ライフサイエンスコーパス: continuous flow

1 13)C and heteronuclear NMR experiments under continuous flow.

2 ective acoustic impedance of single cells in continuous flow.

3 ual catalysis, has been developed for use in continuous flow.

4 ibiotics than those grown in MWP without the continuous flow.

5 DMSO allowed the protocol to be performed in continuous flow.

6 been developed using photoredox catalysis in continuous flow.

7 We demonstrate a continuous-flow acoustophoretic separation of 300 and 10

8 A continuous flow adaptation was found to offer improved r

9 an existing glaciochemical analysis system, continuous flow analysis (CFA) of ice-cores.

10 The combination of continuous flow and a stationary magnet enables a degree

11 e describe the assembly and use of a modular continuous flow apparatus from readily available and aff

12 namide as a catalytic cosolvent for biphasic continuous-flow applications.

13 oligosaccharides (FOS) was developed using a continuous-flow approach based on an immobilized whole c

14 ked enzyme crystals (CLECs), able to work in continuous flow, as a highly sensitive, robust, reusable

15 ITP-based surface hybridization to standard continuous flow-based hybridization and experimentally d

16 also experiments can easily be performed in continuous flow because of the stripline's favorable geo

17 N(-) loadings, we established and operated a continuous-flow bioreactor fed increasing loadings of SC

18 Continuous-flow bioreactors were commissioned and tested

19 es into zones opens up new opportunities for continuous-flow biosynthesis.

20 platelet deposition and thrombus growth in a continuous flow blood pump and thereby replicate pattern

21 a centrifugal, fully magnetically levitated, continuous-flow blood pump engineered to enhance hemocom

22 ts were performed in batch (dip-and-dry) and continuous (flow-cell) processes, and binding performanc

23 c scans may be predictive of mortality after continuous flow (CF) left ventricular assist device (LVA

24 ere we report the development of a multistep continuous-flow CGMP (current good manufacturing practic

25 The development and application of continuous flow chemistry methods for synthesis is a rap

26 d most relevant developments in the field of continuous flow chemistry with the focus on hazardous re

27 Channel-fouling is a pervasive problem in continuous flow chemistry, causing poor product control

28 of the Heck-Matsuda reaction carried out by continuous-flow chemistry between aryl diazonium salts g

29 This continuous-flow cluster chip will enable further studies

30 a cryogenic purge and trap system coupled to continuous flow compound-specific stable carbon isotope

31 mides from sulfinamides under both batch and continuous flow conditions is described.

32 hat allows one to record transition times in continuous flow conditions without the necessity to stop

33 diborylarenes on gram scales under batch and continuous flow conditions.

34 hallenges by growing 2D COF thin films under continuous flow conditions.

35 reaction, performed both in batch and under continuous flow conditions.

36 ble products selectivity were achieved under continuous flow conditions.

37 showed a dramatic drop after FI compared to continuous flow conditions.

38 esults were compared to those obtained under continuous flow conditions.

39 aziridinations can be easily achieved under continuous-flow conditions.

40 ce of the three-dimensional structures under continuous-flow conditions.

41 Here we developed a continuous-flow culture apparatus (Nutrostat) for mainta

42 ium triflates was achieved using a practical continuous-flow design.

43 r-sized droplets with enzyme substrates in a continuous-flow device.

44 In older children, intracorporeal continuous flow devices (e.g., HeartMate II Left Ventric

45 pattern was observed with both pulsatile and continuous-flow devices.

46 in eGFR was observed with both pulsatile and continuous-flow devices.

47 ces have been replaced with newer-generation continuous-flow devices.

48 We describe the benefits of an online continuous flow differential electrochemical mass spectr

49 Here we propose a barcode-free continuous flow droplet microfluidic platform to suit th

50 We present a continuous-flow droplet-based digital Enzyme-Linked Olig

51 ophyllene), were investigated in a series of continuous flow experiments in a 10 m(3) indoor Teflon c

52 We evaluated a continuous-flow external ventricular assist device (VAD)

53 ponse to a one unit pH shift in experimental continuous flow fermentors inoculated with human faecal

54 fined mode for a finite volume of liquid and continuous flow for scalability purposes.

55 sing, was employed to carry out the LDR in a continuous flow format with online single-molecule detec

56 in a commercial beer sample in a real-time, continuous flow format.

57 simple microfluidic chip for derivatization, continuous flow-gated injection, separation, and detecti

58 This technique performs continuous-flow, high throughput affinity-separation of

59 This technique performs continuous-flow, high throughput size based sorting of m

60 In this work, a continuous-flow, high-throughput, automated C. elegans a

61 Studies were performed by continuous flow hydride generation coupled with atomic s

62 on and accelerated trypsin digestion using a continuous flow immobilized enzyme reactor (cf-IMER).

63 a hybrid mass-mobility instrument in which a continuous-flow ion mobility classifier is used as a fro

64 rbon isotopic signatures were measured using continuous flow isotope ratio mass spectrometry.

65 Use of continuous flow leads to isolation of the desired compou

66 ective review of all patients supported by a continuous flow left ventricular assist device (Heart Ma

67 ncing ventricular arrhythmias (VAs) while on continuous flow left ventricular assist device (LVAD) su

68 ce and management of AI in 232 patients with continuous flow left ventricular assist device at our in

69 d for at least 30 days and </=18 months by a continuous flow left ventricular assist device from June

70 In a population at risk, higher DOPBP during continuous flow left ventricular assist device support w

71 e substantial morbidity and mortality during continuous flow left ventricular assist device support y

72 or angiotensin receptor blocker usage during continuous flow left ventricular assist device support,

73 Hematologic adverse events are common during continuous flow left ventricular assist device support;

74 increasingly recognized as a complication of continuous flow left ventricular assist device support;

75 and in patients undergoing implantation of a continuous flow left ventricular assist device.

76 AI is common in patients with continuous flow left ventricular assist devices and may

77 fibrillator (ICD) in patients supported by a continuous-flow left ventricular assist device (CF-LVAD)

78 ments were made in triplicate among 60 axial continuous-flow left ventricular assist device (HeartMat

79 trointestinal angiodysplasia develops during continuous-flow left ventricular assist device (LVAD) su

80 ist device (RVAD) use in patients undergoing continuous-flow left ventricular assist device (LVAD) su

81 vely investigate the longitudinal effects of continuous-flow left ventricular assist device (LVAD) un

82 s one of the most common complications after continuous-flow left ventricular assist device implantat

83 s used to identify adult patients undergoing continuous-flow left ventricular assist device implantat

84 he setting of suspected device thrombosis in continuous-flow left ventricular assist device patients

85 ication of antithrombotic therapy identifies continuous-flow left ventricular assist device patients

86 A retrospective review of Heartmate II continuous-flow left ventricular assist device patients

87 icenter, retrospective analysis evaluated 51 continuous-flow left ventricular assist device patients

88 vasive blood pressure (BP) measurement among continuous-flow left ventricular assist device patients.

89 changes (200-400 revolutions per minute) in continuous-flow left ventricular assist device pump spee

90 Patients with continuous-flow left ventricular assist device receiving

91 uality of life and survival of patients with continuous-flow left ventricular assist devices (CF-LVAD

92 botic and bleeding outcomes in patients with continuous-flow left ventricular assist devices (CF-LVAD

93 its accuracy is unverified in patients with continuous-flow left ventricular assist devices (CF-LVAD

94 e most common adverse event in patients with continuous-flow left ventricular assist devices (LVADs)

95 he structure of the aorta from patients with continuous-flow left ventricular assist devices (LVADs)

96 Continuous-flow left ventricular assist devices (LVADs)

97 of morbidity and mortality in patients with continuous-flow left ventricular assist devices (LVADs).

98 Continuous-flow left ventricular assist devices have rep

99 Conveying the complex trade-offs of continuous-flow left ventricular assist devices is chall

100 Estimated actuarial survival after continuous-flow left ventricular assist devices ranged f

101 The totality of data for continuous-flow left ventricular assist devices show con

102 3 women (54 +/- 14 years) with Heartmate II continuous-flow left ventricular assist devices underwen

103 Among subjects with continuous-flow left ventricular assist devices, the res

104 49/367 patients implanted with Heartmate II continuous-flow left ventricular assist devices.

105 ummarize the current evidence on outcomes of continuous-flow left ventricular assist devices.

106 Continuous-flow left ventricular assist systems increase

107 ctly into a formed liquid microjunction of a continuous flow liquid microjunction surface sampling pr

108 In this Letter, we demonstrate continuous-flow liquid microjunction mass spectrometry i

109 Mass spectrometry imaging by use of continuous-flow liquid microjunction sampling at discret

110 Continuous-flow liquid phase oxidation chemistry in micr

111 an age, 58.3+/-8.0 years), 7 patients with a continuous-flow LVAD (HF+LVAD group: mean, 57.7+/-5.6 ye

112 sed humans, cows, and sheep supported with a continuous-flow LVAD (n=9 LVAD, n=11 control).

113 the basis of the approval date of the first continuous-flow LVAD for bridge to transplantation in th

114 heart failure who required support with the continuous-flow LVAD HeartMate II (Thoratec Corp, Pleasa

115 d pulsatility in patients supported with the continuous-flow LVAD HeartMate II is associated with an

116 ectively reviewed 247 patients who underwent continuous-flow LVAD implantation from January 2005 to D

117 udy examined whether mechanical unloading by continuous-flow LVAD leads to myocardial atrophy.

118 ne, and sustainability of changes induced by continuous-flow LVAD on the structure and function of th

119 Among continuous-flow LVAD patients without aortic valve openi

120 gh-volume implantation centers, totaling 295 continuous-flow LVAD recipients with >/=2 cholesterol va

121 Initiation of continuous-flow LVAD support was associated with signifi

122 gastrointestinal vascularity develops during continuous-flow LVAD support.

123 cal functional data indicated that prolonged continuous-flow LVAD unloading does not induce hypertrop

124 Continuous-flow LVAD unloading induced in a subset of pa

125 ic heart failure requiring implantation of a continuous-flow LVAD were prospectively enrolled.

126 NICM, n = 93) requiring durable support with continuous-flow LVAD were prospectively evaluated with s

127 ifty-eight male patients-18 implanted with a continuous-flow LVAD, 16 patients with LVAD explanted (r

128 n patients, cows, and sheep supported with a continuous-flow LVAD.

129 indings in multiple species supported with a continuous-flow LVAD.

130 METHODS AND A single-center continuous flow-LVAD database (n=354) was used to identi

131 Of 9976 patients undergoing continuous-flow-LVAD implantation, 386 patients (3.9%) r

132 ed Circulatory Support who underwent primary continuous-flow-LVAD surgery were examined for concurren

133 some degree of arterial pulsatility, even in continuous flow LVADs may be necessary to achieve optima

134 ty found in the second and third-generation, continuous flow LVADs, along with improved survival rate

135 With the introduction of newer continuous flow LVADs, with lower morbidity, neurologica

136 VAs are common in patients with continuous flow LVADs.

137 Contemporary continuous-flow LVADs alter blood flow dynamics and card

138 nts of adult patients implanted with durable continuous-flow LVADs as bridge to transplant, destinati

139 In the current era, patients with continuous-flow LVADs had mortality similar to that of s

140 ardium in heart failure patients unloaded by continuous-flow LVADs has not been studied.

141 Candidates supported with contemporary continuous-flow LVADs have favorable waiting list outcom

142 with pulsatile-flow LVADs; and patients with continuous-flow LVADs.

143 8 reverse-phase mini-column was coupled to a continuous flow manifold to carry out the on-line SPE an

144 ization protocol employed a phase separation/continuous flow manifold whose advantages include cataly

145 C was loaded into the injection valve of the continuous flow manifold.

146 isecting single Stentor coeruleus cells in a continuous-flow manner.

147 So it can be beneficial to perform continuous flow measurements in this setup for analysis

148 Persistent low-level hemolysis (LLH) during continuous-flow mechanical circulatory support is associ

149 analysis (1 measure every 2 s), the CF-MIMS (Continuous Flow Membrane Inlet Mass Spectrometer) is an

150 inter-reaction solvent exchange achieved by continuous flow membrane units.

151 exposure to CO2, we demonstrate a scalable, continuous flow, membraneless particle filtration proces

152 A continuous-flow method for the regioselective arylation

153 The use of continuous-flow methods has allowed the deprotonation of

154 We present a continuous-flow microelectroextraction flow cell that al

155 driven Ru(bpy)3(PF6)2 catalyzed photocascade continuous flow microfluidic approach that involves the

156 inding and base flipping kinetics within the continuous flow microfluidic mixer, with results showing

157 e apply these principles toward developing a continuous flow microfluidic platform that enables trans

158 Here, an integrated continuous-flow microfluidic assay is developed to effec

159 Using continuous-flow microfluidic mixing, we have now observe

160 Continuous-flow, microfluidic reactions in capillary tub

161 e of a microfluidic NMR chip hyphenated to a continuous-flow microreactor and is based on the capabil

162 se in miniaturized stirred batch reactors or continuous flow microreactors.

163 pects of liquid phase oxidation chemistry in continuous-flow microreactors is given.

164 evaluated the effect of an industrial scale continuous flow microwave volumetric heating system in c

165 fer between residue 110 and the heme using a continuous flow mixer.

166 The development of a continuous flow multistep strategy for the synthesis of

167 Monitoring is enabled using a continuous-flow nanoelectrospray (CF-nESI) probe contain

168 id structures from different precursors, and continuous-flow nanomanufacturing with the potential for

169 nt from the LC column is mixed online with a continuous flow of (13)C-enriched sodium bicarbonate, an

170 h single- and double-analyte solutions under continuous flow of buffer.

171 Because of the novel design of the device, a continuous flow of cells is uniformly distributed into p

172 By providing a continuous flow of electrons, the proteoliposome experim

173 gas is transferred through the membrane to a continuous flow of high purity nitrogen, which is then m

174 and the elongation of these fibrils under a continuous flow of monomer solution (rate approximately

175 being routinely updated to keep up with the continuous flow of new data in GenBank and RefSeq.

176 ted cisternae and tubules while supporting a continuous flow of newly synthesized proteins and lipids

177 rs incubation with fresh nutrients in MWP or continuous flow of nutrients in DFR.

178 an respiratory epithelial cells (HREC) and a continuous flow of nutrients, mimicking the microenviron

179 terized by the absence and the presence of a continuous flow of nutrients, respectively.

180 Xe production and should allow for on-demand continuous flow of purified and highly spin-polarized (1

181 Here we show that a continuous flow of reactant solution leads to by far the

182 ion of perception.SIGNIFICANCE STATEMENT The continuous flow of sensory input is not processed in an

183 an ambient ionization technique based on the continuous flow of solvent using an in situ microextract

184 uction of the platform is designed such that continuous flow of sweat can pass through an array of fl

185 nected to commercial technical pens to allow continuous flow of the ink, thereby increasing the print

186 Continuous flow of the organic phase increases the inter

187 are fractionated into numerous droplets in a continuous flowing oil phase.

188 y a vinylogous Mannich reaction performed in continuous flow on chip.

189 s of 5 muL to be sequentially measured under continuous flow, opening the method to fast and reliable

190 However, achieving efficient continuous-flow operation and size-based fractionation o

191 Implementation of the PBT-2 catalyst in a continuous-flow packed-bed reactor achieved nearly 60000

192 nished charge transfer resistance, the all-V continuous-flow PESC was capable of producing 20% gain

193 In addition, the advantages of continuous-flow photochemistry are pointed out and a tho

194 Continuous-flow photochemistry in microreactors receives

195 Here we demonstrated an all-vanadium (all-V) continuous-flow photoelectrochemical storage cell (PESC)

196 nanocrystalline suspension in water using a continuous flow photoreactor shows that the large-scale

197 The first continuous flow pinacol coupling reaction of carbonyl co

198 agnetic bead actuation for DNA analysis in a continuous flow platform with minimal technical requirem

199 Although continuous flow platforms are commercially available, sy

200 The translation of batch chemistries onto continuous flow platforms requires addressing the issues

201 The employment of continuous-flow platforms for synthetic chemistry is bec

202 h process was successfully translated into a continuous flow process allowing efficient preparation o

203 The development of a continuous flow process for the multistep synthesis of a

204 e reagents, an efficient and high-throughput continuous flow process was developed to perform a dual

205 A micro-continuous-flow process was applied for the preparation

206 he polymer morphology, a relevant metric for continuous flow processes.

207 olutions were used in two distinct multistep continuous-flow processes (amidation and Mg-I exchange/n

208 l route that incorporated many advantages of continuous-flow processes to produce active pharmaceutic

209 ulting in homogeneous solutions suitable for continuous flow processing.

210 of this synthesis expand the capabilities of continuous-flow processing, including a Friedel-Crafts a

211 ated excellent stability during five days of continuous-flow processing.

212 Recent advances in continuous-flow processors, which integrate sustainabili

213 Towards multi-step transformations in continuous flow, proteins were arrayed as ordered zones

214 A continuous flow protocol for the direct stoichiometric e

215 A safe, practical, and scalable continuous flow protocol for the in situ generation of d

216 An efficient continuous flow protocol has been developed for bond C-H

217 To address this, a new continuous flow protocol was developed that eliminates t

218 A continuous-flow protocol for the bromination of benzylic

219 A continuous-flow protocol for the light-induced fluorinat

220 A continuous-flow protocol for the preparation of organic

221 A portable continuous-flow prototype built in an aluminum flight ca

222 ailure to receive either the new centrifugal continuous-flow pump or a commercially available axial c

223 Recent innovations in continuous-flow pump technology have not only contribute

224 of a new magnetically levitated centrifugal continuous-flow pump that was engineered to avert thromb

225 -flow pump or a commercially available axial continuous-flow pump.

226 e-flow electrophoresis (mFFE) is a promising continuous-flow purification technique that is well suit

227 ching were addressed by designing a suitable continuous flow reaction setup for both types of transfo

228 In a continuous-flow reaction with an empty-bed contact time

229 ows for analytical pulse flow or preparative continuous flow reactions.

230 Smaller batch and larger-scale continuous-flow reactions require only a limited amount

231 ene and propene) or higher hydrocarbons in a continuous flow reactor below 375 degrees C over H-SAPO-

232 otochemical process can be performed using a continuous flow reactor which facilitates carrying out r

233 reaction can be successfully adapted into a continuous flow reactor which is applicable for large-sc

234 ntal precursor concentrations (2.4 ppb) in a continuous flow reactor.

235 harides was overcome by using a microfluidic continuous flow reactor.

236 d Phoenix high-temperature and high-pressure continuous flow reactor.

237 The intensification of the process in a continuous-flow reactor increases the products' yields u

238 tetrachloroethene (PCE) and excess H(2) in a continuous-flow reactor.

239 Finally, the scale-up potential for continuous-flow reactors is described.

240 is given of photochemical transformations in continuous-flow reactors, including applications in orga

241 ic systems were investigated using batch and continuous-flow reactors.

242 kocytes from platelet-rich plasma (PRP) in a continuous flow regime.

243 en to microfluidic platforms operating under continuous flow regimes, droplet-based methods, valve-ba

244 Continuous flow requires local remodeling through crossl

245 Focus was placed on a continuous-flow sand-packed column in which a uniform di

246 performing this decarboxylative reaction in continuous flow, scale-up of the reaction could be achie

247 tested under highly resistive media using a continuous flow set up, as well as when subjecting it to

248 Application of the methodology in a continuous-flow setup achieves comparable yields to thos

249 We demonstrate herein a continuous-flow shape-based separation of spherical and

250 The model was then transposed to long-term continuous flow simulations using the software PHREEQC.

251 nfinity-corrected reflective objective and a continuous flow solvent probe coupled to a Fourier trans

252 We propose the use of a continuous-flow sorting strategy to facilitate future co

253 Because silent gaps are not common in continuous flowing speech, the cognitive/linguistic rest

254 e significantly reduced compared to standard continuous flow spotting technologies as well as in comp

255 The phase separation/continuous flow strategy afforded similar yields at 100-

256 A phase separation/continuous flow strategy employing an oxidative Glaser-H

257 The adoption of and opportunities in continuous flow synthesis ('flow chemistry') have increa

258 Contrary to conventional wisdom, continuous flow synthesis based on droplets is expected

259 Continuous flow synthesis enables the safe handling of d

260 eduction of CO2 for the photoredox-catalysed continuous flow synthesis of alpha-amino acids.

261 A rapid and modular continuous flow synthesis of highly functionalized fluor

262 We describe an efficient continuous flow synthesis of ketones from CO2 and organo

263 rolysis is participating in the trend toward continuous flow synthesis, and this has led to a number

264 sive experience of single-step and multistep continuous flow synthesis, we also describe solutions to

265 Small-volume continuous-flow synthesis (small-volume CFS) offers a nu

266 an alternative approach, we report here the continuous-flow synthesis and formulation of active phar

267 A continuous-flow synthesis of aziridines by palladium-cat

268 pproach are substantial enabling advances in continuous-flow synthesis, complex multistep sequence te

269 tative PCR of mRNA from biofilms from a 24-h continuous flow system demonstrated a significantly incr

270 his protocol, a nonspecialist can assemble a continuous flow system from reactor coils, syringes, pum

271 Cl(-), NO3(-) and SO4(2-) in a melter-based continuous flow system separating the three analytes in

272 y of stainless-steel syringes, assembly of a continuous flow system with multiple junctions, and yiel

273 ductase activities, growth as a biofilm in a continuous flow system, as well as virulence in mouse bu

274 o detect a model compound, metergoline, in a continuous flow system.

275 monstrate the dynamic monitoring of ATP in a continuous-flow system exhibiting a fast response time,

276 kinetics of immune complexes' formation in a continuous-flow system using commonly available software

277 A continuous-flow system with timed injections was used to

278 ization has been established in a three-step continuous-flow system.

279 Continuous flow systems provide improved reaction safety

280 rge scale reactors based on MPS will require continuous flow systems where the properties of the supp

281 Although single-step transformations in continuous-flow systems are common, multi-step transform

282 ers now choose to mediate transformations in continuous-flow systems given the many benefits over rou

283 Utilizing this methodology, multi-step continuous-flow systems have improved the syntheses of a

284 preparation, photoresponsive gel design, and continuous flow technology, are summarized.

285 In addition, the safety aspects of continuous-flow technology are discussed.

286 rol of the metalation step, made possible by continuous-flow technology, allowed for the efficient pr

287 Inverse modeling of the continuous flow test enables us to quantify and rank the

288 Continuous flow tests are performed in two fixed-bed col

289 monstrates regeneration ability in long-term continuous flow tests.

290 nique for size fractionation of particles in continuous flow that has shown great potential for biolo

291 We show that in continuous flow the pulse delay is determined by the rep

292 pounds but should also be able to operate in continuous flow-through mode.

293 f (hetero)aromatics has been developed using continuous flow to generate a variety of aryl iodides.

294 heterogeneous particle or cell mixtures in a continuous flow using acoustophoresis.

295 tion intermediates, we have also developed a continuous flow variant of this method that is capable o

296 Continuous flow ventricular assist devices (cfVADs) prov

297 e update on the current state of short-term, continuous-flow ventricular assist devices (CF-VADs) in

298 spatially segregating attached enzymes in a continuous-flow, vortex fluidic device (VFD).

299 Once sprouting was initiated, continuous flow was needed to both sustain sprouting and

300 It enables cell transfer in a continuous flow, which aids the development of an automa