ライフサイエンスコーパス: consequence

1 QTLs and illuminate the underlying molecular consequence.

2 tations and analyzed the resulting molecular consequences.

3 ectivity filter often have severe functional consequences.

4 cost savings but also to negative downstream consequences.

5 of cancer development through its mutagenic consequences.

6 ect a wider range of potential environmental consequences.

7 little chance of inducing unintended adverse consequences.

8 ine development have had unintended negative consequences.

9 iment element composition and its ecological consequences.

10 th negative environmental and socio-economic consequences.

11 c electromagnetic fields may have biological consequences.

12 l populations and may have important fitness consequences.

13 les, and abrogating multimers has pathogenic consequences.

14 rinking, alcohol craving, or alcohol-related consequences.

15 ous diseases with public health and economic consequences.

16 otentially severe mental and physical health consequences.

17 single, individual cells can have important consequences.

18 upling exists and investigate its phenotypic consequences.

19 or too much iron can have important clinical consequences.

20 ness and the understanding of climate change consequences.

21 acological therapy has reduced these harmful consequences.

22 al differences with significant pathological consequences.

23 neurons in selecting actions based on their consequences.

24 ty occur as we age, and are there functional consequences?

25 As a consequence, a significant body of work now exists on th

26 As a consequence, a single peptide can act through several me

27 sease as well as determining the hemodynamic consequences and extent of ventricular remodeling, which

28 ecurrent mutations in cancer with functional consequences and that the mutations occur at similar fre

29 We report that as a consequence AR variants lacking the LBD cannot be ubiqui

30 The consequences are explored for removal of TFA from the at

31 issue loss as well as its systemic metabolic consequences are far less understood.

32 ajor cause of human disease and the cellular consequences are highly complex.

33 aunation can be severe, but the evolutionary consequences are nearly unknown because it remains uncle

34 These consequences are the precisely goals of therapeutic inte

35 enteric RNA viruses, but the mechanisms and consequences are unclear.

36 espite recent progress, the full spectrum of consequences as a result of KCNQ2 dysfunction in neocort

37 se modifications have significant functional consequences as indicated by profoundly higher deformati

38 juana may help some, cannabis-related health consequences associated with changes in state marijuana

39 habitat at these times could lead to adverse consequences at the population level.

40 posure to low Ag-density RBCs is not without consequence, because recipients subsequently develop Ag-

41 patocyte proliferation and often has adverse consequences (development of cirrhosis or liver cancer).

42 As a consequence, dysfunction of these processes in adipose t

43 Research on the long-term consequences emphasises that, for many patients, TBI sho

44 of Langherans, and for multiple pathological consequences encountered by patients suffering from type

45 incidence, mortality, and survival, and the consequences, especially in socioeconomically disadvanta

46 Range expansion has genetic consequences expected to result in differentiated wave-f

47 asonal first-year ice cover with significant consequences for Arctic primary production.

48 egetation at the global scale, with negative consequences for both provisioning and climate regulatin

49 ay inadvertently produce substantial adverse consequences for cocaine addiction.

50 This result has important consequences for computational models of reinforcement l

51 mphetamine use poses potentially devastating consequences for directly affected individuals and for s

52 rm genetic discovery, explore the phenotypic consequences for disease-associated variants, and test c

53 drift on bear movements, and we modeled the consequences for energy demands of adult females in the

54 ucleotides during DNA replication has severe consequences for genome stability.

55 stem processes, whereas others have dramatic consequences for human and ecosystem health.

56 egulating these pathways might have dramatic consequences for human health.

57 nfection of nonneuronal cells, with distinct consequences for infectivity in different cell types.

58 hracis, in a tropical rainforest have severe consequences for local wildlife communities.

59 socioeconomic status (SES) can have negative consequences for long-term health.

60 depolarization susceptibility with important consequences for neuroinflammation and trigeminovascular

61 poral variability of these hotspots, and the consequences for nitrogen processing, is still hindered

62 tention paid to its global prevalence or its consequences for patients and populations.

63 ublic health problem, often with devastating consequences for patients and their families.

64 ild vertebrate populations and has important consequences for population and evolutionary dynamics.

65 class of vdW-DF functionals, with particular consequences for predicting material functionality acros

66 y subsets of atoms, which can have important consequences for structure-property relationships in the

67 These results have important consequences for the analysis and design of novel magnet

68 e C-terminal or transmembrane segments, with consequences for the assembly, surface expression, and f

69 tand the functional significance and fitness consequences for the beetle of mite-associated changes t

70 , leading to serious economic and ecological consequences for the maritime and aquaculture industries

71 cific salmon for reproduction, with negative consequences for the substantial economic, cultural, and

72 pressures on their offspring with important consequences for their phenotypic and genetic diversity.

73 Climatic modification of LSWT has numerous consequences for water quality and lake ecosystems, so q

74 n resistance in obesity may have unfavorable consequences for whole-body glucose homeostasis.

75 The ecohydrological consequences from the 2016 drought are more severe and e

76 tion and symptoms of schizophrenia, and as a consequence generate new hypotheses that are testable in

77 As a consequence, heterogeneous classical nucleation theory c

78 As a consequence, HVEM-deficient recipients failed to afford

79 sis of adult pulmonary TB may have different consequences in different clinical settings.

80 xity of hepatic responses and their systemic consequences in other organs.

81 effects may result in downstream phenotypic consequences in sudemycin-treated mutant cells.

82 with regards to predation protection but has consequences in terms of energy allocation.

83 xtracted from the multiplex may have serious consequences in the characterization of the true robustn

84 d defective efferocytosis and its pathologic consequences in the thymus after dexamethasone treatment

85 ecreased cardiac output, whereas ventilatory consequences include increased airway pressures, hyperca

86 Different legal consequences, including greater punishments, are mandate

87 g disorders may have adverse cardiometabolic consequences, including overweight or obesity and high b

88 associated with serious short- and long-term consequences, including re-intubations, ICU readmissions

89 r symptoms in PD and have important clinical consequences, including therapeutics.

90 HBV reactivation with its potential consequences is particularly a concern when these people

91 As a consequence, it is possible that collagen-binding cells

92 As a consequence, many human leukemias and other hematologic

93 As a consequence, nanoscale characterization of the membrane

94 As a consequence, NDC80 expression is repressed during meioti

95 tically initiated from the grain interior, a consequence of a dislocation-based crack incubation mech

96 The anomalous exothermal peak is the consequence of a polyamorphous phase transition between

97 hin a single p-orbital manifold as a general consequence of a trigonal crystal field, and as such can

98 at global protein synthesis is elevated as a consequence of activated nucleoli and enhanced ribosome

99 allergies observed in human subjects as the consequence of allergen exposures that recurrently activ

100 inding site is eliminated in AhCSD1-2.2 as a consequence of alternative splicing, which bypasses miRN

101 unction and survival may be compromised as a consequence of an incomplete islet BM, which has implica

102 59 60 References 61 As a consequence of an increase in world population, food dem

103 ing pancreatic beta cells are destroyed as a consequence of an inflammatory process initiated by lymp

104 ost-Start cell-cycle periods rather than the consequence of an underlying molecular mechanism measuri

105 A common consequence of becoming nonphotosynthetic is the reducti

106 s in the natural environment, primarily as a consequence of biological synthesis and oil spills.

107 of immune cells in the duodenal mucosa as a consequence of both adaptive and innate immune responses

108 ether such dynamic coupling is impaired as a consequence of brain aging in later life, contributing t

109 eoplastic activity mostly (if not only) as a consequence of cancer cell-intrinsic effects.

110 Here, we test the consequence of centrosome amplification by creating mice

111 rated in contaminated groundwater sites as a consequence of chemical degradation of trichloroethene (

112 elative spleen weight, which is a documented consequence of chronic stress in chickens.

113 ulic acid accumulation but was (largely) the consequence of collapsed vessels.

114 gations revealed that this effect is not the consequence of conformational changes in the catalyst bu

115 the increased prevalence of asthma may be a consequence of decreased intake of antioxidant nutrients

116 egree of supercooling, but was found to be a consequence of differences in the crystallisation behavi

117 This dietary variation may be a consequence of different competitive pressures.

118 ective Ab titers against S. aureus was not a consequence of diminished formation of B cell memory; in

119 enetic information can also be modified as a consequence of disrupting processive DNA replication.

120 Suppression of TH2 immunity can occur as a consequence of either deletion or anergy of antigen-spec

121 nce the distribution of products formed as a consequence of electrostatic interactions between solvat

122 (lo) Tregs and was shown, in part, to be the consequence of exposure to IL-12.

123 ity of some HIV-specific CD8(+) T cells is a consequence of factors in addition to TCR sequence that

124 the decreased mitochondrial biogenesis is a consequence of FXN deficiency.

125 To date, the fiscal consequence of hospital variation for autologous free fl

126 As a consequence of increased FA oxidation and reduced PPARal

127 Dark state as a consequence of interference between different quantum st

128 As a consequence of ISVP-to-ISVP* conversion, neighboring mu1

129 A consequence of linear models is that faster translation

130 rictures were considered to be an inevitable consequence of long-term inflammation in patients who di

131 Thus, in these cells, the cellular consequence of MOR desensitization cannot be defined by

132 yet its role in altering brain function as a consequence of neuroinfectious disease remains unclear.

133 y-defined recognition motif, apparently as a consequence of non-specific electrostatic interactions,

134 that defective ATM-mediated DNA repair is a consequence of P62 accumulation, which impairs H2A ubiqu

135 Bronchopulmonary dysplasia (BPD), the main consequence of prematurity, has a significant heritabili

136 The ultimate consequence of quantum many-body physics is that even th

137 hese phenotypes, confirming that they were a consequence of reduced ABA levels.

138 One consequence of rising spring temperatures is that the op

139 e intimate understanding of the response and consequence of rotating ligands integrated into porous m

140 imply as molecular function; rather, it is a consequence of spatial location, expression timing, and

141 This is partly a consequence of specific hurdles related to the large siz

142 H dependence in the physiological range as a consequence of the atypically high pK values of the phos

143 A consequence of the DNA internal motion is that protein t

144 that the high reactivity at these sites is a consequence of the formation of sigma-holes, i.e., maxim

145 As a consequence of the global rise in the prevalence of adol

146 on of whether social diversity may also be a consequence of the harsh environment within which we fin

147 anchored to microcantilevers that occur as a consequence of the hybridization.

148 We prove that nodes are a consequence of the orthorhombic crystal structure.

149 y determined both, in vitro and in vivo as a consequence of the transient CD44 overexpression induced

150 and PTPIP51 manipulation on autophagy are a consequence of their ER-mitochondria tethering function.

151 ults highlight the importance and functional consequence of these mutations and provide an important

152 The functional consequence of this diet will now be tested in a clinica

153 A consequence of this greater increase in pCa50 at short S

154 To determine the functional consequence of this HDAC6-regulated phosphorylation even

155 A consequence of this reduced microtubule turnover is dimi

156 We investigated the biological consequence of this RI and demonstrate that its inclusio

157 neoplasms are a potentially life-threatening consequence of treatment for autoimmune disease (AID) an

158 ure silicon solidified in silica as a direct consequence of volume-constrained solidification of a ma

159 can successfully compensate for the adverse consequences of a complicated postoperative recovery.

160 ications at preventing the adverse metabolic consequences of a high fat diet.

161 We investigated the extent, causes and consequences of a hybrid zone between Anopheles coluzzii

162 Here, we have elucidated the functional consequences of a NaV1.9 mutation (L1302F) that is assoc

163 The consequences of a permanent expression of these genes ar

164 To test the functional consequences of Ab fucosylation, we produced V-gene-matc

165 Limiting the debilitating consequences of ageing is a major medical challenge of o

166 r mild conditions, we observe the macroscale consequences of amphiphilic polymer synthesis and the re

167 By investigating the immediate consequences of aneuploidy on cell physiology, we identi

168 To understand the cellular and organismal consequences of aneuploidy, it is important to determine

169 of using this approach in understanding the consequences of anthropogenic environmental change on na

170 Limited research has quantified the genetic consequences of assortative mating.

171 te the efficacy, efficiency, and physiologic consequences of automated, endpoint-directed resuscitati

172 Here, we examined the mechanism and consequences of AXR1 neddylation in more detail.

173 understanding how predictions of the sensory consequences of behavior may be generated in other senso

174 d motor behavioral tests to characterize the consequences of bifacial maps in the thalamocortical sys

175 and defective cell morphology are secondary consequences of bulky cargo retention.

176 eck limiting understanding of mechanisms and consequences of cell death in complex organisms is the i

177 These studies reveal distinct consequences of changes in telomerase repeat addition pr

178 The consequences of chronic insufficient sleep for health re

179 mechanisms underlying the neurodegenerative consequences of CISD2 mutations and the subsequent devel

180 As the consequences of climate change are becoming evident, cli

181 Here we interrogate the molecular consequences of CRISPR/Cas9-mediated deletions at 17 sit

182 These results reveal unanticipated consequences of delaying CRY degradation, indicating tha

183 No typical symptoms or classic consequences of diagnosed celiac disease (diarrhea, anem

184 These negative functional consequences of disinhibition may include reduced workin

185 However, the clinical consequences of disruption of this complex remain largel

186 as a model for investigating the repair and consequences of DNA crosslinks in metazoan development a

187 s target human GADD45B to protect cells from consequences of DNA damage, which can be triggered by vi

188 cy were performed to identify the functional consequences of enhanced PPARgamma expression.

189 which aim to reduce the unacceptable harmful consequences of excess alcohol consumption, obesity, and

190 ut the long-term cognitive and mental health consequences of exposure to football-related head trauma

191 dented resource to study the gene expression consequences of expressing short hairpin RNAs (shRNAs).

192 ntified sources, barriers to addressing, and consequences of fatigue.

193 The consequences of fibroblast-specific Smad3 loss were not

194 ore used to anticipate the potential genetic consequences of future warming.

195 Additionally, we assess the phenotypic consequences of genomic copy-number alterations that are

196 ritical for understanding and predicting the consequences of global change over evolutionary and ecol

197 irectly visualize and investigate functional consequences of GPCR-mediated signaling at the Golgi/tra

198 sms by uniting hypotheses for the causes and consequences of habitat selection and dispersal across s

199 istic predator-predator interactions and the consequences of heterogeneity in herbivore body size and

200 y not be related to other pathophysiological consequences of HF.

201 oskeletal components and demonstrate the key consequences of HIs for the mechanics of pronuclear migr

202 onomic theory and are often described as the consequences of ignorance, irrationality or specific bia

203 on of each N-glycan site, but the structural consequences of individual N-glycan site on integrin act

204 enal tubular response to IRI that limits the consequences of inflammation, a key process in the devel

205 Understanding the consequences of integration for the evolution of the vir

206 Consequences of its loss include neurofilament network a

207 tanding of the hemodynamic and physiological consequences of laparoscopic surgery as well as a define

208 Consequences of LCS include a reduced rate of decline of

209 However, the consequences of loss of Lpd in the CNS on behaviour are

210 One of the main consequences of mean sea level rise (SLR) on human settl

211 ble immunologic mechanisms behind causes and consequences of microbial dysbiosis in CVID.

212 to motivate our study of the epidemiological consequences of modular structure in animal societies.

213 Despite these differences, the consequences of more versus less frequent biopsies seem

214 movements, indicating that predicted sensory consequences of motor commands cancel sensory signals.

215 fusion protein (hexameric-Fc) and tested the consequences of multi-valent Fcgamma-receptor engagement

216 erologous expression systems, the functional consequences of mutant channels have not been thoroughly

217 mplications for understanding the causes and consequences of N limitation in coupled nutrient cycles,

218 precludes a comprehensive assessment of the consequences of non-coding variation.

219 ve important implications for the functional consequences of noncoding transcription.

220 ever, the neuronal mechanisms and behavioral consequences of NRG3-ErbB4 sensitivity to nicotine remai

221 e numerous studies have addressed causes and consequences of obesity-related adipose tissue hypertrop

222 ommands to predict and attenuate the sensory consequences of our movements.

223 We outline some experimental consequences of our results.

224 -seq; and (iii) morphological and functional consequences of PLAG1 deficiency by determining testicul

225 is using X-gal staining; (ii) transcriptomic consequences of PLAG1 deficiency in knock-out and hetero

226 akes it a prime system in which to study the consequences of plant-pathogen interactions on fertility

227 for more in-depth analysis of the functional consequences of promoter region variation within the cla

228 n targeted downstream pathways to ameliorate consequences of protein dysfunction; however, targeting

229 of the most surprising and counter-intuitive consequences of quantum mechanics, with potent applicati

230 previous genetic analysis and highlights the consequences of redundancy and synergy during informatio

231 expression analysis to assess the functional consequences of rs641738 on hepatic MBOAT7 expression.

232 ection, we have little information about the consequences of seasonal fitness trade-offs for populati

233 Health consequences of sexually transmitted diseases disproport

234 yond doubt that treatment reduces the severe consequences of soil-transmitted helminthiasis.

235 iewed here, with an emphasis on the clinical consequences of splicing factor mutations, mechanistic i

236 se characteristics for the behavioral health consequences of spousal loss.

237 mice recapitulates multiple neurobehavioral consequences of stressor exposure, including long-lastin

238 re summarizing some of the known or reported consequences of such infection during pregnancy.

239 duals and sheds light on possible phenotypic consequences of such variation on complex traits and dis

240 e findings highlight the unintended negative consequences of supplemental folic acid.

241 nt to better understand the gene and genomic consequences of surviving at extremely small population

242 Although the consequences of the cross-talk between M1 and NK cells a

243 To assess the consequences of the intracellular Zn(2+) accumulation, w

244 d from the SCOPE (Observational Study of the Consequences of the Protease Inhibitor Era) cohort, a cl

245 the fission yeast ring to explore essential consequences of the recently discovered ring ultrastruct

246 s equally essential to avoid the undesirable consequences of their accumulation and disintegration.

247 By contrast, observers that experience the consequences of their actions improve performance based

248 sic function of proteins and the deleterious consequences of their misfolding.

249 t phases of population fluctuations, and the consequences of these changes for both trait and populat

250 efenses and nutritive quality as well as the consequences of these changes for the behavior and fitne

251 ents genome wide and ectopic transcriptional consequences of this binding.

252 Investigating the consequences of this challenge, we have characterized C.

253 The ecological consequences of this defaunation can be severe, but the

254 Here, we consider the consequences of this for schistosome biology, immunoepid

255 ve in potentially eliminating the arrhythmic consequences of this genetic disease.

256 It is currently unclear how the consequences of this genetic insult unfold to impair neu

257 urface-displayed adhesin, and until now, the consequences of this interaction were unknown.

258 mes associated with ADP-ribosylation and the consequences of this PTM on substrates.

259 To assess the functional and biochemical consequences of this variant, we generated transgenic ze

260 The timing and consequences of TPMs have not been fully established.

261 ural mechanisms that underlie the behavioral consequences of transcranial alternating current stimula

262 We discuss the consequences of trawling for the impacted communities as

263 However, little work explores the fitness consequences of variation in behavior within individuals

264 to energy intake, we explored the causes and consequences of variation in body mass of wild female Sv

265 No toxicity or adverse immune consequences of vector administration are observed.

266 es are capable of gene delivery, however the consequences of vesicle-mediated transfer on the pattern

267 We theoretically explore consequences of warming for predator-prey dynamics, broa

268 to predict, and often suppress, the sensory consequences of willed movements.

269 Its consequence on the structure and function of cortical ne

270 ndividuals can have profound and predictable consequences on community assembly, its role in the asse

271 ress is known to alter health, its long-term consequences on mortality remain largely unknown.

272 ave different temporal onsets and functional consequences on neural activity and behavior.

273 oteins associate with mitochondria and their consequences on OXPHOS.

274 red between AtPMEI4 and AtPMEI9 had distinct consequences on pollen tube elongation.

275 ersus cytosolic actin assembly and resulting consequences on protrusion.

276 melanosomal morphology may potentially have consequences on the ability of the cells to perform anot

277 Immunogenicity can have devastating consequences on the safety and efficacy of therapeutic p

278 t-forming species such as seagrasses, as the consequences on their abundance will cascade throughout

279 valence, little is known about its potential consequences on visual function.

280 As a consequence, oxygen consumption rates and intracellular

281 mix experience with appetitive and aversive consequences, parallel memories are established in a way

282 s) and undesirable (i.e., harms and burdens) consequences, patient values and preferences, cost, and

283 As a consequence, PNPLA1-deficient mice lacked a functional c

284 ion derived from allele frequency databases, consequence prediction algorithms, or genomic datasets c

285 pared their transcriptomes to understand the consequences related to the observed elevated 12-oxo phy

286 em have been described, but their functional consequences remain largely unexplored.

287 As a consequence, stratospheric chlorine levels are declining

288 Neuronal injury often leads to devastating consequences such as loss of senses or locomotion.

289 ic risk to produce negative long-term health consequences such as neurodegenerative disease.

290 As a consequence, the enzyme significantly increased its capa

291 cid units within the hydrogel scaffold; as a consequence, the hydrogel framework collapses resulting

292 As a consequence, the number of active genes in hybrids excee

293 As a consequence, the reaction dynamics are no longer exponen

294 As a consequence, the use of handheld echocardiography is on

295 phenomenon and (ii) highlight an unexpected consequence: the self-diffusion coefficient of the catio

296 As a consequence, these cytoskeletal networks failed to suppo

297 As a consequence, this channel acts like a "ghost" of the lim

298 d R1150Q/R1150W) and investigated functional consequences using macroscopic rubidium ((86)Rb(+)) effl

299 Functional consequences were investigated by RNA studies and on the

300 erstanding of innate allorecognition and its consequences would provide essential insight into allogr