ライフサイエンスコーパス: constitutive

1 he immune receptor gene SUPRESSOR OF npr1-1, CONSTITUTIVE 1 (SNC1) and modulate its expression and co

2 a shoot- or root-specific promoter, and the constitutive 35S promoter in Arabidopsis.

3 logical stabilization of HIFs retained their constitutive ability for early metastatic seeding in an

4 Constitutive ablation of all six members of this miRNA f

5 hen developmental accumulation of WhiB joins constitutive accumulation of WhiA, suggesting that an im

6 ssion of ML1 in mouse parietal cells induced constitutive acid secretion.

7 nables assessment of chromatin contacts both constitutive across and specific to tissue(s) and/or cel

8 O-GlcNAcylation has been linked to NF-kappaB constitutive activation and cancer development.

9 Loss of ClpC repression in MD mutants causes constitutive activation and severe cellular toxicity.

10 n of SYK activity eliminated features of the constitutive activation in these cells and partly restor

11 er, our studies indicate that stress-induced constitutive activation is a novel mechanism of kappaOR

12 endocrine therapy via mutation of ERs whose constitutive activation is associated with shorter patie

13 nt, the data suggest that controlled but not constitutive activation is required for gonococcal infec

14 High SYK expression by itself drives the constitutive activation observed in these B cells, which

15 suggested miR-17 approximately 92's role in constitutive activation of BCR signaling and sensitivity

16 Constitutive activation of beta-catenin in hematopoietic

17 In addition, the constitutive activation of beta-catenin significantly in

18 e morphology defects, growth inhibition, and constitutive activation of BR signaling.

19 Constitutive activation of CD40 in DCs results in inflam

20 EGF/FGF2-independent proliferation exhibited constitutive activation of EGFR, AKT, and STAT3 and sens

21 lts suggest that SAM domain deletion induced constitutive activation of EphA2 kinase activity.

22 Constitutive activation of Galphaq signaling by mutation

23 predispose to paraganglioma tumors that show constitutive activation of hypoxia responses.

24 Notably, constitutive activation of IkappaBalpha/NF-kappaB(p65) i

25 wn genomic alterations in glioma that induce constitutive activation of MAPK are transcriptionally li

26 These data indicate constitutive activation of mitophagy results in reductio

27 Constitutive activation of mTORC1 by depletion of tubero

28 st, glucose did not suppress mTORC1, and the constitutive activation of mTORC1 failed to suppress pla

29 ed mTORC1 signaling in vitro and in vivo The constitutive activation of mTORC1 reduced hepatic lipoge

30 e/paracrine TLR5 signaling loop resulting in constitutive activation of NF-kappaB both in vitro and i

31 and Hnf1b Consistent with this, we find that constitutive activation of Notch in mesenchymal nephron

32 Constitutive activation of Notch signaling fully blocked

33 Accordingly, constitutive activation of Notch1 prevents SC depletion

34 Somatic mutations that lead to constitutive activation of NRAS and KRAS proto-oncogenes

35 ubicin or nutlin-3 results in continuing and constitutive activation of p53, inhibition of XIAP and s

36 Constitutive activation of PDGFRalpha leads to expansion

37 We further show that constitutive activation of PKB in vivo results in a loss

38 lterations in MIBC that convergently lead to constitutive activation of PPARgamma/RXRalpha and result

39 vasion phenotypes is mediated in part by the constitutive activation of pro-inflammatory nuclear fact

40 Constitutive activation of RhoA led to increased express

41 rfism, compromised pollen tube guidance, and constitutive activation of salicyclic acid-mediated defe

42 results indicate that oncogenic Kras induces constitutive activation of SOX9 in HPNE and HPDE cells,

43 g-term plasticity, little is known about how constitutive activation of specific kinase isoforms sust

44 es dysregulation of apoptosis, mainly due to constitutive activation of survival pathways including J

45 of chronic energy deprivation, resulting in constitutive activation of the energy-stress sensor AMPK

46 followed by a persistent, ligand-independent constitutive activation of the kappaOR itself.

47 ve fitness normalize GSK3beta activity after constitutive activation of the MAPK pathway, commonly th

48 es, elevated baseline expression relied upon constitutive activation of the MAPK pathway.

49 nal proline-rich motif of FGFR2 inducing the constitutive activation of the receptor, thereby prompti

50 Accordingly, IL6 mediated constitutive activation of the STAT3 pathway, an essenti

51 IL6-mediated inflammation programs constitutive activation of the TAK1-NFkappaB signaling c

52 In fact, in CD44+/CD24- cells, constitutive activation of the TGF-beta axis was both ne

53 Constitutive activation of the Wnt pathway resulting fro

54 Constitutive activation of the Wnt pathway, one of the e

55 These mutations confer cGAMP-independent constitutive activation of type I interferon signaling t

56 Constitutive activation of Wnt-beta-catenin signaling fu

57 This constitutive activation was abrogated by ex vivo treatme

58 n in synapses of KI mice, demonstrating that constitutive active FAK signaling downstream of the Pro3

59 T lymphocytes from patients carrying constitutive active mutations in TMEM173 encoding STING

60 The nuclear protein constitutive active/androstane receptor (CAR or NR1I3) r

61 ed outward receptor currents by reducing the constitutive activities of odorant receptors, inhibiting

62 e specific sets of PKMs in each neuron whose constitutive activities sustain long-term synaptic plast

63 re, the R156 receptor variant showed greater constitutive activity and a higher affinity for ligand.

64 ctive conformation of MEK1, resulting in its constitutive activity and making it more prone to Raf-me

65 CAR inactivates its constitutive activity by phosphorylation at threonine 38

66 that enables inter-domain communication and constitutive activity from the N-terminal coactivator-bi

67 Furthermore, this abrogated constitutive activity of 5-HT2B/C receptors and abolishe

68 ucidated the effects of ABA plus knockout or constitutive activity of 79 nodes on both the outcome of

69 ion of F508-CFTR are partially suppressed by constitutive activity of Hsc70 and Hsp90 chaperone/co-ch

70 We also provide evidence that constitutive activity of kappaORs governs the prolonged

71 3-associated phenotypes, indicating that the constitutive activity of MPK3 can bypass SA and ethylene

72 recent studies have suggested that low-level constitutive activity of TRPV3 induces EGFR-dependent si

73 nism, allosteric modulation, signaling bias, constitutive activity, and inverse agonism.

74 Several of these mutations result in MEK1 constitutive activity, but how they affect MEK1 regulati

75 Constitutive Akt signalling increases expression of EC m

76 n erroneous assumption that they are largely constitutive and housekeeping enzymes.

77 We found evidence of constitutive and hypoxia-induced expression of CL-11 in

78 By contrast, MS32 is constitutive and independently regulated and is required

79 We found abundant genetic variation in both constitutive and induced traits related to plant-water r

80 Rs-from acting synergistically with existing constitutive and inducible regulators, to reprogramming

81 constitutes a relevant model to investigate constitutive and injury-induced neurogenesis in adult ve

82 Both constitutive and neuronal-specific promoters were able t

83 at mediate DAT endocytic recycling following constitutive and regulated internalization.

84 We then tested the constitutive and responsive behaviors of two strong quan

85 of the introns significantly differ between constitutive and retained introns.

86 posure also increased mRNAs encoding hepatic constitutive androstane receptor (3-fold) and its target

87 The constitutive androstane receptor (CAR) plays an importan

88 This framework allows one to easily change constitutive assumptions within these models.

89 Constitutive B-cell receptor signaling leads to overexpr

90 We hypothesized that constitutive BCR activation precluded functional B-cell

91 hromatin immunoprecipitation analyses reveal constitutive binding of CREB to target gene promoters in

92 ndicated that NtPDR1 is involved not only in constitutive but also in induced plant defenses.

93 he expression of high levels of Eomes is not constitutive but rather requires a continuum of cell-int

94 A on host fitness reduced transcription from constitutive, but not activator-dependent, promoters.

95 t, substrate gene expression was restored by constitutive, but not native, expression of the whiB6 ge

96 s produce uniporter subcomplexes that induce constitutive Ca(2+) leakage into mitochondria, a conditi

97 al ribonucleoprotein complex, along with its constitutive capsid protein, plays essential roles at vi

98 Although all the mutations result in constitutive caspase-1 activation, their phenotypic pres

99 SUG1 and ubiquitinated proteins, triggering constitutive caspase-8-mediated cell death dependent on

100 oreover, pups exposed to WIN in utero lacked constitutive CB1R-mediated suppression of inhibition fro

101 r their ability to concordantly decrease the constitutive CCL17 secretion of a human Hodgkin lymphoma

102 otein 1 (LMP)/CD40 fusion protein conferring constitutive CD40 signaling under control of the DC-spec

103 However, the constitutive cell cycle activity of these niches remains

104 n and cellular localization of the different constitutive cell wall components (especially of the out

105 Constitutive cell-autonomous immunity in metazoans preda

106 The signals controlling deployment of constitutive cell-autonomous responses during infection

107 overns centromere function by recruiting the constitutive centromere associated network (CCAN) comple

108 th the negatively-charged Glu did not induce constitutive channel opening.

109 also known as CXCR7, binds and degrades the constitutive chemokine CXCL12, which also binds the cano

110 a genetic factor known to be associated with constitutive CK levels is also associated with CK variab

111 Analysis of constitutive CME is difficult because the initiation of

112 show that TMM and ER or ER-LIKE1 (ERL1) form constitutive complexes, which recognize EPF1 and EPF2, b

113 e pull-down analysis revealed that PARN is a constitutive component of the Bystin-associated pre-40S

114 revealed that BCL9 and B9L, like PYGO2, are constitutive components of the Wnt enhanceosome.

115 muscle gene, CKM Glu83Gly (rs11559024) with constitutive creatine phosphokinase (CK) levels, CK vari

116 preexisting topological framework created by constitutive CTCF-mediated interactions.

117 tabacum has been shown to be involved in the constitutive defense against pathogens through the secre

118 rmine relative MPB attack susceptibility and constitutive defenses.

119 r cells and ICs, PD-L1 patterns (adaptive vs constitutive), degree of IC infiltration, quantified den

120 Moreover, constitutive deletion of the Abetao-binding cellular pri

121 Constitutive depletion of p21-activated kinase 4 (PAK4)

122 al rock-inhabiting ascomycete synthesizing a constitutive DHN-melanin, Cryomyces antarcticus (CA); me

123 ilar reorganization of actin is induced by a constitutive dimer of MYO6+, indicating that multimeriza

124 (FRET) approach to show that Ecadherin forms constitutive dimers and that these dimers exist independ

125 This neuronal pathology is prevented by constitutive disruption of Nat8l, which encodes the neur

126 NtPDR1 transports compounds involved in both constitutive (diterpenes) and induced (sesquiterpenes) p

127 tidine deaminase-deficient cells to tolerate constitutive DNA damage and replication stress.

128 by several non-exclusive markers, including constitutive DNA damage response (DDR) signaling, senesc

129 ated cholesterol clearance in macrophages in constitutive, dose-dependent, and reversible fashion but

130 Specifically, constitutive downregulation of molecular chaperones was

131 mvented developmental compensations found in constitutive Drd2(-/-) mice and allowed us to directly e

132 This analysis confirmed the constitutive effect of the chromosome 1B QTL and explain

133 VE-cadherin endocytosis does not require the constitutive endocytic motif.

134 We show that GPR15 undergoes a constitutive endocytosis in the absence of ligand.

135 plasma membrane of mammalian cells undergoes constitutive endocytosis, endocytic sorting, and recycli

136 ows that oncogenic RAS specifically triggers constitutive endocytosis-dependent movement of effector

137 es for TLR4, TLR5, IL-1R and CD11c+ cells in constitutive epithelial barrier function against P. aeru

138 emonstrated that the Y537S mutation promotes constitutive ER activity globally, resulting in estrogen

139 Conversely, EVI1 silencing had no effect on constitutive ERK activity in HER2(+) breast carcinoma ce

140 B adducts, illustrating that a mitochondrial constitutive excretion mechanism ensures rapid disposal

141 Constitutive expression of Cyp1a1 throughout the body or

142 eticulocytes remained unexplained, given the constitutive expression of DARC during reticulocyte matu

143 enhanced accumulation of abscisic acid, the constitutive expression of genes encoding antibiotic pep

144 We find that constitutive expression of GFP-AtSAUR19 bypasses the nor

145 Constitutive expression of GLI3 repressor in Ptch1-defic

146 in donors on suppressive ART consistent with constitutive expression of HIV RNA in infected cell clon

147 Constitutive expression of HopAI with the RP27 or TrpC p

148 er individuals into two extremes: those with constitutive expression of IL-1beta, nucleotide metaboli

149 on and arterial stiffness; and those without constitutive expression of IL-1beta, who lack these char

150 -AMP synthase-mediated signaling and reduces constitutive expression of interferon in macrophages fro

151 opment in rice vascular sheath cells through constitutive expression of maize GOLDEN2-LIKE genes.

152 and complete rescue of invasiveness in vitro Constitutive expression of miR-92a-3p or inhibition of m

153 mposition of defense-induced lignin, whereas constitutive expression of MYB15 increases lignin conten

154 Moreover, constitutive expression of SAP2 or SAP5 in two distinct

155 hat results in Ser200 Leu substitution and a constitutive expression of the Pho regulon.

156 provides an additional benchmark for strong constitutive expression of transgenes in Chlamydomonas,

157 xication, which is attributed in part to the constitutive expression of two importers: the proton-dep

158 get gene, whiB, and that deletion of bldO or constitutive expression of whiB is sufficient to induce

159 n contrast to alphaVbeta6, alphaVbeta8 has a constitutive extended-closed conformation, and binding t

160 rship when enemy challenged, and resulted in constitutive fitness costs in the absence of parasitism.

161 nclear since the CB2R gene knockout mice are constitutive gene knockout.

162 urons is also negatively modulated by tonic, constitutive GPCR activity as TRPM3 responses can be pot

163 However, the mechanism that maintains constitutive GRK2 association with DOR is unknown.

164 horylation target, in clock neurons and that constitutive HDAC4 localization in the nucleus shortens

165 pontaneous liver fibrogenesis in EC-specific constitutive hemi-deficient (Erg (cEC-Het) ) and inducib

166 s of repetitive DNA organized in the form of constitutive heterochromatin and associated with repress

167 es to the stable association of SUV39H1 with constitutive heterochromatin in human cells.

168 Constitutive heterochromatin is an important component o

169 Constitutive heterochromatin is commonly associated with

170 36); a site associated with the formation of constitutive heterochromatin, lysine 9 (H3K9); and a sit

171 Yet, it is frequently constrained by constitutive heterochromatin, usually characterized by h

172 repeat arrays, may lead to the formation of constitutive heterochromatin.

173 In the cell, Timeless forms a constitutive heterodimeric complex with Tipin.

174 a and IL-36beta mRNA in infected skin, while constitutive IL-36gamma levels remained largely unchange

175 structure of the microbiota where flies with constitutive immunity defined the gut microbiota of thei

176 eptor expression below that required for the constitutive increase.

177 ty and stress hypersensitivity are driven by constitutive increases in CRF1 signaling that dysregulat

178 th fully intact transcriptional activity and constitutive induction of downstream target genes, even

179 Using CDK inhibitors to reverse the constitutive inhibitory phosphorylation of T387 of U-STA

180 MC4R undergoes constitutive internalization and recycling to the plasma

181 Vascular endothelial (VE)-cadherin undergoes constitutive internalization driven by a unique endocyti

182 The plant lignan justicidin B blocked the constitutive internalization of LGR5.

183 NT/beta-catenin signaling through its unique constitutive internalization property that clears negati

184 revealed that GPRC6A predominantly undergoes constitutive internalization, whereas the agonist-induce

185 By comparing retained and constitutive introns, we identified sequence features po

186 h-point region differed between retained and constitutive introns.

187 Constitutive JA signaling in a jaz quintuple mutant (jaz

188 everal oncogenic driver mutations leading to constitutive JAK-STAT activation, the cellular and molec

189 Although the molecular basis of this constitutive JAK/STAT signaling in cHL has not been comp

190 Constitutive JAK/STAT signaling is crucial for survival

191 Conversely, constitutive KIBRA knockout mice displayed reduced phosp

192 Although Cdkl5 constitutive knock-out mice have recapitulated key aspec

193 Recently, our laboratory has shown that a constitutive knockout of p11 (p11-KO) in mice results in

194 These PI3K lipid kinases phosphorylate the constitutive lipid phosphatidylinositol-4,5-bisphosphate

195 he mechanisms of resistance used to tolerate constitutive, long-term exposure to DNA methylation.

196 regulatory elements are often nested within constitutive loops anchored by CTCF.

197 ged as long as the total time delay over the constitutive loops of the network is conserved.

198 e found that lysosomal dysfunction induces a constitutive lysosomal association and consequent activa

199 -directed action representation system, in a constitutive manner that is independent from perceptual

200 tions, and hence developed in the absence of constitutive MAPK pathway activation.

201 Our data provide evidence that constitutive MDM2-ALT1 expression is itself an oncogenic

202 An empirical constitutive model is calibrated based on the experiment

203 Hence, a full microstructural constitutive model is required for better understanding

204 f controlled single particle impact data and constitutive models, provides an innovative approach for

205 viously been reported to oscillate, than the constitutive MoMuLV 5' LTR (MMLV) promoter (0/25).

206 which act to break down macromolecules into constitutive monomers that can be transported into cells

207 Constitutive mRNAs (MDN1 and DOA1) and highly-regulated

208 Finally, we found that constitutive mTOR activation lowered a behavioral measur

209 osis complex 2 (TSC2(-/-) cells), which show constitutive MTORC1 activation.

210 SZT2 deficiency resulted in constitutive mTORC1 signalling in cells under nutrient-d

211 th the development of various cancers, where constitutive NF-kappaB activation is often found to prom

212 We found that constitutive NIK expression decreased expression of nume

213 We previously showed that constitutive NIK expression in all T cells causes fatal

214 Here, we show that constitutive NIK expression that is restricted to Tregs

215 7a and Tnf knockout backgrounds allowing for constitutive Nlrp3 activation in myeloid derived cells i

216 f liver inflammation and fibrosis induced by constitutive NLRP3 inflammasome activation in myeloid-de

217 pendent induction mechanism and suggest that constitutive NOTCH3 signaling can drive an oncogenic pro

218 In this study we explored the role of constitutive Nox4 activity in regulating mitochondrial f

219 rotic lung allografts (BOS MCs) demonstrated constitutive nuclear beta-catenin expression that was de

220 e interdomain interactions caused either AHR constitutive nuclear localization or failure to transloc

221 ted hematopoiesis in mice heterozygous for a constitutive null Dnmt3a mutation.

222 ng model proposes that negative emotions are constitutive of aesthetic experiences.

223 to the negatively-charged Glu did not induce constitutive opening of Slo2.1 or Slo2.2, suggesting tha

224 We report data from mice with constitutive or conditional deletion of HDAC11 within Fo

225 alin ABDs regulate actin polymerization in a constitutive or regulated manner has not been fully expl

226 different engineered transposon variants for constitutive or tissue-specific cancer gene discovery sc

227 hers lost rhythmicity with age, resulting in constitutive over- or under-expression.

228 We further show that constitutive overexpression of HuR is able to maintain R

229 Constitutive overexpression of miR858 interfered with H.

230 rosis, ATII-specific deficiency of VEGF-A or constitutive overexpression of VEGF-A165b inhibited the

231 of rare Mendelian disorders associated with constitutive overproduction of type I IFN has provided u

232 1 binding, whereas the MLL moiety provided a constitutive PAF1 tether allowing MLL fusions to circumv

233 ng of F-Z data to extract their viscoelastic constitutive parameters.

234 For each cell line, we monitored constitutive PARP activation, spontaneous DNA damage by

235 thin the hepatic vascular niche represents a constitutive pathway indispensable for iron homeostasis

236 Importantly, Mot2 is not involved in the constitutive pathway of Mei2 turnover, but rather plays

237 Constitutive PB mutagenesis in Arf(-/-) mice provided a

238 Constitutive Pck activation promoted dephosphorylation a

239 Both adaptive (IC-associated) and constitutive PD-L1 expression patterns were observed.

240 Mice with constitutive PDGFRbeta signaling caused by a kinase doma

241 or endocrine site of production/secretion of constitutive pepcan-12, as shown by its marked loss afte

242 compounds (about 5 eV), which depends on the constitutive phase (2.8 eV in cerussite and 2.1 eV in hy

243 vestigate the evolution of elastic strain of constitutive phases and their interactions, such as load

244 elisib potently killed 3 of 4 TCL lines with constitutive phospho-AKT (pAKT) vs 0 of 7 lines lacking

245 crotubule interface, as mutations that mimic constitutive phosphorylation destabilized K fibers in vi

246 In double-knockout mice, constitutive phosphorylation of EIF2A and over-expressio

247 own-regulation of VIL1 and GSN, resulting in constitutive phosphorylation of EIF2A and overexpression

248 ermore, a Ser96Asp HRC variant, which mimics constitutive phosphorylation of Ser96, diminished delaye

249 this high expression is sufficient to drive constitutive phosphorylation of SYK and its immediate ta

250 Constitutive photomorphogenesis 9 (COP9) signalosome 5 (

251 he BIC genes, by suppressing the activity of CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1), resulting in act

252 hat the hfr1 mutant partially suppresses the constitutive photomorphogenic phenotypes of cop1-6 pif1

253 and biochemical evidence that FKF1 inhibits CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1)-dependent CO degra

254 xpression of pCF10-encoded prg/pcf genes, or constitutive PrgU overproduction, block production of th

255 ggesting that extrinsic sialylation is not a constitutive process.

256 rmation of epicotyls was unsuccessful when a constitutive promoter (2x CaMV 35S) was used in the plas

257 tags, all of which were driven from a strong constitutive promoter ermEp*.

258 Overexpression of AtDRO1 under a constitutive promoter resulted in steeper lateral root a

259 xpressed Atf1 phosphorylation mutants from a constitutive promoter to uncouple Atf1 activity from end

260 of the phage promoter has provided a set of constitutive promoters that span over four logs of stren

261 ivergence in function between the iP and the constitutive proteasome (cP) has been unclear.

262 ges within the ALY epitope compared with the constitutive proteasome.

263 Hcy is sensed by a constitutive protein complex composed of leucyl-tRNA-syn

264 However, AnkG did alter ENaC insertion from constitutive recycling pathways.

265 c development genes, housekeeping genes, and constitutive regulatory elements, which are known to sho

266 fragments (tRFs) are an established class of constitutive regulatory molecules that arise from precur

267 As a result, the constitutive relations of chiral active media display a

268 iscoelastic properties with arbitrary linear constitutive relations.

269 We detected high-level constitutive release of Hsp70 and Hsp90 associated with

270 operties of primary trophoblasts through the constitutive release of type III IFNs (IFNlambda1 and IF

271 tivity of paracrine effectors, including the constitutive release of type III interferons (IFNs).

272 However, constitutive repression of CCN3 by the Polycomb group pr

273 wth phenotype in the presence of S(0) due to constitutive repression of S(0) -responsive genes.

274 Eight mutations yielding constitutive Rgg2 activity, designated Rgg2Sp*, were ide

275 engineered an armored CAR T cell capable of constitutive secretion of IL-12, and delineate the mecha

276 the immunosuppressive ligand PD-L1, a higher constitutive secretion of IL-6 and increased basal alpha

277 ly due to reductions in VWF synthesis and/or constitutive secretion.

278 ssion and compared the results with those of constitutive SERT knockout.

279 We show that the S672R mutation results in a constitutive shift of the dynamic auto-inhibitory equili

280 Constitutive Shisa2 expression causes randomized turning

281 Here, we show that constitutive signaling driven by mutated FLT3 and JAK2 c

282 that B and T lymphocytes exhibit low-level, constitutive signaling in the basal state (tonic signali

283 ion needs to be carefully regulated, because constitutive signaling or detection of endogenous RNA th

284 tures suggest a mechanism for the control of constitutive signaling, and their unusually high resolut

285 own to significantly increase the receptors' constitutive signaling, we examined two different bilate

286 y reduced by either antioxidant treatment or constitutive SKN-1/Nrf2 activation.

287 esterol within the bilayer is sufficient for constitutive Smoothened activation.

288 Constitutive Ssb1/Ssb2 double knockout (DKO) caused earl

289 senchymal cells on the other hand, exhibited constitutive TGF-beta signaling and were less tumorigeni

290 Here, we report that JAK1 is a constitutive TGFbetaRI binding protein and is absolutely

291 nition of EPF1 and EPF2, indicating that the constitutive TMM-ERf complexes function as the receptors

292 ent does not contribute significantly to the constitutive transcriptional dynamics of primary B-cells

293 on the F-box protein ZEITLUPE, and implicate CONSTITUTIVE TRIPLE RESPONSE1 (CTR1), a negative regulat

294 Conversely, the constitutive triple-response mutant ctr1-1, was less att

295 In the current study, a constitutive TSC1 transgenic (Tsc1 (tg) ) mouse model wa

296 Here, we report that constitutive Twf2a-deficient mice (Twf2a(-/-)) display m

297 pression levels of OCP1, which appears to be constitutive; under low irradiance, OCP2 expression was

298 its adaptive significance appear to involve constitutive up-regulation of sulfate/selenate uptake an

299 interferon signaling by RNA-Seq analysis and constitutive upregulation of phosphorylated STAT1 and ST

300 This mechanism allows constitutive VE-cadherin endocytosis and recycling to co