ライフサイエンスコーパス: constriction

1 failure (HF) mice (HF induced by transaortic constriction).

2 knockout (IL10KO) mice by transverse aortic constriction.

3 s actin (f-actin) assembly, which drive ring constriction.

4 rate dysregulation after exposure and aortic constriction.

5 genes that regulate cell adhesion and apical constriction.

6 hronic pressure-overload by transverse aorta constriction.

7 ave subsequently undergone transverse aortic constriction.

8 on-muscle myosin II, which coordinate apical constriction.

9 ac hypertrophy triggered by transverse aorta constriction.

10 to encircle the division plane and complete constriction.

11 tal cell wall synthesis to ensure successful constriction.

12 rents (STOCs), events that moderate arterial constriction.

13 ng that the GTP energy is primarily spent in constriction.

14 g assembly and promotes timely onset of ring constriction.

15 ng 3 weeks before surgical transverse aortic constriction.

16 al displacements of helical turns related to constriction.

17 e identification of size quantization in the constriction.

18 e seen in HFpEF induced by transverse aortic constriction.

19 mooth muscle (VSM) cells, causing persistent constriction.

20 ring where nodes move bidirectionally during constriction.

21 nt for proper contractile ring formation and constriction.

22 terial and delays in both ring formation and constriction.

23 nsor that contributes to arteriolar myogenic constriction.

24 rents (STOCs), events that moderate arterial constriction.

25 ase ET-1 and initiate powerful ET-1-mediated constriction.

26 dilation after 28 days of transverse aortic constriction.

27 ulated GTP hydrolysis that promotes membrane constriction.

28 1 (ET-1) and initiates endothelium-dependent constriction.

29 s junctional components to facilitate apical constriction.

30 s peptidoglycan (PG) remodeling and envelope constriction.

31 size, followed by a pure adder phase during constriction.

32 lative lateral displacement of the turns and constriction.

33 e thought to play critical roles in membrane constriction.

34 ved from bone marrow after transverse aortic constriction.

35 ngiotensin-II infusion or transversal aortic constriction.

36 for sodium at the "GAS belt" in the central constriction.

37 wn of AT1 Rb selectively diminished myogenic constriction.

38 e contribution of FtsZ filament curvature to constriction.

39 amic steady-state prestress to large, pulsed constrictions.

40 of approximately 1.5 x 10(6) m s(-1) in our constrictions.

41 sess a mechanism to pass through micrometric constrictions.

42 ormation during transmigration through small constrictions.

43 ermions in lithographically defined graphene constrictions.

44 e assessment of pericardial inflammation and constriction; 3) given phenotypic similarities between r

45 n the DCM (40-fold) than in transverse aorta constriction (4-fold).

46 ver, after 7 to 28 days of transverse aortic constriction, a subset of cardiomyocytes in fibrotic are

47 Transverse aortic constriction activated FYN in the left ventricle (LV), a

48 pha-SMA phenotype mediates acute microvessel constriction after SAH possibly by hemoglobin suppressin

49 to generate contractile stresses during ring constriction, although a number of models have been prop

50 as moderate negative correlation between EZW constriction and age (rs = -0.532, P < .0001).

51 ranscriptional response to transverse aortic constriction and altered DNA methylation.

52 eyes (rs = 0.627, P = .0002) and between EZW constriction and baseline EZW (rs = 0.714, P < .0001).

53 se in orthogonal force allows premature ring constriction and cellularization, whereas the experiment

54 ve visual functions in people, such as pupil constriction and circadian photoentrainment.

55 We show that pupil metrics of constriction and dilation are distinct from baseline met

56 ole vascular tone, which result in arteriole constriction and dilation, respectively, altered resting

57 ents that occurred upstream of mitochondrial constriction and division machine assembly.

58 es of multiple autolytic enzymes during cell constriction and fission respectively.

59 rophy in mice subjected to transverse aortic constriction and improved cardiac function.

60 events such as convergent extension, apical constriction and interkinetic nuclear migration, as well

61 A major driver of apical constriction and junctional disassembly are periodic pul

62 a complete ring of FtsZ is not required for constriction and lead us to propose a model for FtsZ-dri

63 cter and ciliary muscle to mediate pupillary constriction and lens accommodation, respectively.

64 he vacuoles revealed that auxin controls the constriction and luminal size of the vacuole.

65 ological responses to light, e.g., pupillary constriction and neuroendocrine regulation.

66 Rho-kinase inhibitor Y-27632 reduced vessel constriction and PH in Pbx-mutant mice.

67 amic behavior in a microfluidic channel with constriction and quantify the biorheological properties

68 ked linear arrays oriented along the axis of constriction and restricted to a narrow zone within the

69 the site of ingression decreases throughout constriction and suggests that cytokinesis is accomplish

70 zed dynamic actomyosin networks drive apical constriction and the anisotropic loss of cell contacts d

71 roposed to be inhibitory to contractile ring constriction and thus specifically inactivated by CYK-4

72 ic devices designed to mimic human capillary constrictions and CTC clusters obtained from patient and

73 dition to spatial coupling between capillary constrictions and oxidative stressed neurons and neurode

74 pore-lining residues that cluster near pore constrictions and regulate channel gating.

75 uclei can be visualized while moving through constrictions and use it to elucidate mechanisms for nuc

76 a simple model of statistically distributed "constrictions" and "bridges" for displacements in the mi

77 when a mismatch is in proximity to the latch constriction, and by the loss of the two-state current s

78 duced in aortic SMCs after transverse aortic constriction, and Foxe3 deficiency increased SMC apoptos

79 chronic inflammation, oxidant stress, local constriction, and injury in trigeminal nerves may contri

80 al myosin-II Myp2 is most important for ring constriction, and type V myosin Myo51 aids the other two

81 cell shape as cells deform into microfluidic constrictions, and we calibrate the mechanical stresses

82 (e.g., Cas9, FokI), are depleted within the constriction, approaching 0%.

83 -driven anisotropic junction loss and apical constriction are the main drivers of this process.

84 in human erythroblasts, which do not have a constriction, arguing against a contractile ring-based n

85 ffect of AMPK activation in opposition to PE constriction as the result of both NO-dependent and NO-i

86 initial peptidoglycan synthesis and envelope constriction at the onset of cytokinesis, later increasi

87 ' at the intracellular entrance and a second constriction at the selectivity filter.

88 le events, we discovered that differences in constriction behavior are biased by initial cell shape.

89 ents resulting from intense Joule heating at constrictions between grains.

90 ncreased interspindle distances and cellular constrictions between spindle compartments.

91 al "purse-string" model for contractile ring constriction, but also suggest that the CR may be derive

92 ha12/13 pathway coordinate collective apical constriction, but the mechanism of coordination is poorl

93 ow relatively evenly during contractile-ring constriction, but the rim of the cleavage furrow is the

94 'no-reflow' has been attributed to capillary constriction by contractile pericytes.

95 e-producing actomyosin networks drive apical constriction by contracting while connected to cell-cell

96 h from the plasma membrane in the absence of constriction by dynamin.

97 ry becomes elevated in response to increased constriction by nurse cells.

98 uggest that ZipA and FtsA* may contribute to constriction by stabilizing this miniring conformation.

99 calmodulin enhanced membrane tubulation and constriction by wild-type Rvs167 but not calmodulin-bind

100 in DCM, and partially after transverse aorta constriction, by stabilizing myocardial NAD(+) levels in

101 ells' requirement for Arp2/3 to pass through constrictions can be relieved when nuclear stiffness is

102 Before cytokinetic ring constriction, Cdc42 activation, is Gef1 dependent, and a

103 r responses, a modest increase in adrenergic constriction combined with an elevated thromboxane A2 pr

104 cular fibrotic areas after transverse aortic constriction compared with sham-treated control subjects

105 domain probably terminates near the critical constriction control domain, which might correspond to a

106 vasculature in response to transverse aortic constriction, corresponding to decreased expression of t

107 of dural vessels, and the dynamics of these constrictions could be captured with a linear convolutio

108 individual RBC squeezes through a microscale constriction (cross-section 5micromx5microm).

109 nstrated significant brain arteriolar vessel constriction, decreased functional capillary density, an

110 Apical constriction depends on a Rho GTPase signaling pathway (

111 It is thought that coordinate mesoderm constriction depends on high levels of myosin along the

112 Dural vessel constrictions did not mirror the large increases in intr

113 Apical constriction drives tissue folding or cell extrusion in

114 critical mechanochemical GTPase that drives constriction during mitochondrial division.

115 ansmission) blocked dilatation and increased constriction during PNS.

116 20 cells successfully traversed 5- to 10-mum constrictions even in whole blood.

117 concert with Drp1 to orchestrate sequential constriction events that build up to division.

118 the flow through a viscous point contact, a constriction exhibiting the quantum mechanical ballistic

119 a separation device is presented featuring a constriction-expansion design, which produces 100.0% pur

120 several cancer cell lines drawn into narrow constrictions, f can easily increase locally to nearly 1

121 Consequently, the cytosolic constriction for Cl(-) passage is widened in CLC-K such

122 mutants with in vivo measurements of apical constriction for the same mutants, we show that in vivo

123 In a mouse model of transverse aortic constriction, galectin-3 expression was markedly up-regu

124 During neuronal delamination, acto-myosin constriction generates a tunnel-like actin-microtubule c

125 Migration through micron-size constrictions has been seen to rupture the nucleus, rele

126 studies of tissue folding, including apical constriction, have focused on how RhoA is activated by G

127 any functional decline in transverse aortic constriction hearts.

128 ending artery ligation and transverse aortic constriction HF mouse models after 4 and 8 weeks of foll

129 ther, Myosin-2 activity is required for slow constriction in "phase 1" but is largely dispensable for

130 phase 1" but is largely dispensable for fast constriction in "phase 2," and F-actin disassembly is on

131 mitochondrial calcium in turn activates IMM constriction in a Drp1-independent manner.

132 cture of intact dividing cells and show that constriction in a variety of Gram-negative bacterial cel

133 al link between FtsZ curvature and efficient constriction in C. crescentus.

134 ignment leading to fibrosis and renovascular constriction in diabetes.

135 Ca channel activity opposes pressure-induced constriction in human small resistance adipose arteries,

136 ressure overload resulting from trans-aortic constriction in mice leads to cardiac fibrosis and incre

137 continuous F-actin ring at the cell surface constriction in mouse erythroblasts, nor at the membrane

138 l stimulation with A23187 or thrombin caused constriction in P1 arteries, no significant change in di

139 -actin disassembly is only required for fast constriction in phase 2.

140 if AT1 R mechanoactivation affects myogenic constriction in skeletal muscle arterioles and to determ

141 by formation of smooth boundaries or apical constriction in small groups of cells.

142 hat Efnb3 gene knockout mice showed enhanced constriction in the carotid arteries.

143 point after ablation, but predominant tissue constriction in the caudal and ventral neural plate zone

144 ASICs has long been attributed to a central constriction in the channel pore, but experimental verif

145 implementation exploits a defect, such as a constriction in the magnetic track, that can serve as a

146 es that form an hourglass-shaped pore with a constriction in the middle of the membrane and a lateral

147 ific loss of beta-catenin after trans-aortic constriction in vivo.

148 male C57BL/6 mice model of transverse aortic constriction in which left ventricular hypertrophy occur

149 omotion but did not block locomotion-induced constrictions in dural vessels.

150 and the edges of ER cisternae and to induce constrictions in ER tubules when overexpressed, and iden

151 ntral ion pore, and the channel is closed by constrictions in the cytosol.

152 nitude of NG2+ mural-cell mediated capillary constrictions in the hippocampus of epileptic mice than

153 ical distribution of transport resistances ("constrictions" in the channels) and of shortcuts (connec

154 e direct effects of Syk inhibition on airway constriction independent of allergen sensitization remai

155 and integrins as novel regulators of apical constriction-independent cell elongation, as alpha-Spect

156 Together, the elevated airway constriction induced by cholinergic transmission in KO n

157 0KO chimeric mice) reduced transverse aortic constriction-induced BM-FPC mobilization compared with I

158 n in IL10KO mice inhibited transverse aortic constriction-induced cardiac fibrosis and improved heart

159 Parkin knockout mice exposed to aortic constriction-induced cardiac pressure-overload or in res

160 ation and neuropathic pain using the chronic constriction injury (CCI) model.

161 found that cold allodynia induced by chronic constriction injury (CCI) of the sciatic nerve in mice,

162 Chronic constriction injury (CCI) of the sciatic nerve induced I

163 ate phase neuropathic pain following chronic constriction injury (CCI), were reduced in CKO mice.

164 Furthermore, chronic constriction injury bilaterally augments nociceptive amy

165 In chronic constriction injury mice, these treatments remarkably su

166 used a rodent partial sciatic nerve chronic constriction injury model (n = 5-8 per group per experim

167 ehavioral hypersensitivity following chronic constriction injury to the infraorbital nerve (CCI-ION).

168 eptor antagonist PACAP(6-38) blocked chronic constriction injury-induced behavioral responses.

169 Apical constriction is a change in cell shape that drives key m

170 Apical constriction is a widely utilized cell shape change link

171 This constriction is blocked by fibrous organelles, structure

172 g it easier for the cell to divide when ring constriction is compromised.

173 When apical constriction is disrupted, compressing force generated b

174 It remains unclear how apical constriction is regulated spatiotemporally during tissue

175 factors during transmigration through small constrictions is still lacking.

176 ctivation, is Gef1 dependent, and after ring constriction, it is Scd1 dependent.

177 n evoked circadian phase resetting and pupil constriction (known consequences of mRGC activation).

178 ocess is controlled by cytosolic actin-based constriction machinery and dynamin-related protein 1 (Dr

179 suggesting that non-fully-developed flow and constriction may lead to demargination.

180 that optic cup morphogenesis is driven by a constriction mechanism and indicates that supra-cellular

181 pologically analogous to well-studied apical constriction mechanisms, but very different from them bo

182 ngular opportunity to compare separable ring constriction mechanisms, with varying Myosin-2 dependenc

183 of the MHB, the midbrain-hindbrain boundary constriction (MHBC), and are critical for proper MHB for

184 iling heart of both DCM and transverse aorta constriction mice that was accompanied by a decrease in

185 oreover, CMs isolated from transverse aortic constriction mice treated with MR-409 showed improved co

186 t failure was studied in an abdominal aortic constriction model of murine cardiac hypertrophy and hea

187 Twelve weeks post transverse aortic constriction, myocardial tissues were collected to evalu

188 ent either sham procedures (n = 8) or aortic constriction (n = 12) with a customized pre-shaped band.

189 transport and fluid secretion, smooth muscle constriction, neuronal excitability, and cell proliferat

190 neither loss of spatially coordinated apical constriction nor its complete blockage prevent internali

191 n animals, fungi, and amoebas depends on the constriction of a contractile ring built from a common s

192 most animal cell divisions and driven by the constriction of a contractile ring positioned and contro

193 The mismatch is held at the latch constriction of alpha-hemolysin, which is used to monito

194 duplex is situated in proximity to the latch constriction of alphaHL during DNA residence inside the

195 itively charged lysine residues at the latch constriction of alphaHL.

196 Cytokinesis is driven by constriction of an actomyosin contractile ring that is c

197 Cytokinesis in animal cells requires the constriction of an actomyosin contractile ring, whose ar

198 the mitotic spindle governs the assembly and constriction of an actomyosin ring.

199 This type of folding is characterized by constriction of apical cell surfaces, and the resulting

200 increases TRPM4 currents to induce myogenic constriction of cerebral arteries.

201 we found that voluntary locomotion drove the constriction of dural vessels, and the dynamics of these

202 a ventral furrow and other epithelia, apical constriction of hundreds of epithelial cells folds the t

203 d VEGF-D translation along with a subsequent constriction of lymphatic vessels in tumors.

204 Here we report spontaneous and repetitive constriction of mitochondrial inner compartment (CoMIC)

205 with widespread disease presented with more constriction of peripheral visual fields and had more dy

206 microscopy imaging analysis to visualize the constriction of single dynamin-coated membrane tubules.

207 The constriction of the Central American Seaway reached a cr

208 in isoforms participate in the formation and constriction of the contractile ring in fission yeast.

209 Different from animal cells that divide by constriction of the cortex inward, cells of land plants

210 s both initiation of cell division and final constriction of the cytokinetic ring.

211 This study provides a novel example of the constriction of the dietary niche of a successful invasi

212 eld, they also reveal significant unexpected constriction of the functional field.

213 Subsequently, between 4-3 Ma, the constriction of the Indonesian Seaway impacted regional

214 trend, with possible contributions from the constriction of the Indonesian Seaway.

215 the inner pore (hydrophobic gating) and (2) constriction of the inner pore by tight criss-crossing o

216 eation pathway of the channel is closed by a constriction of the inner pore formed by criss-crossing

217 hway of these channels is closed by a single constriction of the inner pore formed by the criss-cross

218 shape changes occur at the point of deepest constriction of the MHB, the midbrain-hindbrain boundary

219 ng and inward membrane buckling, followed by constriction of the nascent bud neck and ultimately ILV

220 e-scale structural change and a local steric constriction of the pore.

221 the pupil light reflex (PLR): the automatic constriction of the pupil in response to luminance incre

222 onmuscle myosins is required for appropriate constriction of these contractile rings.

223 lix abolishes the ability of RTN13 to induce constrictions of ER tubules in vivo.

224 ET-1 caused similar concentration-dependent constrictions of P1, P7 and P21 arteries.

225 ectrical transport in suspended atomic-scale constrictions of single and multilayer graphene created

226 A temporal mismatch between the constriction or dilation of the blood vessel lumen and t

227 This record suggests abandonment, severe constriction, or local extinction followed by subsequent

228 nature of the melanopsin-mediated persistent constriction phase of the pupillary light reflex may rep

229 The melanopsin-mediated, sustained pupillary constriction phase response following cessation of a blu

230 ed with the photoreceptor-mediated pupillary constriction phase response following cessation of a red

231 tion of Meg3 in vivo after transverse aortic constriction prevented cardiac MMP-2 induction, leading

232 f disintegrating, ring topology recovers and constriction proceeds.

233 he ring to the plasma membrane, trigger ring constriction, produce force to form a furrow, disassembl

234 n for the same mutants, we show that in vivo constriction rate scales with myosin motor activity.

235 We observed that FzlA influences constriction rate, and that this activity is associated

236 Strong correlations were found between EZW constriction rates of right and left eyes (rs = 0.627, P

237 EZW constriction rates were 176.6 +/- 130.1 mum/year and 173

238 ences in their binding sites situated in the constriction region.

239 tan, indicating that AT1 R-mediated myogenic constriction relies on Ca(2+) -independent downstream si

240 r, the coupling between cell size, shape and constriction remains poorly understood.

241 In vessels, these factors enhance constriction, remodeling, and rarefaction.

242 bated: GTP energy could be spent in membrane constriction required for fission, or in disassembly of

243 IMM constriction requires electron transport chain activity.

244 the melanopsin-mediated sustained pupillary constriction response was significantly associated with

245 the melanopsin-mediated sustained pupillary constriction response.

246 e initiation of nucleoid separation and cell constriction, second and third zones of elongation are e

247 mouse hearts 1 week after transverse aortic constriction showed comparable increases in fibrotic gen

248 on in cardiac fibroblasts after trans-aortic constriction significantly preserves cardiac function, a

249 simulations to pull Ca(2+) through the pore constriction site of a closed-channel RyR1 structure det

250 axis and twisting of Ile-4937 at the channel constriction site out of the channel pore.

251 aM to the pore-gating residues of the second constriction site.

252 utations around the closed- and open-channel constriction sites (Gln-4933 and Ile-4937).

253 ecruitment, and the formation of microtubule constriction sites.

254 sses, our model predicts the lower bounds of constriction size for successful transmigration.

255 red for an individual cell to pass through a constriction smaller than the cell size.

256 developments, we have adapted a microfluidic constriction sorter device to separate a wide range of n

257 We show that these phases differ in constriction speed and are genetically and pharmacologic

258 hown to proceed with at least two sequential constriction steps: the endoplasmic reticulum and actin

259 Surprisingly, this mutant inhibits constriction, suggesting that centrally localized apical

260 and actin must first collaborate to generate constrictions suitable for Drp1 assembly on the mitochon

261 cal development induced by transverse aortic constriction (TAC) or isoproterenol infusion.

262 ed pressure overload by transthoracic aortic constriction (TAC) or volume overload by aortocaval shun

263 e-overload-induced HF with transverse aortic constriction (TAC) surgery and compared among 4 study gr

264 Mice underwent transverse aortic constriction (TAC) surgery and deoxycorticosterone aceta

265 mmation and fibrosis after transverse aortic constriction (TAC) surgery, a pressure-volume overload m

266 scle hypertrophy caused by transverse aortic constriction (TAC) to determine SIRT5's role in cardiac

267 ent of heart failure after transverse aortic constriction (TAC) using global and T-cell-specific CD73

268 eased pressure load due to transverse aortic constriction (TAC).

269 hronic pressure-overload by transverse aorta constriction (TAC).

270 ischemic hypertrophic CHF, transverse aortic constriction (TAC).

271 s less potent in stimulating mouse-eye pupil constriction than muscarinic agonists oxotremorin-M (Oxo

272 d to result from opening of an intracellular constriction that prevents ion entry into the pore.

273 ve mesoderm cells exhibit coordinated apical constrictions that mediate invagination [5, 6].

274 pushes or pulls its nucleus through a small constriction, the chromatin must distort and somehow mai

275 By 6 weeks transverse aortic constriction, the metabolic profile reversed with impair

276 e FzlA as a critical coordinator of envelope constriction through its interaction with FtsZ and sugge

277 comparable to LZR for most stimuli, although constriction to alpha1 -adrenoreceptor stimulation was e

278 tor disorders, such as paradoxical pupillary constriction to darkness, benign tonic upgaze of infancy

279 In P1 arteries, constriction to thrombin or A23187 was inhibited by endo

280 n and collagen deposition after trans-aortic constriction.Understanding the mechanisms causing cardia

281 After gap repair, an increase in constriction velocity allows cytokinesis to complete at

282 ity in response to 2 weeks transverse aortic constriction versus sham, linked to enhanced insulin sig

283 For example, widespread vessel constriction (vessel tone) is induced by brainstem neuro

284 nt with functional relevance of this motion, constriction via inter-subunit cross-linking reduces tra

285 ow that it proceeds in three stages: a local constriction ("waist formation"), pulsation-which increa

286 ing locomotion, indicating that dural vessel constriction was not caused passively by compression.

287 erivascular fibrosis after transverse aortic constriction, when compared with mock- or dominant-negat

288 aggravated fibrosis after transverse aortic constriction, when compared with wild-type control subje

289 ode of growth: a relative timer phase before constriction where cell growth is correlated to its init

290 to the cytokinetic ring and promotes timely constriction, whereas Scd1 localizes later to the ingres

291 me required for a cell to deform and enter a constriction, which is dominated by the deformability of

292 the fully deformed cell to travel inside the constriction, which mainly relies on the surface frictio

293 Similarly, arteriolar constriction with phenylephrine (PE) (10(-5) m) induced

294 ve crabs triggered significant dietary niche constriction within the invasive crayfish population.

295 It is unclear, however, how dynamin helix constriction works.

296 w that the antibiotics must pass through the constriction zone of porins with a specific orientation,

297 ibiotic in an unfavorable orientation in the constriction zone that suffers steric hindrance for the

298 he water-filled channel of MOMP has a narrow constriction zone, and single-molecule studies show a mo

299 The ion neutralizes negative charges at the constriction zone, reducing the transverse electric fiel

300 ructure has identified a Ca(2+) bound at the constriction zone, which is functionally significant as