ライフサイエンスコーパス: constitutive androstane receptor

1 iferator-activated receptor gamma, and mouse constitutive androstane receptor).

2 xenobiotic receptors pregnane X receptor and constitutive androstane receptor.

3 posure also increased mRNAs encoding hepatic constitutive androstane receptor (3-fold) and its target

4 chanisms, such as an increased activation of constitutive androstane receptor and a decreased activat

5 hese regulatory activities was downstream of constitutive androstane receptor and beta-catenin signal

6 nd the expression of the target genes of the constitutive androstane receptor and the integrin-linked

7 The ability of PXR and constitutive androstane receptor and their ligands to tr

8 mediated induction through the activation of constitutive androstane receptor and/or pregnane X recep

9 receptors PXR (pregnane X receptor) and CAR (constitutive androstane receptor) and the vitamin D(3)-a

10 ctivated receptors, LXRs, thyroid receptors, constitutive androstane receptor, and pregnane X recepto

11 e sensitizing effect of pregnane X receptor, constitutive androstane receptor, and retinoid X recepto

12 have identified the xenobiotic receptor CAR (constitutive androstane receptor) as a key regulator of

13 CAR-beta (constitutive androstane receptor-beta), therefore, defin

14 Constitutive androstane receptor CAR (NR1I3) has been id

15 We have shown previously that constitutive androstane receptor (CAR) (a xenobiotic-sen

16 Hepatic expression of the constitutive androstane receptor (CAR) and its target ge

17 the role of the nuclear xenobiotic receptors constitutive androstane receptor (CAR) and pregnane and

18 tudies have shown that the nuclear receptors constitutive androstane receptor (CAR) and pregnane X re

19 Constitutive androstane receptor (CAR) and pregnane X re

20 o be regulated through the nuclear receptors constitutive androstane receptor (CAR) and pregnane X re

21 nvolved in phenobarbital (PB) induction, the constitutive androstane receptor (CAR) and pregnane X re

22 ptor (NR) binding sites for a heterodimer of constitutive androstane receptor (CAR) and retinoid X re

23 ound that TCS activates the nuclear receptor constitutive androstane receptor (CAR) and, contrary to

24 The pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are implicated in

25 lear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are xenosensors p

26 enes, while similar studies have established constitutive androstane receptor (CAR) as a CYP2B regula

27 Here we identified constitutive androstane receptor (CAR) as a positive reg

28 lear receptors small heterodimer partner and constitutive androstane receptor (CAR) as well as genes

29 is of the CYP2C19 promoter revealed a single constitutive androstane receptor (CAR) binding site (CAR

30 The constitutive androstane receptor (CAR) enhances transcri

31 Recently, the nuclear receptor constitutive androstane receptor (CAR) has been identifi

32 d others induce the nuclear translocation of constitutive androstane receptor (CAR) in mouse liver ce

33 The role of the constitutive androstane receptor (CAR) in xenobiotic met

34 Constitutive androstane receptor (CAR) induces xenobioti

35 Constitutive androstane receptor (CAR) is a central regu

36 Constitutive androstane receptor (CAR) is a key regulato

37 Constitutive androstane receptor (CAR) is a nuclear rece

38 Nuclear translocation of constitutive androstane receptor (CAR) is a primary mech

39 ire ligand for transcriptional activity, the constitutive androstane receptor (CAR) is active in the

40 The orphan nuclear constitutive androstane receptor (CAR) is proposed to pl

41 m that has been attributed to differences in constitutive androstane receptor (CAR) levels.

42 hyperplastic influences in liver mediated by constitutive androstane receptor (CAR) ligands phenobarb

43 Because the nuclear hormone receptor constitutive androstane receptor (CAR) mediates hepatic

44 The constitutive androstane receptor (CAR) mediates the hepa

45 The constitutive androstane receptor (CAR) modulates xeno- a

46 The nuclear pregnane X receptor (PXR) and constitutive androstane receptor (CAR) play central role

47 The constitutive androstane receptor (CAR) plays an importan

48 Constitutive androstane receptor (CAR) regulates hepatic

49 -/-) mice had higher messenger RNA levels of constitutive androstane receptor (Car) than wild-type BD

50 Constitutive androstane receptor (CAR) was found to be o

51 The constitutive androstane receptor (CAR) was initially cha

52 lear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) were originally i

53 Nuclear and cytosolic localization of the constitutive androstane receptor (CAR), a transcription

54 evels and jet-lag-induced HCC, while loss of constitutive androstane receptor (CAR), a well-known liv

55 The constitutive androstane receptor (CAR), a xenosensor, is

56 The xenobiotic receptors, constitutive androstane receptor (CAR), and pregnane X r

57 xenobiotic agonists of the nuclear receptors constitutive androstane receptor (CAR), aryl hydrocarbon

58 ctors such as the pregnane X receptor (PXR), constitutive androstane receptor (CAR), glucocorticoid r

59 s, such as the pregnane X receptor (PXR) and constitutive androstane receptor (CAR), may underlie the

60 aloropyridyloxy)] benzene) an agonist of the constitutive androstane receptor (CAR), produces rapid h

61 se to xenobiotics, cross-talk between ER and constitutive androstane receptor (CAR), steroid and xeno

62 ceptor (PXR), along with its sister receptor constitutive androstane receptor (CAR), was initially ch

63 ring conditional expression of the activated constitutive androstane receptor (CAR), we demonstrate t

64 ] benzene), a ligand of the nuclear receptor constitutive androstane receptor (CAR).

65 2B expression in liver via activation of the constitutive androstane receptor (CAR).

66 es by PB is mediated by the nuclear receptor constitutive androstane receptor (CAR).

67 CPOBOP is a ligand for the nuclear receptor, constitutive androstane receptor (CAR).

68 The human constitutive androstane receptor (CAR, CAR1) regulates t

69 We recently identified the constitutive androstane receptor (CAR, NR1I3) as a key r

70 Expression of the constitutive androstane receptor (CAR, NR1I3) is enriche

71 The constitutive androstane receptor (CAR, NR1i3), a known x

72 he CYP2B6 gene is primarily regulated by the constitutive androstane receptor (CAR, NR1I3), we hypoth

73 may in part occur through the action of the constitutive androstane receptor (CAR, NR1I3).

74 by the pregnane X receptor (PXR, NR1I2) and constitutive androstane receptor (CAR, NR1I3).

75 The X-ray crystal structure of the human constitutive androstane receptor (CAR, NR1I3)/retinoid X

76 ytochromes P450 (CYPs) 2B and 3A through the constitutive androstane receptor (CAR; NR1I3) and pregna

77 The constitutive androstane receptor (CAR; NR1I3) and to a l

78 ly, the pregnane X receptor (PXR; NR1I2) and constitutive androstane receptor (CAR; NR1I3) have been

79 The human constitutive androstane receptor (CAR; NR1I3) is express

80 ceptors pregnane X receptor (PXR; NR1I2) and constitutive androstane receptor (CAR; NR1I3) regulate C

81 As a promiscuous xenobiotic sensor, the constitutive androstane receptor (CAR; NR1I3) regulates

82 ligand for the related nuclear receptor, the constitutive androstane receptor, does not overcome the

83 nown about the chemical specificity of human constitutive androstane receptor (hCAR) and its regulati

84 rsenoid X receptor, pregnane X receptor, and constitutive androstane receptor in bile acid homeostasi

85 ceptor constitutive active receptor (CAR, or constitutive androstane receptor) in mouse liver.

86 XENKO) lacking the xenobiotic receptors CAR (constitutive androstane receptor) (NR1I3) and PXR (pregn

87 iver and small intestine independent of PXR, constitutive androstane receptor, or hepatic nuclear fac

88 educed by activation of pregnane X receptor, constitutive androstane receptor, or nuclear factor-kapp

89 erase 1A2; NAD(P)H dehydrogenase, quinone 1; constitutive androstane receptor; or nuclear factor eryt

90 Activation of the nuclear receptors constitutive androstane receptor, pregnane X receptor, a

91 Nuclear receptors, including constitutive androstane receptor, pregnane X receptor, a

92 ation of PXR, but not of the closely related constitutive androstane receptor, profoundly reduced cir

93 odons produce amino-terminal-truncated human constitutive androstane receptor protein isoforms (Delta