ライフサイエンスコーパス: contiguous

1 ae solely consists of trisaccharide units of contiguous (1 --> 4)-beta-linked glucose residues joined

2 omous underwater vehicle Sentry to conduct a contiguous, 12.5 km photoimaging survey of sea-floor col

3 infected tissue homogenates, we assembled a contiguous 174-kb genome sequence containing 128 unique

4 Epithelial cells often form a contiguous 2-dimensional sheet that is held together by

5 ame instruments were readministered at eight contiguous 2-year time periods.

6 change for the period 9000 bp to present, in contiguous 200 year time intervals.

7 t plant communities at meter scales across a contiguous 25,000 m(2) archaeological land surface at Ol

8 Names were spliced into contiguous 3-letter substrings, and these were used as t

9 nfluences aortic morphologic findings of the contiguous abdominal aorta.

10 application of 100 pulses) did not result in contiguous ablation.

11 were generated by interpolating data between contiguous acquisition steps, corrected for radiotracer

12 ge-scale cooperation is required to maintain contiguous air contact across the posterior breathing sp

13 rpenoids are the only biomolecule class with contiguous, alicyclic carbon backbones of this size.

14 an IDP in isolation but will form a single, contiguous alpha-helix upon binding the folded protein M

15 fibrosis spreads from affected alveoli into contiguous alveoli and leads to death by asphyxiation.

16 fibrosis spreads from affected alveoli into contiguous alveoli, creating a reticular network that le

17 ough a critical contact region requiring two contiguous amino acid residues, Arg(286) and Leu(287).

18 We identified two contiguous amino acids, valine-381 and serine-382, locat

19 ot through a mechanically connected array of contiguous amino acids.

20 structed into short stretches of overlapping contiguous amino acids.

21 of reconstruction, counted as the number of contiguous ancestral regions found, decreases rapidly wi

22 nd produce a de novo assembly that is highly contiguous and accurate: The contig N50 length is more t

23 LCON-based assemblies are substantially more contiguous and complete than alternate short- or long-re

24 Regions of differential expression were contiguous and showed similar morphological phenotype in

25 as those changes are likely to be greater in contiguous and unfragmented habitats.

26 g-read sequencing data into highly accurate, contiguous, and correctly phased diploid genomes.

27 ATWI was defined as T-wave inversion in >/=2 contiguous anterior leads (V1 to V4).

28 e assemblies that are accurate, complete and contiguous are essential for identifying important struc

29 fic NMR line-broadening effects mapping to a contiguous area on the surface of the protein.

30 tory computational model is developed of the contiguous areas of retinal capillary loss which play a

31 usion cannot explain the occurrence of large contiguous areas of retinal ischemia.

32 sures for white elm populations in Spain and contiguous areas of southern France.

33 ry best practices for obtaining accurate and contiguous assemblies, a 'missing manual' that guides ke

34 h next-generation mapping generated a highly contiguous assembly, with a contig N50 size of 17.9 Mb a

35 , where the relative stereochemistry at five contiguous asymmetric centers can be controlled through

36 single diastereoisomers that incorporate two contiguous asymmetric centers, one tertiary and one an a

37 ed sample capture and hybridization to large contiguous BAC baits reduces sample and probe hybridizat

38 th alternating barbs and a uniform series of contiguous barbules, supporting the developmental hypoth

39 uggesting that an initial homology test of 8 contiguous bases rejects most interactions containing mo

40 Contiguous brain regions associated with a given behavio

41 d are guided by contact with the wall to the contiguous branch channel independent of its width.

42 The goals are to build a contiguous bridge from basic science, accelerate the adv

43 es specificity based on the use of spatially contiguous but distinct domains.

44 cnvCapSeq was benchmarked using a simulated contiguous capture sequencing dataset comprising 21 geno

45 and C20 families depending on the number of contiguous carbon atoms that constitute their central fr

46 icyclic tropane skeletons, allowing for five contiguous carbon stereocenters to be set in a single ex

47 fferentiates as a unique population within a contiguous cartilage element.

48 ts the first solved crystal structure of two contiguous CBM22 modules.

49 opy, and immunolabeling, we demonstrate that contiguous cell walls indeed exhibit hybrid mechanochemi

50 -biting, generalist tick were collected from contiguous chaparral and grassland habitats, and RNA fro

51 y, it turns out that achieving a system with contiguous columns is detrimental to the solar cell effi

52 an method to partition PKA into structurally contiguous "communities." Most of these communities incl

53 e projects have a dual purpose: delivering a contiguous, complete genome assembly and creating a full

54 Mutations of the contiguous conserved amino acids Pro-148 and Leu-149 in

55 s of similarly aged youth occurred, from non-contiguous counties within the same state as the cluster

56 atial patterns of measles vaccination in ten contiguous countries in the African Great Lakes region b

57 ion between the North China Craton (NCC) and contiguous cratons is important for the configuration of

58 data, we propose a structural model in which contiguous CsPABPN1 RRM monomers wrap around the RNA mol

59 pray pulsation is controlled by specialized, contiguous cuticular structures located at the junction

60 blish that RWA is distinct from the caudally contiguous CWA, we determined sources of thalamic inputs

61 This work presents the most contiguous diploid human genome assembly so far, with ex

62 bed de novo goat genome sequence is the most contiguous diploid vertebrate assembly generated thus fa

63 Anatomically, contiguous disease spread on MRI was not apparent in thi

64 Both interactions are directed by a contiguous DNA- and histone-binding domain (DHBD) harbor

65 osition connects these chitin buds to form a contiguous duct that largely separates from the apical s

66 ls, the primary cilium insulates itself from contiguous dynamic membrane processes on the cell surfac

67 -controlled microfluidic switchboard allowed contiguous electrochemical measurements of glucose and l

68 Hrr25 central domain and Mam1 form a novel, contiguous embellishment to the Hrr25 kinase domain that

69 lar linear ablation catheter safely delivers contiguous endocardial or epicardial lesions without gap

70 that the ABCDE sites are located in the only contiguous extended region of this huge protein that is

71 invasion into the pelvicalyceal system with contiguous extension up to the urinary bladder.

72 hepatic veins (V) or portal bifurcation (P), contiguous extrahepatic tumour (E), multifocal tumour (F

73 hree new carbon nitrogen bonds are formed in contiguous fashion, involves in situ generation of enami

74 bonds and one ring in a single operation in contiguous fashion.

75 ould create >251,000 ha in total of restored contiguous forest and enhance species persistence by a f

76 Russian forests are the largest contiguous forest belt in the world that accounts for 17

77 st fragments, especially within biomes where contiguous forest cover has diminished dramatically, but

78 ould create >316,000 ha in total of restored contiguous forest.

79 In particular, those possessing numerous contiguous, fully substituted carbon atoms (i.e., tertia

80 bolic pathways that produce SMs are found in contiguous gene clusters in fungal genomes, an atypical

81 uals have been identified with OTCD due to a contiguous gene deletion at Xp11.4-p21.1 and unique clin

82 We propose that the contiguous gene deletion could contribute to the severit

83 are hemizygous in Jacobsen syndrome, an 11q contiguous gene deletion disorder involving thrombocytop

84 retardation) is a rare syndrome caused by a contiguous gene deletion in the 11p13-14 region.

85 DiGeorge syndrome) is the most common known contiguous gene deletion syndrome and is associated with

86 UBE3A) gene, while PWS is still considered a contiguous gene disorder.

87 predominant mechanism underlying PMP22-RAI1 contiguous gene duplications and provides further eviden

88 e severe renal manifestations of the TSC/PKD contiguous gene syndrome and open new perspectives for t

89 containing a targeted deletion of a group of contiguous genes (for a total of 2,069 genes deleted) wa

90 ns in C1R (15 families) or C1S (2 families), contiguous genes in the mapped locus that encode subunit

91 rvoir of biosynthetic gene clusters, sets of contiguous genes that have the potential to produce drug

92 Four contiguous genes were duplicated along with vig2, but th

93 experiment, we show that transcripts from 22 contiguous genes, including those encoding IsoMO, were h

94 e large aberrations that can affect multiple contiguous genes, no possible therapeutic strategies for

95 nable the coordinate expression of groups of contiguous genes.

96 own to regulate genes over long distances, a contiguous genome assembly is crucial for predicting and

97 Accurate and contiguous genome assembly is key to a comprehensive und

98 Firstly, the analysis of contiguous genome segments across species, has highlight

99 The LCRs flanking a contiguous genomic interval encompassing both RAI1 and P

100 Both conservation of contiguous gp41 membrane-proximal external region (MPER)

101 er scaffold P4HB compared with a consecutive contiguous group treated with porcine cadaveric mesh for

102 g adenomas and PanINs, contrasting with more contiguous growth of advanced subclones.

103 uence containing five runs of at least three contiguous guanines separated by one or more bases, conf

104 to climate change than communities found in contiguous habitats because they are comprised of specie

105 erived from XBP1 pre-mRNA, that folds as two contiguous hairpins.

106 , assemble into antimicrobial pores and form contiguous helices that are biologically promiscuous and

107 f any of these factors produces the multiple contiguous heterocyst (Mch) phenotype.

108 ssing strain produced an increased number of contiguous heterocysts but a decreased percentage of tot

109 s and increased implicit times in at least 5 contiguous hexagons after surgery on all 3 examinations

110 its of public health importance by observing contiguous homozygous segments (runs of homozygosity), w

111 evealed that teams commonly missed swaths of contiguous households and indicated that geospatial data

112 de deletion polymorphisms involving multiple contiguous IGHD genes.

113 The disordered regions are not contiguous in sequence to the site of mutation, and even

114 es spatially adjacent fragments that are not contiguous in sequence-a major bottleneck in structure p

115 l similarity of CblD to CblC, believed to be contiguous in the cobalamin trafficking pathway, suggest

116 s infarct, and microinfarct with preexisting contiguous infarct can be differentiated on the basis of

117 nique for assessing MECV in acute patchy and contiguous infarct caused by obstruction of major and mi

118 mm(3) (120 000 count) microemboli (group 3), contiguous infarct with left anterior descending artery

119 Patchy microinfarct, contiguous infarct, and microinfarct with preexisting co

120 thyl chemical shift changes in I-Mad2 form a contiguous, interior network that connects its C-Mad2-bi

121 ontinuously synthesized DNA fragments into a contiguous lagging strand.

122 criteria of 0.1 mV or greater in at least 2 contiguous leads.

123 ing radiculopathy or myeloradiculopathy at 2 contiguous levels from C3-C7 that was unresponsive to co

124 Despite contiguous location in the genome and shared polyadenyla

125 etions ranging from 350 bp to 6900 bp in non-contiguous loci on several chromosomes, most commonly in

126 phospholipid through the basic helix 3 and a contiguous loop with moderate affinity.

127 s ductal growth, leads to the formation of a contiguous lumen, and facilitates lumen expansion throug

128 ng using continuously driven domain walls in contiguous magnetic tracks is lacking.

129 ked and eventually fusing to form the single contiguous MAT locus that is now extant in the pathogeni

130 rately assessing structural variation across contiguous megabase DNA regions.

131 enables us to perform targeted isolation of contiguous megabase-sized segments of the genome.

132 ic reticulum (ER) are components of the same contiguous membrane system and yet have distinct cellula

133 ome but not all ERC vesicles are tethered by contiguous "membrane bridges." Furthermore, tubular recy

134 Connected cells have contiguous membranes, and the core infectious viral mach

135 Connected cells appeared to have contiguous membranes, and the core infectious viral mach

136 e observed connecting two distant cells with contiguous membranes, with the core infectious viral mac

137 modeling and nanoindentations in silico of a contiguous microtubule fragment.

138 Notably, in 5 contiguous Midwest states, nearly half of young women wi

139 the protein aligned parallel to the RNA and contiguous motifs aligned with contiguous nucleotides su

140 orm for sensing systems for the detection of contiguous multi-sites of DNA methylation without extern

141 tion on the level of methylation at specific contiguous multi-sites, not to mention easy-to-use detec

142 ure multicellular host tissues into a single contiguous multinucleate cell.

143 The frequency of contiguous mutations was analyzed using a novel computat

144 e the kinetics of neurofilament transport in contiguous myelinated and unmyelinated segments of axons

145 F(65) inter-domain residues in recognizing a contiguous, nine-nucleotide Py tract.

146 f bromodomains, and only in conjunction with contiguous nucleosomes.

147 o the RNA and contiguous motifs aligned with contiguous nucleotides such that the final PPR motif ali

148 anglion cells (RGCs) in response to a large, contiguous object, but not to disjointed objects.

149 the chromosome typically as a divergent but contiguous operon.

150 Generating a contiguous, ordered reference sequence of a complex geno

151 nventional approaches using the full-length, contiguous ORF2p make it difficult to study the involvem

152 s for large multifocal tumors or tumors with contiguous organ involvement remain to be defined.

153 mes for large multifocal ICCs or tumors with contiguous organ involvement.

154 SD were R2 resection, resection of 3 or more contiguous organs, and histologic type.

155 An immunotherapy formulation consisting of 3 contiguous overlapping peptides (COPs) derived from Bet

156 igation of the architectural (i.e. bulge vs. contiguous pairs) and sequence (Watson-Crick vs. G:U pai

157 ng UV and blue cones typically converge into contiguous pairs, despite the regular spacing of their c

158 Since the function of a short contiguous peptide minimotif can be introduced or elimin

159 s they facilitate the construction of highly contiguous physical genome maps obviating the need for l

160 other approaches now aim to sequence longer contiguous pieces of DNA, which are essential for resolv

161 regression (PLR) criteria as follows: any 2 contiguous points in the same hemifield progressing (</=

162 lamina, the intermediate nidopallium; and a contiguous portion of the ventral mesopallium, the mesop

163 r LA endocardial voltage and infiltration of contiguous posterior LA muscle by epicardial fat, repres

164 (which would additionally require culling of contiguous premises).

165 gioselectively the hydrogen at C5(II) of the contiguous pyranose.

166 ce coil MRI scans were obtained in multiple, contiguous, quasicoronal planes during monocular central

167 ned and highly substituted cyclobutenes with contiguous quaternary carbon centers can be synthesized

168 ts feature multiple stereocenters, including contiguous quaternary carbons.

169 ot leading to carbon chains bearing multiple contiguous quaternary stereogenic centers.

170 x II of the DnaJ J-domain and a structurally contiguous region of DnaK, involving lobe IIA of the nuc

171 om 188 patients enabled us to assemble 7,190 contiguous regions (contigs) larger than 1 kbp, of which

172 ing over 54 kb of genomic DNA from three non-contiguous regions in a single recombination event.

173 allows the discovery of methylation 'loci'; contiguous regions of methylation consistently methylate

174 -domain monomers that dimerize, revealed few contiguous regions of similar exposed residues, renderin

175 d region (DER) finder that seeks to identify contiguous regions of the genome showing differential ex

176 t localization of the Scm-SAM domain in long contiguous regions on polytene chromosomes revealed its

177 Slitlamp examination revealed a contiguous ring of pigmented translucent iris cysts at t

178 omplexes, effectively reducing the available contiguous RNA-binding surfaces.

179 These R-lesions could be R-tracts, contiguous runs of >/=4 RNA nucleotides within DNA stran

180 Strands of DNA with four or more contiguous runs of 2'-deoxycytidine (dC) nucleotides hav

181 nct layers owing to the immiscibility of the contiguous salt and metal phases.

182 nthesis and testing of peptides derived from contiguous segments of lysozyme's primary amino acid seq

183 SNP-based LD block was not always physically contiguous-segments of uncorrelated methylation as long

184 Molecules composed of a contiguous sequence of double bonds, the [n]cumulenes, s

185 ality draft genomes, containing 150 or fewer contiguous sequences, from disease isolate collections:

186 This resulted in four contiguous sequences: two large circular chromosomes and

187 e RbCuTe material but in structures having a contiguous set of 3D chemical bonds spanning the entire

188 Twelve contiguous short-axis sections and six four-chamber sect

189 xanes consisting of a polyyne, with up to 24 contiguous sp-hybridized carbon atoms, threaded through

190 eaction leading to peptides bearing multiple contiguous staples connected by a central spiro ring jun

191 , West Nile virus (WNV) has spread to all 48 contiguous states in the United States and is now the le

192 eriod from 2010 to 2012 were over 42% in the contiguous states of Nebraska, Missouri, Colorado, Iowa,

193 , West Nile virus (WNV) has spread to all 48 contiguous states of the United States and is now the le

194 ffective to secure the F-ring and the fourth contiguous stereocenter of (-)-deoxoapodine with complet

195 ng tricyclic scaffolds containing up to five contiguous stereocenters (including quaternary stereocen

196 nitrogen heterocycles possessing up to three contiguous stereocenters and seven fused cycles.

197 of an amino allyl boronic ester bearing four contiguous stereocenters as a single diastereomer.

198 nalized perhydroquinoline core displays four contiguous stereocenters including an all-carbon quatern

199 d stereoselectively forming three of the ten contiguous stereocenters of chromodorolide B.

200 ex tetracyclic architectures containing five contiguous stereocenters with excellent diastereocontrol

201 reactions, was applied to install the three contiguous stereocenters with high enantio- and diastere

202 ured hydroxyisochromanone core bearing three contiguous stereocenters, a modular oxazole formation, a

203 olecular scaffolds which contain up to seven contiguous stereocenters.

204 fully substituted glycolic esters with three contiguous stereocenters.

205 of hydroxyl-isochromanones with up to three contiguous stereocenters.

206 n-ketols and acyclic compounds with multiple contiguous stereocenters.

207 to as "anhydronium bases") containing three contiguous stereocenters.

208 ers, forming gamma-butyrolactones with three contiguous stereocenters.

209 gamma- and delta-lactones bearing up to four contiguous stereocenters.

210 a ketone, to give products containing three contiguous stereocenters.

211 hly enantiomerically enriched amines bearing contiguous stereocenters.

212 eading to branched products with up to three contiguous stereocentres in a (syn, anti)-mode with exce

213 ers of an organic compound that has multiple contiguous stereocentres remains a challenge.

214 -alcohol products, which contain up to three contiguous stereocentres.

215 y active complex natural products containing contiguous stereogenic carbon centres.

216 tide with a carbon backbone containing eight contiguous stereogenic carbons in a C20 hexacyclic core.

217 Products contain two contiguous stereogenic centers and are obtained in up to

218 cyclic iridium complex to form products with contiguous stereogenic centers derived from the nucleoph

219 e 4,5-dihydro-1H-benzo[c]azepines with three contiguous stereogenic centers have been assembled by co

220 ruction of tricyclic architectures with four contiguous stereogenic centers in a single step.

221 e beta-hydroxyboronates containing up to two contiguous stereogenic centers in up to 99:1 e.r. and gr

222 Polycyclic amines containing three contiguous stereogenic centers were obtained with excell

223 The products contain three new contiguous stereogenic centers, generated with a high le

224 functionalized core, possessing a series of contiguous stereogenic centers.

225 mation of dihydropyran frameworks with three contiguous stereogenic centers.

226 cted natural products containing two or more contiguous stereogenic quaternary carbon atoms and key r

227 ex natural products that contain two or more contiguous stereogenic quaternary carbon atoms in their

228 ular units that combine to form a functional contiguous structure; in muscle-less limbs, tendons deve

229 nsmural lesions without collateral injury to contiguous structures.

230 en balanced by treatment group in a selected contiguous study area were re-enrolled and 1613 (89%) pr

231 ral models reveal that these residues form a contiguous surface within a monomer and, interestingly,

232 determined using a segmentation technique on contiguous T1-weighted axial MRI slices from the level o

233 gorithms have been specifically designed for contiguous target sequencing, despite its increasing imp

234 oblem of segment detection, which identifies contiguous time periods with consistent network structur

235 h simultaneously partitions the network into contiguous time segments with consistent community organ

236 unpaired regions that are adjacent, but not contiguous to segments cleaved by RNase E.

237 dreds to thousands of short tracks into long contiguous trails.

238 For stimulus patterns with contiguous transitions and with nonadjacent elements, si

239 proximal stalk region as well as that of its contiguous transmembrane and cytoplasmic domain, inclusi

240 nerate substituted isocyanides incorporating contiguous tri- and tetra-substituted centers.

241 PNG) lies within one of the largest areas of contiguous tropical forest and is characterized by envir

242 well suited to acquire membrane patches from contiguous tumor cells by a cell-to-cell contact-depende

243 ia concentrations in large reservoirs in the contiguous U.S.

244 p surface air HCHO concentrations across the contiguous U.S.

245 osure data with CLRD mortality for all 3,109 contiguous U.S. counties.

246 annual average NO2 measurements (1990-2012, contiguous U.S. EPA sites).

247 ciated with kidney transplantation in the 48 contiguous U.S. states.

248 nd seasonal isoscape was constructed for the contiguous U.S., which demonstrates seasonal and regiona

249 l cloud-to-ground lightning flashes over the contiguous United States (CONUS).

250 ality rates (CDC WONDER) for counties in the contiguous United States (n = 3,109) were investigated u

251 stimates of fresh (land-derived) SGD for the contiguous United States based on historical climate rec

252 The contiguous United States contains a disconnected patchwo

253 0y), and on life expectancy at birth, in the contiguous United States during 1980-2010.

254 In 2012, the contiguous United States experienced exceptionally warm

255 distribution of projected population of the contiguous United States for 2030 and 2050, depicting on

256 uring the past decade (2001-2010) across the contiguous United States have been observed to start 3.0

257 (region, state, county, urban area) for the contiguous United States in 2000 and 2010.

258 f poverty across geographical regions in the contiguous United States is associated with kidney trans

259 s one of the few continental glaciers in the contiguous United States known to preserve environmental

260 Here we project land-use change in the contiguous United States to 2051 under two plausible bas

261 ur approach to all U.S. Census blocks in the contiguous United States to provide 132 months of public

262 urrence of subsequent precipitation over the contiguous United States using remotely sensed soil mois

263 4 wastewater treatment plants (WWTPs) in the contiguous United States was investigated.

264 n environmental quality and mortality in the contiguous United States, 2000-2005.

265 on terrestrial and aquatic ecosystems in the contiguous United States, an area that includes 20 shale

266 occur first in eastern Beringia, next in the contiguous United States, and last in South America.

267 rconnected power control areas (PCAs) in the contiguous United States, Canada, and Northern Mexico.

268 Across the contiguous United States, cities' hard infrastructures h

269 For the contiguous United States, extinction began at ca. 12,900

270 analyzing fragmentation patterns across the contiguous United States, we demonstrate that only 41% o

271 abase of individual rain events spanning the contiguous United States.

272 t PM2.5 during pregnancy and term LBW in the contiguous United States.

273 e of smoke on ozone (O3) abundances over the contiguous United States.

274 ydrologic/water quality network model of the contiguous United States.

275 and precipitation at higher latitudes in the contiguous United States.

276 an increased rate of death from CLRD in the contiguous United States.

277 sions for cattle, swine, and poultry for the contiguous United States.

278 rvey of students in secondary schools in the contiguous United States.

279 HATS comprised Medicare beneficiaries in the contiguous United States.

280 ivity - to human land development across the contiguous United States.

281 o climate change at the state level over the Contiguous United States.

282 nomic inequalities in noise pollution in the contiguous United States; and b) consider the modifying

283 d had a larger cross-sectional area than the contiguous unmyelinated segments, and this correlated wi

284 se clustering, explaining the preference for contiguous uridine tracts.

285 mass and soil, equivalent to >8% of the C in contiguous US forests.

286 Our assessments over contiguous US suggest consistent increase in water stres

287 tion median HDD + CDD will be reduced in the contiguous US, decreasing in the North and increasing in

288 opposite chirality are incapable of forming contiguous Watson-Crick base pairs with each other-has e

289 e survey provided >31000 images and revealed contiguous, white-colored bacterial colonization coating

290 best pooled data assembly produced a highly contiguous wild-type C. elegans genome containing 48 con

291 Endocardial flowers are contiguous with coronary vessels and associated with sub

292 ent of the inner enamel organic matrix layer contiguous with the DEJ.

293 chorioretinal atrophy of the posterior pole contiguous with the disc in all but 1 patient that was a

294 ) to a conserved cAMP response element (CRE) contiguous with the NFAT binding site in the FGF-23 prom

295 y articulated to the thorax but also broadly contiguous with the notum anteriorly and posteriorly (de

296 At the internal border, the material was contiguous with the outer portion of the RPE band.

297 The vast majority of endothelial cells were contiguous with the parent artery and had smooth muscle

298 n humans overlap the RAD50 gene and thus are contiguous with the previously described TH2 locus contr

299 At 4 and 8 weeks, all samples contiguous with the tissue along the parent arteries had

300 four-electrode arrays, IRE can create large contiguous zones of treatment effect in clinically accep