ライフサイエンスコーパス: context-dependent

1 eakly dominant negative or their effects are context dependent.

2 r suppressor or oncogenic activity is highly context dependent.

3 ted by the arrangement of AT groups, i.e. is context dependent.

4 resistance levels, suggesting that they are context dependent.

5 show that BTK-dependent signaling is highly context dependent.

6 and show that the regulatory role of BRA is context dependent.

7 vity of IFN-gamma on murine hematopoiesis is context dependent.

8 te the importance of breeding individuals is context dependent.

9 targets of YAP have been shown to be highly context dependent.

10 local hemodynamics is not fixed, but rather context dependent.

11 stimuli are fixed, but sensory perception is context dependent.

12 rate that effects of these drivers should be context-dependent.

13 and usefulness of individual methods remain context-dependent.

14 nt suggest that these control mechanisms are context-dependent.

15 nd distances by scatter-hoarding corvids are context-dependent.

16 302-His-305 salt bridge are thus complex and context-dependent.

17 tation, innate odor-induced behaviors can be context-dependent.

18 ophyte effects on plant disease severity are context-dependent.

19 riority of one NA category over the other is context-dependent.

20 mplies that incentive value is intrinsically context-dependent.

21 slocation, implying that the process is cell context-dependent.

22 anterior piriform cortices is learning- and context-dependent.

23 at taste coding is dynamic, distributed, and context-dependent.

24 lthough whether WGD is beneficial is clearly context-dependent.

25 can be both Tel1-independent and chromosomal context-dependent.

26 Our study unveils the dual and context-dependent action of IND, a drug that serves both

27 rising observations previously attributed to context-dependent action of these signals.

28 The context-dependent activation of ARF did not affect growt

29 eural basis of the decoy effect could be the context-dependent activation of the valuation area.

30 and gene expression profiles for extracting context-dependent active subnetworks.

31 iments in frog embryos, for spatiotemporally context-dependent activity of Ptf1a as a potent gain-of-

32 a Tie2 agonist, whereas Ang2 functions as a context-dependent agonist/antagonist.

33 based machine-learning classification with a context-dependent algorithm for selecting splice variant

34 Auxin responses are highly context dependent and can involve changes in cell divisi

35 f basic residues to binding affinity is also context dependent and cannot be approximated by a rule-o

36 This role is context dependent and is determined by which of the two

37 gnaling in specific circuits of the brain is context dependent and selectively recruited.

38 he relative balance of these factors will be context dependent and so help explain why the pattern of

39 esistance, the specific changes involved are context dependent and thus inherently unpredictable.

40 n oncogenes and tumor suppressors are highly context-dependent and are predominantly linked to differ

41 The effects of Notch signaling are context-dependent and both oncogenic and tumor-suppressi

42 Aggression in Drosophila is context-dependent and can thus be expected to involve in

43 Notch activity regulates tumor biology in a context-dependent and complex manner.

44 lation of neuronal activity by locomotion is context-dependent and contest the generality of a disinh

45 can differentially control the formation of context-dependent and context-independent forms of rewar

46 trans-effects on inflammatory signaling are context-dependent and influenced by nuclear receptor con

47 rnative: sensitivity to 3D motion signals is context-dependent and must be learned based on explicit

48 p between TGFbeta signaling and autophagy is context-dependent and remains unclear.

49 The effects of OT are context dependent, and it has been proposed that OT incr

50 s how the concept of "random" differences is context dependent, and propose that rigorous definitions

51 M-mediated somatic embryogenesis is dose and context dependent, and the context-dependent phenotypes

52 s in human speech, categorical perception is context-dependent, and as is the case for human phonolog

53 hat symbionts exert on their hosts are often context-dependent, and existing theoretical frameworks o

54 ions, Wnt/beta-catenin signaling is complex, context-dependent, and highly regulated.

55 The activity of these reagents is often context-dependent, and the parameters that impact cell e

56 etween storing paths in de Bruijn graphs and context-dependent arithmetic coding.

57 y learn nontrivial tasks requiring flexible (context-dependent) associations, memory maintenance, non

58 n by cortical interneurons therefore enables context-dependent behavior.

59 dulation of self-amplifying circuits directs context-dependent behavioral executions.

60 st contextual fear memories while preserving context-dependent behavioral flexibility.

61 physiological trait for enabling complex and context-dependent behaviors.

62 give rise to complex developmental programs, context-dependent behaviours and homeostatic activities.

63 -a kinesin-14 from Aspergillus nidulans-is a context-dependent bidirectional motor.

64 in late postnatal life to allow flexible and context-dependent brain control of somatosensation.

65 he nature of predation risk effects is often context dependent, but in some ecosystems these continge

66 Our findings reveal an additional example of context-dependent c-MET signaling diversity, required he

67 etwork of signaling circuits that coordinate context-dependent cell behavior.

68 ctivity, the spatial patterns of firing were context dependent: cells located caudally generally were

69 We found that oxytocin induced a context-dependent change in altruistic behavior away fro

70 Most significantly, this social context-dependent change in firing rate was evident even

71 We hypothesize that this social context-dependent change in frontal cortex activity is s

72 addition to offering a normative account of context-dependent changes in sensory responses, perceptu

73 s, highlighting recent findings of early and context-dependent choice-related activity in M2 during v

74 tor cortex OFF medication, compatible with a context-dependent compensatory role of the lateral premo

75 ulation of Bach2 expression, underlining the context-dependent complexity of NF-kappaB signalling in

76 Together, context-dependent conformational switches and biased dep

77 ctional importance of polyomaviral miRNAs is context dependent, consistent with an activity connected

78 invest optimally in immunity in the light of context-dependent constraints.

79 th the mPFC and amygdala and is recruited in context-dependent control of conditioned fear.

80 Adaptive memory requires context-dependent control over how information is retrie

81 This new theory, the context-dependent decay hypothesis, makes two key predic

82 l issues in previous work that supported the context-dependent decay hypothesis, we measured decay us

83 and expression of memories are critical for context-dependent decision making.

84 cuit is further demonstrated by performing a context-dependent decision-making task.

85 ate alphaKG-sensitive metabolic changes into context-dependent differentiation gene programs.

86 Mediator-associated kinases CDK8/19 are context-dependent drivers or suppressors of tumorigenesi

87 etDecoder will enable researchers to uncover context-dependent drug targets.

88 istic mutualisms with prokaryotes that solve context-dependent ecological problems.

89 ap between rare and complex diseases and the context-dependent effect of both rare and common alleles

90 l or life history trait that could explain a context-dependent effect of dioecy on diversification.

91 In this study, we identified a context-dependent effect of the nonsteroidal anti-inflam

92 Overall our data indicates that MTGR1 has a context-dependent effect on intestinal tumorigenesis.

93 These results highlight context-dependent effects of Notch activation during myo

94 Our study uncovers differential and context-dependent effects of SWI/SNF complex member loss

95 Our results reveal context-dependent effects of TGFbeta2 signaling in the s

96 vitro and in vivo assays suggested complex, context-dependent effects of the EDNRA variants on downs

97 tant mice suggest that LFNG protein may have context-dependent effects on Notch activity.

98 revealed that historical substitutions have context-dependent effects, indicating that possible adap

99 different cell types to investigate cellular context-dependent effects.

100 The consolidation of context-dependent emotional memory requires communicatio

101 TCF/LEF factors are ancient context-dependent enhancer-binding proteins that are act

102 ery rate (FDR) </= 0.05), 2,743 (12%) showed context-dependent eQTL effects.

103 ed individuals and systematically identified context-dependent eQTLs using a hypothesis-free strategy

104 ions suggest that economic choices reflect a context-dependent evaluation of attended options.

105 valuation of other options, making valuation context-dependent even when choices appear fully rationa

106 Our results highlight the rapid, context-dependent evolution of small RNA pathways and su

107 anging estimates, which may be the result of context-dependent expression of cell surface markers.

108 ligand of KIR3DS1 and have demonstrated cell-context-dependent expression of HLA-F that might explain

109 Proneural genes thus act in a context-dependent fashion as early determinants, promoti

110 nput from the brain serves to modify it in a context-dependent fashion.

111 123aIN/23aIN mice showed abnormally elevated context-dependent fear and a diminished ability to extin

112 d deficits in spatial learning and memory in context-dependent fear conditioning and in the Barnes ci

113 IFT20 in these cells significantly impaired context-dependent fear-related memory.

114 Egg-laying preference provided a context-dependent fitness benefit to larvae.

115 Immunity, however, is constrained by context-dependent fitness costs.

116 Moreover, we demonstrate that context-dependent fitness genes accurately recapitulate

117 To extend the catalog of human core and context-dependent fitness genes, we have developed a hig

118 etic experiment, we provide rare evidence of context-dependent fluctuating selection on growth rates

119 ow high annual variation in seed production, context-dependent foraging can have strong effects on na

120 either PL or BA exhibited similar degrees of context-dependent Fos expression; there were more Fos-po

121 cell-mediated immune responses, suggesting a context-dependent function of the PD-1/PD-L1 axis, and s

122 A2 (sPLA2s) as stem cell niche factors with context-dependent functions in the digestive tract.

123 ecification and provide new insight into the context-dependent functions of BRD4.

124 h gene expression and Hi-C data, we identify context-dependent functions of nucleosome-level states.

125 Further elucidation of the context-dependent functions of p38alpha signaling in tum

126 We suggest that CP110 has unique context-dependent functions, acting as both a suppressor

127 ed and unmethylated exons, highlighting gene context-dependent functions.

128 neurons are critical for a visually induced, context-dependent gamma rhythm in visual cortex.

129 putational model independently predicts that context-dependent gamma rhythms depend critically on SOM

130 of histone H4 at lysine 20 (H4K20me1), is a context-dependent GATA-1 corepressor in erythroid cells.

131 R in B. subtilis causes strand- and sequence-context-dependent GC --> AT transitions.

132 impact cancer cell metabolism, resulting in context-dependent gene essentiality.

133 With its distinct morphology, context-dependent growth, and experimental manipulabilit

134 r functional repertoire by forming different context-dependent higher-order complexes.

135 arginine mutations in antibody CDRs display context-dependent impacts on specificity and that affini

136 rganization and function of nucleoporins are context dependent in a way that is required for the stru

137 pheromones can be detected by many insects, context-dependent increased costs of high sensitivity mi

138 ity module also revealed that parasitism had context-dependent influences, for one prey species, with

139 code for researchers to explore genome-wide context-dependent information flow profiles and key gene

140 oder, a network biology platform that models context-dependent information flows using pairwise pheno

141 Plants use context-dependent information to calibrate growth respon

142 -of-words, which cannot capture semantic and context-dependent information well.

143 t (willful) muscle control with the aid of a context-dependent integration of somatosensory and visua

144 aradigms such as perceptual decision-making, context-dependent integration, multisensory integration,

145 LC neurons displayed context-dependent inter-relationships, with moderate, di

146 tform, COSPER, Litvin et al. (2015) identify context-dependent interactions between MEK and interfero

147 ic and -extrinsic mechanisms and relies upon context-dependent interactions with Notch ligand-express

148 ) transcriptional repressor characterized by context-dependent key roles in cell fate decision and tu

149 overlapping distributed systems involved in context-dependent learning and behavioral control.

150 Context-dependent locomotion responses were found in eac

151 at different OB output layers display unique context-dependent long-term ensemble plasticity, allowin

152 Ps as a basis for higher order function in a context dependent manner, allowing us to provide a detai

153 al alterations and gene activation in a cell context dependent manner.

154 a repressor or as an activator in a promoter-context dependent manner.

155 on of Ago2 occurs in a cell type- and tissue context-dependent manner and may correlate with its vari

156 that UBE3A regulates Wnt signaling in a cell context-dependent manner and that an autism-linked mutat

157 directly to in vivo tissue regeneration in a context-dependent manner and, unlike embryonic or plurip

158 also that these traits can be modulated in a context-dependent manner depending on the presence of co

159 GATA2- and AR-mediated gene expression in a context-dependent manner due to its reprogramming effect

160 te that disulfide bonds in proteins act in a context-dependent manner rather than simply as mechanica

161 We propose that IL-21 acts in a context-dependent manner to accentuate T cell subset dev

162 We propose these pathways act in a context-dependent manner to drive phenotypic changes tha

163 rts its chaperone or enzymatic function in a context-dependent manner to maintain neuronal health.

164 gulated in multiple tumor types (albeit in a context-dependent manner), and this has stimulated the d

165 ective of stimulus features in a supramodal, context-dependent manner, and additionally reflects the

166 ppressor or, conversely, as an oncogene in a context-dependent manner, and it also controls many phys

167 ), promotes exon inclusion or exclusion in a context-dependent manner, and stabilizes mRNA when assoc

168 echanism to respond to multiple stimuli in a context-dependent manner, enabling tissue regeneration i

169 lements and transcript abundance of genes in context-dependent manner, reinforcing the role of DNA me

170 epression domain inhibits transcription in a context-dependent manner, the N-terminal repression doma

171 e particular behavior among many others in a context-dependent manner, yet the mechanisms underlying

172 sculpted to guide behavioral decisions in a context-dependent manner.

173 main to regulate beta-catenin signaling in a context-dependent manner.

174 ion of multiple cell signaling pathways in a context-dependent manner.

175 expression of hundreds of genes in a tissue context-dependent manner.

176 ting a variant's regulatory probability in a context-dependent manner.

177 nuclei where it modulates transcription in a context-dependent manner.

178 its role from anti- to pro-tumorigenic in a context-dependent manner.

179 cell differentiation and proliferation in a context-dependent manner.

180 tory cytokines affect the immune system in a context-dependent manner.

181 ns of PER as repressor and de-repressor in a context-dependent manner.

182 nchorage-independent growth, again in a cell context-dependent manner.

183 mechanisms to drive oncogenic processes in a context-dependent manner.

184 ly among the five AAP2BRs and functions in a context-dependent manner.

185 est that NL proteins regulate chromatin in a context-dependent manner.

186 including G9a/GLP and Suv39H1 in a chromatin context-dependent manner.

187 e or causative with regard to pathology in a context-dependent manner.

188 es can also produce 'female-like' duets in a context-dependent manner.

189 f callosal and subcerebral neurons in a cell context-dependent manner.

190 s and population dynamics, but doing so in a context-dependent manner.

191 the adaptive potential of such effects in a context-dependent manner.

192 pport or inhibit inflammatory processes in a context-dependent manner.

193 d tumour-suppressor gene that functions in a context-dependent manner.

194 rease translational accuracy in a stop codon context-dependent manner.

195 action with Wnt ligands and antagonists in a context-dependent manner.

196 regulated they can also be maladaptive in a context-dependent manner.

197 decreased during cell-to-cell infection in a context-dependent manner.

198 s to be selectively modulated in a task- and context-dependent manner.

199 Self-other mergence operated in a context-dependent manner: interacting with high or low p

200 In this study, we identified a context-dependent mechanism of escape whereby tumor cell

201 Context-dependent mechanisms are crucial for transcripti

202 It is an open question whether such context-dependent memory effects can be captured by the

203 To address the circuit mechanisms underlying context-dependent memory function, we determined through

204 ng a critical period for promotion of social-context-dependent memory.

205 eurons are likely the integration center for context-dependent micturition behavior.

206 gate the neural architecture underlying such context-dependent modifications, we studied Bengalese fi

207 view that inhibitory neuron subtypes perform context-dependent modulation of excitatory activity, as

208 ferent cellular components, thereby allowing context-dependent modulation of function.IMPORTANCE A th

209 Our study unveils a context-dependent modulation of the TRPA1-V1 complex, an

210 nics/molecular mechanics to analyze sequence context-dependent mutagenesis at mononucleotide repeats

211 ready GC-poor regions, and using our precise context-dependent mutation rates to predict long-term ev

212 The framework explores DNA context-dependent mutational patterns and underlying som

213 ose several tools for the analysis of cancer context-dependent mutations, which are implemented in an

214 al techniques have shed light on nuanced and context-dependent nano-bio interactions within cells.

215 However, the highly context-dependent nature of protection mutualisms makes

216 nding the processes that underpin the highly context-dependent nature of WNT/beta-catenin signaling i

217 r changes after anti-VEGF therapy can have a context-dependent negative impact on overall therapeutic

218 n the lack of computational tools to dissect context-dependent networks and gene activities, we devel

219 bal brain activity mode that is regulated by context-dependent neuromodulators and acts as a major dr

220 Interestingly, our findings implicate the context-dependent, neuronal milieu as a key factor in au

221 Collectively, our results reveal possibly a context-dependent, non-classical regulatory role for SOX

222 is issue of Cancer Cell, Sun et al. describe context-dependent oncogenic and tumor-suppressive functi

223 Thus, we identify context-dependent oncogenic driver events that may guide

224 re maintained by balancing selection through context-dependent or fluctuating selection.

225 These results elucidate neural mechanisms of context-dependent pain modulation and their relation to

226 ponses emerged 30 hr after injury, involving context-dependent patterning and stem-cell-specializatio

227 ts were associated with different, therefore context-dependent, patterns of neural variability induce

228 nesis is dose and context dependent, and the context-dependent phenotypes are associated with differe

229 this master regulator mediates distinct cell context-dependent phenotypes.

230 Importantly, PRC2 inactivation results in context-dependent phenotypic alterations, with implicati

231 The CSSs examine context-dependent phenotypic effects independently among

232 Despite having many context-dependent physiological roles and being implicat

233 Vocal learning and social context-dependent plasticity in songbirds depend on a ba

234 are often completely unstructured and highly context dependent, posing essentially a machine-learning

235 IL-6 has context-dependent pro- and anti-inflammatory properties

236 le, and provide the first example of another context-dependent process, habitat compression, function

237 beetles are determined by patch quality and context-dependent processes at multiple spatial scales.

238 strictly on action history, or also reflect context-dependent processes related to predictive motor

239 use-dependent, and dynamically-evolving and context-dependent processes that reflect prediction of f

240 re we experimentally confirm the role of one context-dependent processes, spatial contagion, function

241 Up to 9 of the 10 defined modes coexisted in context-dependent proportions.

242 This demonstration of context-dependent protease cleavage has implications for

243 IL-22 is a dual natured cytokine which has context-dependent protective and pathogenic properties d

244 tly been linked to cancer cell motility as a context-dependent regulator of multiple pathways, its ro

245 the transcriptional landscape to identify a context-dependent regulatory pathway controlling APA in

246 TRAF3 plays a variety of context-dependent regulatory roles in all types of immun

247 These findings are better explained in a context-dependent reinforcement learning model.

248 The context-dependent reinstatement of assembly patterns who

249 This context-dependent relationship may be mediated by increa

250 d the hypothesis that the PL is important in context-dependent responding learned during conditioning

251 In the MCF7 cell models a context-dependent response is observed with paclitaxel t

252 mor structure, while cisplatin showed a more context-dependent response.

253 ifferent activation states, which may permit context-dependent responses to infection.

254 ons in the central amygdala is necessary for context-dependent retrieval of cued fear memories.

255 Taken together, our work shows context-dependent rewiring of transcription factor bindi

256 Overall, our results highlight a context-dependent role for ARF in modulating the drug re

257 Overall, this study reveals a context-dependent role for IL-21 in sustaining effector

258 esults demonstrate a surprising temporal and context-dependent role for neutrophils in restraining au

259 eal that the Notch signaling pathway plays a context-dependent role for optimal cytokine production b

260 pport a previously unrecognized genetic cell context-dependent role for ZEB1 and suggest that NOTCH1

261 s often overexpressed, suggesting a possible context-dependent role in growth promotion.

262 phy, suggesting that this phenomenon plays a context-dependent role in vivo.

263 her, our results demonstrate the nuanced and context-dependent role of DNA methylation in the functio

264 the present study, we aimed to elucidate the context-dependent role of Elf5 at the interface between

265 Thus, our findings demonstrate context-dependent roles for EGFR-modulated class I PI3K/

266 In summary, our study demonstrates the context-dependent roles of Brg1 and points to potential

267 Consistent with the context-dependent roles of EBNA3B and EBNA3C as activato

268 or cell fate determination, resulting in the context-dependent roles of key transcription factors dur

269 ther work is warranted to define the in vivo context-dependent roles of these proteins and determine

270 hers (mec-7 and mec-12) perform specialized, context-dependent roles.

271 sentations and adjudicating among competing, context-dependent rules.

272 parts of the mesolimbic system, in tracking context-dependent salience of old and new information.

273 , that learning option values in a relative--context-dependent--scale offers a simple computational s

274 uency of different vocal gestures, whereas a context-dependent scheme would require the brain to calc

275 To quantify the importance of phenotype- and context-dependent selection on mating success, we repeat

276 in alphavbeta3 within the BM niche acts as a context-dependent signal modulator to regulate the HSC f

277 Thus multiple context-dependent signals drive VE-cadherin endocytosis,

278 responses to infection and damage, relaying context-dependent signals that determine inflammatory ce

279 f the VMH (VMHdm/c), and observed a range of context-dependent somatomotor and autonomic responses re

280 d network level representations that support context-dependent spatial maps.

281 l synapses with similar overall functions or context-dependent specifiers of synapse properties.

282 Thus, neurexins function primarily as context-dependent specifiers of synapses.

283 human fMRI and monkey electrophysiology in a context-dependent stop signal task, we found a functiona

284 t globally reduced translation may provide a context-dependent survival advantage that must be consid

285 of autophagy in cancer has been shown to be context-dependent, the role of autophagy in tumor cell s

286 Although context dependent, these native ecosystems subjected to

287 n inflammation and sepsis, whereas ANG2 is a context-dependent Tie2 agonist or antagonist.

288 Wnt/beta-catenin signaling elicits context-dependent transcription switches that determine

289 In summary, ARID1A has context-dependent tumor-suppressive and oncogenic roles

290 Here, we investigate the neurobiology of context-dependent valuation in 22 human subjects using f

291 Such context-dependent valuations may lead to biased decision

292 differed between plasmids and were strongly context dependent, varying with medium, plasmid status o

293 t appraisal and racially biased behaviour in context-dependent ways.

294 d adult, and the impact of oncogenes is cell-context dependent, we hypothesized that the childhood af

295 -herbivore interaction outcomes are famously context-dependent, we demonstrated that herbivores suppr

296 Host fitness was strongly context dependent: whereas hosts benefited from symbiosi

297 ovide new insights into both the general and context-dependent wiring of transcription factor network

298 p/TiPARP) by AhR ligands were gene- and cell context-dependent with the Caco-2 cells being the most r

299 The effects of IL-4/ll-13 may be context dependent, with differing roles in homeostasis a

300 eservoirs on the river water temperature was context-dependent, with the heating effect (and the impa