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1 ain challenging to characterize directly and conveniently.
2 ely charged submicrometer capillary channels conveniently.
3 ng can be used to create surface-normal maps conveniently.
4 so that pipetting functions can be performed conveniently.
5  a way that the nonlinear oscillation occurs conveniently.
6 n mutations in C4A and C4B can be elucidated conveniently.
7 fied networks can be visualized in Cytoscape conveniently.
8                                              Conveniently, a stable, inexpensive, and commercially av
9                                     The tool conveniently accepts user-provided tracks for custom ann
10 at allows researchers to comprehensively and conveniently access and query information about drugs, a
11                     The 2,3-diketoesters are conveniently accessed from the corresponding alpha-diazo
12 d lymphoblastoid cell lines (LCLs) provide a conveniently accessible and renewable resource for funct
13 s and proven to be portable, economical, and conveniently accessible.
14 n of artificial metalloenzymes since this is conveniently achieved by self-assembly.
15                      It also allows users to conveniently adjust the ordering based on prior knowledg
16 the final mesoporous Pt@GC composites can be conveniently adjusted over a wide range by controlling t
17                 Visible (solar) light can be conveniently adopted, however, only when using colored o
18 level SAEs of COPD prevalence which could be conveniently aggregated to all other census geographic u
19  of alkyl phenyl thioethers or, usually less conveniently, alkyl halides with either aromatic radical
20               Inducible genetic fate mapping conveniently allows for the labeling of EBGNs throughout
21 step isothermal process has the potential to conveniently amplify a very limited amount of the RNA sa
22 ver, no optimal NGS approach is available to conveniently analyze low frequency mutations caused by D
23 eterocyclic aldehyde derivatives that can be conveniently analyzed with mass spectrometry.
24                             The findings are conveniently and compactly illustrated by the use of Ven
25 al strands form a node and can be configured conveniently and connected for complex topological const
26       Remarkably, mesopores can be generated conveniently and controllably by the coassembly of a lig
27             Such programmes can be delivered conveniently and cost-effectively as a self-guided digit
28   This label-free fluorescence aptasensor is conveniently and effectively applicable for analysis of
29 ed by using a tin-porphyrin photocatalyst to conveniently and effectively produce a large initial pop
30 format and tools for working with these data conveniently and efficiently are needed.
31 acid derivatives of IAA and IPA are prepared conveniently and efficiently by coupling of readily avai
32                                       How to conveniently and efficiently produce entanglement betwee
33 variety of retrieving methods to access data conveniently and for integrating biological interpretati
34       We report a UV-visible-based method to conveniently and inexpensively determine the number of D
35 cence of the as-prepared hydrogel allows for conveniently and non-invasively tracking and modeling it
36                  Met oxidation can be probed conveniently and quantitatively by NMR spectroscopy.
37                        This mixture could be conveniently and quantitatively converted into deprotect
38 tracer imaging and offers the opportunity to conveniently and rapidly characterize transport of gamma
39 luene, ethylbenzene, and o-xylene (BTEX) are conveniently and rapidly preconcentrated in the microdro
40 h both novel and well studied genomes can be conveniently and reliably solved with the help of the Ge
41 t is able to generate these data quickly and conveniently, and demonstrate its efficacy on accessions
42                                         Most conveniently applied in a reagent free manner, all sensi
43 hia coli and efficiently purified using XTEN conveniently as a purification tag.
44 rpose is to index the domain of sequences as conveniently as possible for our user community.
45 ies to Abeta aggregates (Ki = 4-30 nM), were conveniently assembled by "click chemistry." Two radioio
46  the 2,5-disubstituted THF ring (C8-C12) was conveniently assembled via a 1,2-n-triol cyclization str
47    A recombinant ligand fused with IgG-Fc is conveniently assembled with the force sensor through Pro
48 h N-alkyl derivatives, the resolution occurs conveniently at (or just below) room temperature and eit
49 Water-solubilizing groups could be installed conveniently at either the C-2 or C-3 position of the im
50  "classical" blood drawing, can be performed conveniently at home, and avoids cumbersome shipping and
51 idine, 22, to which various aryl thiols were conveniently attached at the 5-position via an oxidative
52                                This strategy conveniently avoids the isolation of the unstable 3,3-di
53                     The hydroperoxides could conveniently be converted to the corresponding alcohols
54                                  Reserve can conveniently be divided into two types: brain reserve, w
55 ls, has high DNA packaging capacity, and can conveniently be maintained and manipulated in prokaryoti
56                     Microfluidic systems can conveniently be used for rapid analysis of biological sa
57                        This polymer could be conveniently blended with traditional plasticized poly(v
58 tabase provides a user-friendly interface to conveniently browse, retrieve and download human autoant
59                                    Users can conveniently browse, search and download four categories
60 ,2-cis arabinofuranosides can be synthesized conveniently by conducting the reaction at lower tempera
61          Various syn-1,3-diols were prepared conveniently by reduction of beta-alkoxy ketones with Li
62              Motion on this timescale can be conveniently captured by the Lipari-Szabo order paramete
63 (hydrodeamination) of aromatic amines can be conveniently carried out by amination of the correspondi
64       Reactions of alkynes and azides can be conveniently carried out in a biphasic medium of CH(2)Cl
65 s way, cell size specific electroporation is conveniently carried out, contributing to a 2.5~3 fold i
66 et, we demonstrated how IM-MS can be used to conveniently characterize and identify the synthesis of
67  nanotubes, and graphene oxide sheets can be conveniently coassembled in water to yield a stable coll
68  Web server, nonproteomics investigators can conveniently collaborate with proteomics specialists to
69                                Analytes were conveniently collected on an electrostatic polymer filte
70  previously not be used in ALP assays can be conveniently colorimetrically detected with this assay.
71 t temperature and salinity variations can be conveniently combined to maximize the electrode potentia
72 ytosine FRET-pair, tC(O) and tCnitro, can be conveniently combined with the acceptor and donor of our
73                  Electrokinetic methods that conveniently concentrate charged analytes by orders of m
74 tiated with Et(3)B/O(2), and the reaction is conveniently conducted at room temperature in an open fl
75              The operation of these gates is conveniently connected to a fluorescent readout.
76 y important 1,4-benzodiazepine skeleton were conveniently constructed from 2-(arylamino)benzamides th
77 arious chromeno[2,3-b]indol-11(6H)-ones were conveniently constructed via phenyliodine(III) diacetate
78 The surface coverage of DNA molecules can be conveniently controlled by modulating the initial concen
79 er than in regular paper channels and can be conveniently controlled from 0 to several mm/s by balanc
80 adily available 1-mercapto-3-yn-2-ols 5 were conveniently converted into the corresponding thiophenes
81 ard fashion, the sulfinamides 27 and 28 were conveniently converted into the key amines 39 and 47 ove
82                       Carbonyl compounds are conveniently converted into their corresponding dimethyl
83 ormation of symmetric anhydrides, which were conveniently converted to amide derivatives in a one-pot
84 Furthermore, this CNG electrophoresis can be conveniently coupled to second-dimension sodium dodecyl
85 ielding to the linear core structures can be conveniently coupled without the need for purification s
86                  In the last step, they were conveniently cyclized into spirooxaphospholenes with one
87 only the usual regression models but it also conveniently deals with linear models in which predictor
88 cal filaments and crafted microrods has been conveniently deduced from the analysis of their thermal
89 butyrylglycerol , a triacylglycerol that was conveniently deprotected in ethanol with acrylic beads c
90            The overall reaction mechanism is conveniently described by a "wedge scheme", which is a m
91  high stability, and high specificity can be conveniently designed.
92 f thiol-functionalized biomolecules could be conveniently detected by fluorescence microscopy using t
93  PIM-1 as a model system that its Qst can be conveniently determined by in situ UV-vis optical transm
94 s) at the hydrogen reversible potential were conveniently determined from linear fit of ohmic-loss-co
95 ating an acid-labile linker which is used to conveniently develop optimized conditions leading to the
96  transmissible and the number of variants is conveniently discernible by sequence analysis of a small
97 ttle vector-based mutagenesis system, we can conveniently dissect roles of lesion bypass polymerases
98     This material can be solvent cast, as it conveniently dissolves in tetrahydrofuran (THF), an impo
99 nary vessels, and pathologically they can be conveniently divided into occluding and inflammatory typ
100                   The DNase 1:AuNCs could be conveniently employed as efficient and fast sensors to a
101                 In fruit flies, sleep can be conveniently estimated by measuring the locomotor activi
102 porates ARSER, JTK_CYCLE and Lomb-Scargle to conveniently evaluate periodicity in time-series data.
103 ers and CE methodologies may be used to more conveniently evaluate the binding between receptors and
104 s-the mono- and dimethylated peptides-can be conveniently evaluated.
105                      Analysis results can be conveniently exported as publication quality figures and
106 to as magnetophoretic mobility, which can be conveniently expressed as a fraction of the cell sedimen
107 turing of oxidized poly(dimethylsiloxane) to conveniently fabricate nanofluidic systems with arrays o
108  to the corresponding phosphopeptides can be conveniently followed by measuring the fluorescence pola
109   Unfortunately, techniques that can be used conveniently for protein complex/aggregate detection and
110 is simple and sensitive and can be scaled up conveniently for use in a multiwell plate format, allowi
111 rom the precursor alpha-amino acids or, more conveniently, from the corresponding 1,2-amino alcohols.
112                          Both compounds were conveniently functionalized with a carboxylic function a
113            The required pH gradient was thus conveniently generated by electrically controlling the c
114 eAl(BHT)2 propagator/catalyst pair, which is conveniently generated by in situ mixing of 2 with 2 equ
115 High concentrations of this species could be conveniently generated by treatment of readily available
116               Rhodium(II) azavinyl carbenes, conveniently generated from 1-sulfonyl-1,2,3-triazoles,
117                          Rh(I) carbenes were conveniently generated from readily available ynamides.
118 anic compound can be isolated (44 %) or more conveniently generated in situ by a deprotonation reacti
119                            The sulfates were conveniently generated in situ by dissolving the corresp
120               These new catalyst systems are conveniently generated in situ from the known metal prec
121  a quantum dot has an atomic p orbital which conveniently goes to zero at the location of all the nuc
122 tional phenotypes, allowing cardiologists to conveniently group them in broad descriptive categories.
123 ately 100 pm V(-1)) are thermally stable and conveniently grown by a simple physical vapour depositio
124                    Unlike photons, which are conveniently handled by mirrors and optical fibres witho
125 he fluorination of aliphatic C-H bonds using conveniently handled fluoride salts.
126  collagen gels are too weak to be sutured or conveniently handled for clinical applications.
127                       Alternatively and more conveniently, high-quality SERS data are obtained by spi
128 ations of the eigenmodes of propagation were conveniently identified as the orientation angles that p
129 ethods, this technology can more readily and conveniently identify a wide range of organisms.
130       This approach allows us to rapidly and conveniently identify S-ODNs or S2-ODNs that bind to pro
131 tware suite provides a comprehensive tool to conveniently implement and compare various genomic meta-
132                                      VRs are conveniently implemented in software, whereas the latera
133 e with the care of head injury patients, and conveniently implemented.
134 e with the care of head injury patients, and conveniently implemented.
135 osis, lesion length, and APPROACH score, may conveniently improve the prediction, beyond individual i
136 he Ascaris motility machinery can be studied conveniently in a cell-free in vitro system based on the
137        The hydroborations can be carried out conveniently in a variety of solvents.
138 ese catalysts, the same products were formed conveniently in one pot from diethylmalonate by cross-co
139 l cohorts to be predicted from samples taken conveniently in the abattoir.
140                           This allows one to conveniently incorporate known amounts of different acti
141  high yield over four synthetic steps and be conveniently incorporated into peptides by standard soli
142              Using this line, platelets were conveniently indicated at sites of induced stress by bet
143  Here we show that exceptional points can be conveniently induced in a photonic molecule laser by a s
144                           Such probes can be conveniently inserted at the DNA level, at different pos
145 art 'all-in-one' nanoporphyrin platform that conveniently integrates a broad range of clinically rele
146 es a RESTful API for programmatic access and conveniently integration in third-party software or work
147 ection of either purified integrins or, more conveniently, integrin-expressing cell lysates, which ar
148 techniques that allow protein dynamics to be conveniently interrogated.
149               Diethylene glycol spacers were conveniently introduced between the electroactive compon
150 inchona alkaloids in various solvents can be conveniently investigated via (19)F NMR spectroscopy.
151 e demonstrate that coherent spectroscopy can conveniently isolate and detect such hidden high-order p
152 s, in their hydrobromide salt form, could be conveniently isolated and purified by crystallization.
153 ate the glycopeptides, and the products were conveniently isolated and purified in the solid form.
154      Importantly, the KR's products could be conveniently isolated by exploiting varying solubility o
155 zoic acid, allyl acetate, and (S)-SEGPHOS is conveniently isolated by precipitation or through conven
156  to give excellent yields, all products were conveniently isolated from the reaction mixtures through
157  each parameter can be accounted by adapting conveniently its probability distribution function, whic
158                               This chemistry conveniently lends itself to the controlled intercalatio
159 we show that this fundamental restriction is conveniently lifted when working with non-Hermitian pote
160  a widely used clinical anticancer drug, was conveniently loaded into nanocarrier by intercalating in
161                  Given that CAD cells can be conveniently manipulated using standard molecular biolog
162 c acids or acyl chlorides are unstable, less conveniently manipulated/isolated, or are not commercial
163 adial augmentation index (AI r ) can be more conveniently measured compared with carotid-femoral puls
164 se advantages is that energy transfer can be conveniently measured using sensitized acceptor decay me
165 ce plasmon resonance (LSPR) extinction band, conveniently measured using transmission or reflection u
166                      The effector phases are conveniently modeled by the K/BxN serum transfer system,
167                 This practical method can be conveniently modified and applied to the characterizatio
168 y for drug delivery, whose reactivity can be conveniently modulated by choosing the appropriate steri
169  serum retinol levels in LRAT-/- mice can be conveniently modulated by the quantitative manipulation
170 sting coupled assays, that it can be used to conveniently monitor FDPS activity in a 96-well plate fo
171 escent protein cassette which can be used to conveniently monitor viral infection.
172 urely mechanical work by a nanodevice can be conveniently monitored by electronic measurement.
173                         Clearance rates were conveniently monitored by quantitative detection of Gd u
174  of these substrates is not accompanied by a conveniently monitored change in some physicochemical pr
175 ase in the fluorescein amine signal could be conveniently monitored in both noncontinuous and continu
176                             This reaction is conveniently monitored via 2H NMR spectroscopy.
177 es to be performed in solution, which may be conveniently monitored with conventional analytical tech
178            Caspase enzymatic activity can be conveniently monitored with peptidic chromogenic or fluo
179 trate S*, whose conversion to product can be conveniently monitored.
180                 The key compounds 11a,b were conveniently obtained by Stille coupling between 2,5-bis
181 heat for the endothermic bi-reforming can be conveniently obtained by the complete combustion of a qu
182 d fragment, 3-hydroxypent-4-enoic acid, were conveniently obtained through a lipase-catalyzed kinetic
183 ted; the latter intermediates/precursors are conveniently obtained through aldehyde-, alkylidene-, an
184 T-PCR assay was subsequently used to test 13 conveniently obtained tissue specimens collected sequent
185 easurements of corneal creep behavior can be conveniently obtained using MII at mechanical scale as s
186 idic and macroscopic systems respectively to conveniently perform parallel studies of EC response to
187 nd preformed enolate equivalents, and can be conveniently performed at room temperature in various so
188                             The reaction was conveniently performed at room temperature to give a ser
189 l improve such understanding, which could be conveniently performed by capillary electrophoresis (CE)
190 economic and human resources can nowadays be conveniently performed by mining the enormous amount of
191                         These operations are conveniently performed in a single flask in high yield.
192 l position of the fluorinated amino acid was conveniently performed under standard conditions, the ve
193 need for a cell-based EPAC assay that can be conveniently performed using microtiter plates for the d
194                    To detect biomarkers more conveniently, point-of-care (PoC) biosensors, which are
195                         The bridge region is conveniently positioned to modulate elastic fiber assemb
196               This chemistry is also used to conveniently prepare functionalized polystyrene beads ha
197 our members of the louisianin family, from a conveniently prepared 1,2,4-triazine and via a common te
198 rabinouridine through a methylene linker are conveniently prepared and incorporated into oligonucleot
199 athesis of the unprotected heterocycle and a conveniently prepared anomerically pure C1-vinyl 2-deoxy
200 he corresponding 2'-deoxy derivatives can be conveniently prepared by a reaction between sugar-protec
201 quinoline-substituted, unsaturated ester was conveniently prepared by a Suzuki-Miyaura coupling to fa
202                  Dihydropyridines 10a-c were conveniently prepared by reaction of 1 with Knoevenagel
203                      Dipp-Imd-BH(2)I is most conveniently prepared by reaction with diiodine while di
204       A series of alpha-sulfinylenamides was conveniently prepared by the condensation of a primary a
205       Immobilized pseudoephedrine amides are conveniently prepared by the one-step attachment of pseu
206 )I(OCOCF(3))(2) (n = 4, 6, 8, 10, 12) can be conveniently prepared by the oxidation of the correspond
207 ins, and 4-hydroxyquinolin-2(1H)-ones can be conveniently prepared by treatment of alpha-halocarboxyl
208         Various 1-arylbenziodoxolones can be conveniently prepared from 2-iodobenzoic acid and arenes
209                             New DPP dyes are conveniently prepared from commercially available pigmen
210                       2-CO and 2-NO are more conveniently prepared from Na/Hg reductions of 2-Cl in t
211       Single-stranded azide-labelled DNA was conveniently prepared from PCR products by lambda-exonuc
212 conjugated tetrazine derivatives that can be conveniently prepared from tetrazine building blocks and
213                      The central DHA core is conveniently prepared in a four-step synthesis starting
214  The 3'-phosphorothioamidites (2a-2d) can be conveniently prepared in good yields (86-99%) via a one-
215             The dimer of methylketene can be conveniently prepared in one step and high enantiomeric
216                   alpha-Amino nitrile 2a was conveniently prepared in two individual steps from chira
217 on: see text] Pentylidenecyclopentane can be conveniently prepared in up to 86% yield via the catalyt
218 -Substituted-2-ethoxy-1,3,4-oxadiazoles were conveniently prepared through a one-pot sequential N-acy
219 nd C-2 aryl 2'-deoxyinosine analogues can be conveniently prepared via the Pd-mediated cross-coupling
220                                       FHV is conveniently propagated in Drosophila melanogaster cells
221       This adduct could be rearranged to the conveniently protected amino carbonate 54 which is set u
222         As a result, the 3Drefine web server conveniently provides a useful tool easily accessible to
223         This functionalization strategy also conveniently provides access to a higher-order tris(porp
224 o not require additional reagents and can be conveniently quantified by flow cytometry and real-time
225             This facile method is useful for conveniently, quantitatively, and cost-effectively compa
226  service that software developers can use to conveniently query and access all data.
227 )-1,2,4-triazolo[4,3-a]pyridines, which were conveniently radiolabeled with carbon-11, as potential p
228     Passivation of semiconductor surfaces is conveniently realized by terminating surface dangling bo
229               In many cases, crystals can be conveniently recovered from the gels by using supramolec
230    Finally, the pseudoephedrine resin can be conveniently recycled and utilized with no significant l
231    Importantly, the SsADH-10 enzyme could be conveniently recycled by exploiting the differential sol
232 eweighted Markov chain Monte Carlo algorithm conveniently recycles posterior samples from the individ
233            The heteroaryl azides can also be conveniently reduced to heteroarylamines by aqueous ammo
234 g solids together with oxalic acid dihydrate conveniently releases acetic acid for purification by ga
235 chemistry for sarain A, but this problem was conveniently remedied by inverting the C-7' center via a
236 he emission from a dye coating, which can be conveniently removed afterward by rinsing without disrup
237  DBN hydrotetraphenylborate byproduct can be conveniently removed by filtration, providing pure N-acy
238 m vector or surrounding genomic regions) are conveniently removed in the returned alignment.
239 as a temporary stereodirecting group that is conveniently removed via benzylic hydrogenolysis concomi
240 on of permanent photoproducts that cannot be conveniently removed.
241 inyloxy (1c), is easily recovered and can be conveniently reoxidized to regenerate the oxoammonium sa
242 adily available racemic ketones 6 and 37 are conveniently resolved via their acetals with (R)-mandeli
243      This system opens new opportunities for conveniently resolving both transendothelial and transep
244         The output of red and green light is conveniently scored using a fluorescence plate reader.
245 reduced cost of this system will allow us to conveniently screen regulators of translesion DNA synthe
246 able of regulating HIV-1 reactivation may be conveniently screened.
247 uster sampling with unequal probabilities to conveniently select participants with desired characteri
248  on a total of 782 patient charts from three conveniently selected periodontal practices.
249  catalytic composite matrix structure can be conveniently separated from an aqueous environment after
250                     These gaps could be also conveniently sequenced, which is an important step in es
251 marginal effects of a disease that users can conveniently specify.
252 ls and technologies that can be manufactured conveniently, sterilized to minimize contamination and e
253 es cerevisiae continuous culture and is most conveniently studied by monitoring dissolved O(2) concen
254                         SCRAT can be used to conveniently summarize regulatory activities according t
255                                          Via conveniently synthesized 2,2'-anhydronucleosides, we hav
256  and haloarene-linked new triarylethenes are conveniently synthesized and presented as unsymmetricall
257                 Most of these compounds were conveniently synthesized by a Diels-Alder reaction of va
258 )C(6)H(4))(2)(CN)(2) (abbreviated PtC(2)) is conveniently synthesized by the thermal rearrangement of
259                              Compound 30 was conveniently synthesized by the treatment of benzyl-prot
260                                              Conveniently synthesized from protected primary amines,
261 s of 3-monofunctionalized 2-oxindoles 2 were conveniently synthesized from reactions between anilide
262 steine-based methacrylic monomer (CysMA) was conveniently synthesized via selective thia-Michael addi
263  throughout the dendritic skeleton have been conveniently synthesized.
264 r single-particle analysis so that users may conveniently tap into existing capabilities of the RELIO
265 fication in the absence of distinguishing or conveniently tested phenotypic characteristics.
266 ntly cheaper than alternative catalysts, and conveniently, the Li ribbon does not require the removal
267                                              Conveniently, the manipulation of the charge of the prot
268 national Prognostic Scoring System (or, more conveniently, the marrow blast percentage) can be used t
269                                         More conveniently, the square root of the flash titration end
270                                         More conveniently, this could be obtained directly with hNcaN
271                                              Conveniently, this strategy allows access to either keto
272                                              Conveniently, this unique reagent retains many of the pr
273 denum(VI) propylidyne complex 5 was prepared conveniently through a previously communicated reductive
274             The isolated single cells can be conveniently transferred into standard 96-/384-well plat
275 afford the corresponding enals, which can be conveniently transformed into azepanes under appropriate
276       The products of these reactions can be conveniently transformed to various useful polycarbocycl
277   Other functionalized derivatives were also conveniently transformed.
278  Some patients with overlap syndromes can be conveniently treated with triple fixed-dose combination
279 cleophilic N-heterocyclic carbenes have been conveniently used as catalyst modifiers in amination rea
280         In this context light signals can be conveniently used both for supplying energy to the syste
281 a 96-well microplate-based assay that can be conveniently used for high-throughput screening of sampl
282 represents a powerful technique which can be conveniently used for rapid extraction of mineral oil sa
283 ical methods based on the t test that can be conveniently used on high density array data to test for
284 c multivariable risk factor algorithm can be conveniently used to assess general CVD risk and risk of
285 e, because they contain submicron structures conveniently used to define optical resolution.
286              We revealed how HMM-DB could be conveniently used to derive a simplified energy landscap
287     Additionally, fluorescent test paper was conveniently used to detect cyanide in aqueous solution.
288 s, indicating that TOP1 transcripts could be conveniently used to monitor Top1 protein levels and act
289 igodeoxynucleotide has been developed, which conveniently uses routine activators and reagents.
290 ese new polymer-supported nucleosides can be conveniently utilized for diversity-oriented synthesis.
291 oup preferences of different sirtuins can be conveniently utilized to develop small molecules that se
292                       These results could be conveniently utilized to devise a novel class of (99m)Tc
293  image annotation system that enables one to conveniently visualize and annotate 3D volume objects in
294 r Prox1-expressing organs, and enabled us to conveniently visualize detailed structure and morphology
295   This reporter line has been widely used to conveniently visualize lymphatic vessels and other Prox1
296                             This information conveniently was presented in various textbooks.
297 ing can be varied dramatically, quickly, and conveniently while minimizing the tailing due to silanol
298 necting "sequence" to "folding", rapidly and conveniently, while exploring nonlinearities and other c
299 ssion intensity of the Au/substrate SPR mode-conveniently, without a spectrometer.
300 phospha-Michael additions were achieved very conveniently, without the need for an external strong ba

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