ライフサイエンスコーパス: control element

1 m mRNAs containing the DICE (differentiation control element).

2 (controlling element), and peripheral plant (controlled element).

3 )-end turnover in addition to being an actin control element.

4 Bcl-6, which is a candidate site for such a control element.

5 gene by binding specifically to the internal control element.

6 rger than the minimal experimentally defined control element.

7 er these opposing elements form the intronic control element.

8 of Nanos mRNA, which contains a translation control element.

9 uggesting a possible repressor role for this control element.

10 ts polymerization by removing the inhibitory control element.

11 (3 cases) by using cinchonine as the chiral control element.

12 The E-Box is a widely used DNA control element.

13 ancer and at least one other transcriptional control element.

14 the 3'-UTR of COX-2 as a major translational control element.

15 he recently identified proteasome-associated control element.

16 e RNAP III terminator as an information-rich control element.

17 postulate that it functions as a regulatory control element.

18 nic mice using a chondrocyte-specific Col2a1 control element.

19 me hypertrophic chondrocyte-specific Col10a1 control element.

20 ored the use of DNA copy number as a circuit control element.

21 aline phosphatase using light as an external control element.

22 e first insight into a damage-based archaeal control element.

23 As, the miRNA synthesis rate is the dominant control element.

24 the understanding and application of genetic control elements.

25 ome cases overriding that of transcriptional control elements.

26 (SIs) to limit the action of transcriptional control elements.

27 ation about the context specificity of these control elements.

28 nesis, but little is known of the cis-acting control elements.

29 trongly suggesting interaction between these control elements.

30 he gene, its promoter or at the upstream cis-control elements.

31 sive tissue specificities and interdigitated control elements.

32 its, nucleic acid detection systems and gene control elements.

33 the apoE gene was mediated via distinct gene control elements.

34 d enhancers, which function as accessibility control elements.

35 re facilitated the approximation of intronic control elements.

36 ry domains, defined by a gene and its linked control elements.

37 nstrain interactions between transcriptional control elements.

38 f new types of biosensor devices and genetic control elements.

39 reat majority of which are not near exons or control elements.

40 tin loops to immobilized RNA polymerases and control elements.

41 whereas others did not, and represent novel control elements.

42 ented in consideration of steric and dipolar control elements.

43 ily identified the known splicing signals as control elements.

44 identify oligomers that comprise cis -acting control elements.

45 pression and antisense transcription as dual control elements.

46 icity of DNA methylation at these imprinting control elements.

47 ion of the rat TRIII gene to assess possible control elements.

48 scription initiation site also contain major control elements.

49 lecular sensors or as a new class of genetic control elements.

50 osage by overexpressing Dlk1 from endogenous control elements.

51 cture as well as incorporation of allosteric control elements.

52 is regulated by magnesium-responsive genetic control elements.

53 litate communication between transcriptional control elements.

54 conformation analysis in discovering new cis control elements.

55 sassembly of trans host factors with cis RNA control elements.

56 the recruitment of MED25 to transcriptional control elements.

57 ssembly strategy for this class of RNA-based control elements.

58 proper regulation of complex transcriptional control elements.

59 far focusing on using hydrogen bonds as the controlling element.

60 survival--is so inefficient, and to identify controlling elements.

61 and lentiviruses (HIV-1) have different size-controlling elements.

62 te the formation of adjacent gene expression controlling elements.

63 uster have identified a 320-bp amplification control element (ACE3) required for amplification, as we

64 C with both ACE3 and two other amplification control elements, AER-d and ACE1.

65 This exocyclic control element also contributes to the increased membra

66 ycline transactivator (TTA) acts as an inert control element and does not contribute to phenotypes un

67 The function of each accessibility-control element and the factors they recruit to remodel

68 -components are embedded among the hindbrain control elements and are highly diverged between species

69 a hybrid of quantum technologies composed of control elements and artificial-atoms.

70 The presence of translational control elements and cap structures has not been careful

71 Some locus control elements and enhancers transcribe lincRNAs, hint

72 s), recombining various post-transcriptional control elements and screening for the desired relative

73 inserted between eukaryotic transcriptional control elements and stably incorporated into the P. pas

74 nscription by pairing promoters with distant control elements and to orchestrate intrachromosomal rec

75 eocenters were used as removable atropisomer control elements and were installed by using a highly en

76 s of two subsystems: the central controller (controlling element), and peripheral plant (controlled e

77 pha3 gene via a cis-acting positive/negative control element, and the T-cell-specific CD8alpha gene v

78 tern is controlled by a number of long-range control elements, and is reflected in the severe homozyg

79 the defensin-1 cap site, for the presence of control elements, and we describe a minimal promoter (po

80 ncluding those without known function, their control elements, and, by inference, the proteins they e

81 and foreign promoters, and to show that Bmp5 control elements are capable of rescuing phenotypic effe

82 Critical cis-acting transcriptional control elements are located within a nuclease hypersens

83 Such control elements are operated by RNA-binding proteins (R

84 Imprinting control elements are proposed to exist within the KvLQT1

85 croarray on some tumor tissue and select the control element associated with the greatest amount of g

86 a establish a bioresource that links genetic control elements associated with normal immune traits to

87 ous TFs that are distributed along tRNA gene control elements, beginning upstream of the transcriptio

88 The similarity of genetic controlling elements between the CD21 and CD23 genes doe

89 that could find application as novel genetic-control elements, biosensor components or precision swit

90 H2B and H2A.Z are all acetylated at the cis-control elements but H3 remains unacetylated except at t

91 xpression, H4 acetylation appears at the cis-control elements but not at the Lys gene or its promoter

92 e increase the regulatory range of the Rnt1p control elements, by modifying a critical region for enz

93 These control elements can now be characterized in terms of th

94 three types of function: (i) conformational control elements comprising an RNA switch, (ii) self-fun

95 bility of cation-pi interactions to act as a controlling element decreases when Lewis acids coordinat

96 he 69 kDa isoform contains multiple putative control elements, deletion analysis and site directed mu

97 nslated region elements: the differentiation control elements (DICE) in Lox mRNA and the pyrimidine-r

98 l A beta oligomerization and show that these controlling elements differ between A beta 40 and A beta

99 a relatively simple array of transcriptional control elements, divided into proximal and distal regio

100 The pituitary-specific locus control elements DNase I-hypersensitive site I (HSI) and

101 level, indicating the presence of a negative control element downstream of the P(3) promoter sequence

102 on-off switch that can integrate with other control elements during integrin activation.

103 quence contains the known glucose-responsive control elements (E2:A3/4).

104 expression patterns, and the transcriptional control elements ("enhancers") that govern them, remain

105 nds that do not bind to this RNA replication control element fail to induce plasmid loss in vivo, whe

106 These results prove that the IG-DMR is a control element for all imprinted genes on the maternal

107 thylated region (IG-DMR) that is a candidate control element for an imprinted domain on distal mouse

108 id alcohols, based on the use of an internal control element for intramolecular reaction.

109 ts allow for the use of light as an external control element for pharmacological activity, which can

110 B12, and that it likely serves as a genetic control element for regulating expression of the 25-gene

111 electrostatic interaction provides a unique control element for selective C-H functionalization.

112 chicken beta-globin locus, cHS4, served as a control element for these assays.

113 f O-GlcNAc on Ser/Thr residues, is a dynamic control element for transcription repression, protein de

114 ion (OriP) has been implicated as a critical control element for viral transcription, as well as vira

115 fering membrane properties, suggesting novel control elements for biological and amyloid regulation o

116 trategy for quantitatively tailoring genetic control elements for broader integration within biologic

117 with a platform to genetically map the viral control elements for genetic variation in planta.

118 ecognized by RNA polymerase III in which all control elements for initiation are located in the 5'-fl

119 erface of the lipid bilayer are suggested as control elements for insertional depth and orientation o

120 cally the essential role of these long-range control elements for PAX6 expression.

121 upport a model where S12 and S13 function as control elements for the more ancient rRNA- and tRNA-dri

122 The controlling element for these proteins is a 20 bp 'marbo

123 resence of the Delta(5)-unsaturation are key controlling elements for the formation of the natural ca

124 e their protein counterparts, these RNA gene control elements form highly specific binding pockets fo

125 cagon gene through activation of a conserved control element found between nucleotides -77 to -51.

126 onstrate that in addition to transcriptional control elements, full developmental silencing of the hu

127 ne methyltransferase overrides accessibility control element function and cripples V(D)J recombinatio

128 complexes compensated for the accessibility-control element function of a promoter but not an enhanc

129 th previous studies of these transcriptional control elements, GFP was strongly and specifically expr

130 commitment is to characterize the cis-acting control elements governing the expression of CD4 and CD8

131 a rise in H3 acetylation throughout the cis-control elements; H4 and H2B acetylation remain substant

132 Although the presence of additional control elements has been postulated to regulate rearran

133 Several upstream and intragenic PAX6 control elements have been defined, generally through tr

134 Mesoderm-specific control elements have not been identified, and the role

135 Potential Irr binding sites with iron control element (ICE)-like motifs were found upstream an

136 s grown under iron limitation bound the iron control elements (ICE) within the promoters of blr7895 a

137 l requires (i) suitably proportioned movable control elements, (ii) a method for operating them on de

138 he largely ignored amino-terminal helix is a control element in AsLOV2's light-activated conformation

139 Planar chirality remains an underutilized control element in asymmetric catalysis.

140 aster transcriptional regulator is a central control element in Caulobacter cell cycle progression an

141 ctivity by remote protecting groups and as a control element in enzymic processes for glycosidic bond

142 e 2'-hydroxyl of FAD can serve as a critical control element in flavoenzyme catalysis.

143 to a metal is often a key driving force and control element in many important reactions including as

144 tline the molecular polaron's potential as a control element in phononic circuitry architecture.

145 yl ligand of the iodonium salt as a critical control element in selectivity is presented.

146 Thus, the Cys loop acts as a key control element in the allosteric transduction pathway f

147 This residue acted as a key control element in the allosteric transduction pathway f

148 The master control element in the decision to sporulate is the resp

149 esults suggest that TSPAN33 represents a new control element in the development of inflammation by ma

150 We previously described a control element in the granulocyte-macrophage colony-sti

151 The response regulator Spo0A is the master control element in the initiation of sporulation in Baci

152 al candidate factors that recognize the MPEX control element in the Muscle creatine kinase (MCK) prom

153 resented data suggest that CcpA is a central control element in this important developmental process

154 Negative translational control elements in 3'UTRs regulate pattern formation, c

155 mmunoprecipitation assay, and regulates Il10 control elements in a reporter assay.

156 emes of animal crosses by combination of two control elements in a single transgene.

157 and enhancers, which serve as accessibility-control elements in antigen-receptor loci.

158 define interactions between transcriptional control elements in eukaryotic genomes.

159 ogenous Ig light chain (IgL) transcriptional control elements in GCV/SHM in the chicken B cell line D

160 in (ori) shares a common theme with many DNA control elements in having multiple binding sites for on

161 mma-globin gene under beta-globin regulatory control elements in hematopoietic stem cells (HSCs) resu

162 on of artificial networks of transcriptional control elements in living cells represents a new fronti

163 ontain structures remarkably similar to rRNA control elements in other organisms.

164 viruses have been postulated to function as control elements in RNA replication, transcription, and

165 f reports on 5' terminal posttranscriptional control elements in spleen necrosis virus and human foam

166 enting these engineered RNA molecules as key control elements in synthetic genetic networks are highl

167 e and is homologous to related translational control elements in the 5'-UTR of the light and and heav

168 Furthermore, manipulation of potential control elements in the context of a single integration

169 Rab GTPases serve as major control elements in the coordination and definition of s

170 constructs we identified two transcriptional control elements in the first 500 bp of intron 1.

171 to the Igkappa locus, known transcriptional control elements in the Iglambda locus lack functional N

172 upstream of Nrl, we identified putative cis-control elements in the Nrl promoter/enhancer region by

173 on the molecular axle act as strict kinetic control elements in the self-assembly, thereby dictating

174 t to Hh, implying the existence of separable control elements in the sr gene.

175 re the dominant class of ligands and the key controlling element in asymmetric homogeneous transition

176 n germline and points to a possible deletion-controlling element in the beta-globin gene separate fro

177 ecombination reactions and, in some cases, a controlling element in transcription and the initiation

178 evealed evidence for peptide determinants as controlling elements in LacdiNAc biosynthesis, we report

179 s are subject to developmental control, like controlling elements in maize.

180 ed the presence of potential tissue-specific control elements including a consensus sequence found in

181 at least 5 distinct types of functional cis-control elements, including a binding site for the Notch

182 so describe a complex series of hierarchical control element interactions that orchestrate CD4 expres

183 been integrated with an adjacent araC-P(BAD) control element into the bacterial chromosome allows dyn

184 The integration of flow control elements into low-cost biosensors presents a sig

185 n channels, suggesting that beta2Glu155 is a control element involved in coupling ligand binding to c

186 phase transition via the Site II cell cycle control element is distinct from E2F-dependent mechanism

187 The exocyclic control element is employed along with a strategic place

188 Hoxc8 EE reported here and a transcriptional control element located in the Hoxd11 region.

189 A critical control element, located between -96 and -88, interacts

190 ion 1 to 96 was analyzed, and some important control elements may have been missed.

191 al level and that cis-acting transcriptional control elements mediating fauA iron repressibility resi

192 s satisfy the prediction of the cassette and controlling element models that genetic information is t

193 Riboswitches are a class of metabolism control elements mostly found in bacteria.

194 able radiopharmaceuticals, discusses quality control elements needed to optimize the study, summarize

195 Acetylation is thus concentrated at the cis-control elements, not at the Lys gene or its immediate p

196 Imprinted genes and their control elements occur in clusters in the mammalian geno

197 HIF-2alpha expression in keratinocytes is a control element of both tissue perfusion and systemic ar

198 sotope-controlled selectivity (ICS), a novel control element of chemical reactivity where a molecular

199 A major control element of the human c-myc oncogene is the nucle

200 The results obtained indicated that the Agr control element of the sed promoter resides within the -

201 geted sequences function as distantly-acting control elements of antisense long non-coding RNAs, whic

202 ns, respectively, and may serve as molecular control elements of bacterial cell lysis.

203 , and that these proteins serve as molecular control elements of bacterial programmed cell death.

204 Of the transcriptional control elements of D. melanogaster PCNA, we found that

205 l GTPases have recently emerged as important control elements of many stages of vesicular trafficking

206 , and further fine mapping revealed that the control elements of mutation frequency reside within the

207 atRA, Ajuba can be readily found at the RARE control elements of RAR endogenous target genes.

208 n a specific immune cell lineage, based upon control elements of the colony stimulating factor 1 rece

209 nd YodB, that target the cis-acting negative control elements of the P(3) promoter.

210 To elucidate the transcriptional control elements of the type VII collagen gene (Col7a1),

211 Some examples of precisely controlled elements of macromolecular architecture, such

212 alked portion of the predivisional cell is a controlling element of Caulobacter asymmetry.

213 fusions in which lac was expressed from the controlling elements of upstream genes.

214 LQT1-AS) represents an additional imprinting control element or center in the human 11p15.5 and mouse

215 n a simple channel and does not require flow control elements or moving parts.

216 ly, we found no evidence for transcriptional control elements or transcriptional initiation in the in

217 This indicates that distinct cis-acting control elements participate in cell type-specific induc

218 tion with a 5' terminal post-transcriptional control element (PCE) for efficient translation.

219 (IRES) and 5' proximal post-transcriptional control element (PCE).

220 ation of proximal and distal transcriptional control elements permits lineage-specific and elevated b

221 Thus, this transcriptional control element promotes central tolerance both by furni

222 sites of intrinsic flexibility within a DNA control element provide hinges for its protein-directed

223 he M. tuberculosis enzyme lacks a C-terminal control element recently uncovered in E. coli gyrase and

224 ment, termed DICE (Downstream Immunoglobulin Control Element), reduces in vivo activity in B cells.

225 gical systems, and their levels are critical control elements, reflecting the interplay between trans

226 s via the introduction of specific structure control elements responsible for binding analyte molecul

227 on in skeletal muscles, we characterized the control elements responsible for the positionally restri

228 b1 prevented activator binding to insulin C1 control element sequences.

229 A breakdown of the steric and electronic control elements shows that a gearing effect in the tran

230 hput in vivo Screening PLatform for Intronic Control Elements (SPLICE) to identify 125 unique ISRE se

231 -Src occurs through distinct transcriptional control elements such as the serum response element (SRE

232 TR of human APP contains several interesting control elements, such as an acute box element, a CAGA b

233 of Bcl-2 and Bcl-xL expressed under similar control elements supports the model that antiapoptotic B

234 -loops within the nanos 3' UTR translational control element (TCE) act independently to direct transl

235 RNA is mediated by a bipartite translational control element (TCE) in its 3' untranslated region.

236 is mediated by a 90-nucleotide translational control element (TCE) in the nos 3' untranslated region

237 nos (nos) mRNA by a cis-acting Translational Control Element (TCE) in the nos 3'UTR is critical for a

238 We previously identified a novel TGF-beta control element (TCE) in the promoters of SMC differenti

239 A 90-nucleotide translational control element (TCE) mediates translational repression.

240 )6GG] and a transforming growth factor-beta1 control element (TCE) that are required for alpha-SMA ex

241 a conserved transforming growth factor-beta control element (TCE) within the 5'-region of the smooth

242 A translational control element (TCE) within the KLF4 3'-untranslated re

243 s repressed by a 90 nucleotide Translational Control Element (TCE), also in the 3'UTR.

244 e this secondary structure, or translational control element (TCE), that provide the 15 nucleotides r

245 n, the natural Smcp mRNA contains a positive control element that counteracts the inhibition of trans

246 (SNV) contains a unique posttranscriptional control element that facilitates Rev/Rev-responsive elem

247 ains a unique cis-acting posttranscriptional control element that interacts with hypothetical cellula

248 tions likely harbors a cis-acting imprinting control element that is necessary for establishing and/o

249 macroscopic valve is a device with a movable control element that regulates the flow of gases or liqu

250 ted region at exon 1A contains an imprinting control element that specifically regulates Gnas and com

251 results identify a novel posttranscriptional control element that uses a conserved cellular export me

252 ecently characterized Hoxb13 transcriptional control elements that are active in prostate luminal epi

253 tches are widespread metabolite-sensing gene control elements that are typically found in the 5' untr

254 circuit design is the number of independent control elements that can be combined together in a sing

255 witching oligonucleotides (SSOs) are genetic control elements that can be used to specifically contro

256 However, control elements that can operate without complete destr

257 Riboswitches are RNA-based genetic control elements that function via a conformational tran

258 n requires the identification of cis -acting control elements that modulate gene function.

259 To define control elements that regulate tissue-specific expressio

260 boswitches are metabolite-responsive genetic control elements that reside in the untranslated regions

261 Riboswitches are genetic control elements that usually reside in untranslated reg

262 posttranscriptionally regulated by multiple controlling elements that impede translation, including

263 ila and gene silencing in maize mediated by "controlling elements" (that is, transposable elements) l

264 adenylation requires a far-upstream splicing control element, the negative regulator of splicing (NRS

265 e G-rich strands of two such transcriptional control elements, the 5'-S1 nuclease-hypersensitive sile

266 avior called "optomotor response." As neural control elements, the large tangential horizontal system

267 genes contain core promoters with two basal control elements, the TATA box and the pyrimidine-rich i

268 Amplification control element third chromosome (ACE3) appears to funct

269 and smooth-muscle genes that lack known SRF control elements, thus further expanding the breadth of

270 the down-regulation of CTLA-4 as a possible control element to enhance early T cell expansion throug

271 tor (UBF), which interacts with the upstream control element to facilitate the assembly of the transc

272 met several obstacles: one is lack of a good control element to regulate replication, and the other i

273 uences act as a distinct posttranscriptional control element to stimulate gag RNA nuclear export and

274 potential for eIF4E and other translational control elements to mediate myc's transforming functions

275 other regions of the Bmp5 gene for potential control elements, to confirm the location of several ele

276 h findings of others that methylation within control elements typically negatively correlates with ge

277 cts that illustrate that the transcriptional control elements used by both pathways are contained wit

278 ably from novel native orthogonal biological control elements using quantitatively in-context charact

279 A related control element was isolated in the mouse Snrpn genomic

280 A proximal subgenomic control element was located just upstream of the RNA3 st

281 ntrolling RNA3 production (distal subgenomic control element) was identified 1.5 kb upstream, at nt 1

282 translation of ccnd1 mRNA, a G1/S checkpoint control element, was impaired by microinjection of ccnd1

283 To elucidate control elements, we deleted the 100-kb intergenic regio

284 lored region and to identify potential novel control elements, we physically mapped the most D-distal

285 t that, during evolution, cell-type-specific control elements were acquired by a simple growth-regula

286 ther potential positive- and negative-acting control elements were identified in area II after mutati

287 Multiple control elements were involved in activation of transcri

288 rter mRNA carrying protamine 1 translational-control elements were translated in a mosaic pattern.

289 is catalyst, are demonstrated to be powerful control elements when operating in combination in comple

290 The cDNAs contain translational control elements which are found in transcripts under ma

291 nsgenesis, and have identified two important control elements which reside about 9 kb upstream at the

292 intact human genes with all their long-range controlling elements which might give high levels of tis

293 Motion of the ring is influenced by several control elements whose force-generating capability is ba

294 perhaps surprisingly, share transcriptional control elements with the very cells they regulate.

295 scriptional regulation is often specified by control elements within mRNA 3'- untranslated regions (3

296 A series of control elements within the Ig H chain (Igh) locus has b

297 acid sequences; the evolution of expression control elements within the protein coding sequence of r

298 connecting the two sides of the membrane via control elements within the protein.

299 as determined by alleles at the X chromosome controlling element (Xce), a locus defined genetically b

300 t can be biased by alleles at the X-linked X controlling element (Xce).