ライフサイエンスコーパス: constitutive expression

1 Constitutive expression and activation of YAP inversely

2 h B. henselae strains demonstrated that both constitutive expression and deletion of hbpC affect the

3 p of the SPRR1B 5'-flanking region regulated constitutive expression and increased promoter activity

4 and degradation are derived for the case of constitutive expression and subsequently extended to pro

5 k of response, increased activation, altered constitutive expression, and dysregulated response kinet

6 flH and NflD in all known methanogens, their constitutive expression, and their high sequence similar

7 BbdA's high affinity for BAM and its constitutive expression are of interest for using strain

8 pha is functionally important, because their constitutive expression completely reverses differentiat

9 a conditional mouse model, we show that Agr2 constitutive expression drives precocious lobuloalveolar

10 e effect was that chromosome position alters constitutive expression, due to changes in gene copy num

11 This family exhibits constitutive expression during larval development and is

12 neurin/NFAT regulation did not contribute to constitutive expression elsewhere or to inflammatory COX

13 og causes early embryonic lethality, whereas constitutive expression enables autonomous self-renewal

14 In development, the absence of p53 impacted constitutive expression for a surprisingly broad scope o

15 ion of cancer, has abnormal NF-kappaB-driven constitutive expression in AML.

16 ional in chicken cells and that knockdown of constitutive expression in chicken fibroblasts results i

17 6b) belong to a subset of keratin genes with constitutive expression in epithelial appendages, and in

18 on expression: CAAT box mutations modulated constitutive expression in nonlymphoid tissues, whereas

19 nic MSCs and may be a factor involved in its constitutive expression in vivo.

20 nts rpoE induction during stress, but leaves constitutive expression intact, and allows cell viabilit

21 y all loci, episodic bursting--as opposed to constitutive expression--is the predominant mode of expr

22 Specifically, gene clustering did not alter constitutive expression levels or stochastic fluctuation

23 op antiinflammatory therapies that spare the constitutive expression necessary for normal homeostatic

24 Constitutive expression of 10A06 in Arabidopsis affected

25 in the cochlear sensory epithelium revealed constitutive expression of 176 miRNAs, many of which hav

26 under various growth conditions demonstrated constitutive expression of 7 genes, variable expression

27 Transgenic mice (Kit(copGFP/+)) with constitutive expression of a bright green fluorescent pr

28 We show here that constitutive expression of a C-terminal mutant OAZ (OAZD

29 ation of the myristoylated glycine triggered constitutive expression of a calcineurin-dependent repor

30 ocytes, since knockdown of SIRT1 through the constitutive expression of a corresponding RNA interfere

31 Constitutive expression of a GTPase defective Dominant N

32 We describe pRedScript, which introduces the constitutive expression of a very bright red fluorescent

33 47R) expression in mouse mammary glands with constitutive expression of activated Her2/Neu resulted i

34 Constitutive expression of AHR was affected by Nrf2 geno

35 -out of PTEN in dopamine neurons, leading to constitutive expression of Akt in these neurons.

36 eptor (alpha(1a)-247R) and demonstrated that constitutive expression of alpha(1a)-247R results in two

37 Here, we show that constitutive expression of alphaSyn in yeast impairs lat

38 cells lacking both p53 and pRb and that the constitutive expression of an active H-Ras oncogene in t

39 We also show that strong constitutive expression of an intron-containing JAZ10 ge

40 esis response, which in turn is regulated by constitutive expression of angiogenic inhibitors like th

41 ved macrophages (BMDM) from BALB/c mice lack constitutive expression of any of the six murine ecto-AR

42 Constitutive expression of any Pitx isoform suppressed s

43 Conversely, targeting constitutive expression of AP-2alpha in AP-2-positive KM

44 ranscriptional reporter analysis suggest the constitutive expression of bbdA in MSH1.

45 RNA interference accelerates flowering, and constitutive expression of BBX19 delays flowering under

46 Follicular lymphoma (FL) is characterized by constitutive expression of Bcl-2 as a consequence of t(1

47 Constitutive expression of Bcl-2 did not rescue the diff

48 Constitutive expression of BCL6 mediates lymphomagenesis

49 ctor-1-dependent expression of BNIP3 and the constitutive expression of Beclin-1 and Atg5, and that i

50 Constitutive expression of BLyS was observed in neutroph

51 We demonstrate constitutive expression of both PSR mRNA and protein tha

52 five of the Glu304 loop residues resulted in constitutive expression of both TnrA- and GlnR-regulated

53 Moreover, constitutive expression of BT2 imparted resistance to bo

54 Constitutive expression of BT2 induces telomerase activi

55 A at the time of conditioning, together with constitutive expression of c-Jun and JunD, may contribut

56 Constitutive expression of C/EBPbeta LIP inhibited IFN-g

57 Together with constitutive expression of Cas9, this system achieves se

58 Conversely, enforced constitutive expression of CD62L on T(EM) did not endow

59 emia and myeloma cells and downregulated the constitutive expression of cell survival proteins.

60 gnificantly repressed in the mutant and that constitutive expression of chbC in the mutant successful

61 to exercise is lost in transgenic mice with constitutive expression of CHCHD4.

62 gene fusions may be pro-neoplastic owing to constitutive expression of chimeric gene products normal

63 We have shown previously that constitutive expression of CNTF prevents photoreceptor d

64 ced cCF10 is carefully controlled to prevent constitutive expression of conjugation functions, an ene

65 We report constitutive expression of corneal lymphatics that exten

66 Both mouse strains showed constitutive expression of corneal VIP protein and nerve

67 d not express Cry11A protein indicating that constitutive expression of cry11A may be problematic in

68 Constitutive expression of CXCL12 in human colorectal ca

69 opulations of innate CD8(+) T cells based on constitutive expression of CXCR3.

70 mined by RT-PCR and flow cytometry for their constitutive expression of CXCR4 and CCR7.

71 Furthermore, the constitutive expression of cyclin A2 appears to augment

72 Constitutive expression of Cyp1a1 throughout the body or

73 eticulocytes remained unexplained, given the constitutive expression of DARC during reticulocyte matu

74 of exogenous Zn, deletion of Zur results in constitutive expression of dksA2, and Zur binds specific

75 We confirmed the constitutive expression of Dusp9 at the protein level in

76 ed genes regulated in response to high-level constitutive expression of E2Fa and of CYCD3;1, but such

77 sted the cell cycle in G1/S phase, inhibited constitutive expression of E6, Cyclin D1, CDK4, pRb, and

78 In addition, we show that constitutive expression of either of the two positively

79 Constitutive expression of either RET9 or RET51 increase

80 ich PDF1.2 transcription was up-regulated by constitutive expression of ERF1 in a coronatine insensit

81 ed in DES-induced kidney carcinogenesis, (b) Constitutive expression of ETRG-1 in normal kidney tissu

82 We earlier reported on a mouse model that constitutive expression of EVI1 in the BM led to fatal a

83 Constitutive expression of FBPase and fructose-6-phospha

84 host could be engineered to produce FDMs via constitutive expression of fdmR1; FDM production in S. l

85 However, constitutive expression of fevR in an mglA mutant strain

86 C and PDGFRalpha(+) cells were identified by constitutive expression of fluorescent reporters.

87 Intriguingly, constitutive expression of fluorescently tagged PIP2;7 i

88 Constitutive expression of FoxM1 in AREG knockdown cells

89 enhanced accumulation of abscisic acid, the constitutive expression of genes encoding antibiotic pep

90 nscriptional start sites are associated with constitutive expression of genes involved in translation

91 We find that constitutive expression of GFP-AtSAUR19 bypasses the nor

92 Constitutive expression of GhPAO in Arabidopsis thaliana

93 Constitutive expression of GLI3 repressor in Ptch1-defic

94 Constitutive expression of GLS1 led to exposure of beta-

95 Constitutive expression of GPC1 causes DNA rereplication

96 conclusion that at homeostasis in the lungs, constitutive expression of granulocyte-macrophage colony

97 As expected, constitutive expression of HAI-2 suppressed the formatio

98 ogated vernalization responsiveness and high constitutive expression of heat- and cold-responsive gen

99 hat HNF4alpha plays an important role in the constitutive expression of hepatic UGT2B7, and CAR acts

100 first time a novel bicistronic HC-Ad driving constitutive expression of herpes simplex virus type 1 t

101 nic epithelium disruption of Vhl resulted in constitutive expression of HIF, which initiated an incre

102 In cultured adipocytes, constitutive expression of HIF-1alpha increased Angptl4

103 Constitutive expression of HIF1 alpha and HIF2 alpha has

104 Constitutive expression of high levels of IL-12 receptor

105 mosome loss, all of which were suppressed by constitutive expression of histone H3 (delta 16H3).

106 in donors on suppressive ART consistent with constitutive expression of HIV RNA in infected cell clon

107 Constitutive expression of HK2 and LDHA during different

108 Constitutive expression of HopAI with the RP27 or TrpC p

109 tivity, its steady-state mRNA levels, or the constitutive expression of house-keeping genes (e.g. Cl

110 Constitutive expression of Hoxa11 in murine fibroblasts

111 kout strain can be partially complemented by constitutive expression of hrpG, indicating that PhoP co

112 Constitutive expression of HSFA2 rescued the development

113 The constitutive expression of HsfB2b leads to severely redu

114 Constitutive expression of HSH2 in the B lineage at leve

115 Constitutive expression of HSP-16.2 could reduce amyloid

116 ansgenic C. elegans animals with high level, constitutive expression of HSP-16.2.

117 Transgenic constitutive expression of hsp70 in neurons, the primary

118 We also confirmed that constitutive expression of hspX slows growth in vitro, a

119 Our results show that constitutive expression of human COX-2 (hCOX-2) in hepat

120 rule pathway mutants are characterized by a constitutive expression of hypoxia response genes and ab

121 Constitutive expression of hypoxia-inducible factor (HIF

122 ied the core promoter region responsible for constitutive expression of hZip1 and demonstrated critic

123 atopoietic developmental potential exhibited constitutive expression of ID family genes and of transc

124 nate and adaptive immune system cells is the constitutive expression of ID proteins in the former and

125 Constitutive expression of Id2 in differentiating NSCs r

126 human influenza viruses, in part due to the constitutive expression of IFITM3 proteins.

127 Constitutive expression of igeR resulted in the reductio

128 In contrast, constitutive expression of IKK2 directly increased the a

129 Constitutive expression of IL-10 in macrophages abrogate

130 ither Plexin-B2 or Plexin-D1 on DCs leads to constitutive expression of IL-12/IL-23p40.

131 er individuals into two extremes: those with constitutive expression of IL-1beta, nucleotide metaboli

132 on and arterial stiffness; and those without constitutive expression of IL-1beta, who lack these char

133 me that a combination of viral infection and constitutive expression of IL-2, but not IFN-gamma or IL

134 ng immunohistochemistry and ELISA, we showed constitutive expression of IL-33 in murine pancreas and

135 Constitutive expression of IL-33 was not detected in blo

136 Although several cells display constitutive expression of IL-33, we showed previously t

137 The results indicate that constitutive expression of IL-7Ralpha alone was not enou

138 Constitutive expression of IL-7Ralpha did allow for slig

139 ethal bacterial challenge demonstrating that constitutive expression of IL-7Ralpha does not impair, o

140 We investigated whether constitutive expression of IL-7Ralpha on T cells increas

141 tting of melanoma cell lysates confirmed the constitutive expression of iNOS.

142 -AMP synthase-mediated signaling and reduces constitutive expression of interferon in macrophages fro

143 e 1 IFN production is directly linked to the constitutive expression of IRF7, the master transcriptio

144 bidopsis thaliana) is chlorotic and exhibits constitutive expression of its iron uptake responses.

145 ion of (i) a chemical signal controlling the constitutive expression of key competence genes, and (ii

146 Neural progenitors with constitutive expression of KLF4 fail to migrate and deve

147 However, constitutive expression of KrasG12D in granulosa cells d

148 Constitutive expression of Kruppel-like factor 3 (KLF3,

149 tation, leading to Cre-lox recombination and constitutive expression of LacZ from its promoter.

150 tion of the WAP-Cre gene, recombination, and constitutive expression of LacZ.

151 M. truncatula, respectively, in response to constitutive expression of LAP1, many of which are invol

152 The consequences of constitutive expression of large amounts of defective st

153 We report here that constitutive expression of Lrp [lrp(Con)] dramatically a

154 opment in rice vascular sheath cells through constitutive expression of maize GOLDEN2-LIKE genes.

155 itutively expressed in plants, and show that constitutive expression of MBF1c in soybean enhances yie

156 (MIC>1 mg/ml) triclosan resistance either by constitutive expression of MexAB-OprM, an efflux pump of

157 n the mgtA riboswitch that causes high-level constitutive expression of mgtA.

158 mors, such as melanoma, may acquire aberrant constitutive expression of MHC class II.

159 ulticytokine polyfunctionality; in contrast, constitutive expression of miR-17-92 promoted terminal e

160 Constitutive expression of miR-34a led to a block in B c

161 Constitutive expression of miR-487b abrogated Wnt signal

162 and complete rescue of invasiveness in vitro Constitutive expression of miR-92a-3p or inhibition of m

163 Here we show that constitutive expression of miR408 results in enhanced gr

164 pression, it is intriguing to speculate that constitutive expression of MR1 may be detrimental for ma

165 Constitutive expression of murine IL-15 in IL-15-transge

166 mposition of defense-induced lignin, whereas constitutive expression of MYB15 increases lignin conten

167 port can be restored to feuP mutant cells by constitutive expression of ndvA; likewise, the symbiotic

168 ystems are almost ubiquitous in metazoa, the constitutive expression of neuroglobin-like proteins str

169 Aberrant constitutive expression of NF-kappaB subunits, reported

170 Constitutive expression of NF?B partially rescues cell d

171 rsion of CO2 to CH4 by R. palustris required constitutive expression of nitrogenase, which was achiev

172 anking region of the NK1 partly accounts for constitutive expression of NK1 in BCCs but could not acc

173 Here we show that constitutive expression of Notch1 intracellular domain i

174 High constitutive expression of Nrf2 was found in many types

175 ion, which is critical for the high level of constitutive expression of NT/N in enteroendocrine cells

176 rent neurons to peripheral signals and their constitutive expression of orexigenic receptors and neur

177 If constitutive expression of orthologs of AGL15 is able to

178 t for the host acquired immune response, and constitutive expression of OspC results in spirochete cl

179 Constitutive expression of ospR alters pigment productio

180 we show that mice deficient in p100 but with constitutive expression of p52 in lymphocytes developed

181 eir littermates with only p100 deficiency or constitutive expression of p52 in lymphocytes developed

182 notype, constitutive callose deposition, and constitutive expression of pathogen response genes.

183 ompounds momilactones and phytocassanes, and constitutive expression of pathogenesis-related genes.

184 pocotyls specifically under short days while constitutive expression of PCH1 shortens hypocotyls inde

185 The constitutive expression of PD-L1 in the testis is an imp

186 Constitutive expression of PELI1 resulted in ligand-inde

187 In this study, however, constitutive expression of PER, and not CRY1, severely d

188 Furthermore, constitutive expression of PER2 in the brain and SCN of

189 In Petunia, constitutive expression of PhLHY depressed the expressio

190 s with PIII and PIV CIITA promoters indicate constitutive expression of PIII in MSCs and a switch to

191 on in steroidogenic cells may be due to high constitutive expression of PKCepsilon that renders them

192 Additionally, we found that constitutive expression of PLATZ1 in WT plants confers p

193 Constitutive expression of PP(i)-associated genes was co

194 of the rhizoid system in the moss P. patens; constitutive expression of PpRSL1 and PpRSL2 converts de

195 also observed that mutations that led to the constitutive expression of PrfA-dependent virulence gene

196 PO in steroidogenic cells may be due to high constitutive expression of protein kinase Cepsilon (PKCe

197 Following constitutive expression of reciprocal constructs, potent

198 alogs, WTM1 and WTM2, that greatly increases constitutive expression of RNR3-lacZ.

199 expression in opt3-2 plants resulted in the constitutive expression of root iron deficiency response

200 Constitutive expression of RPS19R62W in developing mice

201 Here we show that constitutive expression of RV-cyclin in the HCT116 colon

202 Retrovirally-mediated constitutive expression of S1PR3 led to suppressed cell

203 irectly tested the leukemogenic potential of constitutive expression of SALL4 in a murine model.

204 Also, we demonstrated that constitutive expression of SALL4 inhibited granulocytic

205 Moreover, constitutive expression of SAP2 or SAP5 in two distinct

206 The constructed deletion also resulted in constitutive expression of SCO1135 transcript, as well a

207 for their therapeutic use, demonstrated that constitutive expression of serine protease inhibitor 9 (

208 Here, we detected constitutive expression of several microRNAs (miRNAs) po

209 Although constitutive expression of several of these proteins was

210 Upon constitutive expression of SHH, breast cancer cells show

211 Here, using a Cre-lox system to drive constitutive expression of SHH, we identify the effects

212 normal breast cells, we observe a high level constitutive expression of SOCS2, SOCS3, SOCS5, SOCS6, S

213 We show that constitutive expression of SOCS6 protein in retinal neur

214 There was no change in the constitutive expression of Sox9 or bone morphogenetic pr

215 We report here that constitutive expression of soybean orthologs of the Arab

216 These results suggest that constitutive expression of Spry1 in chondrocytes results

217 vent loss of alpha2-6 sialylation, we forced constitutive expression of ST6Gal-I, and found that this

218 rexpression decreased STAT3 phosphorylation; constitutive expression of STAT3 reversed SPARC-mediated

219 Constitutive expression of TaABF1 in aleurone cells of i

220 Such constitutive expression of TaLsi1 or OsLsi1 resulted in

221 Constitutive expression of TDP-43 in the Drosophila comp

222 Constitutive expression of Tfcp2l1 at levels similar to

223 sistance to various drugs, we determined the constitutive expression of TG2 in 75 PDAC and 12 PDAC ce

224 contrast to ICAM-1, there is restricted and constitutive expression of the alpha(4)beta(1) ligand, V

225 Constitutive expression of the AtPep1 precursor gene PRO

226 mal translocations and amplification lead to constitutive expression of the B cell lymphoma 6 (BCL6)

227 ion factor CESTA (CES) can contribute to the constitutive expression of the C-REPEAT/DEHYDRATION-RESP

228 Constitutive expression of the chemokine CXCL12 by bone

229 Constitutive expression of the chimeric NPM/ALK fusion p

230 However, constitutive expression of the core replication proteins

231 neuroblastoma hybrid cell line which showed constitutive expression of the exogenous Nav 1.8, and en

232 tion of the hns and ler genes in EHEC caused constitutive expression of the fusion reporter protein.

233 in the Phom promoter (P*hom ), resulting in constitutive expression of the hom-thrCB operon.

234 g protein was inactivated, also resulting in constitutive expression of the hom-thrCB operon.

235 Constitutive expression of the inflammatory cytokine tum

236 We show that on naive CD8(+) T cells, the constitutive expression of the integrin alpha4beta7 that

237 uniform binding of each variant, indicating constitutive expression of the M1 epitope and antibody o

238 This observation demonstrates that the constitutive expression of the mce1 genes by M. tubercul

239 The constitutive expression of the mce1 genes in the mce1R m

240 y we found that IFN-gamma down-regulated the constitutive expression of the neonatal Fc receptor (FcR

241 se in Wld(s) mice was associated with robust constitutive expression of the nonsignaling CD200 molecu

242 ia (T-ALL), we studied T-ALL cell lines with constitutive expression of the NOTCH intracellular domai

243 uble delta-like 4 (sDll4)/Jagged1 (sJag1) or constitutive expression of the Notch1 intracellular doma

244 Constitutive expression of the Notch3 intracellular doma

245 erent NT/N mRNA isoforms, and high levels of constitutive expression of the NT/N gene.

246 hat results in Ser200 Leu substitution and a constitutive expression of the Pho regulon.

247 ns in vitro and is attenuated in vivo due to constitutive expression of the phosphate starvation-resp

248 Constitutive expression of the Polycomb complex member B

249 Further analysis identified constitutive expression of the proinflammatory cytokine

250 Here we describe constitutive expression of the protein tyrosine kinase B

251 Constitutive expression of the rate-determining enzyme h

252 ficantly increased salicylic acid levels and constitutive expression of the systemic acquired resista

253 Constitutive expression of the triABC operon was due to

254 cted vanS deletion mutation also resulted in constitutive expression of the van genes, suggesting tha

255 pression in transgenic mice and determine if constitutive expression of these genes is sufficient to

256 Constitutive expression of these mutants in zebrafish em

257 CD of the ileum are characterized by reduced constitutive expression of these peptides and, according

258 ediated knockdown of CCN1 down-regulated the constitutive expression of these profibrotic genes in IP

259 elial protein C receptor (EPCR) and that low constitutive expression of these regulatory molecules in

260 ver, the molecular mechanisms that allow the constitutive expression of this genetic region in neuron

261 Constitutive expression of this lipase in fat storage ti

262 Constitutive expression of tissue factor (TF) by cancer

263 Constitutive expression of TK1086 (surR) from a replicat

264 Furthermore, constitutive expression of TL on epithelial cells led to

265 Constitutive expression of TL1A in transgenic mice was a

266 We demonstrate that TM have a lower constitutive expression of TLR pathway-specific genes co

267 This HC-HA complex is produced by constitutive expression of TNF-stimulated gene 6 and end

268 d macrophage cell surface gp96 inhibited the constitutive expression of TNFalpha.

269 Constitutive expression of TnrA- and GlnR-regulated gene

270 Constitutive expression of tomato TIP2;2 in transgenic T

271 We show that constitutive expression of transforming growth factor-al

272 provides an additional benchmark for strong constitutive expression of transgenes in Chlamydomonas,

273 ermal gammadeltaT precursor cells due to the constitutive expression of transgenic CCR6 resulted in t

274 The constitutive expression of transgenic green fluorescence

275 Expression analysis revealed high constitutive expression of trout IL-17A/F2 in mucosal ti

276 The constitutive expression of trout TNF-alpha3 was generall

277 xication, which is attributed in part to the constitutive expression of two importers: the proton-dep

278 Moreover, the constitutive expression of type 1 fimbriae in UPEC cysti

279 Constitutive expression of type 1 fimbriae leads to repr

280 in CFT073 fim L-ON is not solely due to the constitutive expression of type 1 fimbriae on the surfac

281 While constitutive expression of type 1 fimbriae resulted in a

282 Constitutive expression of U1 during growth produced ~25

283 This was achieved by inducing high-level constitutive expression of UME6, a recently identified f

284 Constitutive expression of vTR in the chicken fibroblast

285 Constitutive expression of VvMYB4a and VvMYB4b in petuni

286 get gene, whiB, and that deletion of bldO or constitutive expression of whiB is sufficient to induce

287 We find that constitutive expression of wild type, but not mutant, HS

288 Constitutive expression of wild-type SlARF10 did not alt

289 Plants with high constitutive expression of WVD2 or other members of the

290 Constitutive expression of ySpdSyn enhanced intracellula

291 Constitutive expression or conditional activation of wil

292 suitability of different strategies--such as constitutive expression or graded response--for regulati

293 terference reduces hypocotyl length, and its constitutive expression promotes growth.

294 Vad1 activity on inductive mating medium by constitutive expression resulted in repressed levels of

295 In transient conditional and constitutive expression studies in tobacco leaves using

296 ant biotechnology toolkit beyond traditional constitutive expression systems.

297 TS transcription factor ETV2 for 2 weeks and constitutive expression the ETS transcription factors FL

298 As expected, PARP1 and GAPDH showed constitutive expression throughout all cell lines and ti

299 e quantified the effect of these features on constitutive expression, transcription factor binding an

300 an achieve high levels of both inducible and constitutive expression with up to an 80% reduction in s