ライフサイエンスコーパス: connexin 32

1 observed when the mutant is expressed before connexin 32.

2 chimeras with the transmembrane portions of connexin 32.

3 -3, claudin-1, -2, -4, and -8, occludin, and connexin-32.

4 Connexin-32 abundance was higher (P<0.05) in cerebral co

5 itivity of gap junction channels composed of connexin 32 and decreases their sensitivity to transjunc

6 Connexin-32 and connexin-43 are among the most abundant

7 Western immunoblot was used to measure connexin-32 and connexin-43 expression in cerebral corti

8 We examined the effects of ontogeny on connexin-32 and connexin-43 protein abundance in cerebra

9 We conclude that (1) connexin-32 and connexin-43 protein are expressed early

10 nd expressed the hepatocyte-specific markers connexin-32 and hepatic nuclear factor-4alpha, but not c

11 Purified homomeric connexin-32 and heteromeric connexin-32/connexin-26 chan

12 ecular permeation through channels formed by connexin-32 and/or connexin-26 reconstituted into liposo

13 ension native calmodulin, must interact with connexin 32 before gap junctions are formed.

14 ff limits for permeability through homomeric connexin-32 channels and through heteromeric connexin-32

15 t does not occur significantly for homomeric connexin-32 channels.

16 nd cGMP were permeable through the homomeric connexin-32 channels.

17 imately 420 nM) were twice those measured by connexin-32 chimera (approximately 200 nM); both chimera

18 A rat connexin 32 clone was used to isolate a single partial c

19 rified homomeric connexin-32 and heteromeric connexin-32/connexin-26 channels were inhibited by expos

20 connexin-32 channels and through heteromeric connexin-32/connexin-26 channels.

21 In Schwann cells, connexin 32 (Cx32) can oligomerize to form intracellular

22 nating neuropathy caused by mutations in the connexin 32 (Cx32) gene.

23 disease family with a novel mutation in the Connexin 32 (Cx32) P2 promoter region at position -526bp

24 Connexin 32 (Cx32), a gap junction protein, is found wit

25 We demonstrate that connexin 32 (Cx32), a key hepatic gap junction protein,

26 n the gene encoding the gap junction protein connexin 32 (Cx32), which is expressed by Schwann cells.

27 rm of X-linked CMT is caused by mutations in connexin 32 (Cx32).

28 patients with mutations in the gene encoding connexin 32 (Cx32).

29 n the gene encoding the gap junction protein connexin 32 (Cx32).

30 hypothesis that the gap junctional proteins connexin 32 (Cx32; expressed by oligodendrocytes, intern

31 Madin-Darby canine kidney cells expressing connexin-32 (Cx32) and Cx43 were exposed to bradykinin (

32 eral myelin protein 22, myelin protein zero, connexin 32, early growth response factor 2, periaxin, m

33 nic increases in protein abundance, whereas, connexin-32 exhibited reciprocal decreases in abundance

34 The relationship between the loss of connexin 32 function and clinical manifestations of X-li

35 ne, early growth response gene 2 (EGR-2) and connexin-32 gene, which are expressed in Schwann cells,

36 The carboxyl terminus (CT) of connexin 32 has been reported to be required for the ope

37 ntain low amounts of connexin 26 relative to connexin 32 in contrast to the equal connexin ratios det

38 ied that increased levels of glutaminase and connexin 32 in Mecp2-null microglia are responsible for

39 reviously that expression of connexin-43 and connexin-32 in an indolent prostate cancer cell line, LN

40 pendent state, we introduced connexin-43 and connexin-32 into an invasive, androgen-independent cell

41 In addition, other sequence elements of the connexin-32 IRES were characterized by mutation analysis

42 Connexin-32 is expressed primarily in oligodendrocytes a

43 RES was essential for the translation of the connexin-32 mRNA in nerve cells.

44 When the 5'-UTR of nerve-specific connexin-32 mRNA was inserted between the two genes of a

45 slated region (5'-UTR) of the nerve-specific connexin-32 mRNA, previously found in a family with Char

46 y site (IRES) in the 5'-UTR of the wild-type connexin-32 mRNA.

47 17p12 duplication (CMT1A duplication), 11 a connexin 32 mutation, 5 a myelin protein zero mutation,

48 reviously unreported mutant alleles: two for connexin 32, three for myelin protein zero, and two for

49 porter Npt2b, and the gap junction component connexin 32, usually expressed in secretory epithelia, w

50 and in acutely dissociated cells showed that connexin 32 was expressed in neurons and oligodendrocyte

51 rved cysteines in the extracellular loops of connexin 32 were moved individually and in all possible