative transfer.

256 CTnDOT is a 65-kb conjugative transposon (CTn) in Bacteroides spp. that co

257 CTnDOT is a Bacteroides conjugative transposon (CTn) that has facilitated the sp

258 A newly discovered Bacteroides conjugative transposon (CTn), CTnBST, integrates more si

259 The Bacteroides conjugative transposon CTnDOT encodes an integrase, IntD

260 gh the integrase (IntDOT) of the Bacteroides conjugative transposon CTnDOT has been classified as a m

261 Excision of the Bacteroides conjugative transposon CTnDOT is stimulated by tetracycl

262 e investigated the effect of the Bacteroides conjugative transposon CTnDOT on expression of chromosom

263 DOT is a tyrosine recombinase encoded by the conjugative transposon CTnDOT.

264 assembled genomes revealed a 49-kbp putative conjugative transposon exclusive to this hospital clonal

265 strongest hotspots include regions flanking conjugative transposon ICE6013, the staphylococcal casse

266 CTnDOT is a 65-kb conjugative transposon present in Bacteroides spp. that

267 y polymerase encoded by rumA'B from the IncJ conjugative transposon R391.

268 Rescue of the conjugative transposon sequences required the recipient

269 regulated, as were genes associated with the conjugative transposon Tn5397 including a group II intro

270 d the structure of the ArdA protein from the conjugative transposon Tn916 and find that it has a nove

271 at excision resulted from the interaction of conjugative transposon Tn916 and the related mobile elem

272 he intercellular transposition region of the conjugative transposon Tn916 from the bacterial pathogen

273 ophages lambda, P22, L5, HP1, and P2 and the conjugative transposon Tn916.

274 is an integrative and conjugative element (a conjugative transposon) found in Bacillus subtilis.

275 is an integrative and conjugative element (a conjugative transposon) found in the Bacillus subtilis c

276 1 is an integrative and conjugative element (conjugative transposon) integrated into trnS-leu2 in Bac

277 CTnBST, a newly discovered Bacteroides conjugative transposon, carries an erythromycin resistan

278 of the chromosome that contained a putative conjugative transposon, which had been tentatively desig

279 nce-conferring mutation and a highly related conjugative transposon.

280 Conjugative transposons (CTns) are major contributors to

281 Several conjugative transposons (CTns) encode recombinases that

282 ome is the first step during the transfer of conjugative transposons (CTns) to a recipient.

283 Mobile genetic elements, such as conjugative transposons (CTns), have contributed to an i

284 Plasmids, conjugative transposons and phage frequently encode anti

285 Foreign DNA elements such as plasmids and conjugative transposons are constantly entering new bact

286 Conjugative transposons are generally resistant to DNA r

287 Tn916-like conjugative transposons carrying antibiotic resistance g

288 posons require gene products from coresident conjugative transposons for excision and transfer to rec

289 different genomic site - hence their name: 'conjugative transposons', or 'integrative conjugative el

290 nd conjugative elements (ICEs, also known as conjugative transposons) are mobile elements that are fo

291 ative and conjugative elements (ICEs, a.k.a. conjugative transposons) are modular mobile genetic elem

292 tive and conjugative elements (ICEs), a.k.a. conjugative transposons, are mobile genetic elements inv

293 d conjugative elements (ICEs), also known as conjugative transposons, are mobile genetic elements tha

294 conjugative elements (ICEs), formerly called conjugative transposons, have been implicated in the pro

295 in CD37 reveals the presence of two putative conjugative transposons.

296 egative phage and the mobilisation of DNA by conjugative transposons.

297 elerating effects and compared them with the conjugative TS stabilization by pi-acceptors.

298 Thus far, well studied conjugative type IV secretion systems (T4SS) are of Gram

299 Type VI secretion, and, unexpectedly, conjugative type IV secretion within competing bacteria,

300 of macrophages, relying on the presence of a conjugative virulence plasmid harboring a 21-kb pathogen