ライフサイエンスコーパス: connective

1 cted to the buccal ganglia, commissures, and connectives.

2 find that disulfide bridges are abundant in connective and liver ECM.

3 y lineages and nerves in relationship to the connectives and commissures.

4 us works, the system of longitudinal fibers (connectives) and transverse axons (commissures) has been

5 e biofabrication strategies in neural, skin, connective, and muscle tissue engineering are explored.

6 native cross-coupling of carbenoids offers a connective approach to olefins capable of precisely targ

7 med bone contained higher trabecular number, connective density, and bone mineral density.

8 The reduction in connective dimensionality with retention of electronic f

9 Sulfonyl Fluorides (SASFs) as a new class of connective hub in concert with a diverse selection of cl

10 Test2 showed significantly less connective or other tissue than control and Test1.

11 ercentage of vital bone, residual graft, and connective or other tissue.

12 of vital bone, residual graft material, and connective/other tissue.

13 consequences of mTBI on lung NK1R levels and connective protein expression enhance neutrophil recruit

14 Despite down-regulated gene expression of connective proteins, the presence of an intact pulmonary

15 r interplay between tumor cells, nerves, and connective stroma.

16 click chemistry with recent developments in connective SuFEx-technologies.

17 rcentages of vital bone, residual graft, and connective tissue (CT)/other were determined via histomo

18 In the intramuscular connective tissue (IMCT) of both muscles, a decrease in

19 ining revealed a greater proportion of dense connective tissue (P=0.02) in women compared with men.

20 Fibrosis of the subsynovial connective tissue (SSCT) is a pathognomonic change in ca

21 by Menninghaus et al. fails because its main connective tissue - "negative emotions" - is beyond the

22 elevates plasma Hcy-thiolactone and leads to connective tissue abnormalities that affect the cardiova

23 ould be evaluated routinely in patients with connective tissue abnormalities, which will enable a bet

24 homa in addition to a number of skeletal and connective tissue abnormalities.

25 sis, a disease in which excessive amounts of connective tissue accumulate in response to physical dam

26 l epithelium length; epithelium on the root; connective tissue adaptation; and soft tissue thickness

27 clinically cause significant destruction of connective tissue and bone.

28 derived from the liver extracellular matrix, connective tissue and epithelium, and proteins related t

29 smoplastic reaction through the synthesis of connective tissue and extracellular matrix, inducing loc

30 ed by inflammatory infiltrates, necrosis and connective tissue and fat replacement of the affected mu

31 Type I collagen is a key protein of most connective tissue and its up-regulation is required for

32 1.2-1.5]), liver disease (RR 2.2 [1.6-2.9]), connective tissue and rheumatic diseases (RR 1.5 [1.3-1.

33 ZB was predominantly localized to endomysial connective tissue and to a lesser extent muscle membrane

34 Since mechanosensory cells in connective tissue are surrounded by a disordered network

35 When taking 1.0 mm connective tissue attachment into account, 60% 3D BA-RSA

36 er bone porosity, trabecular separation, and connective tissue attachment loss (CTAL) as well as redu

37 D100 presented greater bone volume and lower connective tissue attachment loss (CTAL) than group EP (

38 ise effect of collagen glycation on gingival connective tissue biology is not fully understood.

39 fan syndrome (MFS) is a systemic disorder of connective tissue caused by pathogenic variants in the f

40 Mechanical injury to connective tissue causes changes in collagen structure a

41 deposition, inflammatory cell retention, and connective tissue cell differentiation, respectively.

42 SOX2 induced proliferation of epithelial and connective tissue cells and promoted angiogenesis.

43 tumors (aggressive fibromatosis) arise from connective tissue cells or fibroblasts.

44 to create 3D open scaffolds for adhesion of connective tissue cells through well-defined adhesion pl

45 ces appeared as fluid filled sacculi between connective tissue compartments accountable for distendin

46 sis is defined as an excessive deposition of connective tissue components and can affect virtually ev

47 etal muscle and instead consisted of fibrous connective tissue composed of type I and type III collag

48 a heterogenous group of diseases that cause connective tissue defects.

49 es cellular proliferation, angiogenesis, and connective tissue deposition, suggesting vessel healing

50 HC revealed disrupted junctional epithelium, connective tissue destruction, bacterial invasion, incre

51 related to cell cycle progression as well as connective tissue development and function.

52 f a 3D human lymphatic network within native connective tissue devoid of any exogenous material such

53 Loeys-Dietz syndrome (LDS) is a systemic connective tissue disease (CTD) associated with a predis

54 All had connective tissue disease (CTD) serologies, spirometry,

55 biopsies from 30 patients with idiopathic or connective tissue disease (CTD)-related ILD and 13 contr

56 using multivariable Cox regression analysis: connective tissue disease (hazard ratio [HR] 2.94, 95% c

57 Mixed connective tissue disease (MCTD) is a rare and complex a

58 ral bridges may be pathologically altered in connective tissue disease as evidenced by the ultrastruc

59 Bruck Syndrome is a connective tissue disease associated with inactivating m

60 Systemic sclerosis is an autoimmune connective tissue disease in which T cells play a promin

61 r Ehlers-Danlos syndrome is a rare inherited connective tissue disease secondary to mutations within

62 s-Danlos syndrome (vEDS) is a rare inherited connective tissue disease secondary to mutations within

63 was 49+/-14 years, 78% were female, 33% had connective tissue disease, 52% were in New York Heart As

64 od for IPF (kappaw=0.71 [IQR 0.64-0.77]) and connective tissue disease-related interstitial lung dise

65 olesterol biosynthesis, liver cirrhosis, and connective tissue disease.

66 limited specificity for a single autoimmune connective tissue disease.

67 Inflammatory connective tissue diseases (CTD) like lupus and rheumato

68 Autoimmune connective tissue diseases are clinically variable, maki

69 Autoimmune connective tissue diseases arise in a stepwise fashion f

70 These mutants may be useful in treating connective tissue diseases associated with increased met

71 s (55 healthy, 54 with spondyloarthritis and connective tissue diseases) were studied.

72 highest cause-specific mortality of all the connective tissue diseases, and the aetiology of this co

73 ease that presents mixed features with other connective tissue diseases, such as systemic lupus eryth

74 flammation in transplant organ rejection and connective tissue diseases.

75 thic PAH and are rare in PAH associated with connective tissue diseases.

76 digestive diseases; (6) musculoskeletal and connective tissue diseases; and (7) genitourinary diseas

77 temic sclerosis is a systemic autoimmune and connective tissue disorder associated with the human leu

78 los syndrome (vEDS) is an autosomal-dominant connective tissue disorder caused by heterozygous mutati

79 Marfan syndrome (MFS) is a heritable connective tissue disorder caused by mutations in FBN1,

80 Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in fibril

81 syndrome (MFS) is a highly variable genetic connective tissue disorder caused by mutations in the ca

82 Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FB

83 Bruck syndrome (BS) is a connective tissue disorder characterized at the molecula

84 pathogenesis of systemic sclerosis (SSc), a connective tissue disorder characterized by autoimmunity

85 e alter mitochondrial function and cause the connective tissue disorder cutis laxa.

86 ibromuscular dysplasia was present in 62.7%, connective tissue disorder in 4.9%, and systemic inflamm

87 ers-Danlos syndrome (vEDS) is a rare genetic connective tissue disorder secondary to pathogenic varia

88 Marfan syndrome (MFS) is a connective tissue disorder that results in aortic root w

89 MTSL2 mutations cause an autosomal recessive connective tissue disorder, geleophysic dysplasia 1 (GPH

90 r cases across the 2 cohorts had a diagnosed connective tissue disorder.

91 s, with the exception of musculoskeletal and connective tissue disorders (992 [8.69% per annum] vs 83

92 myocarditis, and myocarditis associated with connective tissue disorders and may be beneficial in chr

93 s crucial for elucidating pathomechanisms of connective tissue disorders characterized by ECM deficie

94 with respiratory, musculoskeletal system and connective tissue disorders is more prevalent in Whites.

95 ed with MCVD (cardiomyopathies, arrhythmias, connective tissue disorders, and familial hypercholester

96 gthen the overlap between SCAD and renal and connective tissue disorders, and we highlight several ne

97 ants in several genes, such as those causing connective tissue disorders, have been implicated; howev

98 B-cell lineage hematologic malignancies and connective tissue disorders.

99 eatment of several major systemic autoimmune connective tissue disorders: systemic lupus erythematosu

100 Connective tissue displays a large compositional and str

101 ew variant of Ehlers-Danlos syndrome causing connective tissue disruptions in multiple organs.

102 factors, aging, and trauma all contribute to connective tissue dysfunction and motivate the need for

103 In mammals, the tendon connective tissue experiences and resists physical force

104 s in the collagen and glycoprotein phases of connective tissue extracellular matrix (ECM).

105 ation in wdSCCs; yet tenascin C retention in connective tissue extracellular matrix suggests the rigi

106 ts from the maxillary tuberosity are rich in connective tissue fibers, with minimal presence of fatty

107 Here we isolate and culture connective tissue fibroblasts from highly regenerative m

108 ize and enhanced tissue repair (strengthened connective tissue formation, improved microvascular form

109 Connective tissue graft (CTG) and enamel matrix derivati

110 The present study shows 2-year results of a connective tissue graft (CTG) associated with LLLT in th

111 of this trial was to assess the outcome of a connective tissue graft (CTG) in the esthetic zone of si

112 redictability of the free gingival graft and connective tissue graft (CTG) techniques are highlighted

113 uccal gingival recession (bREC), effect of a connective tissue graft (CTG) when combined with a bucca

114 lly advanced tunnel flap (TUN) combined with connective tissue graft (CTG) when compared to the trape

115 d patient-centered outcomes of subepithelial connective tissue graft (CTG) with and without enamel ma

116 mes of MAGRs following CAF with or without a connective tissue graft (CTG).

117 r dermal matrix [ADM], collagen matrix [CM], connective tissue graft [CTG]) are able to significantly

118 ques in combination with soft tissue grafts (connective tissue graft [CTG], collagen matrix [CM], and

119 of clinical long-term results 20 years after connective tissue grafting (CTG) or guided tissue regene

120 Connective tissue grafting has a beneficial effect on th

121 sutures in the palatal donor sites following connective tissue grafting via the SIT.

122 Combination therapy of papilla preservation, connective tissue grafting, and coronally advanced flaps

123 tions at palatal donor area of subepithelial connective tissue grafts (CTG) between cyanoacrylates ti

124 this study was to compare thick versus thin connective tissue grafts (CTG) for the treatment of ging

125 Connective tissue grafts (CTGs) and coronally advanced f

126 ted a greater GR reduction for subepithelial connective tissue grafts (SCTG) + coronally advanced fla

127 ompared two different types of subepithelial connective tissue grafts (SCTG) considering clinical par

128 ound healing of donor sites of subepithelial connective tissue grafts (SCTG), harvested by the single

129 tes have been proposed to replace autogenous connective tissue grafts, therefore the aims of this stu

130 Palatal biopsies, in the form of connective tissue grafts, were obtained from periodontal

131 Because secretion of the profibrotic connective tissue growth factor (CCN2) increased signifi

132 Pathways of liver fibrosis are controlled by connective tissue growth factor (CCN2).

133 Connective tissue growth factor (CTGF or CCN2) is a matr

134 Recent studies revealed that connective tissue growth factor (CTGF) aggravates the fi

135 cytosol, increase expression of YAP and TAZ connective tissue growth factor (CTGF) and Cyr61 target

136 he protein levels of 2 profibrosis proteins, connective tissue growth factor (CTGF) and TGF-beta1, in

137 ed the signaling of Smad3 and p53 to produce connective tissue growth factor (CTGF) and then resulted

138 Delivery of connective tissue growth factor (CTGF) into full-transec

139 Connective tissue growth factor (CTGF) is a secreted gly

140 Connective tissue growth factor (CTGF) is known to regul

141 Connective tissue growth factor (CTGF) up-regulation ind

142 We identified connective tissue growth factor (CTGF), a matricellular

143 Connective tissue growth factor (CTGF), a matrix-associa

144 Increasing evidence indicates that connective tissue growth factor (CTGF), a multifunctiona

145 expression of YAP-regulated genes, including connective tissue growth factor (CTGF), and cysteine-ric

146 in-1, collagen I, alpha-smooth muscle actin, connective tissue growth factor (CTGF), and plasminogen

147 TGF-beta), TGF-beta receptor 1 (TGF-betaR1), connective tissue growth factor (CTGF), E-cadherin, SRY-

148 jury markers such as interleukin-18 (IL-18), connective tissue growth factor (CTGF), neutrophil gelat

149 and ameliorated by blocking YAP1/TAZ target connective tissue growth factor (CTGF).

150 for expression of the subplate neuron marker connective tissue growth factor (CTGF).

151 targeting cell cycle regulator cyclin A and connective tissue growth factor (CTGF).

152 aturation through the regulated secretion of connective tissue growth factor (CTGF).

153 fter injury requires fine-tune regulation of connective tissue growth factor (Ctgf).

154 Several lines of evidence indicate that connective tissue growth factor (CTGF/CCN2) stimulates c

155 collagen VI, myocilin), matricellular genes (connective tissue growth factor [CTGF], secreted protein

156 expression of two TEAD-dependent genes, the connective tissue growth factor and amphiregulin genes.

157 in the levels of alpha-smooth muscle actin, connective tissue growth factor and fibronectin, and dec

158 collagen/fibronectin deposition, as well as connective tissue growth factor and matrix metalloprotei

159 ic RHOA effector, and elevated expression of connective tissue growth factor and smooth muscle actin.

160 mRNA levels of profibrotic genes, including connective tissue growth factor and tissue inhibitor of

161 e myosins, NotchR and Wnt pathway genes, and connective tissue growth factor by Pofut1 in skeletal mu

162 ro-fibrotic targets including ICAM-1 and the connective tissue growth factor CTGF.

163 at were capable of dose-dependently reducing connective tissue growth factor gene expression in vitro

164 -fibronectin, alpha smooth muscle actin, and connective tissue growth factor) and stabilized or impro

165 (transforming growth factor)-beta and CTGF (connective tissue growth factor) levels.

166 P1(-/-)) in mice disinhibited TGFbeta1-CTGF (connective tissue growth factor) signaling, leading to s

167 transforming growth factor-beta-1) and CTGF (connective tissue growth factor), reduced fibroblast pro

168 rine protease inhibitor, clade E, member 1), connective tissue growth factor, and collagen I].

169 luding overexpression of fibronectin 1 (FN), connective tissue growth factor, and other genes.

170 ding fibronectin, alpha-smooth muscle actin, connective tissue growth factor, collagen I, and TGF-bet

171 cation network factor 2, previously known as connective tissue growth factor, CTGF) using a specific

172 t plasminogen activator inhibitor-1 (PAI-1), connective tissue growth factor, fibronectin, and p21 in

173 ents within individual target mRNAs, such as connective tissue growth factor, induced hyper-adhesive,

174 ransforming growth factor-beta1 (TGF-beta1), connective tissue growth factor, matrix metalloproteinas

175 agonists of transforming growth factor-beta, connective tissue growth factor, several tyrosine kinase

176 wnstream effectors SMAD3 phosphorylation and connective tissue growth factor.

177 stoma overexpressed/cysteine-rich protein 61/connective tissue growth factor/nephroblastoma overexpre

178 thelial cells play a key role in stimulating connective tissue healing through a FOXO1-dependent mech

179 ted possible involvement of keratinocytes in connective tissue healing.

180 g early stages, which likely translates into connective tissue impairment in DS patients.

181 e same processes, which specify the basis of connective tissue impairment observed in DS patients, po

182 , raising the possibility of broad roles for connective tissue in adult positional information.

183 emical evaluation to determine the extent of connective tissue inflammatory infiltrate (CTII) using t

184 Dense connective tissue injuries have limited repair, due to t

185 Maintenance of connective tissue integrity is fundamental to sustain fu

186 asal epithelium positioned at the epithelial-connective tissue interface (ECTI), separating the basal

187 er, the majority of the bone, cartilage, and connective tissue is derived from the neural crest.

188 Connective tissue is involved in driving regenerating fi

189 Connective tissue is one of the four major types of anim

190 peutic avenue for functional rejuvenation of connective tissue is reprogrammed fibroblast replacement

191 As connective tissue is ubiquitously distributed throughout

192 ults revealed less gingival inflammation and connective tissue loss in the L+H groups compared with t

193 ived from animal sources, predominantly from connective tissue mast cells in pig mucosa.

194 ls were used as "surrogates" for mucosal and connective tissue mast cells, respectively, and their re

195 e number of blood vessels and sub-epithelial connective tissue matrix components within the wound bed

196 hosphorylation, neuropeptide biogenesis, and connective tissue maturation.

197 osphate/phosphate ratio is the cause of soft connective tissue mineralization in these disorders.

198 Tuberous sclerosis complex-related connective tissue nevi are not limited to the lower back

199 cation, size, and histological appearance of connective tissue nevi in patients with TSC.

200 To describe the clinical characteristics of connective tissue nevi on the trunk and extremities of p

201 Connective tissue nevi were categorized per anatomic loc

202 complex (TSC) frequently develop collagenous connective tissue nevi.

203 We observed a decrease in a cerebriform connective tissue nevus and a reduction in pain in child

204 [19-70] years) with TSC (56%) had at least 1 connective tissue nevus on the trunk or thighs; of these

205 The juxtacanalicular connective tissue of the trabecular meshwork together wi

206 SIL, without significant down-regulation of connective tissue or transforming growth factor-beta sig

207 ed stromal progenitor performance related to connective tissue organization as well as muscle develop

208 The main expansion then occurs in the connective tissue outside the islet, which remains more

209 doexfoliation (PEX) syndrome exhibit various connective tissue pathologies associated with dysregulat

210 In rare pathologic conditions, connective tissue phenotype mast cells (MC(TC)s) can be

211 Nonimmunological connective tissue phenotypes in humans are common among

212 l delay, visceral and cardiac malformations, connective tissue presentations with arterial involvemen

213 apamycin (90.3% and 82.9%), respectively, 2) connective tissue progenitor cells, 3) platelet-derived

214 Connective tissue progenitor cells, platelet-derived gro

215 formed blastema, the spatial coordinates of connective tissue progenitors are predictive of their ul

216 ogether with kidney, smooth muscle, and limb connective tissue progenitors from the lateral plate mes

217 r ability to hydrolyse meat myofibrillar and connective tissue protein extracts to produce bioactive

218 and thermal denaturation temperature of the connective tissue proteins (second peak in the DSC therm

219 with excessive accumulation of extracellular connective tissue proteins.

220 However, connective tissue proteome dynamics remain largely undef

221 nd the outer, orbital layer inserts into the connective tissue pulley.

222 pic delivery of Tgfbeta1 protein into nipple connective tissue reduced epidermal proliferation.

223 growth (growth hormone binding protein), and connective tissue remodeling (MMP3).

224 ms by diminishing inflammation and promoting connective tissue repair.

225 Fibroblasts are then cultured to produce connective tissue rich in extracellular matrix (stage 2)

226 The overproduction of connective tissue shares features with mammalian wound h

227 es have been described in various species as connective tissue structures "bridging" small cranio-cer

228 as greater in the alveolar septa than in the connective tissue surrounding the airways or vessels.

229 ndon and bone are attached by a transitional connective tissue that is morphologically graded from te

230 Fibrosis, the progressive accumulation of connective tissue that occurs in response to injury, cau

231 Tendon is a functionally important connective tissue that transmits force between skeletal

232 d, subsequently, differentiate into bone and connective tissue to form the mandible.

233 nd clinical management of three intermediate connective tissue tumors: desmoid tumor (DT) or aggressi

234 tly increased new bone formation and reduced connective tissue volume after 42 days demonstrating tha

235 tissue as either skin, fat, glands, ducts or connective tissue was demonstrated with an overall accur

236 ecently to genetic diseases characterized by connective tissue wasting (Penttinen syndrome) or overgr

237 ssed that inspire the need to replace native connective tissue with biomaterials.

238 nimmunological features, including skeletal, connective tissue, and vascular abnormalities, poor post

239 e a cartilaginous endoskeleton surrounded by connective tissue, but lack skeletal muscle.

240 an syndrome (MFS) is a heritable disorder of connective tissue, caused by mutations in the fibrillin-

241 s, modulation of infrastructural components (connective tissue, CT; glycocalyx) of donor organs, and

242 These novel data redefine adaptation in connective tissue, highlighting the fundamental importan

243 r invasive malignant epithelial cells in the connective tissue, keratin pearls in the OSCC, and ducts

244 a family with a congenital-onset disorder of connective tissue, manifesting as early-onset joint hype

245 ndicate that muscle functions as a planarian connective tissue, raising the possibility of broad role

246 this feat by means of elastic compliance of connective tissue, which passively redistributes the ove

247 essential for inducing the formation of new connective tissue, which requires the generation of sign

248 terogeneous group of hereditary disorders of connective tissue, with common features including joint

249 inflammatory infiltrate on the subepithelial connective tissue.

250 ined by aberrant accumulation of collagenous connective tissue.

251 transport to the development of skeletal and connective tissue.

252 lls were detected both in the epithelium and connective tissue.

253 and is the most common inherited disease of connective tissue.

254 ral proteins that are prevalent in mammalian connective tissue.

255 y determines the properties and functions of connective tissue.

256 dered in patients presenting with congenital connective tissue/myopathy overlap disorders with joint

257 ne = 20.47%, porcine = 19.52%, P = 0.82) and connective tissue/other (bovine = 43.32%, porcine = 49.2

258 bone formation, residual graft material, and connective tissue/other when ridge preservation is accom

259 nt a series of genetic evaluations for known connective-tissue disorders, but the evaluations were un

260 roblastic properties and sprouted to form 3D connective-tissue networks.

261 lasts lose contractility, leading to reduced connective-tissue stiffness.

262 & Microbe, Pundir et al. (2019) report that connective-tissue-type mast cells spy on bacterial commu

263 The adhesion of soft connective tissues (tendons, ligaments, and cartilages)

264 lance and wound-healing response of gingival connective tissues affected by diabetes mellitus or agin

265 files of mast cells isolated from peripheral connective tissues and basophils isolated from spleen an

266 w that 3D collagen gels, major components of connective tissues and extracellular matrix (ECM), are s

267 w that 3D collagen gels, major components of connective tissues and extracellular matrix, are signifi

268 re is to link a fundamental understanding of connective tissues and their multiscale properties to be

269 At 6 days p.i, virus was found in connective tissues and vasculature of the gastrointestin

270 The structure and mechanics of many connective tissues are dictated by a collagen-rich extra

271 mine the biomechanics of collagen fibrils in connective tissues are still poorly understood.

272 tisic acid (HGA) is elevated and deposits in connective tissues as ochronotic pigment.

273 s in the collagen and glycoprotein phases of connective tissues by exploiting the spatially distinct

274 Mature connective tissues demonstrate highly specialised proper

275 he complexities of cell migration in fibrous connective tissues from three separate but interdependen

276 Our work shows that muscle and cartilage connective tissues harbor progenitor cells capable of fu

277 Collagen forms the structural scaffold of connective tissues in all mammals.

278 SPGs) are important structural components of connective tissues in essentially all metazoan organisms

279 se sclerotome resulted in defects in fibrous connective tissues in the spine.

280 redefined the cellular origins of periocular connective tissues interacting with the EOMs, which do n

281 a precursor protein that is expressed by the connective tissues of the craniofacial skeleton, namely,

282 e localized fibrotic disorders of the penile connective tissues that can substantially impair a patie

283 nce the majority of the bones, cartilage and connective tissues that comprise the head and face are d

284 ucture-function relationships in native soft connective tissues that may be used to guide material de

285 Our findings indicate that injury to dense connective tissues under prestrain alters boundary const

286 SSc results in dysfunctional connective tissues with excessive profibrotic signaling,

287 Connective tissues within the synovial joints are charac

288 ssues, including muscles, blood vessels, and connective tissues, adapts to mechanical strains in the

289 ese mechanisms may be of importance in other connective tissues, and the key to unraveling cell-matri

290 With recent advances in the engineering of connective tissues, including arteries, we are on the cu

291 ease in Sox9 expression in muscle-associated connective tissues, tendons, and bones led to hypoplasia

292 trix and provide biomechanical properties to connective tissues.

293 hole, governs ectopic mineralization in soft connective tissues.

294 sparsely in the stroma of subcutaneous loose connective tissues.

295 anding control of collagen mineralization in connective tissues.

296 ate, highlighting the effect of succinate on connective tissues.

297 tion of multiscale force transmission within connective tissues.

298 ition of calcium phosphate complexes in soft connective tissues.

299 ms a distinct microfibrillar network in most connective tissues.

300 he bulk of the extracellular matrix (ECM) in connective tissues.