ライフサイエンスコーパス: constitutive heterochromatin

1 Dm0), and, like Lamin, Wash associates with constitutive heterochromatin.

2 repeat arrays, may lead to the formation of constitutive heterochromatin.

3 rived of canonical telomeres but capped with constitutive heterochromatin.

4 vo establishment of domains with features of constitutive heterochromatin.

5 nuclear organization, especially at sites of constitutive heterochromatin.

6 s the cellular RNAi pathway with assembly of constitutive heterochromatin.

7 ion of histone H4K20, an epigenetic mark for constitutive heterochromatin.

8 dimethylation, separates CEN chromatin from constitutive heterochromatin.

9 to environmental stresses, to nucleation of constitutive heterochromatin.

10 ike those in unexpressed euchromatin and not constitutive heterochromatin.

11 petunia, does not predominantly localise to constitutive heterochromatin.

12 e inactive X and is excluded from regions of constitutive heterochromatin.

13 sgenes are strongly affected by proximity to constitutive heterochromatin.

14 of genes reside within regions classified as constitutive heterochromatin and activating influences o

15 s of repetitive DNA organized in the form of constitutive heterochromatin and associated with repress

16 In contrast to stably repressive, constitutive heterochromatin and stably active, euchroma

17 Trimethylated H3(K9) marks pericentromeric constitutive heterochromatin and the male Y chromosome,

18 ylated histone H4 that discriminates between constitutive heterochromatin and unexpressed euchromatin

19 entally regulated model of PRC1 occupancy at constitutive heterochromatin, and where BMI1 function in

20 In this review we discuss the mechanism of constitutive heterochromatin assembly, its dynamic natur

21 d gene loci and facilitates the formation of constitutive heterochromatin at centromeric and mating-t

22 characterized by a large centrally localized constitutive heterochromatin block and by the presence o

23 us, with one of the alleles localized to the constitutive heterochromatin block and the other one loc

24 matin domains that are localized around this constitutive heterochromatin block.

25 the methyltransferase SET-7) did not impact constitutive heterochromatin but partially rescued the s

26 ve X chromosome (Xa), DXZ4 is organized into constitutive heterochromatin characterized by a highly o

27 onal aspects of fHC that distinguish it from constitutive heterochromatin (cHC) and euchromatin (EC)

28 Therefore, the key constitutive heterochromatin determinants can dynamicall

29 chromatin assembly, our results suggest that constitutive heterochromatin domains use multiple pathwa

30 asmic transcription sites, nuclear speckles, constitutive heterochromatin domains, mitotic chromosome

31 ximal regions and H3K27me1 is diagnostic for constitutive heterochromatin elsewhere in the barley gen

32 Our results reveal that emergence of constitutive heterochromatin follows a stereotyped devel

33 We show here that BMI1 is required for constitutive heterochromatin formation and silencing in

34 nt with that of BMI1 for H2A(ub) deposition, constitutive heterochromatin formation, and silencing.

35 amic fashion with the molecular hallmarks of constitutive heterochromatin, H3K9me3 and H4K20me3.

36 reductions of H3K9me3 and DNA methylation in constitutive heterochromatin have been variously reporte

37 Constitutive heterochromatin (HC) is important for maint

38 stone H3 methyltransferase Suv39h1 away from constitutive heterochromatin; however, it does not affec

39 me3) undergoes genome-wide redistribution to constitutive heterochromatin in DCDC- or HP1-deficient m

40 omatin protein 1 (HP1) is a key component of constitutive heterochromatin in Drosophila and is requir

41 pora clarify interactions of facultative and constitutive heterochromatin in eukaryotes.

42 es to the stable association of SUV39H1 with constitutive heterochromatin in human cells.

43 n for chromatin-associated RNA in regulating constitutive heterochromatin in human cells.

44 ever, assumed that the PRC1 is excluded from constitutive heterochromatin in somatic cells based on w

45 s boundaries, and initiates the formation of constitutive heterochromatin in yeast.

46 This loss of constitutive heterochromatin is accompanied by an up-reg

47 Constitutive heterochromatin is an important component o

48 Constitutive heterochromatin is commonly associated with

49 Constitutive heterochromatin is marked by distinctive hi

50 Constitutive heterochromatin is traditionally viewed as

51 Constitutive heterochromatin is typically defined by hig

52 36); a site associated with the formation of constitutive heterochromatin, lysine 9 (H3K9); and a sit

53 h1 known exclusively as a factor involved in constitutive heterochromatin maintenance, actively parti

54 so show a down-regulation of the pericentric constitutive heterochromatin mark, histone H3 trimethyla

55 model organism bearing both facultative and constitutive heterochromatin, Neurospora crassa, to expl

56 ating heterochromatic regions, including the constitutive heterochromatin on repetitive sequences nea

57 tor connecting the pluripotency network with constitutive heterochromatin organization in mouse embry

58 methylation levels in vivo demonstrate that constitutive heterochromatin organization is modified in

59 verall, our data reveal another function for constitutive heterochromatin proteins (the establishment

60 e and loss of silencing of reporter genes in constitutive heterochromatin regions.

61 Loss of H4K20me3 and H3K9me3 occurred at constitutive heterochromatin repeats.

62 ands-P, which are similar to facultative and constitutive heterochromatins, respectively.

63 untranscribed gene standards > D4Z4 arrays> constitutive heterochromatin (satellite 2; P < 10(-4) fo

64 mpared the physical properties of a 15.51-kb constitutive heterochromatin segment and a 16.17-kb facu

65 16, and Y, which consist of highly condensed constitutive heterochromatin, showed statistically signi

66 ching) are no more sensitive than the nearby constitutive heterochromatin that has previously been sh

67 cing at pericentromeric satellite sequences (constitutive heterochromatin), the maintenance of DNA me

68 omeres of most organisms are embedded within constitutive heterochromatin, the condensed regions of c

69 Yet, it is frequently constrained by constitutive heterochromatin, usually characterized by h

70 netic marks regulating either facultative or constitutive heterochromatin were examined.

71 is to package such sequences into so-called constitutive heterochromatin, where the dense chromatin

72 Unexpectedly, constitutive heterochromatin, which is generally associa