ライフサイエンスコーパス: contracture

1 ssure (LVEDP) by > or =20 mm Hg (ie, cardiac contracture).

2 er into rigor and developed greater ischemic contracture.

3 hat are critical in wound closure and tissue contracture.

4 ed ischemic contracture, and reduced maximum contracture.

5 RPC3-NFkB axis, leading to intractable wound contracture.

6 orrelated with severity of internal rotation contracture.

7 resulted in growth delay, muscle atrophy and contracture.

8 ist of phasic contractions overlying a tonic contracture.

9 duced forskolin-induced relaxation of the NA contracture.

10 erwent attempted surgical repair of capsular contracture.

11 umber of preconditioning cycles and ischemic contracture.

12 es and followed a predictable course of scar contracture.

13 els to identify the elements responsible for contracture.

14 a pathological response by muscle - namely, contracture.

15 breast implants is associated with capsular contracture.

16 11 hearts treated with CP plus Ran developed contracture.

17 ore significantly reduced than rapid cooling contractures.

18 y eroded skin, rocker bottom feet, and joint contractures.

19 flexed digits, crumpled ears and mild joint contractures.

20 e force versus [Ca(2+)](i) relations for KCl contractures.

21 in the development of radiation-induced leg contractures.

22 number of readmissions for reconstruction of contractures.

23 ing, defective eye movement and pectoral fin contractures.

24 acterized by early childhood onset and joint contractures.

25 ents with delayed motor milestones and ankle contractures.

26 nown causes of inherited multiple congenital contractures.

27 stimulation, as assessed by caffeine-induced contractures.

28 atter is additionally characterized by joint contractures.

29 els to developmental malformations and joint contractures.

30 re, but have been implicated in pathological contractures.

31 ontent and fibrosis, and decreased hind limb contractures.

32 Twelve patients had capsular contracture (57%).

33 The patient who had knee joint contractures achieved increased knee extension with pass

34 plex congenita is defined by the presence of contractures across two or more major joints and results

35 lays an important role in scarring and wound contracture after GFS.

36 tissues, metabolic changes in muscle during contracture, alterations in fatty acid metabolism during

37 l complications such as rupture and capsular contracture, although evidence increasingly points to a

38 for reasons other than significant capsular contracture, among which 1 (5%) had >or=20 CFU/10 ml son

39 ted were removed due to significant capsular contracture, among which 9 (33%) had >or=20 CFU bacteria

40 Complications include capsular contracture and calcification and possibly connective ti

41 h-mediated calcium overload, leading to cell contracture and death, and that application of the membr

42 ss and complications, including bladder neck contracture and deep venous thrombosis.

43 ventions such as cardioplegia delay ischemic contracture and improve postischemic contractile recover

44 myocardial A1ARs increased time-to-ischemic contracture and improved functional recovery during repe

45 legia (alone and in combination) on ischemic contracture and postischemic contractile recovery.

46 asty result in a high prevalence of capsular contracture and suboptimal cosmesis.

47 s a significant association between capsular contracture and the presence of bacteria on the implant.

48 arts increased to 89% when reperfused before contracture and to 56% when reperfused in the presence o

49 zed by congenital muscle weakness with joint contractures and coexisting distal joint hyperlaxity.

50 defects on extremities including congenital contractures and hypertonia.

51 ostridium histolyticum significantly reduced contractures and improved the range of motion in joints

52 ildhood-onset disease characterized by joint contractures and in some cases by abnormalities of cardi

53 s an XLID syndrome with fingertip arches and contractures and mapped to proximal Xq.

54 heads at relaxation; this may contribute to contractures and muscle weakness.

55 These were: presence of scapular winging, contractures and normal respiratory function.

56 ess in a humero-peroneal distribution, early contractures and prominent cardiomyopathy with conductio

57 progressive muscle disease characterized by contractures and proximal weakness, which can be caused

58 Additionally, structural soft tissue contractures and spinal deformities may develop from poo

59 d after 15 years old, with progressive joint contractures and spine deformities.

60 twitch skeletal muscles, thus causing muscle contractures and the development of the observed limb de

61 cal complications, such as rupture, capsular contracture, and breast pain, are unavailable.

62 to the myocyte perfusate caused tachycardia, contracture, and fibrillation of the cultured myocytes.

63 ine in ATP during ischemia, delayed ischemic contracture, and reduced maximum contracture.

64 sic CCA phenotype with arachnodactyly, joint contractures, and abnormal pinnae, whereas her daughter

65 nging, mild facial weakness, Achilles tendon contractures, and diminished or absent deep tendon refle

66 apy, bracing, soft tissue releases for joint contractures, and early stabilization of the spine.

67 icrocornea, optic atrophy, progressive joint contractures, and growth failure.

68 icrocornea, optic atrophy, progressive joint contractures, and growth failure.

69 , prednisone use at study entry, large joint contractures, and heart enlargement.

70 A video that contrasts kyphosis, gait, joint contractures, and mobility in mdx/utr(-/-) and alpha 7BX

71 r kidney disease, tendon friction rubs, hand contractures, and proximal muscle strength.

72 pigmentary retinal mottling; (4) congenital contractures; and (5) marked early hypertonia and sympto

73 ing body of evidence showing that congenital contractures are a shared outcome of prenatal defects in

74 postoperative complications and bladder neck contractures are excellent, and appear to be improved wh

75 ll muscle fails to induce twitches, however, contractures are induced by caffeine.

76 Contractures are reduced at low [Ca2+], unaffected by ad

77 The majority of bladder neck contractures are responsive to urethral dilation or cold

78 echanical stiffness, and therefore result in contracture, are unknown.

79 n hand function, inflammatory indices, joint contractures, arthritis signs, overall functional abilit

80 of the neck, elbows, and/or knees and joint contractures (arthrogryposis).

81 of the neck, elbows, and/or knees and joint contractures (arthrogryposis).

82 ese results question the utility of ischemic contracture as a predictor of the protective efficacy of

83 ocytosis and several syndromes with muscular contracture as a prominent feature.

84 ular resistance, and development of ischemic contracture as indicated by increases in left ventricula

85 ients affected by myopathy with early spinal contractures as a prominent feature.

86 asis of these syndromes redefines congenital contractures as unique defects of the sarcomere and prov

87 e, normal-glycogen hearts underwent ischemic contracture at 5 minutes, had an end-ischemic pH of 6.87

88 are short stature, a high incidence of joint contractures at birth and progressive scoliosis and frac

89 ed 1.5-fold and at the peak of acetylcholine contractures at the same lengths.

90 ity increased by about 80, 72 and 50% during contractures at the short, intermediate and long lengths

91 possible inclusion of early intervention for contracture avoidance and assistance with wound healing.

92 No differences were observed for KCl contractures between tissue types for either maximum for

93 During contractures, birefringence increased by 25 and 18% at t

94 stic and treatment concerns for bladder neck contractures (BNCs) in the prostate cancer survivor.

95 vestigations confirmed sclerotic skin, joint contractures, bone abnormalities, alopecia, and growth i

96 Hypoxia also relaxed GTPgammaS contractures but importantly, arteries could not be rela

97 ity, including itching, pain, stiffness, and contracture, but best management practices remain unclea

98 7632 (1 microm) relaxed GTPgammaS and Ca(2+) contractures; but the latter required a higher concentra

99 ecticides, and these materials induce muscle contracture by irreversible activation of the calcium-re

100 d enhance treatment for patients with muscle contracture caused by other conditions than high heel we

101 -based, nonsurgical option, may reduce joint contractures caused by Dupuytren's disease.

102 r involving cleft palate, neonatal seizures, contractures, central nervous system (CNS) structural ma

103 X-2(-/-) mice showed an increase in ischemic contracture compared with hearts from WT and COX-1(-/-)

104 agnosis between congenital Volkmann ischemic contracture (CVIC) and unilateral aplasia cutis congenit

105 was found between ECoG cycles and myometrial contracture cycles.

106 ese bacteria in the pathogenesis of capsular contracture deserves further study.

107 the most common of the heritable congenital-contracture disorders, and ~50% of cases are caused by m

108 odotoxin (1 micromol/L) also reduced cardiac contracture during ischemia/reperfusion, compared to CP

109 elay in the time to full ATP-depletion rigor contracture during severe hypoxia and enhanced morpholog

110 nificantly reduced the magnitude of ischemic contracture during ventricular fibrillation and the acco

111 t common known heritable cause of congenital contractures (e.g. clubfoot) and results from mutations

112 s cardioplegia has little effect on ischemic contracture, each affords similar protection of postisch

113 ry such as urinary incontinence, anastomotic contracture, erectile dysfunction and rectourethral fist

114 Case selection is critical because severe LR contracture, extensive scarring from prior strabismus su

115 e compliance and are susceptible to terminal contracture following mild passive extensions.

116 A subset of anastomotic contractures following radical prostatectomy are recurre

117 by 4-chloro-m-cresol (4-CmC)-evoked maximal contracture force in single intact fibers from the mouse

118 erences in tetanic, but not in 4-CmC-evoked, contracture forces were recorded in fibers from aging mi

119 These findings provide evidence that contracture formation is not the result of stiffening at

120 e characterized by multiple congenital joint contractures, frequently is caused by lesions in the per

121 onset autosomal dominant myopathy with joint contractures, has recently been localized to 21q in a se

122 lues for an increase in time to the onset of contracture in globally ischemic rat hearts.

123 neuromuscular junction, leading to a tetanic contracture in muscle fiber.

124 Arthrogryposis, defined as congenital joint contractures in 2 or more body areas, is a clinical sign

125 for persons with DA2A and perhaps congenital contractures in general.

126 itis, with severe loss of motion and flexion contractures in multiple joints.

127 y improvement of skin changes and knee joint contractures in patients with stage 5 chronic kidney dis

128 histidine), at 0.1-10 mM, provokes sustained contractures in rabbit saphenous vein rings with greater

129 susceptibility to caffeine- and heat-induced contractures in vitro.

130 urethral strictures (excluding bladder neck contracture) in this setting, as well as risk factors an

131 The 5-HT maximum tension (% of 80 mM KCl contracture) increased from 17 +/- 2% in non-pregnant to

132 on-ischemic murine hearts, prolongs ischemic contracture, increases postischemic recovery of LVDP, an

133 mia by hastening the development of ischemic contracture, increasing coronary vascular resistance, an

134 Hypertrophic scar contracture is considered to be a pathologic and exagger

135 Acceleration of ischemic contracture is conventionally accepted as a predictor of

136 Capsular contracture is the most common and frustrating complicat

137 [Ca(2+)](i) decline during caffeine-induced contractures is attributable to Ca(2+) transport by NaCa

138 most conditions characterized by congenital contractures is largely unknown.

139 ult in considerable morbidity owing to joint contracture, loss of flexibility, and disfigurement.

140 overlap disorders with joint hypermobility, contractures, mild skeletal dysplasia and high myopia.

141 ntly reported to cause "JMP" syndrome (joint contractures, muscle atrophy, microcytic anemia, and pan

142 inflammatory syndrome characterized by joint contractures, muscle atrophy, microcytic anemia, and pan

143 s, such as permanent dysaesthesia, ischaemic contractures, muscle dysfunction, loss of limb, and even

144 ng as early-onset joint hypermobility, joint contractures, muscle weakness and bone dysplasia as well

145 as supplied throughout ischemia, no ischemic contracture occurred, and postischemic recovery of contr

146 crements often represent the enlargement and contracture of channels rather than the opening and clos

147 In addition to the recurrence, he had contracture of the conjunctiva in the socket of his prev

148 We enrolled 308 patients with joint contractures of 20 degrees or more in this prospective,

149 oup of disorders characterized by congenital contractures of distal limbs without overt neurological

150 rden-Walker syndrome (MWKS), which encompass contractures of hands and feet, scoliosis, ophthalmopleg

151 e and myofiber histology and decreased fixed contractures of Lama2(-/-) mice.

152 of the palmar fascia, which leads to flexion contractures of the digits, and is associated with other

153 YH3 and characterized by multiple congenital contractures of the face and limbs and normal cognitive

154 1) is a disorder characterized by congenital contractures of the hands and feet for which few genes h

155 ned by us and is characterized by congenital contractures of the hands and feet, along with distincti

156 characterized by cleft palate and congenital contractures of the hands and feet.

157 is generally recommended for severe flexion contractures of the interphalangeal joints, other surgic

158 dular tumors, gingival fibromatosis, flexion contractures of the joints, and an accumulation of hyali

159 gical abnormalities" and for whom congenital contractures of the limbs and face, hypotonia, and globa

160 multiple pterygia, scoliosis, and congenital contractures of the limbs.

161 sorders characterized by multiple congenital contractures of the limbs.

162 infants have tremors with hypotonia and mild contractures of the shoulders and hips.

163 tory of the remaining cases is influenced by contractures of uninvolved muscle groups and subluxation

164 Contracture onset coincided with the decrease in glycoly

165 No patient had muscle contractures or Hirschsprung disease.

166 d/or toxicity of therapy; for example, joint contractures or joint damage may result in life-long dis

167 mily members with mutations had either joint contractures or skeletal myopathy.

168 % of patients with skin involvement, flexion contractures, or oral manifestations achieved complete o

169 particularly if sclerodermatous skin, joint contractures, or oral manifestations are present.

170 utaneous tumors, gingival hypertrophy, joint contractures, osteolysis, and osteoporosis.

171 ssociated with severity of internal rotation contracture (P <.001).

172 line (P = 0.0078) and changes in large joint contractures (P = 0.0072), tender joint counts (P = 0.01

173 In juveniles, scarring, contractures, persistent weakness, muscle dysfunction, a

174 ndons correlates with the bone fragility and contracture phenotype in humans.

175 outlet secondary to a recurrent bladder neck contracture postprostatectomy or cystectomy presents a r

176 erated whereas cardioplegia delayed ischemic contracture; preconditioning plus cardioplegia gave an i

177 Cariporide ameliorated ischemic contracture, prevented postresuscitation diastolic dysfu

178 MD) is an X-linked disorder characterized by contractures, progressive muscle weakness and cardiomyop

179 MD) is an X-linked disorder characterized by contractures, progressive weakness and cardiomyopathy.

180 ering from severe muscle weakness with joint contractures, pronounced growth retardation and kyphosis

181 Finally, wound healing time and contracture rate were reported.

182 after variable rest intervals, rapid cooling contractures (RCCs) and fast application of caffeine.

183 of lactate were studied using rapid cooling contractures (RCCs) and fast application of caffeine.

184 owever, notable shortcomings including graft contracture, recurrence, and impotence have been reporte

185 nts, correcting abnormal posture, preventing contractures, reducing pain, and improving function and

186 s and quality are abnormal and fractures and contractures result.

187 sterior urethral strictures and bladder neck contractures resulting from ablative therapies.

188 al condition characterized by multiple joint contractures resulting from reduced or absent fetal move

189 the ryanodine receptor (RyR1) display muscle contractures, rhabdomyolysis, and death in response to e

190 esia, shortening of all long bones, multiple contractures, rib anomalies, thoracic dysplasia, pulmona

191 r to repolarization-induced stop of caffeine contracture (RISC) in embryonic murine myoballs.

192 d for any of the following reasons: capsular contracture; rupture of the implant; hematoma or bleedin

193 pertrophy of calf muscles, progressive joint contractures, severe scoliosis, elevated serum creatine

194 ose that the definition of Volkmann ischemic contracture should be maintained only for the acquired f

195 address stone disease due to lower extremity contractures, spinal curvature, and pelvic tilt.

196 hanger and providing for the well-documented contracture-suppressant effect of the hormone on frog he

197 Lethal congenital contracture syndrome (LCCS) is a lethal autosomal recess

198 humans, GLE1 is mutated in lethal congenital contracture syndrome 1 (LCCS1) leading to prenatal death

199 Lethal congenital contracture syndrome 1 and lethal arthrogryposis with an

200 s causally linked to human lethal congenital contracture syndrome-1 (LCCS1); however, the resulting p

201 logy and pathogenesis of multiple-congenital-contracture syndromes.

202 developmental pathway that causes congenital-contracture syndromes.

203 ther with inherent drawbacks of the in-vitro contracture test confounded efforts to discover the unde

204 mbers by in vitro diagnostic pharmacological contracture testing of biopsied skeletal muscle.

205 and in mice mutant for fibrillin-2 is joint contractures that resolve over time.

206 , one of the most severe multiple congenital contracture (that is, arthrogryposis) syndromes, and nea

207 t disorder, characterized by twisting muscle contractures, that begins in childhood.

208 esses including disuse muscle atrophy, joint contractures, thromboembolic disease, and insulin resist

209 nteract to increase stiffness greatly of the contracture tissue in vivo.

210 The primary end point was a reduction in contracture to 0 to 5 degrees of full extension 30 days

211 ) reduces the force of a KCl (40 mM)-induced contracture to approximately 10% of the control value in

212 rial activity from low amplitude, infrequent contractures to high amplitude, high frequency contracti

213 sensitivity for activation, producing muscle contractures upon exposure to elevated temperatures.

214 The amplitude of caffeine-induced contractures, used to assess SR Ca(2+) load, was not sig

215 red to 54%, whereas in high-glycogen hearts, contracture was delayed to 13 minutes, the end-ischemic

216 hen cutaneous sclerosis, fasciitis, or joint contracture was first documented in the medical record.

217 Time to ischemic contracture was prolonged in the multipollutant-mixture

218 elationship for L-lactate showed that the NA contracture was relaxed by 50% at approximately 26 mM.

219 global ischemia, indexed by time-to-ischemic contracture, was accelerated by blocking adenosine recep

220 similar to familial dysautonomia as well as contractures, we identified a deleterious mutation in th

221 Progressive worsening of the proximal contractures, weakness, and a pectus carinatum deformity

222 Thus, times to 75% contracture were as follows: control, 14.3 +/- 0.4 minut

223 ventricular developed pressure and ischemic contracture were assessed with an intraventricular ballo

224 ogen hearts, ischemic glycogen depletion and contracture were avoided, and the hearts were protected

225 Finally, faster wound healing and less contracture were observed in animals treated with EPO 50

226 Puffy fingers and finger joint contractures were detected significantly more often in I

227 ickness score (MRSS), and knee joint flexion contractures were measured with a goniometer.

228 of 11 hearts treated with CP alone developed contracture, whereas 6 out of 11 hearts treated with CP

229 novel variant phenotypes, such as congenital contractures, which are potentially associated with Carn

230 nd cromakalim increased the time to onset of contracture with a similar potency (EC25, 11.0 and 8.8 m

231 A combination of proximal contractures with distal joint hyperlaxity is a distinct

232 racterized by generalized autosomal dominant contractures with limited eye movements, restrictive lun

233 ouette on radiograph (P = 0.04), large joint contractures (wrist, elbow, knee) (P = 0.008), and predn

234 in relevant science fields is in a state of contracture, yet many universities continue to maintain