1 ci and development of suitable markers takes
considerable effort.
2 basis of direct field observations, despite
considerable effort.
3 tant role in motivating actions that require
considerable effort.
4 iology by improving model quality and saving
considerable effort.
5 re unable to achieve advanced access despite
considerable efforts.
6 In spite of
considerable effort,
a full understanding of the pathway
7 Yet, despite
considerable effort,
a molecular-level understanding of
8 Despite
considerable efforts,
a comprehensive understanding of t
9 eir sustainability is essential and requires
considerable effort across a broad spectrum of fishery s
10 However, despite
considerable efforts,
an understanding of how molecular
11 lementation of these programmes will require
considerable effort and commitment.
12 l methods change clinical practice only with
considerable effort and difficulty.
13 Considerable effort and expense have been expended in at
14 g individual samples, these methods can save
considerable effort and genotyping costs when relatively
15 The
considerable effort and potential lack of reproducibilit
16 Despite
considerable effort and resources, no 'causative' geneti
17 These methods are limited by the
considerable effort and time required to obtain reliable
18 Despite
considerable effort,
antichlamydial vaccines have proven
19 Considerable efforts are being spent in the pharmaceutic
20 ries information in optoelectronic devices),
considerable efforts are directed at the development of
21 Thus,
considerable efforts are underway in the pharmaceutical
22 Considerable efforts are underway to fill this 'THz gap'
23 Thus, there is
considerable effort being made to improve the predictive
24 Despite
considerable effort by the pharmaceutical industry, PAR2
25 e WHO sodium target in New Zealand will take
considerable efforts by both food manufacturers and cons
26 Despite
considerable efforts by chemical biologists to synthesiz
27 Despite
considerable efforts by many groups over 4 decades, the
28 Considerable effort continues to be focused on improveme
29 Considerable effort continues to focus on developing a v
30 een one of the most elusive problems despite
considerable effort devoted to the study.
31 hepatic resection, the last decade has seen
considerable effort directed towards the following areas
32 However, the
considerable efforts embodied in these early studies unq
33 Despite
considerable effort examining the effect of IL-10 on spe
34 Considerable effort exists within drug discovery to deve
35 There has been
considerable effort focused on developing efficient prog
36 In recent years,
considerable effort has been aimed at developing B. subt
37 Considerable effort has been applied to separate their l
38 Therefore,
considerable effort has been dedicated to the developmen
39 Although
considerable effort has been devoted to annotating it, t
40 Considerable effort has been devoted to comparative stud
41 For this reason,
considerable effort has been devoted to determining the
42 use of this significant role in oncogenesis,
considerable effort has been devoted to elucidating the
43 Considerable effort has been devoted to elucidating the
44 electronics is reaching its ultimate limit,
considerable effort has been devoted to find new materia
45 Considerable effort has been devoted to gaining a mechan
46 Considerable effort has been devoted to identifying mole
47 Considerable effort has been devoted to identifying tran
48 Thus,
considerable effort has been devoted to mapping the func
49 Considerable effort has been devoted to modeling sample
50 , and increased incidence of bone fractures,
considerable effort has been devoted to the identificati
51 Although
considerable effort has been devoted to understanding ho
52 Considerable effort has been devoted to unraveling how t
53 Considerable effort has been directed at 'top-down' modi
54 Considerable effort has been directed to develop Mycobac
55 Considerable effort has been directed toward controlling
56 Although
considerable effort has been directed toward the mapping
57 ulated acutely by endocytic trafficking, and
considerable effort has been directed toward understandi
58 Although
considerable effort has been directed towards understand
59 Although
considerable effort has been exerted to define the event
60 Although
considerable effort has been expended developing drug ca
61 Considerable effort has been expended in striving for a
62 During the past 15 years
considerable effort has been expended in trying to estab
63 on is a worldwide public health problem, and
considerable effort has been expended on developing an e
64 iting factor in making large alignments, and
considerable effort has been expended over the years in
65 Considerable effort has been expended to determine wheth
66 Considerable effort has been expended to develop statist
67 Considerable effort has been expended to develop techniq
68 Considerable effort has been expended to increase sustai
69 increased use of gating in nuclear imaging,
considerable effort has been expended toward automating
70 In light of the importance of these cells,
considerable effort has been focused on understanding th
71 Considerable effort has been focused on understanding th
72 During recent years
considerable effort has been invested in creating physic
73 ogenesis of Alzheimer's disease, and, hence,
considerable effort has been invested in defining the me
74 al induction by Spemann and Mangold in 1924,
considerable effort has been invested in identifying the
75 A
considerable effort has been invested in the engineering
76 Considerable effort has been invested in the search of s
77 importance of algae for green biotechnology,
considerable effort has been invested in understanding t
78 Considerable effort has been invested in using IL-2 as a
79 Considerable effort has been invested into inoculum stra
80 Considerable effort has been made in elucidating the mec
81 Recently,
considerable effort has been made to analyze the binding
82 iated with the v-Src and v-Crk-oncoproteins,
considerable effort has been made to determine its funct
83 Considerable effort has been made to improve and harmoni
84 A
considerable effort has been placed in understanding the
85 Although
considerable effort has been placed on assuring the qual
86 s growing population of long-term survivors,
considerable effort has been put forth to identify treat
87 ans of modifying histone acetylation status,
considerable effort has been put into the development of
88 Considerable effort has been spent in developing transpl
89 of the inbred mouse in biomedical research,
considerable effort has been undertaken in recent years
90 Considerable effort has focused on identifying adjunctiv
91 During the past several decades,
considerable effort has focused on self-assembled system
92 Considerable effort has focused on the development of se
93 Considerable effort has focused on the identification of
94 Considerable effort has focused upon modulating the SMN2
95 Considerable effort has gone into designing vaccine regi
96 Therefore,
considerable effort has gone into determining the bioche
97 Over the past 10 years,
considerable effort has gone into improving diagnostic a
98 rmediates in many chemical reactions; hence,
considerable effort has gone into investigating their st
99 Considerable effort has gone into understanding the mech
100 Considerable effort has gone toward identification of di
101 of many of their synthetic counterparts, and
considerable effort has made since that time to develop
102 Considerable efforts have already been made to develop r
103 Considerable efforts have also been devoted towards the
104 Considerable efforts have been devoted in recent years t
105 underlie congenital muscular dystrophies and
considerable efforts have been devoted to explore this O
106 Considerable efforts have been devoted to this fruitful
107 Considerable efforts have been devoted toward uncovering
108 downstream of the T-cell receptor (TCR), and
considerable efforts have been directed toward discovery
109 Considerable efforts have been directed toward the disco
110 Considerable efforts have been directed toward understan
111 While
considerable efforts have been directed toward understan
112 Consequently,
considerable efforts have been made in recent years to f
113 As such,
considerable efforts have been made to develop small-mol
114 Considerable efforts have been made to develop technolog
115 Considerable efforts have been made to engineer AAV vari
116 Considerable efforts have been made to exploit cardiopro
117 Considerable efforts have been made to exploit this acti
118 Recently,
considerable efforts have been made to generate metallos
119 Recently,
considerable efforts have been made to produce them in a
120 Considerable efforts have been made to synthesize and ch
121 Although
considerable efforts have been made to understand why al
122 Over the last decades,
considerable efforts have been undertaken in the develop
123 Considerable efforts have gone into optimizing this ther
124 Neuroscientists have invested
considerable effort in attempting to elucidate the molec
125 Despite this, carers continue to invest
considerable effort in maintaining continuity in the car
126 However, despite
considerable effort in the 1980s, transmethylation has n
127 Circadian research has spent
considerable effort in the determining clock output path
128 Collaborative study groups have invested
considerable effort in the last decade in defining the r
129 Considerable efforts in electron-transfer theory have yi
130 nowires and nanotubes have been the focus of
considerable efforts in energy storage and solar energy
131 They also highlighted the need for
considerable efforts in the training of staff in the new
132 Despite
considerable efforts in understanding the binding intera
133 have been identified is growing rapidly and
considerable effort is being directed towards establishi
134 clinical drug candidates exist and therefore
considerable effort is being exerted to employ new tools
135 Considerable effort is being expended to define chemopre
136 evolutionary developmental comparisons, and
considerable effort is being invested in isolating devel
137 s frequently activated in cancer; therefore,
considerable effort is focused on identifying compounds
138 Considerable effort is focused on identifying transcript
139 For these reasons,
considerable effort is given to repairing even severely
140 ies is being developed for this purpose, and
considerable effort is invested into formally defining t
141 Considerable effort is now being focused on evaluating l
142 For that reason,
considerable effort is under way to devise methods of en
143 Despite
considerable effort,
little is known about the mode of a
144 s been in a quarter of a century and despite
considerable effort,
little progress has been observed i
145 However, despite
considerable efforts,
little is known about how enzymes
146 Although
considerable effort needs to be devoted to the continued
147 Despite
considerable efforts,
no essential cellular receptors fo
148 Despite
considerable efforts,
no reliable method exists to produ
149 This screen should save
considerable effort now wasted on directly cloning unsui
150 associated with Lyme borreliosis has focused
considerable effort on the development of a comprehensiv
151 There have been
considerable efforts on integration of plasmonic nanostr
152 Considerable effort over the last decade has been direct
153 porphyrins started flourishing recently with
considerable efforts over the past few years, as evidenc
154 Despite
considerable effort,
researchers understand little about
155 Despite
considerable effort,
rigorous interaction mapping in hum
156 Considerable effort should be expended to improve Form 2
157 Consequently, many labs spend
considerable effort testing methods to find one that wor
158 Despite the
considerable effort that has been invested in elucidatin
159 We will try to describe the
considerable effort that has gone into collecting eviden
160 Despite
considerable effort,
the complex interactions among diff
161 Despite
considerable effort,
the etiology of these devastating d
162 Despite
considerable effort,
the mechanism is unknown.
163 However, in spite of
considerable effort,
the mechanisms by which c-Myc inter
164 Despite
considerable effort,
the mechanisms underlying DR remain
165 Despite
considerable effort,
the slow-exchange limit could not b
166 Despite
considerable efforts,
the molecular and cellular events
167 for viral membrane fusion; however, despite
considerable efforts,
these critical host factors have d
168 Despite
considerable effort,
thus far there is no cure or treatm
169 There has been
considerable effort to determine structure-activity rela
170 Although there has been
considerable effort to develop a sensing platform for in
171 the copper oxide materials there has been a
considerable effort to find universal trends and correla
172 There is currently
considerable effort to incorporate both diagnostic and t
173 However, its user interface requires
considerable effort to learn, and sometimes requires pro
174 Despite
considerable effort to produce fuels from lignocellulosi
175 who initially refuse, whereas others expend
considerable effort to recruit reluctant respondents.
176 Currently, there is
considerable effort to replace existing precious-metal-c
177 In recent years there has been
considerable effort to understand the interaction of nan
178 Although there has been
considerable effort to understand the relationships betw
179 Considerable efforts to develop an effective vaccine for
180 iet, and subsequent weight loss, has spurred
considerable efforts to develop antagonists of MCHR1.
181 t-induced obesity of MCH KO mice has spurred
considerable efforts to develop small molecule MCHR1 ant
182 dence of lymphomas worldwide have stimulated
considerable efforts to identify factors that contribute
183 of neuronal Ca channel diversity has led to
considerable efforts to identify useful classification c
184 Despite
considerable efforts to improve early detection of ovari
185 Considerable efforts to make palladium and palladium all
186 Despite
considerable efforts to sequence hypermutated cancers su
187 chnologically useful behaviours have spurred
considerable efforts to synthesize a broad array of nega
188 There have been
considerable efforts to synthesize new zeolites with spe
189 In recent years, there have been
considerable efforts to translate this solution-based re
190 eptor, mGlu5; therefore, our lab has focused
considerable effort toward developing mGlu1 positive all
191 It took
considerable effort until scientists accepted that lipid
192 Despite intense interest and
considerable effort via high-throughput screening, there
193 However, a
considerable effort will be required to optimize this ap
194 Despite
considerable efforts within the microarray community for