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1 l diffusion rates to give systems capable of controlled release.
2 n for correlating structure with function in controlled release.
3 iety of applications ranging from sensors to controlled release.
4 design of surface coatings in the context of controlled release.
5 st line drug gemcitabine after heat mediated controlled release.
6 lly find analogous uses in encapsulation and controlled release.
7 ntial to ensure high quality and efficacy in controlled release.
8 ycol/poly(-caprolactone), allowing diffusion-controlled release.
9 es, proteins, small RNA molecules, and their controlled release.
10 priate therapeutic drug concentration with a controlled release.
11 (416 to 1001) and three journals (Journal of Controlled Release, Advanced Drug Delivery Reviews, and
12 ly improved its stability and contributed to controlled release after consumption by modifying vitami
13 ition, we describe the use of macrophages as controlled release agents upon stimulation by physical a
16 irmed the suitability of MSPs as support for controlled release and protection of bioactive molecules
17 viding the possibility of a spatiotemporally controlled release and protection of bound biomolecules.
18 dil is a feasible option for a non-invasive, controlled release and pulmonary preferential treatment
20 s and hence present unique opportunities for controlled-release and tissue-engineering applications.
23 lot results indicate that locally delivered, controlled-release antimicrobial treatment may improve t
24 able peptide hydrogel system may be used for controlled release applications as a carrier for therape
32 in, where physiological mechanisms impacting controlled release are incorporated to capture observed
36 hesized that combining i.LN vaccination with controlled release biomaterials permitting sustained dos
37 ne based-approach comprised of two synthetic controlled-release biomaterials, poly(lactide-co-glycoli
38 d code, to receive lacosamide monotherapy or controlled-release carbamazepine (carbamazepine-CR) twic
39 of two doses of phentermine plus topiramate controlled-release combination as an adjunct to diet and
43 ype mesoporous silica nanosphere-based (MSN) controlled-release delivery system has been synthesized
44 rectomy, with subcutaneous implantation of a controlled-release deoxycorticosterone acetate pellet, a
45 ncepts in the development of injectable PLGA controlled-release depots for peptides and proteins, and
46 An important poorly understood phenomenon in controlled-release depots involves the strong interactio
51 ars, there have been significant advances in controlled release dosage forms used for contraception.
55 elivery routes, less-frequent dosing through controlled-release drug delivery and improved drug targe
61 vedilol and metoprolol succinate (metoprolol controlled release/extended release [CR/XL]) on hemodyna
65 lating complex multidrug administration from controlled release films for localized delivery remains
66 an historical overview of drug delivery and controlled release followed by highlights of four emergi
68 a frontline chemo drug, into PLGA MPP, with controlled release for at least 4 days and negligible bu
69 ability against harsh conditions and provide controlled release for food/pharmaceutical applications.
70 tainers can act as inert packaging with slow/controlled release for virtually any type of encapsulati
71 illustrates an effective platform to produce controlled release formulation of anti-cancer drugs, and
72 biocompatible, biodegradable, and non-toxic controlled release formulation of ATRA for effective HCC
75 drug delivery systems have produced numerous controlled release formulations helping patients improve
77 In particular, this review focuses on (1) controlled release formulations that deliver natural sol
79 solution standard and for two novel topical controlled-release formulations in which the DEET active
80 the factors that contribute to the slow and controlled release from each class of particle, as well
81 stematic study to optimize encapsulation and controlled release from the polymer without compromising
82 in an indigenously prepared, biodegradable, controlled-release gel as an adjunct to scaling and root
83 in an indigenously prepared, biodegradable, controlled-release gel, as an adjunct to scaling and roo
87 ersity of chemical modifications, stability, controlled release, however limited drug loading capacit
92 h microsphere formulations exhibited erosion-controlled release in vitro, indicated by similar polyme
93 potential for facile production of low-cost controlled-release injectable depots for leuprolide and
94 rated into a methylcellulose vehicle for its controlled release into intrabony defect (IBD) sites as
95 adsorbed 1 microg TGF-beta1, suggesting that controlled release is effective at 10-fold less drug dos
98 he time of the first issue of the Journal of Controlled Release (JCR), polymeric drugs, polymer-drug
99 nd showcases the importance of tailoring the controlled release kinetics of the formulation to the ho
101 size selective separation and purification, controlled-release materials, sensors and catalysts, sca
102 lymers (SELPs) have been effectively used as controlled release matrices for the delivery of viruses
105 examined the in-vivo efficacy of a nebulised controlled-release microparticle formulation of heparin
110 elease oral formulation of DNP, called CRMP (controlled-release mitochondrial protonophore), that pro
112 erapeutics that can be self-assembled into a controlled release nanoparticle with abilities to delive
113 sponse of tumor cells to XRT, we developed a controlled-release nanoparticle drug delivery system usi
114 is to resolve component spectra, temperature-controlled release of 3-NBS through vesicle membranes co
115 readily encapsulated in nanoparticles, with controlled release of 89% of drug into media over three
116 d-supported catalytic system enabled locally controlled release of a fluorescent dye into the brain o
117 gical order-order transitions to achieve the controlled release of a model payload (e.g., silica nano
118 ed drug delivery platforms for sustained and controlled release of a plethora of therapeutic agents.
119 ated via temperature change, followed by the controlled release of affinity-captured targets back int
122 y system (PR-AuNPs-MSN) for the photoinduced controlled release of an anticancer drug, paclitaxel, in
123 neficial for many applications requiring the controlled release of an oxidizing species, e.g., microf
129 delivery vehicle, it was discovered that the controlled release of autoantigen was important for the
130 late the production of lactose-free food and controlled release of beta-galactosidase into lactose-in
131 iterion to corrective therapy was the steady controlled release of beta-glu and its diffusion through
132 self-healable materials, mesophases for the controlled release of bioactive compounds, or dynamic fu
133 ple for the general temporally and spatially controlled release of bioactive molecules, pharmacophore
135 to verify that laser irradiation facilitated controlled release of both hydrophobic and hydrophilic d
136 ivery system (BA-MSN) for glucose-responsive controlled release of both insulin and cyclic adenosine
137 nts in the Plasmodium life cycle rely on the controlled release of Ca(2)(+) from intracellular stores
141 tissue destruction, we hypothesized that the controlled release of CCL22 could also recruit Tregs to
142 erous cells has been targeted herein for the controlled release of chemotherapeutics at the tumour si
145 to target mitochondria of cells, resulted in controlled release of cisplatin from Platin-M locally in
147 hat, when placed into a meniscal defect, the controlled release of collagenase and PDGF-AB increases
148 s work shows one of the first examples of pH-controlled release of corrosion-inhibiting ions from an
151 uronal network capable of restoring feedback-controlled release of DA in the nigrostriatal system.
153 lerated and we successfully demonstrated the controlled release of dopamine over a period of four wee
155 ystems have been developed which can provide controlled release of drug for potentially long periods
156 mplexes have received much attention for the controlled release of drugs due to the remarkable abilit
157 s an important role in the encapsulation and controlled release of drugs from PLGA microparticles.
159 Herein we focus on reviewing advances in controlled release of drugs from tissue engineering plat
160 et system (TMUPS), using coated pellets, for controlled release of drugs is an effective therapeutic
161 found widespread use in applications such as controlled release of drugs, cosmetics, inks, pigments o
165 to their unique properties and potential for controlled release of encapsulated drugs and structure-s
168 ulation systems can positively influence the controlled release of food ingredients in food and nutri
169 cle based transfection approach functions by controlled release of gene regulatory elements from a 6
170 cell proliferation and viability, while the controlled release of GLN from the PLGA-GLN pellet resul
173 these results suggest that coacervate-based controlled release of HB-EGF may serve as a new therapy
174 mouse excisional full-thickness wound model, controlled release of HB-EGF within the wound significan
175 her molecular machines driven by ATP is that controlled release of hydrolysis products is essential f
177 tractive candidate for the encapsulation and controlled release of hydrophobic nutraceuticals and bio
180 ocarrier-based degradable hydrogels provided controlled release of lactic acid for several hours; how
181 degradable hydrogels were developed for the controlled release of lactic acid in the vagina of BV-in
182 copies of lactic acid per molecule provided controlled release of lactic acid with a maximum release
183 uncharacterized proteases might promote the controlled release of membrane-anchored regulatory prote
184 erve as a transmembrane delivery vehicle for controlled release of membrane-impermeable proteins in l
186 is critical in the retention and maturation-controlled release of neutrophils from the marrow, while
189 s, including decreased leaching of NO donor, controlled release of NO, and maintenance of ultra-low f
190 To summarize, with increased solubility and controlled release of olive leaf phenolic compounds thro
196 design of reagents and polymers that provide controlled release of phenols in environments that are l
197 merase II (Pol II) to promoters, through the controlled release of promoter-proximally paused Pol II
199 (PLGA) has most often been employed for the controlled release of protein formulations because of it
200 the main contributor for the observed highly controlled release of proteins that are otherwise rapidl
201 folds often use synthetic polymers to enable controlled release of proteins, but most synthetic deliv
203 of many metazoan genes is regulated through controlled release of RNA polymerase II (Pol II) that ha
204 he unique protecting role of surface sulfur, controlled release of S(2-) from Tu, and formation of NC
205 nto account when formulating, more precisely controlled release of SC injected biopharmaceuticals cou
206 gh comparisons between model predictions and controlled release of several drugs from various-sized m
207 drug-eluting stents (DES), which impart the controlled release of sirolimus or paclitaxel from durab
208 re may also contribute to the spatiotemporal controlled release of some of its components, which part
212 t, the prototype contact lenses demonstrated controlled release of the molecules studied, with zero-o
214 inflammatory M1 macrophages concomitant with controlled release of the payload of anti-inflammatory d
216 h, revealing their ability to participate in controlled release of their constituent nanostructures,
217 IR) has great potential for spatiotemporally controlled release of therapeutic agents, it has been ha
218 anoparticles (NPs) capable of targeting, and controlled release of therapeutic and diagnostic agents.
219 ding stable platforms for imaging agents and controlled release of therapeutic monolayer payloads.
221 nanoconstructs to reach their potential for controlled release of therapeutics and biological cleara
222 l to trigger plant immunity and suggest that controlled release of these molecules upon infection may
224 m through the simultaneous encapsulation and controlled release of two synergistic anticancer drugs u
225 future, local administration and sustained, controlled release of VEGF(165) may decrease amputations
226 Inter-subunit chemical switches modulate the controlled release of virus particles in the unusual hig
227 novel delivery systems for encapsulation and controlled release of volatile allyl isothiocyanate (AIT
230 ch issues of low bioavailability and limited controlled release opportunities are well known and have
231 tions of 3DOM materials, namely sorption and controlled release, optical and electrochemical sensors,
234 nd 2) this depot platform enabled long-term, controlled release over 4weeks (92-272mug/mL of MK2i).
235 ive encapsulation and enable sustained, dose-controlled release over 72 h under conditions mimicking
236 -inhibitor-polymer conjugate formulated into controlled-release particles that maximizes efficacy and
237 C (prednisolone 5 mg/kg/day via subcutaneous controlled-release pellet) or placebo for 14, 28, or 42
238 ubcutaneous substitution of E(2) by means of controlled-release pellets caused a strong increase in t
241 d the OCRMs with triple functions for oxygen controlled-release, phosphorus removal and less impact o
242 port that stabilization of FGF2 levels using controlled release PLGA microspheres improves expression
243 We synthesized a bioconjugate composed of controlled release polymer nanoparticles and aptamers an
244 e therapeutic targeting of drug encapsulated controlled release polymer particles in a cell- or tissu
245 These newer generations of targeted and controlled release polymeric NPs are now engineered to n
247 crease or decrease of KCNQ5 channel activity controlled release probability through alterations in re
249 indings have implications for all manners of controlled release processes, especially for site-specif
252 rable drug delivery systems enable on-demand controlled release profiles that may enhance therapeutic
253 ficiently deliver multiple therapeutics with controlled release properties and increased tumor deposi
254 y of the suture for surgical repair with the controlled release properties of a biodegradable polymer
255 ts were enrolled in the MERIT-HF (Metoprolol Controlled-Release Randomized Intervention Trial in Hear
256 d in an intact form from the scaffold with a controlled release rate and transfect cells in vitro.
258 l fiber-optic fluorescence sensor based on a controlled-release reagent for the determination of lith
259 used to connect alcohol-bearing molecules to controlled-release reagents, the linkage described in th
260 the mesoporous silica shell that allowed the controlled release, resulting in a NIR-responsive DNA-ga
261 Analysis of beta-galactosidase activity and controlled release reveals that chitosan-grafted hydroge
262 This review highlights the important role of controlled release science in development of reliable me
274 which was accomplished by local placement of controlled release systems that sustain a gradient of th
277 le delivery and discusses efforts to develop controlled-release systems for delivery of biopharmaceut
278 Thus, the inability to stabilize proteins in controlled-release systems represents a major obstacle i
285 monstrate the potential of these systems for controlled release, the release of Nile Red as a "model
289 iramate (7.5/46), or 15 mg phentermine/92 mg controlled-release topiramate (15/92)] to complete a tot
290 treatment [placebo, 7.5 mg phentermine/46 mg controlled-release topiramate (7.5/46), or 15 mg phenter
291 icient polymer photodegradation and remotely controlled release using near-IR laser light at an unpre
292 ucing synthetic formulation that consists of controlled release vehicles for IL-2, TGF-beta and rapam
293 is work, to ultimately develop site-specific controlled release vehicles for NO, the NO donor S-nitro
295 her evidence for an ion pairing mechanism of controlled release was provided through the measurement
296 evice for dry reagent storage and subsequent controlled release, we tested this device with the malar
297 ion (i.e., fractional uptake of enzyme), and controlled release were studied as a function of pH and
299 Light-activatable drugs offer the promise of controlled release with exquisite temporal and spatial r
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