ライフサイエンスコーパス: convoluted

1 derm forms and the forebrain is enlarged and convoluted.

2 nge of brains, ranging from smooth to highly convoluted.

3 ive to the individual interactions can be de-convoluted.

4 s bend, while that with repeated sites has a convoluted 360 degrees turn.

5 loughing cells indicates they possess highly convoluted and blebbed plasma membranes, a morphological

6 ally studied in the simulation that would be convoluted and challenging in experiments.

7 ion was observed in glomerular cells, distal convoluted and collecting tubules, or medullary cells.

8 ctive Ca(2+) reabsorption in the late distal convoluted and connecting tubules (DCT2/CNT) is initiate

9 C expression is most prominent in the distal convoluted and connecting tubules of the kidney.

10 The highly convoluted and cytoarchitectonically diverse inferior fr

11 ant cells and cells with decondensed, highly convoluted and lobulated nuclei that are reminiscent of

12 opment, but during larval life lumens become convoluted and mature branches degenerate.

13 rovider incentives, information asymmetries, convoluted and opaque cost structures, and cultural atti

14 lic and basolateral staining of the proximal convoluted and straight tubule.

15 phron segments including glomeruli, proximal convoluted and straight tubules (PCT and PST), cortical

16 to other vertebrates, including the proximal convoluted and straight tubules (PCT, PST).

17 asmic space that can be greatly enlarged and convoluted, and an energized cytoplasmic membrane.

18 ous to soft, moist, heaped, deeply folded or convoluted, and orange-brown with a white, irregular mar

19 tric and is sometimes surprisingly variable, convoluted, and wantonly inefficient.

20 that included a notably shortened body axis, convoluted anterior neuroepithelium, caudal dysgenesis,

21 nderlies the expansion of the cortex and its convoluted appearance.

22 However, in a more convoluted application, polycyclic systems have arisen f

23 llenging because the experimental data are a convoluted average of contributions from multiple confor

24 s additional synthetic steps and costs, more convoluted behavior and effects in vivo, and also greate

25 eviously described as "vesicles" are in fact convoluted, branching chambers with complex and dynamic

26 ules involves many elementary steps, usually convoluted by diffusion processes.

27 r resolution interparticle distributions not convoluted by the intraparticle distribution.

28 While C 1s spectra were convoluted by the multiple chemical states of carbon pre

29 ons (PTMs) by bottom-up mass spectrometry is convoluted by the need for analogous derivatives and the

30 the design of SICM experiments, which may be convoluted by topographical and surface charge effects,

31 edia within compressed matrices had a broad, convoluted cell body and thin dendritic processes.

32 are thought to enable generation of larger, convoluted, cerebral cortices.

33 ertilization, sperm must traverse narrow and convoluted channels, filled with viscous fluids.

34 to the thick ascending limb of Henle, distal convoluted, connecting and cortical collecting tubules.

35 llelic to a previously described mutation in convoluted (conv), a gene required for epithelial morpho

36 Convoluted cortical gyri-like structures characterize th

37 nectivity, dynamic circuit operations, and a convoluted developmental assembly process rooted in the

38 Instead, they mediate a more globular or convoluted distribution of ER markers.

39 discontinuous domains; (4) closely packed or convoluted domain-domain interfaces; (5) structures with

40 ateral membranes appeared less vertical with convoluted edges versus control cells.

41 structural rearrangements guided by a highly convoluted energy landscape, the accurate mapping of whi

42 h a targeted deletion of Nf2 in the proximal convoluted epithelium using a Villin-Cre transgene.

43 in globular structures composed of a mass of convoluted ER tubules that maintain a connection with th

44 f photon-to-photon pair times as well as the convoluted ET model has been further demonstrated by sim

45 Convoluted exchange patterns are interpreted with the ai

46 Glycomics LC-MS data sets have convoluted extracted ion chromatograms that are challeng

47 o access exotic magnetisation states without convoluted fabrication and application processes.

48 The wide tubular network matures into a convoluted fenestrated sheet in a process that involves

49 usion with the parental plasma membrane, the convoluted fenestrated sheet is transformed into a plana

50 The array of convoluted fibrils in N. punctiforme may have an alterna

51 he predicted estradiol serum concentrations (convoluted from in vitro skin permeation data) were comp

52 que has been expanded to the coating of more convoluted geometries with high levels of tailored funct

53 on the surface of the cortex, where normally convoluted gyri are replaced by numerous (poly) and noti

54 Consumed worldwide, capsaicin has a long and convoluted history of controversy about whether its cons

55 ificial ice containing Melosira EPS revealed convoluted ice-pore morphologies of high fractal dimensi

56 sponse of the molecule and pull-off peak are convoluted in a single feature.

57 The unusual and convoluted interacting face of CD47, comprising the N te

58 hcb nets (chicken wire) or srs nets, forming convoluted intergrowths of multiple nets.

59 tures of these materials are dictated by the convoluted interplay of three key factors: (1) the overa

60 ing amino acid mass distributions (AMDs) are convoluted into peptide mass distributions (PMDs) during

61 , with the result that the brain is strongly convoluted into sulci and gyri.

62 The membranes generate a very convoluted intracellular architecture in which some of t

63 primary macrophages, HIV-1 Gag localizes to convoluted intracellular membrane structures termed viru

64 The crystal structure of IFIT5 revealed a convoluted intramolecular packing of eight TPRs as a fol

65 ompartments (VCCs), which largely consist of convoluted invaginations of the PM.

66 hat has a longer lifetime, to better resolve convoluted kinetic observations and allow us to draw cle

67 mal but individual branches contain multiple convoluted lumens.

68 led the FTE organoid to self-organize into a convoluted luminal structure, permitted matured differen

69 a great opportunity to understand the often convoluted mass of information pertaining to nanoparticl

70 d characterization elucidates the previously convoluted mechanisms of the solid-electrolyte interphas

71 ve of the Pasteurellaceae family, displays a convoluted membrane morphology.

72 Convoluted membranes were absent in dengue virus-infecte

73 structures such as double-membrane vesicles, convoluted membranes, and tubular structures.

74 ures, including double-membrane vesicles and convoluted membranes, are linked, respectively, with vir

75 include double-membrane vesicles (DMVs) and convoluted membranes.

76 he formation of double-membrane vesicles and convoluted membranes.

77 ding regions, nonstandard genetic codes, and convoluted modes of posttranscriptional modification and

78 The dendritic mitt enclosed an enormous, convoluted mossy fiber rosette forming many excitatory s

79 ages of Nostoc punctiforme revealed a highly convoluted, not parallel, fibrillar array.

80 Electron microscopy revealed extensively convoluted nuclear envelopes, intranuclear inclusions an

81 DNA synthesis, mitotic arrest, appearance of convoluted nuclei with decondensed DNA, and formation of

82 gh endoplasmic reticulum and Golgi, and less convoluted nuclei.

83 Oftentimes the enlarged regions are convoluted or partially septated.

84 ace of mesophyll cell walls adopt an unusual convoluted or undulated appearance, that PA14 cells orie

85 stered on the surface of LF and form a small convoluted patch with both hydrophobic and hydrophilic c

86 mmonia and pyridine follows a similar rather convoluted path in gas phase, with the formation of seve

87 s in the second set of topologies go through convoluted paths and are expected to experience great ki

88 pon movement patterns (e.g., straight versus convoluted paths) and/or their rates of movement (ROM) d

89 Understanding the mechanism of the brain's convoluted patterns can provide useful clues into normal

90 map onto the dorsal MOB, whereas the highly convoluted peripheral channels of the ethmoid turbinates

91 rs explore a greater volume of smaller, more convoluted pores, whereas larger dendrimers penetrate a

92 ively exist within a limited but complex and convoluted portion of the sample, such as occurs when co

93 The convoluted protein-protein and protein-DNA binding react

94 the lung and in Bowman's parietal cells and convoluted proximal tubules from the kidney.

95 mostly in the tubular epithelium of dilated, convoluted proximal tubules.

96 ntributions from adjacent layers generates a convoluted raw brightness that conceals the underlying b

97 ed sequencing data is complicated due to the convoluted read-outs and experiment-specific variation i

98 n organisms colonizing the lumen of proximal convoluted renal tubules at both 10 and 28 days postinfe

99 de --> sulfite --> sulfate, than with a more convoluted route that would result if sulfite were the p

100 at allows investigating surfaces of complex, convoluted samples such as living cells with minimal imp

101 /Cl(-) cotransporter, a marker of the distal convoluted segment of the kidney, the principal site of

102 er of lobules, which in turn are composed of convoluted seminiferous tubules.

103 the autocorrelation function and a proposed convoluted single-molecule interfacial electron-cation r

104 is the overlap of NMR resonances leading to "convoluted" spectra.

105 However, owing to the convoluted structure of DIA data sets, confident, system

106 nges from a simple straight tube to a highly convoluted structure will be the focus of this article.

107 The PCH of each individual species is convoluted successively to yield the PCH of the mixture.

108 The SiO(2) coating covers the highly convoluted surface of the TiO(2) conformally and with a

109 es and highlights how the unfolding of these convoluted surfaces contributes to physiologically relev

110 teurellaceae and Moraxellaceae families show convoluted surfaces.

111 and, from a mechanistic standpoint, far less convoluted than conventional protocols.

112 e available for diffusion in cytoplasm to be convoluted, thereby affecting macromolecule diffusivity.

113 d a coastline their flight path changed from convoluted to homeward oriented, so that most of them ev

114 dial glia in the neocortex but rather have a convoluted trajectory from the ventricle to the bulb sur

115 around fertilized eggs to the spermatheca--a convoluted tube where fertilization occurs.

116 Their convoluted tubular architecture is circumscribed by prox

117 pulmonary interstitial cells, renal proximal convoluted tubular cells, and crypt cells of the small i

118 The importance of the kidney distal convoluted tubule (DCT) and cortical collecting duct (CC

119 t-absorptive pathway in the mammalian distal convoluted tubule (DCT) and is the site of action of one

120 at WNK3 is expressed in the nephron's distal convoluted tubule (DCT) and stimulates NCC activity.

121 Na(+) transport in the renal distal convoluted tubule (DCT) by the thiazide-sensitive NaCl c

122 In kidney distal convoluted tubule (DCT) cells, stimulation of Na+/K(+)-A

123 NaCl cotransporter (NCC) of the renal distal convoluted tubule (DCT) controls ion homeostasis and art

124 , CD8(+) T cells directly contact the distal convoluted tubule (DCT) in the kidneys of DOCA-salt mice

125 m-chloride cotransporter (NCC) in the distal convoluted tubule (DCT) is solely responsible.

126 The mammalian distal convoluted tubule (DCT) makes an important contribution

127 transcellular Ca(2+) transport in the distal convoluted tubule (DCT) of the kidney.

128 The distal convoluted tubule (DCT) plays a critical role in renal s

129 Thiazide diuretic drugs act in the distal convoluted tubule (DCT) to inhibit a Na+Cl- cotransporte

130 ates Mg(2+) reabsorption in the renal distal convoluted tubule (DCT) via engagement of its receptor o

131 In the distal convoluted tubule (DCT), potassium imbalance causes WNK

132 showed that Pcbd1 is expressed in the distal convoluted tubule (DCT), where Pcbd1 transcript levels a

133 lciuria and marked hyperplasia of the distal convoluted tubule (DCT), whereas the opposite is true in

134 of the thick ascending limb (TAL) and distal convoluted tubule (DCT).

135 or alpha-Klotho (KL) localizes to the distal convoluted tubule (DCT).

136 in the apical plasma membrane of CON distal convoluted tubule (DCT).

137 ucial for calcium reabsorption in the distal convoluted tubule (DCT).

138 e major NaCl transport protein in the distal convoluted tubule (DCT).

139 Ca(2+) reabsorption via TRPV5 in the distal convoluted tubule (DCT).

140 The proximal convoluted tubule (PCT) and the medullary thick ascendin

141 The proximal convoluted tubule (PCT) reabsorbs most of the filtered b

142 t potassium reabsorption in the rat proximal convoluted tubule (PCT).

143 K-2Cl cotransporter [NKCC2]), and the distal convoluted tubule (the thiazide-sensitive Na-Cl cotransp

144 aquaporin-2, and pendrin showed that distal convoluted tubule and connecting segment cells, A-type i

145 n calcium entry into the cells of the distal convoluted tubule and connecting segment of the nephron,

146 MK K(+) channel did not change in the distal convoluted tubule and decreased slightly in the cortical

147 s not impair calcium transport in the distal convoluted tubule and indicates that thiazides should be

148 mediator of salt reabsorption in the distal convoluted tubule and is a key determinant of the blood

149 transcript was detected only in the proximal convoluted tubule and proximal straight tubule.

150 f the nephron, comprising part of the distal convoluted tubule and the connecting tubule, and regulat

151 r apical sodium transporters in the proximal convoluted tubule and the distal convoluted tubule of th

152 (+)-2Cl(-) cotransporter NKCC2 in the distal convoluted tubule and the thick ascending limb of Henle'

153 t, with their functional roles in the distal convoluted tubule and thick ascending limb, respectively

154 -sensitive Na-Cl cotransporter of the distal convoluted tubule appears to be the chief molecular targ

155 kidney, recent evidence points to the distal convoluted tubule as a possible site of mineralocorticoi

156 y for normal salt reabsorption in the distal convoluted tubule because of the need for K(+) recycling

157 ve Na+-Cl- cotransporter (NCC) of the distal convoluted tubule cause Gitelman's syndrome, an inherite

158 esults of siRNA transfection in mouse distal convoluted tubule cells and those of unilateral ureteral

159 expression model and in native murine distal convoluted tubule cells in culture.

160 In Cav1-/- mice, distal convoluted tubule cells were completely devoid of Cav1 a

161 h localized to the apical membrane of distal convoluted tubule cells, T58M Ncc localized primarily to

162 chief apical sodium entry pathway of distal convoluted tubule cells, we prepared an affinity-purifie

163 chemistry showed TSC labeling only in distal convoluted tubule cells.

164 atest accumulation of renox mRNA in proximal convoluted tubule epithelial cells.

165 conducting primary filtrate to the proximal convoluted tubule has been Bowman's space (BS) (1).

166 The distal convoluted tubule has been proposed to sense plasma [K(+

167 3 probes gave intense labeling of the distal convoluted tubule in pig kidney but (unexpectedly) no de

168 We conclude that the distal convoluted tubule is an important site of action of the

169 that potassium reabsorption in the proximal convoluted tubule is passive in nature and depends partl

170 he proximal convoluted tubule and the distal convoluted tubule of the kidney, respectively.

171 ing active Ca(2+) reabsorption in the distal convoluted tubule of the kidney.

172 dullary potassium channel in the late distal convoluted tubule of WNK1(+/FHHt) mice, which could cont

173 fect on lithium reabsorption in the proximal convoluted tubule or loop of Henle.

174 rgeting the thick ascending limb, the distal convoluted tubule or the collecting system.

175 agnesium (Mg(2+)) reabsorption in the distal convoluted tubule represents the final step before Mg(2+

176 region and caused an increase in late distal convoluted tubule volume.

177 tential difference (PD) at the late proximal convoluted tubule was +2.1 +/- 0.3 mV (lumen positive) a

178 hile fractional reabsorption in the proximal convoluted tubule was enhanced.

179 ium concentration ratio at the late proximal convoluted tubule was raised in the low-K+ animals (1.50

180 try revealed normal morphology of the distal convoluted tubule with reduced NCC expression.

181 ts in proximal tubule, loop of Henle, distal convoluted tubule, and cortical and medullary collecting

182 nding limb of Henle's loop and/or the distal convoluted tubule, and these disorders generate the grea

183 e SPAK mainly activates NCC along the distal convoluted tubule, but the kinases may compensate for ea

184 nd basolateral Rhcg expression in the distal convoluted tubule, connecting segment, and initial colle

185 ion and a decrease in the mass of the distal convoluted tubule, exclusive to DCT1.

186 important transporters in the renal proximal convoluted tubule, namely Na-H exchanger 3, Na-K ATPase,

187 ption in the thick ascending limb and distal convoluted tubule, respectively.

188 Henle, the intercalated cells of the distal convoluted tubule, the connecting segment, and all inter

189 tive region of the nephron, i.e., the distal convoluted tubule, the connecting tubule, and the cortic

190 Henle, the Na-Cl cotransporter of the distal convoluted tubule, the epithelial Na+ channel of the col

191 rption across the S2 segment of the proximal convoluted tubule, transepithelial potential differences

192 use TRPV5 and Klotho coexpress in the distal convoluted tubule, we investigated whether Klotho regula

193 the dissociation can be traced to the distal convoluted tubule, where calcium and sodium transport ar

194 P receptor is highly expressed in the distal convoluted tubule, where it may have a distinct effect o

195 uitous kinase isoform of WNK1, in the distal convoluted tubule, which in turn, stimulates the activit

196 in with predominant expression in the distal convoluted tubule.

197 e sites in vivo, predominantly in the distal convoluted tubule.

198 thick ascending limb, but also by the distal convoluted tubule.

199 trate must pass before reaching the proximal convoluted tubule.

200 enhanced WNK pathway activity in the distal convoluted tubule.

201 ria, and morphological changes in the distal convoluted tubule.

202 n of Bowman's space and the initial proximal convoluted tubule.

203 imal tubule, thick ascending limb, or distal convoluted tubule.

204 or salt reabsorption in the mammalian distal convoluted tubule.

205 timulate transport in the TAL and the distal convoluted tubule.

206 e, whereas it is transcellular in the distal convoluted tubule.

207 protein produced predominantly in the distal convoluted tubule.

208 ng limb of the loop of Henle, and the distal convoluted tubule.

209 in mDCT15 cells, a model of the mouse distal convoluted tubule.

210 Following microinjection into distal convoluted tubules (DCTs) 46.1 +/- 6.1 % (n = 8) of the

211 ascending limb of Henle (TAL) and in distal convoluted tubules (DCTs): Ksp-cre;Pth1r(fl/fl) Mutant m

212 rved between the development of the granular convoluted tubules (GCT) of the SMG in these mice and SM

213 Following microinjection into proximal convoluted tubules (PCTs), 18.5 +/- 2.9 % (mean +/- s.e.

214 nating in widespread destruction of proximal convoluted tubules at the glomerulotubular junction.

215 infection, epithelial cells of the proximal convoluted tubules frequently contained abnormal mitocho

216 a strong decrease in NCC labeling in distal convoluted tubules of aldosterone-escape rats with no ch

217 hy (OCT) revealed that cells lining proximal convoluted tubules of living donor kidneys (LDKs) procur

218 Kidney expresses RALDH2 in the proximal convoluted tubules of the cortex but not in the distal c

219 protein primarily in the proximal and distal convoluted tubules of the cortex but not in the glomerul

220 ne of transporting epithelia in the proximal convoluted tubules of the kidney and the small intestine

221 lication and gene expression in the proximal convoluted tubules of the kidney by causing interstitial

222 lial cells of the mammary glands; (e) distal convoluted tubules of the kidney; (f) epidermal keratino

223 hate co-transporter NaPi-IIa in the proximal convoluted tubules of the outer renal cortex, assessed b

224 Segments of superficial proximal convoluted tubules or cysts, isolated by upstream and do

225 tubules of the cortex but not in the distal convoluted tubules or glomeruli.

226 6) M angiotensin II to the lumen of proximal convoluted tubules perfused in vivo had no effect on the

227 The transport of organic anions in proximal convoluted tubules plays an essential role in the active

228 Fractional water reabsorption in proximal convoluted tubules was enhanced in potassium-depleted ra

229 tion studies showed that developing proximal convoluted tubules were the most severely hypoxic nephro

230 l nephron structures (podocytes and proximal convoluted tubules) despite the presence of activated No

231 l cells in the thick ascending limbs, distal convoluted tubules, and collecting ducts of mice.

232 d absorption are sharply reduced in proximal convoluted tubules, blood pressure is reduced and there

233 in the extracellular matrix surrounding the convoluted tubules, collecting ducts and loops of Henle

234 by reduced levels of TRPV5 protein in distal convoluted tubules, with a concomitant increase in TRPV5

235 basement membrane thickening in the proximal convoluted tubules.

236 RNA was markedly increased in renal proximal convoluted tubules.

237 with a putative cell of origin in the distal convoluted tubules.

238 ricted to the epithelium of the renal distal convoluted tubules.

239 d tubular atrophy particularly in the distal convoluted tubules.

240 ression in kidney was restricted to proximal convoluted tubules; little or no expression was observed

241 show the formation and evolution of a highly convoluted turbulent flame in the gravitational field of

242 s neurexin and scribble, but that nervana 2, convoluted, varicose, and cystic have functions not shar

243 lvent penetration into the protein, possibly convoluted with melting of hydrated helix segments.

244 t mimic cell topography, but are rather more convoluted, with a higher respiration activity observed