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1 ing B cell populations could allow the virus continual access to the B cell lineage and, subsequent t
2 ice sheets, where the exceptional purity and continual accumulation of ice permit analyses not possib
5 to acute hypoxia in the vasculature, but its continual activation by chronic hypoxia can accentuate v
6 equencies, indicative of the long periods of continual activation necessary to acquire the BNAb pheno
11 es and suggests that these viruses are under continual adaptation due to changes in their environment
14 ly viewed as an important process during the continual adaptation of microbes to changing environment
17 ns of these networks are the products of the continual addition of newly discovered genetic, molecula
19 lly persist, and the physician needs to make continual adjustments in medications to minimize these p
21 xytocin trial, we confirmed that the current continual administration also significantly mitigated be
22 ring the last couple of years there has been continual advancement in our understanding of how to ana
23 Increasing interest has been accompanied by continual advances in energy delivery, application techn
25 rm goal of maize (Zea mays) breeding to meet continual and increasing food demands worldwide, but the
30 lows refinement of the database over time by continual application of random hash functions, with the
31 ion, institution of appropriate therapy, and continual assessment for children with sepsis and shock
35 o protect the integrity of the genome from a continual barrage of potentially detrimental insults.
36 e selumetinib, 75 mg orally twice daily on a continual basis (n = 50), or chemotherapy (temozolomide,
37 current antibiotics, we find ourselves in a continual battle to identify new antibacterial agents an
38 e a concept of contiguous immunity, in which continual bidirectional cross-talk between innate and ad
39 nd angle, resulting in high compressibility, continual breakup of tetrahedral connectivity and viscos
40 , resulting in subcellular domains of nearly continual Ca2+ influx called 'persistent Ca2+ sparklets'
41 g pathways are regulated under conditions of continual Ca2+ transients that mediate cardiac contracti
45 ggest that the healthy adult brain undergoes continual change driven by development and repair proces
46 immune escape: ongoing evolution allows the continual circulation of seasonal influenza, while novel
47 g these putative roles has been pursued with continual comparisons of human RNase 1 to bovine RNase A
48 our visual spatial attention depends upon a continual competition between internally generated goals
49 ral and functional integrity during years of continual contraction, but the extent to which new cell
50 es in prolonging disease progression through continual control of SIV subpopulations from various ana
53 XOPS-mCFP transgenic zebrafish experience a continual cycle of rod photoreceptor development and deg
58 F in which there was no recovery phase and a continual decline in monthly bleeding to approximately 1
61 n the San Francisco Estuary, a population in continual decline since its initial collapse during the
62 on shifted toward more ancient elements with continual declining rates in recent Alu activity along t
64 focuses on efficient localized, isolated and continual delivery of vector to target tissues, provides
69 lving field of medicine, as evidenced by the continual development of new surgical and nonsurgical tr
73 ber of atoms in a molecule), there have been continual efforts to reduce its complexity either by imp
74 mics of a piRNA master locus open the way to continual emergence of new patterns of piRNA biogenesis
77 splay both the features of anergy induced by continual engagement of the B-cell receptor (BCR), such
79 dic engagement with most partners instead of continual engagement, and reducing costs by providing ne
82 hat treatment strategies offering modest but continual enhancement of reservoir clearance rates resul
83 undergraduate life science curricula is the continual evaluation and development of courses that ref
85 bal public health threat, largely due to the continual evolution of escape from preexisting immunity
86 plants that are resistant to pests, but the continual evolution of pathogens creates the need to ite
87 ection, and B cells counter this mutation by continual evolution to restore recognition, serendipitou
91 to other secondary lymphoid tissues in their continual exposure to an enormous diversity of microbiom
92 ed in Chinese/French bilinguals who have had continual exposure to Chinese since birth and differed f
94 cells generated in this manner depends upon continual exposure to high Ag levels and that such cells
95 ntigen-presenting cells may be suppressed by continual exposure to microbial products from the gut, i
97 gene should occur at sites that ensure their continual expression in the absence of any unwanted side
102 structure phenotypes, a consequence of their continual folding and unfolding, and these phenotypes ha
103 e production of the peroxo intermediate with continual formation of the mineral core until the availa
104 hat also drives lipid synthesis leads to the continual formation of triazole phospholipids and membra
105 hrough a tightly stacked Golgi that involves continual fusion and fission of stable, "like" subcompar
107 tasis is maintained by a balance between the continual generation of new cells and their elimination.
108 paration is accomplished in part through the continual generation of new neurons, which, due to a tra
109 nsequence of adaptation to an environment of continual genotoxic stress encountered in its habitat.
111 of the F ring's morphology results from the continual gravitational and collisional effects of small
112 ves against Alzheimer's disease), there is a continual growing demand for new chemical syntheses, whi
113 Shh production and signaling in driving the continual growth and expansion of the hindbrain choroid
115 d with regenerative efforts characterized by continual hepatocyte proliferation and often has adverse
116 page would give a hyperlink to it), and the continual high rates of birth and death of pages on the
117 master regulators of differentiation through continual histone deacetylation in stem cells enables se
119 architecture is highly plastic and requires continual homeostatic signaling to maintain its basal fu
120 og's craniofacial diversity is the result of continual human intervention in natural selection, a pro
121 immune response in the healthy host despite continual immune surveillance dictates that immune respo
123 mics and next-generation sequencing data and continual improvement in measures of environmental expos
124 itting the model to new data has resulted in continual improvement in parameter estimates, which curr
128 of the protein synthesis that allows for the continual incorporation of new amino acids to the growin
129 f both humans and nonhuman primates showed a continual increase at late times after injection, a resu
137 he diversity of life on Earth is a result of continual innovations in molecular networks influencing
138 eptors to the cell surface, thereby allowing continual integration of signaling and Ag recognition.
139 velopment before locomotion that reflect the continual integration of spinal neurons into a functiona
141 es are usually applied in environments under continual invasion pressure where the number, size and l
142 iogenesis-impaired MDCK cells do not undergo continual junction remodeling, and mature cilia are not
143 y, we focus attention on the importance of a continual learning process and the use of robust control
145 bacteria, amoebae, and fibroblasts display a continual level of energy-consuming reactions involving
147 -inhibited photopolymerization to generate a continual liquid interface of uncured resin between the
150 s, granule cells, and interneurons, ensuring continual modulatory influence by nicotinic mechanisms t
151 These findings underscore the importance of continual molecular surveillance of RSV in order to gain
152 ass spectroscopy cannot satisfy the needs of continual monitoring as they are labor-intensive and not
155 r auditory world to be stable despite almost continual movement of the head demonstrates the efficien
156 es) should drive molecular evolution through continual natural selection for adaptation and counter-a
159 The olfactory neuroepithelium undergoes continual neurogenesis and, after extensive lesions, ful
162 photobleaching techniques to demonstrate the continual nuclear import of STAT6, independent of tyrosi
163 ay between two types of motors together with continual nucleation of MTs by chromosomes could organiz
164 modeling data indicates that the dynamics of continual nucleosome removal and reformation at the acti
167 of its brain, is thought to proceed through continual orchestration among diverse cell types as they
170 vidence for clinically beneficial effects of continual oxytocin administration on the core social sym
173 ess than the ATPase rate, accounting for the continual PCr decrease during anoxia in both muscles.
175 may be responsible for Titan's methane, the continual photochemical depletion of which furnishes Tit
176 hile being reeled in to spindle poles by the continual poleward flow of tubulin subunits driven by mi
178 of long-term memory, is predicted to require continual positive feedback in which PKMzeta enhances it
179 et phenotypes caused by (PR)50 required both continual (PR)50 expression and an aged cellular environ
180 how CCR6-positive Th17 cells maintain their continual presence in psoriasis through a positive chemo
181 methylation at a specific site requires the continual presence of an H3K9 histone methyltransferase.
185 but high diversity in the population places continual pressure on the virus in the reservoir species
186 ection against melanoma, indicating that the continual priming of naive T cells is not required for v
188 ial cells of the intestinal mucosa undergo a continual process of proliferation, differentiation, and
191 eas anti-class I responses were generated by continual processing of graft parenchymal cells; recogni
193 anism in leaf development, which ensures the continual production of mature leaves following juvenile
195 ral stem cells, an essential process for the continual production of neurons throughout life, remain
196 chronic mycobacterial infection through the continual production of terminal effector cells from a p
199 oantigenic priming, their ability to undergo continual proliferation and expansion was defective duri
201 indicating that netrin-4 participates in the continual propagation of this stem cell population.
204 mmunosensor with liver-on-chips to carry out continual quantification of biomarkers secreted from hep
207 y in actively moving populations through the continual realignment of cell polarity with the tissue a
209 anuary 2003 and September 2013 that used the continual reassessment method (CRM), CRM using escalatio
210 f this standard design and the time-to-event continual reassessment method (TITE-CRM) for dose-escala
214 on of dnaC inhibits replication by promoting continual rebinding of DnaC to DnaB and consequent preve
216 ations in the lung airways are maintained by continual recruitment of new cells from the circulation.
218 ing proteins control cellular events through continual regulation of their activities within animals.
222 as of the environment, these tissues undergo continual rejuvenation through homeostasis, and, in addi
223 stability of blocked forks in vivo is due to continual reloading of the replication apparatus at the
224 This heterogeneity is a consequence of the continual remodeling and interconversion of HDL subpopul
225 and remain restricted to this layer, despite continual remodeling and shifting of their terminal arbo
228 thelium house the stem cells that ensure the continual renewal of the epithelial cells that line the
230 istory of biodiversity is characterized by a continual replacement of branches in the tree of life.
231 hrons during embryonic development relies on continual replenishment of progenitor cells throughout n
233 nes involved in beta cell function, but also continual repression of closely related endocrine gene p
237 hors with due credit and that can evolve via continual revision and traditional peer review into a ri
238 mesenchyme in the adult thymus, suggesting a continual role for mesenchymal cell-derived RA in postna
241 volving, functional viruses in milk indicate continual seeding of the mammary gland by blood virus va
242 that oocyte production is maintained through continual seeding of the ovary by circulating, bone-marr
243 which viruses shape their genomes under the continual selective pressure exerted by the host immune
244 triazole autocatalysis successfully leads to continual self-assembly of three-dimensional nanospheres
247 oblast differentiation additionally requires continual signaling from insulin-like growth factor (IGF
251 These findings indicate that SGD acts as a continual source of nutrients that can feed bloom-formin
256 is shifting from predominantly premarket to continual study throughout the total product life cycle.
258 al-to-cerebellar SUVRs in AD patients showed continual substantial increases through 30 min after adm
262 r self-renewal and the capacity to produce a continual supply of cytolytic effector progeny until all
263 R) or chimeric antigen receptors generates a continual supply of effector T cells, potentially provid
265 r human infections and stresses the need for continual surveillance as a component of prepandemic pla
266 homa (cHL) provide signals essential for the continual survival of the neoplastic Hodgkin and Reed-St
268 ls resident in nonlymphoid tissues depend on continual TCR signaling for their survival and function,
271 HIV-1 a concern for infected individuals on continual therapy, but it is an emerging problem in reso
273 iotic resistance in pathogenic bacteria is a continual threat to human health, often residing in extr
276 into a niche is a key factor for growth and continual tissue renewal during development, sustenance,
280 hloroplast membrane lipids and in part, by a continual transfer of TAG or fatty acids derived from CL
282 o disclose the key mechanisms underlying the continual transition towards a state of heart failure.
283 is acute and often associated with disease, continual transmission of these viruses in nature depend
286 th nonsynaptic regions (over minutes) and by continual turnover of cell surface receptors (over hours
288 adult mice are mitotically active, implying continual turnover, differentiation, and replacement of
290 neficial, and that recommendations will need continual updating as further data become available.
291 on to start or terminate a meal involves the continual updating of information on current body status
293 -driven just-in-time delivery of case carts, continual updating of preference lists based on utilizat
294 task performance, as this task requires the continual updating of the contents of one's current ment
296 erized by sequential population turnover and continual viral adaptation, a scenario readily comparabl
298 of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tin
299 g one 24 h sleep/wake cycle prior to 24 h of continual wakefulness under highly controlled environmen
300 reakdown rate categories, potentially due to continual water availability in streams and rivers modul
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