ライフサイエンスコーパス: constrain

1 quired or environmental controls are hard to constrain.

2 mobility within coke deposits remain poorly constrained.

3 nebular magnetic field and nebula are poorly constrained.

4 ts of these processes are complex and highly constrained.

5 migration upwards within the tidal frame is constrained.

6 HOCs, its affinity for PBDEs has been poorly constrained.

7 of the decarbonation processes remain poorly constrained.

8 er (OM) pools is often non-linear and poorly constrained.

9 ts long-timescale geologic history is poorly constrained.

10 barrier, where a head-to-head domain wall is constrained.

11 secondary organic aerosol (SOA) is not well constrained.

12 iyear dynamics of this feedback are not well constrained.

13 oes, but their formation rates remain poorly constrained.

14 ature of dyad activation and recruitment was constrained.

15 nitude of inland water OC burial is not well constrained.

16 of binding strength and being evolutionarily constrained.

17 ean, yet its composition has remained poorly constrained.

18 imescales (10(3)-10(5) years) remains poorly constrained.

19 hat most of the HEV genome is evolutionarily constrained.

20 Urban Cool Island (UCI) effect remain poorly constrained.

21 odes of internetwork failure propagation are constrained.

22 s of the world where financial resources are constrained.

23 Greenland and Svalbard, is currently poorly constrained.

24 cle Imaging (MPI) to humans is similarly PNS constrained.

25 distribution of COs during meiosis is highly constrained.

26 principle tells us which state variables to constrain?

27 tispecies two-box model inversion to jointly constrain 36 y of methane sources and sinks, using groun

28 sical observations from offshore Svalbard to constrain a coupled ice sheet/gas hydrate model, we iden

29 tesimals from the protoplanetary disk, would constrain a critical phase of planetary formation by unv

30 l loop establishes task-set selection, which constrains a more posterior loop responsible for respons

31 ling their limbs using a small set of highly constrained actuators.

32 nal reporter assay, we observed that several constrained agonists generated by a cycloaddition reacti

33 and the value of using predictive models to constrain analysis.

34 ab initio approach, relying on the strongly constrained and appropriately normed (SCAN) density func

35 generalized gradient approximation, strongly constrained and appropriately normed (SCAN).

36 trated that the proton depletion zone may be constrained and controlled by the addition of a finite a

37 specific classes of TFs, with both spatially constrained and flexible grammars.

38 m (called constrained projection) to two non-constrained approaches including CIBERSORT and a method

39 luoride-contaminated groundwater in resource-constrained areas.

40 and large-scale data acquisition in resource-constrained areas.

41 ains leading to the extinction remain poorly constrained as Late Devonian stratigraphy is poorly reso

42 power radiated through this mechanism is ill constrained, as the lower limit of the electron energy d

43 ration with temperature, but acclimation was constrained at high temperatures.

44 ggest that microdomains and the cytoskeleton constrain AtHIR1 dynamics, promote AtHIR1 oligomerizatio

45 The resulting model circuit is thus fully constrained biologically and provides a functional inter

46 anada's Yukon and identified the oldest well-constrained bison fossil in North America, a 130,000-y-o

47 Constrained bNAb escape, together with evidence of conte

48 species' phenologies and relative abundances constrained both total interaction turnover and rewiring

49 A systematic data set allows for constraining both thermal conductivity and equation-of-s

50 ve been used to argue that the small, highly constrained budding yeast chromosomes could not have the

51 thm to follow syllabic rhythms in speech, or constrained by a more endogenous top-down mechanism, e.g

52 ng that abstract context representations are constrained by an intrinsic functional architecture.

53 ation in LL emerges from carbon optimisation constrained by both leaf structural traits and abiotic e

54 l composition of Earth's lower mantle can be constrained by combining seismological observations with

55 the diversification of prochlorosins is not constrained by commensurate changes in the biosynthetic

56 However, HDR efficiency is constrained by competition from other double-strand brea

57 epatitis (NASH), but their widespread use is constrained by dose-limiting side effects thought to be

58 by any of the interactions, although it was constrained by drought (-18%).

59 find that the maximum potential of NCS-when constrained by food security, fiber security, and biodiv

60 been applied in ecology to make predictions constrained by just a handful of state variables, like t

61 rstanding of wetlands' services is currently constrained by limited knowledge on their distribution,

62 ively possible that the domain locations are constrained by low-level properties such as end-stopping

63 getic resources in hypoxic tumor regions are constrained by low-yielding glycolysis, and any means of

64 ADW and AABW and their properties are poorly constrained by marine records, including delta(18)O of b

65 However, such analyses are poorly constrained by measured CO2 exchange in drylands.

66 phy and optical coherence tomography, remain constrained by non-quantitative examinations and individ

67 e adults do-a behavioral profile that may be constrained by ongoing maturation of corticostriatal con

68 ng the catalytic nanoparticles themselves is constrained by other concerns.

69 larly with stadial intervals, remains poorly constrained by paleoclimate records.

70 novel phenotypes are also contingent on and constrained by parental genotypes.

71 al defense of nectar is, however, ultimately constrained by pollinator gustatory sensitivity.

72 Constrained by previously measured intracellular respons

73 ding in fungi, plants, and other lineages is constrained by reliance on base-contacting residues for

74 of assuring the safety of medical devices is constrained by reliance on voluntary reporting of advers

75 hich the modern phytoplankton environment is constrained by seasonal sea ice.

76 ide variants (SNVs) and indels from cfDNA is constrained by several factors such as the sequencing er

77 tational model of the healthy basal ganglia, constrained by single unit recordings from non-human pri

78 -state and transient properties of chromatin constrained by some physical properties embedded in 5C d

79 ics pipelines for analysis of these data are constrained by the availability of accurate and comprehe

80 Their evolution is necessarily constrained by the consequent challenge to protein foldi

81 ctive evaluation of human BAT stimulators is constrained by the current standard method of assessing

82 ine realm and knowledge of their function is constrained by the current understanding of fungal distr

83 he top 20 meters the V S models that is well constrained by the data, we obtain time-lapse repeatabil

84 Testing either model has been constrained by the diffraction limit of light microscopy

85 Constrained by the disulfide, conformational selection b

86 to noradrenergic arousal circuitry have been constrained by the fundamental inaccessibility of the hu

87 inate as antagonisms with parasite dispersal constrained by the host.

88 Although evaluation of this hypothesis is constrained by the limitations of the sea-ice cover reco

89 ional stochastic simulations with parameters constrained by the literature, we predict the cortical a

90 These events may be physically constrained by the plasma membrane.

91 rop, the development of cassava is seriously constrained by the rapid post-harvest physiological dete

92 loading, reductive dissolution appears to be constrained by the rapid transformation of schwertmannit

93 ntaining multiple wind arrays is, therefore, constrained by the rate of kinetic energy replenishment

94 These studies were constrained by the relatively small samples sizes and th

95 widely adopted tool in biotechnology, but is constrained by the requirements for colorimetric or tag-

96 y haze: (1) the dispersal of water vapour is constrained by the shallow PBL, leading to an increase i

97 model permits exploring transient properties constrained by the statistics of the 5C data.

98 lowing particles through a porous medium are constrained by the types of materials or exposure scenar

99 g site and the stem region on HA is severely constrained by their functional roles in engaging the ho

100 tries' advancement towards global targets is constrained by their health system's assumed absorptive

101 e directly with patients but report they are constrained by time or workload.

102 distribution has repeatedly been found to be constrained by warm temperatures, so we used Niche Mappe

103 between two fibroblasts; strand dynamics is constrained by ZO-1 binding.

104 ound to stimulate CAR homodimerization, thus constraining CAR in its inactive form.

105 ments and we now find that this is caused by constrained cDNA-ends, which can result from the sequenc

106 ide structural integrity, but also spatially constrain cells, and must therefore be modified to allow

107 stress and damage accumulation, effects that constrain cellular growth and transformation.

108 centromeres support centromere function and constrain centromere positions.

109 is mechanism ensures accurate segregation by constraining chromosome motion following biorientation o

110 These findings constrain cognitive models of language comprehension by

111 atomy, we show that realistic input patterns constrain combinatorial diversity by producing redundant

112 Conformational studies revealed a constrained conformation for this linear peptide.

113 peratures in the northern GBR may already be constraining coral growth and reef resilience.

114 fic to reactivated memories only, temporally constrained, cue-specific, long-lasting, and persist fol

115 We then test the performance of the constrained de novo method for homology modeling and rig

116 om rivers are currently derived using poorly constrained default IPCC emission factors (EF5r) which y

117 Conformationally constrained derivative 36 emerged as the most potent ana

118 PA-stabilized DNA bubbles within torsionally constrained DNA to investigate the annealing action of H

119 evolution of Arctic amplification is poorly constrained due to lack of continuous sediment proxy rec

120 However, these constants are often poorly constrained due to nearly complete removal of the solute

121 ops touch both the Watson and Crick strands, constraining duplex DNA in a bent configuration.

122 ns and flow rates because the two dimensions constrain each other.

123 ement signatures during the 1st year of life constrain early development in 71 healthy typically deve

124 eliothinae suggest that architecture may not constrain ecological adaptation in this group.

125 ation of negative regulatory programs, which constrain effector T cell expansion and prevent increasi

126 However, two bottlenecks constrain efforts towards fast imaging of large populati

127 l as a higher intrinsic rate constant in the constrained environments compared with water.

128 Antibodies directed against the four highly constrained epidermal growth factor (EGF)-like domains o

129 (Tribolium castaneum), we either allowed or constrained evolution of populations colonizing a novel

130 ce alters the fate of migrants to promote or constrain evolutionary divergence between populations.

131 s in fitness between individuals and thereby constrain evolutionary dynamics.

132 and 65.4% of the variance in exploratory and constrained exploratory models, respectively.

133 We constrain fault slip-rates since 18 ka using variations

134 ous studies on cracked plates and shells, we constrained flat elastic sheets to adopt fixed curvature

135 al framework where patterns in ecology embed constrained fluctuations.

136 tact and fractured rocks, forming a basis to constrain fluid flow in volcanic and geothermal systems.

137 from single cell proteomics distributions to constrain fluxes through a genome-scale model of metabol

138 tures providing contact guidance cues induce constrained focal adhesion maturation and associated F-a

139 ication into the foreseeable future, further constraining forest C fixation and potentially storage.

140 ecisions are complex because initial choices constrain future options.

141 It combines the constrained Gaussian mixture model that incorporates the

142 unctional MRI, we investigated the effect of constraining gaze in the eye-region during dynamic emoti

143 Surprisingly, a relatively constrained gene expression pattern is observed in brain

144 olidation of precise contextual memories and constrains generalized fear responses.

145 variation in the expression level of highly constrained genes.

146 ovides the best-resolved and most accurately constrained geochronology of any proxy from South Americ

147 since these are networks that are spatially constrained, geometrical properties play a fundamental r

148 These records constrain global paleoclimate reconstructions and inform

149 illustrates the potential of mechanistically constrained global fitting of binding data to yield the

150 (5-9 years), when infection and malnutrition constrain growth, and mortality is higher than previousl

151 state that likely plays an important role in constraining HIV-1 transmission and contributes to defin

152 First, we observed a constrained, horseshoe-shaped substrate pocket, formed f

153 l voltage response signals in live brains is constrained in depth by the optical diffusion limit, whi

154 ersibility of reactions is thermodynamically constrained in modern metabolic networks.

155 or activating conditions tropomyosin is not constrained in one structural state, but rather is distr

156 c and terrestrial carbon cycle remain poorly constrained in space and time.

157 he same stimuli seen freely or with the gaze constrained in the eye-region.

158 agency interventions have been criticised as constraining individual choice.

159 The retinal chromophore sterically constrained inside rhodopsin proteins represents an outs

160 mportant facets of this neural activity that constrain its possible roles in active social signaling,

161 detected a large ultralow-velocity zone and constrained its shape to be axisymmetric to a very good

162 features using fMRI data and an anatomically constrained Kuramoto model.

163 language development and object knowledge in constrained laboratory settings, but also allows researc

164 ng to a lack of palaeo-records with which to constrain levels of atmospheric oxidants during past cli

165 Signaling through FGFR1 is also required to constrain levels of the pluripotency-associated factor N

166 Global climate change is likely to constrain low latitude range edges across many taxa and

167 of the Holocene and the last millennium and constrain LUC emissions.

168 also impacted sexual selection indirectly by constraining mating assortment through the saturation of

169 lates Notch activation by a spatiotemporally constrained mechanism.

170 fear conditioning suggests that FTO normally constrains memory formation.

171 However, time constrained migrants should be less selective, balancing

172 using erosion rates of ancient watersheds to constrain Mio-Pliocene climatic conditions in the south-

173 Constrained mobility was maintained even when inhibiting

174 We use the experimentally constrained model to evaluate the correction factor (Phi

175 e how multifactor experiments can be used to constrain models and to identify a road map for model im

176 em (GPS) vertical deformation time series to constrain models of monthly hydrospheric loading and the

177 ermodynamic processes, while mechanistically constrained models enable hypothesis testing and identif

178 nd identified functional or biosynthetically constrained modules.

179 tic terminals within the EC and in this way, constrain non-action potential-dependent and action pote

180 -ERBIN-SMAD2/3 complex formation and fail to constrain nuclear pSMAD2/3 in response to TGF-beta.

181 ed as multiple lobes that establish a highly constrained nuclear environment.

182 parisons indicated that active-site residues constraining octane for omega-hydroxylation are conserve

183 Where one looks within their environment constrains one's visual experiences, directly affects co

184 Global sensitivity analysis and constrained optimization determined the set of parameter

185 Yet, the causes that constrain organic C accumulation in Oxisol soil are not

186 n-weathering illite from saprolitic remnants constrains original basement exposure in the Late Triass

187 nt strategies and policies as they seriously constrain our ability to identify relevant conservation

188 spheric oxidants to climate change is poorly constrained owing to large uncertainties in the degree t

189 cal PD neuron, measured in voltage clamp, to constrain parameter values of a conductance-based model

190 macrocyclization approach for the design of constrained peptide inhibitors having non-helical or ext

191 y, we developed the first reported series of constrained peptide nuclear import inhibitors.

192 The design of constrained peptides is of prime importance in the devel

193 Low phosphate (Pi) availability constrains plant development and seed production in both

194 gakaryocytes following platelet shedding and constrains platelet lifespan in the circulation.

195 sidases, however, has been hindered by their constrained pocket-shaped active sites.

196 , as well as a range of other enzymes having constrained pocket-shaped active sites.

197 f threonine 153 (T153) in Kir7.1 that reduce constrained polarity at this site (T153C, T153V, T153S)

198 These discrete extreme climatic events can constrain populations and space use at fine scales beyon

199 n natural fertility, indigenous, more energy constrained populations facing greater trade-offs in ene

200 Constraining predictions at ecologically relevant spatia

201 complexity of the underlying mechanisms has constrained previous studies to spherically symmetric co

202 We conclude that the widely-used constrained projection technique may not always be optim

203 of-the-art reference-based algorithm (called constrained projection) to two non-constrained approache

204 spirobis[chromene] intermediate possessing a constrained propylenic bridge between carbons 3 and 3' w

205 factors are largely uncertain due to poorly constrained proxy records.

206 Using optimal control theory to constrain reaction-diffusion schemes that are dependent

207 ence in EWAS may benefit from the use of non-constrained reference-based cell-type deconvolution meth

208 ds harbor a missense mutation localized to a constrained region of SMCHD1 encompassing the ATPase dom

209 tion for applications in small or physically constrained regions of the body.

210 ors designed to interact with evolutionarily constrained regions of the protease, while avoiding inte

211 gement, all of which occur within physically constrained regions.

212 e a new framework, Logistic Multiple Network-constrained Regression (LogMiNeR), and apply it to under

213 We propose a network constrained regularization method to select important SN

214 rowth and water use efficiency could further constrain responses to forecasted warming and drying.

215 e NAc that inhibit mesolimbic DA release and constrain reward-driven behavior.

216 electron microscopy demonstrated that AKAP79 constrains RII-C subassemblies within 150 to 250 angstro

217 Predicting and constraining RNA virus evolution require understanding t

218 e Robinson-Foulds Supertree problem within a constrained search space.

219 We constrain seawater pH through time by accounting for the

220 conditions for plasma genotyping in resource-constrained settings, the field has gained substantial e

221 commended but poorly implemented in resource-constrained settings.

222 toring of HPV-associated cancers in resource-constrained settings.

223 and dry conditions during the growing season constrain silver fir and Scots pine growth, particularly

224 mory states per cell, which however has been constrained so far by issues affecting the long-term sta

225 in silica as a direct consequence of volume-constrained solidification of a material undergoing anom

226 (8 ngm(-3) to 302 ngm(-3)) and dual-isotope-constrained sources (19 to 73% contribution from biomass

227 ne these interactions in a bio-energetically constrained, spatially and temporally resolved model of

228 How climate constrains species' distributions through time and space

229 Here, we present adaptive Morphologically Constrained Spectral Unmixing (MCSU) algorithms that ove

230 Analysis of the DWI data using constrained spherical deconvolution-based tractography i

231 We utilize the constrained structure of tumor proliferation models to d

232 PDMS micropillars on non-flat, highly space-constrained substrate areas at in situ controllable heig

233 Drought is the main abiotic stress constraining sugarcane production.

234 tely 20 microns have shown that expansion is constrained, suggesting that microbubble echoes would be

235 at differ in their shape and the capacity to constrain supercoils and compact the DNA.

236 at it may be used as a strain marker in well-constrained systems.

237 cation rounds needed to perform the locality-constrained tasks of entanglement transformation and its

238 Overall, N:P ratios were more constrained than C:nutrient ratios for both litter and s

239 o close the promoter DNA binding channel and constrain the beta' clamp domain, but with an orientatio

240 rial in Winchmore, New Zealand, were used to constrain the Cd soil mass balance between 1959 and 2015

241 e titanium isotopic composition of shales to constrain the chemical composition of the continental cr

242 The aim of this paper is to constrain the chronology of the site by developing a lon

243 th Bacteria and Archaea, using these data to constrain the environment in which life formed.

244 precipitation dynamics, it can more directly constrain the heterotrophic component of Rs, but global-

245 of aromatic residues, which would spatially constrain the keratin 1/keratin 10 end domains to allow

246 Tiered learning utilizes this observation to constrain the learning space for ATC codes at a particul

247 nd that i) middle- and high-dose data do not constrain the low-dose response, and different dose-resp

248 Simulations demonstrate that these dynamics constrain the membrane organization into small pools of

249 Plain to guide our model development and to constrain the model parametrization.

250 Further process-based studies are needed to constrain the oceanic sink of PFAS.

251 We constrain the radioactively powered transient resulting

252 These trends constrain the ratio mu : GPP (= (CUEa x CUEh )/(1 - CUEe

253 Autotoxicity may constrain the resistance of S. altissima to an intermedi

254 using a matrix factorization formulation to constrain the set of reactions used to fill gaps in a me

255 as a feature of astrotactin maturation, and constrain the substrate sequences that are permissive fo

256 ssNAbs to maintain the N332 glycan may have constrained the bNAb escape pathway.

257 cortex in humans; vmPFC/mOFC) is involved in constraining the decision to the relevant options.

258 on tests based on a biallelic additive model constraining the effect of a single-nucleotide polymorph

259 c potential of atoms in natural materials by constraining the electrons in the two-dimensional surfac

260 to meet primate metabolic requirements, thus constraining the evolution of frugivory.

261 t of increased predictability to their prey, constraining the evolution of lateralization.

262 nt in the hyperarid Atacama desert of Chile, constraining the immediate increase in soil moisture and

263 zing the Master Chemical Mechanism v3.2, and constraining the model for conditions found at the Cape

264 Constraining the optimal models using these data unmaske

265 is neuron type, it contributes indirectly by constraining the parameters of ICa.

266 fficulty in culturing representative members constrains the characterization of behavioural and adapt

267 e-off between swimming speed and growth rate constrains the evolution of faster migration.

268 on-random distribution along the chromosomes constrains the landscape of potential genetic combinatio

269 erature compensation of photosynthetic rates constrains the long-term temperature dependence of GPP,

270 This chemostratigraphic trend constrains the onset of widespread nitrate availability

271 This finding constrains the possible contributions of the MD network

272 ach of the three magmatic pulses potentially constrains the recharge duration of a single pluton with

273 Therefore, these obstacles constrain their utilization at primary care clinics and

274 of potential competition over the apparatus constraining their capacity to coordinate actions.

275 f melanoma cells surrounded by keratinocytes constraining their proliferation.

276 Therefore, while molecular pre-patterning constrains their orientation and position, preservation

277 e to the dynamics of phonon transport, which constrain thermal conductivity (k) to decrease monotonic

278 atmospheric mole fractions and isotopes) for constraining these geological emissions have been associ

279 aomega, can interact with a wave over only a constrained time period Deltat inversely proportional to

280 ceous chondrites reveal that late accretion, constrained to a maximum of 0.5 +/- 0.2 per cent of Eart

281 cial network-based approaches in ecology are constrained to considering networks as static, despite s

282 atasets from large, complex genomes has been constrained to laboratories.

283 Our results show that when constrained to look in the eyes, individuals with ASD sh

284 The model is constrained to observations of long-lived species, meteo

285 variability is an important limiting factor constraining tree growth in tropical forests.

286 dimensional diffusion process to a spatially constrained, two-dimensional one.

287 Work remains to better constrain uncertainty of NCS mitigation estimates.

288 as modeled, the tertiary structure of RNA is constrained using an elastic network.

289 asin, Northwest China, down to 7 km depth is constrained using the anelastic strain recovery (ASR) me

290 wetland area consistent with observationally-constrained values, but substantially smaller per-area C

291 The decline in Rubisco constrained Vcmax and An for leaves developed at higher

292 ts exhibited near-optimal behaviour and in a constrained version of the hand task in which choices co

293 mit viral dissemination in the brain and may constrain virus-associated injury.

294 of tropical and subtropical drylands is well constrained, whereas soil moisture and ecological drough

295 y predictions compared to networks that were constrained with randomly shuffled constraints.

296 Fluid transport and release can be constrained with seismological data.

297 of NOx (NOx = NO + NO2) emissions is poorly constrained, with a large portion of the uncertainty att

298 However, their phase space remains constrained, with transition metal high-entropy alloys e

299 T lymphocytes (TILs) adapt to the metabolic constrains within the tumor microenvironment (TME) and t

300 ot been documented to occur, and (ii) poorly constrained zircon growth rates combined with the assump