ライフサイエンスコーパス: consequential

1 nges in body composition that are common and consequential.

2 indexes were small and likely not clinically consequential.

3 effect on implosion dynamics is potentially consequential.

4 e of a metazoan precursor miRNA (pre-miRNA), consequential 5' heterogeneity, newly identified instanc

5 first evidence that CD38 expression and the consequential accumulation of cADPR play a causal role i

6 id 1151-1154 of BRCA1 abolished cleavage and consequential accumulation of the BRCA1 C-terminal fragm

7 therwise enable ERK2 phosphorylation and the consequential activation of an NF-kappaBeta response.

8 ion of PRL-3-driven EGFR hyperactivation and consequential addiction to EGFR signaling opens new aven

9 1 and monocyte chemotactic protein-1 and the consequential adhesion of monocytes to ECs.

10 tion observed specifically near functionally consequential amino acid substitutions.

11 ever, experimental observations have shown a consequential and consistent departure from an exponenti

12 essed in tumor, indicating the presence of a consequential antigen cascade.

13 l produced from sugar cane in Brazil under a consequential approach.

14 and are applicable to both attributional and consequential approaches to LCA.

15 in cells they repress protein output without consequential Argonaute-catalyzed cleavage.

16 ratic mutations appear to be as functionally consequential as recurrent mutations.

17 nessing violence toward siblings would be as consequential as witnessing violence toward mothers.

18 Since glucose metabolism and the consequential ATP production are depressed in the tempor

19 led to the metanephric dysmorphogenesis and consequential atrophy of the mesenchyme exhibiting accel

20 of IAPP in vivo, which are expected to have consequential bearings on IAPP glycemic control and T2D

21 (HL-525), thus revealing transcriptional and consequential biochemical changes that may be required f

22 As a highly consequential biological trait, a memory "bottleneck" ca

23 Pathway associations are especially consequential, but existing algorithms are demonstrably

24 in carbon-supported palladium catalysts with consequential changes in hydrogenation performance.

25 directly to interference with endocytosis or consequential changes in proliferation and signaling.

26 e current rapid increase in connectivity and consequential changes in the structure of human, agricul

27 resulted in systemic vascular leakage and a consequential collapse of the circulatory system.

28 beliefs and to the decisions they make in a consequential context.

29 ace violence towards nurses is prevalent and consequential, contributing to nurses' reduced health an

30 somal storage and autophagy dysfunction with consequential cytoplasmic accumulation of autophagic sub

31 bunit nanoparticle spawns a slightly tilted, consequential 'daughter' nanoparticle, which by amplific

32 ctivation of PCNA gene expression by Tax and consequential decrease in nucleotide excision repair med

33 DNA bulges are biologically consequential defects that can arise from template-prime

34 ing region on the Y chromosome (NRY) and the consequential degeneration of genes trapped in the NRY [

35 deletion of MAGL causes tonic activation and consequential desensitization of CB(1) receptors.

36 e for many vertebrate neural circuits ignore consequential detail.

37 e for many vertebrate neural circuits ignore consequential detail.

38 f atheroprone endothelial phenotypes and the consequential development of atherosclerotic lesions.

39 ture, similar to the human ortholog but with consequential differences.

40 er health care professionals, and inaugurate consequential discourse with the public about health car

41 Mastitis, the most consequential disease in dairy cattle, costs the US dair

42 death during embryonic limb development and consequential disturbance of limb outgrowth.

43 up-regulation of epidermal growth factor and consequential down-regulation of Capicua, which is an AT

44 be caused by chronic T-cell activation and a consequential DUSP4-dependent dampening of TCR signaling

45 differences in tissue expression in vivo and consequential effects on blood pressure stemming from th

46 mining drug pharmacokinetics in vivo and the consequential effects on drug absorption distribution, m

47 immune cells, largely driven by IL-1 and its consequential effects on IL-23 secretion.

48 enced by the tumor microenvironment, and its consequential effects on melanoma malignancy remain unch

49 des and systematic deletions of p14ARF, with consequential effects on p53 stabilization and transcrip

50 Interestingly, sisR-1 represses ASTR, with consequential effects on rga pre-mRNA expression.

51 We have also studied the consequential effects on the renin angiotensin system an

52 and foot compared with younger animals, with consequential effects on the whole-animal physiological

53 perturbation of the IR recycling pathway and consequential enhancement of the IR signaling cascade.

54 se epigenomics is distinguishing causal from consequential epigenetic variation.

55 that elaboration of a mutator phenotype is a consequential event in breast cancer and suggest that a

56 memory" to describe the recall of shocking, consequential events such as hearing news of a president

57 he processing of incised cross links and the consequential failure to initiate recombinational repair

58 cular function and uterine hemodynamics with consequential fetal ischemia.

59 ain size, rendering the effects increasingly consequential for big brains.

60 thermore, we find that these differences are consequential for downstream analyses such as determinat

61 of earnings inequality that is arguably most consequential for the "other 99 percent" of citizens: th

62 lular entry mechanisms in RCC and are highly consequential for the development of viral antitumor age

63 nteractions and subsequent activities may be consequential for the pathogenesis of AD.

64 recombinant gB or gD vaccines and may not be consequential for vaccine development.

65 eneration of intracellular asymmetry and the consequential formation of the multicellular body patter

66 report on their likelihoods of carrying out consequential future behaviors, including complying with

67 g the numeral abnormality of centrosomes and consequential genomic instability associated with loss o

68 alth inequalities represent perhaps the most consequential global health challenge and yet they persi

69 nicity of the Caribbean CNR20235 isolate and consequential host immune responses in mice.

70 arly learning, when concept updating is most consequential, HPC is functionally coupled with prefront

71 t interfered with everyday activities but no consequential impairment of object usage or face recogni

72 ompromised development of the structure with consequential impairments in memory function.

73 f both visual and auditory information, with consequential implications for our decisions.

74 ons in permeability can only be biologically consequential in contexts where the diffusional path of

75 buffers, the change in pH over 3 kbar may be consequential in highly pH-sensitive biochemical systems

76 Iron deficiency anemia is common and consequential in nondialysis-dependent CKD (NDD-CKD).

77 orking memory and attention may be much less consequential in patients with dystonia than has been re

78 ing of different neurons may be particularly consequential in sparsely firing neural populations such

79 ng that these tiny molecules, so diverse and consequential in their biological functions, have been h

80 this likely occurs is through oxidation and consequential inactivation of cellular phosphatases.

81 pregulated in response to low heart rate and consequential increased stroke volume.

82 n through inhibition of let-7 maturation and consequential induction of BLIMP1.

83 TLRs, Rig-I, Dectin-1) within APCs, with the consequential induction of CD1d-mediated Ag presentation

84 d to ablated first-phase insulin release and consequential insufficient insulin secretion in vivo, wi

85 How large a treatment effect has to be to be consequential is a matter for clinical judgment.

86 Less practical, but perhaps ultimately more consequential, is the impact of neuroscience on our worl

87 practice for GTW and could be excluded with consequential LCA system boundaries.

88 Using a policy-based consequential LCA, we find that the lifecycle emissions

89 mated from a market-based allocation used in consequential LCA.

90 hold cases and shows that the combination of consequential legitimacy (a moral understanding of outco

91 based modeling (ABM) as a novel approach for consequential life cycle assessment (C-LCA) of large sca

92 Our approach is motivated by consequential life cycle assessment (CLCA) and aims to c

93 Discussions on Consequential Life Cycle Assessment (CLCA) have relied l

94 ity of bioenergy production in Denmark, this consequential life cycle assessment (LCA) evaluated the

95 This consequential life cycle assessment (LCA) evaluated the

96 e uses a market-based allocation method in a consequential life cycle assessment (LCA) framework to e

97 A consequential life cycle assessment (LCA) is conducted t

98 Collectrin is a consequential link between the transport of l-arginine a

99 quences (e.g., the promoter) as functionally consequential, long-read sequencing revealed that this s

100 per highly sensitized patient, with a small consequential loss of 0.005 quality-adjusted life-years

101 deficits in prefrontal cortical function and consequential loss of inhibitory control could be crucia

102 its inhibition of oncogenic Src activity and consequential loss of nuclear beta-catenin, activities t

103 lead to alteration of dendritic spines with consequential major pathological changes in brain functi

104 phorylation is an efficient and biologically consequential mechanism in GISTs.

105 ls, supporting the notion that the UPR was a consequential mechanistic pathway affected by thiopyrano

106 ) according to the likelihood of a resultant consequential medical event if a critical intervention i

107 ions with a likelihood of association with a consequential medical event if withdrawn, ranging from 3

108 The upper limit of risk tolerance for a consequential medical event in the lowest risk group if

109 ification system, assign risk tolerance of a consequential medical event to each category, identify c

110 the basis of risk tolerance for a subsequent consequential medical event.

111 The findings indicate consequential medication access problems for psychiatric

112 BLR1 knock-out cells failed to show RAF and consequential MEK and ERK phosphorylation, failed to acc

113 a AFP, including stereo-specific binding and consequential melting and freezing inhibition.

114 These results imply that consequential miRNA-mediated repression is largely irrev

115 o rectify other, nonobvious (yet potentially consequential) mistakes after a paper's publication.

116 Centrosome hyperamplification and the consequential mitotic defects contribute to chromosome i

117 st strategically positioned and behaviorally consequential modulatory systems of the human cerebral c

118 rch community finds itself at a particularly consequential moment.

119 usage of an intermediate promoter site, with consequential monoallelic LMO2 overexpression.

120 icantly reduces the bacterial burden and the consequential morbidity and mortality during experimenta

121 ele, when homozygous or combined with a more consequential mutation like C294Y, leads to hepatic iron

122 The implied consequential occurrences were ultimately better outcome

123 attributes of best practice, antecedent and consequential occurrences, variations, and empirical ref

124 A second module, consequential of trauma exposure, contained PTSD resilie

125 orbidity, and whether the association may be consequential or causal, in a sample of almost two milli

126 cordant and may non-specifically reflect the consequential or downstream effects of IEDs on brain act

127 Ialpha is a key mediator of hypotension and consequential organ injury during sepsis.

128 stranded DNA structure, the flap, is not the consequential outcome.

129 er understand why personality traits predict consequential outcomes, which calls for a closer look at

130 associations reflect both likely causal and consequential pathways of the disease.

131 nity discovery of environmental exposure and consequential processes.

132 al variation is a potentially ubiquitous and consequential property of animal populations.

133 Thus, important attitudes are real and consequential psychological forces, and their study offe

134 ons, has the potential to yield high-impact, consequential public health insights.

135 t closely to the genetic abnormality and the consequential reduction in frataxin protein.

136 stant high levels of low frequency sound and consequential reduction in the communication space obser

137 ts will lead to downregulation of BAFF and a consequential reduction of autoreactive B cell clones an

138 n-aptamer supramolecular cross-links and the consequential reduction of excluded volume in the hydrog

139 sed to remove subgingival deposits, yielding consequential reductions in gingival inflammation and pr

140 and the validity of the results, while the "consequential" reflects the practical application of the

141 fore necessary to understand the control and consequential regulatory activity of the Runx2 gene with

142 organizing the research literature, numerous consequential relations are identified.

143 ct is relatively weak, such that by the time consequential repression ensues, the effect of mRNA dest

144 via nonselective pores induced by P2X7R with consequential repression of caspase-1-mediated processin

145 of the catabolite control protein (CcpA) and consequential repression of catabolic regulons.

146 uced reprogramming of tRNA modifications and consequential reprogramming of ribosomes in translationa

147 th the burgeoning problem of obesity and the consequential rise in bariatric surgery, uncertainty rem

148 -induced regulation of eCB signaling and the consequential role changes in eCB signaling have with re

149 that weather patterns during seemingly less consequential seasons (e.g., winter precipitation) can h

150 The consequential shift in focus from single-gene variants t

151 ally explains TGF-beta receptor dynamics and consequential signaling diversity-related gene expressio

152 a functional dimer; however, details of the consequential significance and structural requirements t

153 tions to estimate the number of functionally consequential single-nucleotide polymorphisms (SNPs) car

154 subventricular zone (SVZ) is a frequent and consequential site of pediatric and adult glioma spread,

155 e face system has important implications for consequential situations such as eyewitness identificati

156 People make rapid and consequential social judgments from minimal (non-emotion

157 location decisions, and of at least the most consequential specific decisions, can promote transparen

158 complex/C ubiquitin ligase activity and the consequential stabilization of the CDH1 targets such as

159 o the delta-cells via gap junctions, and the consequential stimulation of somatostatin secretion inhi

160 nduces IL-13Ralpha2 expression, leading to a consequential suppression of responsiveness to IL-13.

161 cts on synchrony may well be more common and consequential than previously recognized.

162 e to the discussion on how to operationalize consequential thinking in LCA practice.

163 lement are dominated by environmental risks, consequential to ecosystem transformations that promote

164 m and hypothermia in endotoxic shock are not consequential to hypoxia but serve as a pre-emptive stra

165 ermia instead of fever in endotoxic shock is consequential to hypoxia.

166 is not causal to dyslexia but may instead be consequential to impoverished reading.

167 ctly by facilitating STAT1 dephosphorylation consequential to increased STAT1 solubility because of s

168 whether modifications in the N-terminus are consequential to MYH function, we overexpressed intact a

169 not yet known whether cortical resonance is consequential to neural oscillations or an emergent prop

170 Altered mitochondrial morphology is evident consequential to Pim deletion together with decreased AT

171 about whether visual deficits are causal or consequential to reading disability encumbers accurate i

172 This energy shunt is consequential to the overall productivity of hypoxic wat

173 at this late stage of tolerance induction is consequential to their spontaneous activation in murine

174 m, the formation of generations, politically consequential transitions in adulthood, and the rising o

175 sis, sphingosine required Bax activation and consequential translocation to the mitochondria.

176 s attributable to the absence of m(1)A58 and consequential tRNA(i)(Met) instability.

177 ependent signalling pathways, as well as the consequential variations in cell growth, response to hyp

178 d to interact synergistically in various and consequential ways, having a substantial impact on the h

179 the redox-active hydrogen atom donor is also consequential, with 4-methoxythiophenol providing the be