ライフサイエンスコーパス: core protein

1 ing of the mu subunit of AP-2, AP2M1, to HCV core protein.

2 n with the distinct quaternary structures of core protein.

3 re of an antiviral compound bound to the HBV core protein.

4 ressed in cells replicating DHBV with the WT core protein.

5 unction, which is exerted likely via the BGN core protein.

6 sis from A36V mutant than from the wild-type core protein.

7 ated sequence contiguous with the linkage to core protein.

8 in the alpha-helical structure of the TILRR core protein.

9 re enzymatically degraded or absent from the core protein.

10 signaling by mediating Wnt function via its core protein.

11 of the core gene, adding 12 residues to the core protein.

12 and affected nuclear localization of the HBV core protein.

13 ry domain contained within its extracellular core protein.

14 with the C-terminal arginine-rich domains of core protein.

15 n experimental class of antivirals that bind core protein.

16 FRRS1L, which encodes an AMPA receptor outer-core protein.

17 an enrichment filter were utilized to define core proteins.

18 SII core complexes and co-immunoprecipitates core proteins.

19 on, and light vulnerability of photosystem I core proteins.

20 sites possibly masked in the virus by other core proteins.

21 eaction by bridging the L7Ae and fibrillarin core proteins.

22 complexes are each assembled with three sRNP core proteins.

23 proteolytic processing of several capsid and core proteins.

24 cosaminoglycan (GAG) chains attached to CSPG core proteins.

25 the hexon, penton, fiber, minor capsid, and core proteins.

26 ncreased amounts of unprocessed membrane and core proteins.

27 rates of antibodies against the hepatitis B core protein (0.99% and 1.88%; P = .19) and HBsAg (0.14%

28 lex containing five assembly factors and two core proteins, 15.5K and Nop58; (b) the characterization

29 itive for antibodies against the hepatitis B core protein (16.76%) and HBsAg (9.26%) than children wi

30 ix protein, ubiquinol-cytochrome c reductase core protein 2 or the inner mitochondrial membrane prote

31 ation on the EGF-like repeat of the versican core protein, a proposed substrate of Fringe beta-1,3-N-

32 ray is a hexagonal lattice formed from three core proteins: a transmembrane receptor, the His kinase

33 large set of peptides derived from the major core protein A10L and other known vaccinia epitopes boun

34 ells infected with VACV expressing the viral core protein A4 fused to yellow fluorescent protein.

35 Yeast two-hybrid experiments identified PG core proteins ABC1K3, PES1, and CCD4 as PGM48 interactor

36 Several baculovirus conserved (core) proteins (Ac76, Ac78, GP41, Ac93, and Ac103) that

37 ase product is dispensable for LON-2 minimal core protein activity, it does affect the localization o

38 N-2 N-terminal domain is necessary for LON-2 core protein activity, suggesting that LON-2 inhibits BM

39 Core protein allosteric modulators (CpAMs) are an experi

40 Small molecules that target core protein (core protein allosteric modulators [CpAMs]) represent a

41 ith cell culture-grown HCV or expressing HCV core protein also displayed significant repression of C9

42 f collagen molecules among themselves and PG core proteins among themselves, together with limited li

43 Ft-Ds-Fj-mediated cues are weak and that the core proteins amplify them.

44 e, we identify HSPGs containing a glypican 5 core protein and 2-O-sulfo-iduronic acid residues at the

45 ssion of HBV surface antigen (HBsAg) and the core protein and enhanced viral replication.

46 aracterized protein that is a PSII auxiliary core protein and hence is named PHOTOSYSTEM II PROTEIN33

47 aracterized an interaction between the viral core protein and host protein within bgcn homolog (WIBG)

48 hains, syndecan-4 binding relies on both its core protein and its heparan sulfate chains.

49 rboxyl-terminal domain (CTD) of hepadnavirus core protein and its state of phosphorylation are critic

50 s (LDs) and facilitates its interaction with core protein and the viral assembly.

51 ith this, GPC6 interacts with Hh through its core protein and with Ptc1 through its glycosaminoglycan

52 nomes are normalized for diversity with 1867 core proteins and a paralog-collapsed pan-genome size of

53 Loss-of-function mutations in glypican core proteins and in glycosaminoglycan-synthesizing enzy

54 h a specific proteome of approximately 30 PG core proteins and isoprenoid and neutral lipids.

55 that can infect cells and express the viral core proteins and neuraminidase but cannot replicate.

56 n invertebrates, however, knowledge of CSPGs core proteins and proteoglycan-related functions is rela

57 is necessary for the stabilization of snoRNP core proteins and target of rapamycin activity and likel

58 pressed, proteolytic processing of the major core proteins and the A17 protein, which is an essential

59 Although many of the genes that encode HSPG core proteins and the biosynthetic enzymes that generate

60 Two pathways regulate planar polarity: the core proteins and the Fat-Dachsous-Four-jointed (Ft-Ds-F

61 hree cohorts for binding to a panel of gp120 core proteins and their corresponding CD4bs knockout mut

62 hesizing enzymes have revealed that glypican core proteins and their glycosaminoglycan chains are imp

63 o chromosomes, whereas Mip130 (Lin9) (an MMB core protein) and E2f2 (an MMB transcriptional repressor

64 Here, we show that the core proteins are preferentially distributed to discrete

65 oteins to junctions, whereas the cytoplasmic core proteins are required for their concentration into

66 roteins redistribute and colocalize with HCV core protein around lipid droplets (LDs).

67 a core protein as serglycin, (ii) the 90-kDa core protein as inter-alpha-inhibitor heavy chain 2 (Ial

68 mass spectrometry identified (i) the 25-kDa core protein as serglycin, (ii) the 90-kDa core protein

69 Recombinantly expressed core protein assembles into T=3 and T=4 icosahedral shel

70 gnized CpAM activity is that they accelerate core protein assembly and strengthen interactions betwee

71 It is anticipated that small molecular core protein assembly modulators may disrupt one or mult

72 structure of N-glycosylated human glypican-1 core protein at 2.5 A, the first crystal structure of a

73 ermore, hepsin directly cleaved the aggrecan core protein at a novel cleavage site within the intergl

74 ethods to determine the dynamics of eisosome core proteins at different subcellular locations.

75 apsids through specific interaction with HBV core protein but not other viral and host cellular compo

76 MRB1 consists of six core proteins but makes dynamic interactions with additi

77 large viroplasm inclusions containing virion core proteins but no viral membranes.

78 We report that the clearance of the core protein by the tissue plasminogen activator (tPA)/p

79 uced a protocol to characterize proteoglycan core proteins by identifying CS-glycopeptides with a com

80 on and dephosphorylation of the hepadnavirus core protein C-terminal domain (CTD) are required for mu

81 Phosphorylation of the hepadnavirus core protein C-terminal domain (CTD) is important for vi

82 on in regulons and cascades and describe how core protein circuits and cis-regulatory sequences in pr

83 four times more alternative nucleotides than core protein-coding regions that diversify exclusively v

84 osections revealed that the HCV envelope and core proteins colocalize with apolipoproteins and HCV RN

85 verse range of macromolecules, including the core protein components, the cytoplasmic lipid membrane,

86 uses cross-reacted with sera against the HBV core protein, concordant with the phylogenetic relatedne

87 Glypican core proteins consist of a stable alpha-helical domain c

88 Small molecules that target core protein (core protein allosteric modulators [CpAMs]

89 g other biosynthetic enzymes or proteoglycan core proteins could not account for the observed changes

90 ther, these results for C9 regulation by HCV core protein coupled with functional impairment of the m

91 The majority of the core protein (CP149) comprises the capsid assembly domai

92 ld-type core protein (Cp183-WT) and a mutant core protein (Cp183-EEE), in which three CTD serines are

93 We examined wild-type core protein (Cp183-WT) and a mutant core protein (Cp183

94 So far, only nine core proteins (CPGs) have been identified, some of which

95 (DHBc) was observed when the WT and most HBV core protein CTD (HCTD) variants were coexpressed in tra

96 V-B acclimation preserved the photosystem II core proteins D1 and D2 under UV-B stress, which mitigat

97 rs that may interact differentially with the core protein depending on its CTD phosphorylation state,

98 idues in the hydrophobic base of the capsid (core) proteins, designated motifs I, II, and III, are hi

99 atic decrease in phosphorylation of the DHBV core protein (DHBc) was observed when the WT and most HB

100 roaryldihydropyrimidine (HAP) pocket between core protein dimer-dimer interfaces.

101 riptional DNA replication to take place, the core protein dimers, existing in several different quate

102 n the pre-genomic RNA with high affinity for core protein dimers.

103 Further analysis suggested that HCV core protein displayed a weak repression of C3 promoter

104 CV-infected individuals and treated with HCV core protein displayed increased PD-1 and SOCS-1 express

105 The analysis of the core protein domain organization revealed that all chond

106 gh mechanisms largely thought to exclude the core protein domain.

107 virus (HBV) or duck hepatitis B virus (DHBV) core protein, either the wild type (WT) or with alanine

108 rus (DHBV) and human hepatitis B virus (HBV) core protein, either with wild type (WT) sequences or wi

109 rker and a fluorescently tagged Vpr (a viral core protein) enables detection of single-virus fusions,

110 The hepatitis B virus (HBV) Core protein encodes a late (L)-domain like motif (129PP

111 mb Repressive Complex 2 (PRC2) contains four core proteins, Enhancer of Zeste (E(z)), Suppressor of Z

112 tion provided an "anchor" for the Abs as the core protein epitope varies, prevented complete neutrali

113 ing T cells to the pH1N1 virus and conserved core protein epitopes with clinical outcomes after incid

114 Beclin-1 (also known as Atg6 in yeast) is a core protein essential for autophagic initiation and oth

115 ng studies in C. elegans identified a set of core proteins essential for centriole duplication [6-12]

116 In this study, we report that HCV core protein, expressed in Huh7 and Madin-Darby canine k

117 HCV infection or core protein expression alone in transfected Huh7.5 cell

118 he insertion is needed to maintain efficient core protein expression and genome replication but cause

119 t the 36-nt insertion had similar effects on core protein expression and virion secretion when it was

120 Further, HCV infection or core protein expression in Huh7.5 cells significantly de

121 virus (HCV) infection of hepatocytes or HCV core protein expression in transfected hepatocytes upreg

122 t hepatitis C virus (HCV) infection or virus core protein expression upregulates CD55 expression.

123 Cas4 proteins, a core protein family associated with the microbial system

124 we have investigated the turnover of two key core proteins, Flamingo and Frizzled, and find that the

125 Furthermore, the transmembrane core proteins, Flamingo, Frizzled, and Strabismus, are n

126 tifies other catalysts that contain a shared core protein fold but whose active sites are located in

127 Cullin3 (CUL3), a core protein for the CUL3-RING ubiquitin ligase complex,

128 tivity, attractant regulation, and its bound core proteins for days or more at 22 degrees C.

129 In addition, RFUVA cross-links PG core proteins, forming higher molecular weight polymers.

130 Hepatitis C virus core protein forms the viral nucleocapsid and plays a cr

131 E2 binds at the dimer-dimer interface of the core proteins, forms a new interaction surface promoting

132 Focusing on the key core protein Frizzled, we show that its stable junctiona

133 Here we investigate core protein function during planar polarization of the

134 w the CTD phosphorylation state may modulate core protein functions but phosphorylation state-depende

135 fate determination, in vivo knockdown of PCP core proteins FZD3 and CELSR1-3 revealed severe maturati

136 perinatally lethal mutation in the aggrecan core protein gene, cmd(bc) (Acan(cmd-Bc)), that deletes

137 Hepatitis B virus core protein has 183 amino acids divided into an assembl

138 The HCV core protein has been shown to directly interact with an

139 The syndecan-1 core protein has multiple domains that confer distinct c

140 Hepatitis B virus core protein has multiple roles in the viral life cycle-

141 55) epitopes of EV71 using hepatitis B virus core protein (HBc) as a carrier, designated HBc-E1/2.

142 iple subunits of the hepatitis B virus (HBV) core protein (HBc) assemble into an icosahedral capsid t

143 enesis were employed to demonstrate that HBV core protein (HBc) is a PLK1 substrate.

144 Whereas the hepatitis B core protein (HBc) VLP appears to be the most promising

145 HBV core protein (HBc), encoded by the HBV genome, may play

146 of multiple copies of a single protein, the core protein (HBc).

147 In contrast to MHBs, a VLV expressing HBV core protein (HBcAg) neither induced a CD8 T cell respon

148 A crude Hepatitis B virus core protein (HBcAg) was separated using polyacrylamide

149 ination did not induce antibodies to the HBV core protein (HBcore), the standard biomarker for HBV in

150 We have reported that HCV core protein (HCVc) manipulates human blood-derived dend

151 alation during CE is regulated by a group of core proteins identified originally in flies to coordina

152 The IFT-B core proteins IFT74 and IFT81 interact directly through

153 gomerization properties of hepatitis B virus core protein illustrate both the importance of C-termina

154 We previously demonstrated that HCV core protein impairs IL-12 expression by monocytes/macro

155 uring infection or ectopic expression of HCV core protein.IMPORTANCE Endoglin plays a crucial role in

156 east cancer susceptibility gene 1 (Brca1), a core protein in DNA-damage repair, was repressed by CtBP

157 inase ABC treatment that removes CS from its core protein in the chondroitin sulfate proteoglycans or

158 ent study, we have profiled each of the HSPG core proteins in HCV attachment.

159 ttachment protein receptors (SNAREs) are the core proteins in membrane fusion.

160 o measure the binding of mRNA export and EJC core proteins in nuclear complexes.

161 n system using purified, non-glycosylated PG core proteins in solution in vitro has been compared wit

162 us, we define the distinct roles of specific core proteins in the formation of asymmetric contacts be

163 NV MR system for functional analysis of SYNV core proteins in trans and the cis-acting leader and tra

164 ities required expression of the N, P, and L core proteins in trans and were enhanced by codelivery o

165 psid particle p24) or HCV (hepatitis C virus core protein) in transplastomic tobacco.

166 The HSPG core proteins include the membrane-spanning syndecans (S

167 combinant biglycan proteoglycan and biglycan core protein increased Wnt-induced beta-catenin/T cell-s

168 st abundant envelope protein, VP24 acts as a core protein interacting with other structure proteins a

169 egies against ATP6AP2, a recently discovered core protein involved in both signaling pathways, reveal

170 is a bacterial actin homolog and one of the core proteins involved in cell division.

171 Hence, HBV core protein is a dominant antiviral target that may sup

172 Though the hepatitis B virus (HBV) core protein is an important participant in many aspects

173 rboxyl-terminal domain (CTD) of hepadnavirus core protein is critical for viral replication.

174 in pNS3h that rescue viruses from which the core protein is deleted map to D3, suggesting that this

175 The hepatitis B virus (HBV) core protein is essential for HBV replication and an imp

176 The C-terminal domain (CTD) of hepadnavirus core protein is involved in multiple steps of viral repl

177 The Dlp core protein is required for normal responsiveness to He

178 Accumulation of PSII core proteins is compromised under these conditions in t

179 subcellular asymmetries of Ft and Ds and the core proteins is largely independent in the wing disc an

180 fies the virion to release the viral RNA and core proteins is not well understood.

181 This asymmetric distribution of the core proteins is proposed to require amplification of an

182 In contrast, VP3, the other major structural core protein, is an essential component of the complex,

183 residue G33, located within domain 1 of the core protein, is important for the production of cell cu

184 roitin sulfate (CS) chain of bikunin, or the core protein itself, enables the bikunin proteoglycan (P

185 stals of selenomethionine-labeled glypican-1 core protein lacking the HS domain.

186 When junctional core protein levels are either increased or decreased by

187 Loss of asymmetry by altered core protein levels can be explained by reference to fee

188 s through more than one mechanism to control core protein levels in Drosophila, and that without this

189 ymmetry appears to require the regulation of core protein levels, but the importance of such regulati

190 T decreases HBV replication and HBV mRNA and core protein levels.

191 , but recent reports have suggested that the core protein mammalian telomerase reverse transcriptase

192 t statistically significant levels, with the Core protein may drive virion assembly.

193 he membrane lytic protein VI molecules, this core protein may serve as a bridge from the inner dsDNA

194 We show that these core proteins may have a role in intra-cellular communic

195 nding site on the CD55 promoter impaired HCV core protein-mediated upregulation of CD55.

196 The archaeal Nop56/58 core protein mediates crucial protein-protein interactio

197 We have recently shown that HCV core protein mediates functional inactivation of the pro

198 glypican-1, not syndecan-1, is the dominant core protein mediating shear-induced NO production.

199 The impact of naturally occurring core protein mutations on antiviral activity correlates

200 3.6 A resolution with atomic models for ten core proteins, nearly all essential domains of its RNA,

201 ) built on the Newcastle disease virus (NDV) core proteins, NP and M, and containing two chimeric pro

202 containing the Newcastle disease virus (NDV) core proteins, NP and M, and two chimera proteins (F/F a

203 It is also a core protein of cholesterol gallstones.

204 Mutations at positions 70 and/or 91 in the core protein of genotype-1b, hepatitis C virus (HCV) are

205 he structural and functional analysis of the core protein of hepatitis B virus is important for a ful

206 The core protein of perlecan was an exclusive component of t

207 he low intracellular levels of viral DNA and core protein of wild-type genotype C delay immune cleara

208 s may provide a new method of evaluating the core proteins of an organism.

209 g domain of chemoreceptors and are among the core proteins of chemosensory cascades.

210 Both the sugar chains and core proteins of chondroitin sulfate proteoglycans (CSPG

211 ed on "synthetic" viruses in which the outer core proteins of different BTV serotypes are incorporate

212 ns keratocan, lumican, mimecan, and decorin, core proteins of major proteoglycans (PGs) that bind col

213 he levels of cyt f (PetA) and cyt b6 (PetB), core proteins of the cyt b6f complex.

214 mixed lineage kinase domain like (MLKL), two core proteins of the necroptosis pathway, blocks crystal

215 HBc, the capsid-forming "core protein" of human hepatitis B virus (HBV), is a mul

216 Further analysis suggested that the HCV core protein or full-length (FL) genome enhanced CD55 pr

217 th packaging of the pgRNA and P protein into core protein particles, followed by conversion of RNA in

218 ize, and encompass thousands of units of the core proteins Pil1 and Lsp1.

219 and virus-induced mechanisms, with the viral core protein playing an important role in steatosis deve

220 Further analyses indicated that HCV core protein plays a significant role in modulating the

221 antiviral agents against HBV.IMPORTANCE HBV core protein plays essential roles in many steps of the

222 ed to interaction of the chromodomain of the core protein Polycomb with trimethyl histone H3K27 (H3K2

223 The absence of planar cell polarity (PCP) core proteins Prickle1 and Prickle2 in individual cells

224 except for the absence of A19 and decreased core protein processing, they appeared to have a similar

225 Sequencing of the avian poxvirus 4b core protein produced an identical viral sequence from e

226 rVN specifically bound to authentic versican core protein produced by dermal fibroblasts.

227 fation of the CS chain of bikunin and/or its core protein promote HC transfer by TSG-6 to its relativ

228 d only two polypeptides: the reaction center core protein PscA and a 22-kDa carotenoid-binding protei

229 mount of heparan sulfate present on syndecan core proteins regulates both the rate of syndecan sheddi

230 ide triphosphate phosphohydrolase I, and two core proteins required for morphogenesis.

231 lizing and destabilizing interactions of the core proteins required for self-organization of planar p

232 smodium falciparum identified genes encoding core proteins required for the homologous recombination

233 he maturation of the hepatitis C virus (HCV) core protein requires proteolytic processing by two host

234 TGN membranes to closely associate with HCV core protein residing on lipid droplets.

235 that loss of HS biosynthesis or of the SDN-1 core protein results in misorientation of the spindle of

236 The crystal structure of the decorin core protein revealed a tight dimer formed by the associ

237 These core protein-RNA contacts may play one or more roles in

238 The system is composed of core proteins SecA2 and SecY2 and accessory Sec proteins

239 The interaction of DDX3X with HCV core protein seems to be dispensable for its proviral ro

240 ies yield insight into the interplay between core protein self-assembly and the host environment, whi

241 nique internal feature connected to the main core protein shell via lobes of density.

242 Yet many of its core proteins show evidence of rapid or adaptive evoluti

243 The ESCRT-III core protein Shrub has a central role in endosome-to-mul

244 Further studies suggested that HCV core protein significantly upregulates c-Kit expression

245 Mapping studies using gp120 core protein, single-residue knockout mutants, and chime

246 -rich C-terminal tail of the essential snRNP core proteins SmN/B/B'.

247 experiments and the crystal structure of the core protein Snu13p/15.5K bound to a fragment of the ass

248 e junctional localization is promoted by the core proteins Strabismus, Dishevelled, Prickle, and Dieg

249 at the postenvelopment step and that the HCV Core protein strongly associates with the DRM, recruitme

250 f the helix-loop-helix motif observed in the core protein structure (residues 15 to 41; Protein Data

251 typic diversity, generally do not affect the core protein structures and have no deleterious effect o

252 tatic, the other half is actively exchanging core protein subunits.

253 e heparan sulfate chains present on syndecan core proteins suppress shedding of the proteoglycan.

254 d with HCV-infected hepatocytes, or with HCV core protein, suppress autologous T-cell responses.

255 sized that marked shedding of the glycocalyx core protein, syndecan-1, occurs in end-stage liver dise

256 s, which exhibited a marked depletion of HBV core protein synthesis and down-regulation of pre-genomi

257 lates both the rate of syndecan shedding and core protein synthesis.

258 ate is accompanied by a dramatic increase in core protein synthesis.

259 e selection of drug-resistant viruses during core protein-targeting antiviral therapy.

260 The discovery of novel core protein-targeting antivirals, such as benzamide der

261 protein VII, a virally encoded histone-like core protein that is suggested to protect incoming viral

262 Here we describe how a small adenovirus core protein that localizes to host chromatin during inf

263 fied the necessary domains of the syndecan-1 core protein that modulate its function in lung epitheli

264 een the viral pre-genome and the hepatitis B core protein that play roles in defining the nucleocapsi

265 structural proteins and composed of several core proteins that closely interact with the packaged ds

266 tion plus phylogenetic analyses of conserved core proteins that have just 20% to 50% or less identity

267 he shared, chaperone-bound scaffold of H/ACA core proteins that mediates initial RNP assembly.

268 we designed a structural mimic of AEf-bound core protein, the V124W mutant.

269 substantial decreases in the amounts of PSI core proteins, the content of 3Fe-4S-containing ferredox

270 driven by feedback interactions between the core proteins themselves.

271 lls replicating the virus with the wild-type core protein to determine the roles of CTD in viral repl

272 tating the core gene Kozak sequence restored core protein to lower levels but increased replication o

273 n sulfate enhances the susceptibility of the core protein to proteolytic cleavage by matrix metallopr

274 that heparan sulfate must be attached to the core protein to suppress shedding.

275 ns and the C-terminal domain that attach the core protein to the cell membrane are not resolved in th

276 HS is known to covalently attach to core proteins to form heparan sulfate proteoglycans (HSP

277 us, are necessary for stable localization of core proteins to junctions, whereas the cytoplasmic core

278 RNPs) involves the sequential recruitment of core proteins to snoRNAs.

279 HCV-infected or core protein-transfected Huh7.5 cells displayed greater

280 assays suggest that increased efficiency of core protein translation diminishes ribosomal scanning t

281 hly flexible in solution, but it orients the core protein transverse to the membrane, directing a sur

282 e, and unveil its associations with VIII and core protein V, which together glue peripentonal hexons

283 nctions of the maternal planar cell polarity core protein Vangl2 and the apical-basal complex compone

284 ng viral genome from checkpoint signaling by core protein VII and suggest that the induction of an MR

285 onds to the recognition of the viral genome, core protein VII binding to and checkpoint signaling at

286 mporal correlation between the loss of viral core protein VII from the adenovirus genome and a gain o

287 e composed of a symmetrical capsid (built of core protein), viral pregenomic RNA, and viral reverse t

288 ined by immunohistochemical detection of the core protein VP1 of HPyV-6.

289 RNA, the viral polymerase VP1, and the inner core protein VP2.

290 rms the carboxy-terminal domain of the minor core protein VP3 (VP3-CTD) and shares sequence and predi

291 CSC generation by HCV core protein was dependent on the endoglin signaling pat

292 ic capsids from wild-type and drug-resistant core proteins was susceptible to multiple capsid assembl

293 uences of the assembly domain of WHV and HBV core proteins (wCp149 and hCp149, respectively) have 65%

294 m phage libraries and streptavidin/avidin as core protein were used for direct detection of small com

295 A total of 124 and 42 core proteins were identified in betaC-plastoglobuli and

296 f triacsin C, reduced stability of the viral core protein, which forms the virion nucleocapsid and is

297 ival; it is composed of 12 mostly multimeric core proteins, which build a sophisticated secretion mac

298 link the anti-lipolytic activity of the HCV core protein with altered ATGL binding to CGI-58 and the

299 The exon junction complex core protein Y14 is required for nonsense-mediated mRNA

300 22, we found that eIF4AIII and the other EJC core proteins Y14 and MAGO bind the nascent transcripts