ライフサイエンスコーパス: corneal staining

1 not the co-primary sign end point (inferior corneal staining).

2 ar break-up time (TBUT) and conjunctival and corneal staining.

3 inical signs and disease severity defined by corneal staining.

4 had repeated episodes of moderate or greater corneal staining.

5 tions nor disinfectants were associated with corneal staining.

6 Schirmer test (5.7 vs 15.3 mm, P < 0.0001), corneal staining (1.4 vs 0.2, P < 0.0001), conjunctival

7 dition, only a significant increase in nasal corneal staining (2.9 +/- 0.5 vs 3.6 +/- 0.5, P = .03) w

8 ients showing an increase 1 point or more in corneal staining and a reduction of 2 points or more (0-

9 The main exposures of interest were corneal staining and bacterial lens contamination.

10 -group differences on secondary signs: total corneal staining and nasal lissamine staining.

11 ligibility criteria included exacerbation in corneal staining and ocular symptoms with controlled adv

12 ls were used to examine the relation between corneal staining and these factors.

13 r film breakup time [TBUT], Schirmer I test, corneal staining), and tear osmolarity measurements, tog

14 e eye examination, tear film function tests, corneal staining, and Cochet-Bonnet esthesiometry were p

15 x [OSDI]), signs (tear break-up time [TBUT], corneal staining, and Schirmer's score), and clinical de

16 scus height, tear break-up time, fluorescein corneal staining) at 6 months within plug groups except

17 ere compared with tear break-up time (TBUT), corneal staining, conjunctival staining, and an irritati

18 the ocular surface disease index (OSDI) and corneal staining (CS), 95 DED patients (OSDI >/=13) with

19 Tear meniscus height correlated with corneal staining for all subjects (R = -0.32; P = .0008)

20 s had a significant (P </= .003) increase in corneal staining (from 0.68 +/- 0.15 to 1.16 +/- 0.14 an

21 associated with a significantly higher total corneal staining grade (beta, +0.9 for each additional g

22 The corneal staining grade was greater in glaucoma subjects

23 =210 mum, relative risk ratio for developing corneal staining >/=10 was 4.65.

24 cantly associated with TBUT, presence of any corneal staining in any corneal zones, or symptomatic st

25 Corneal staining in contact lens wearers continues to be

26 ent-related factors that are associated with corneal staining in contact lens wearers.

27 actors were shown to be related to increased corneal staining in multivariate modeling, including inc

28 a (1.3 +/- 0.1 vs 1.6 +/- 0.1, P = .05), and corneal staining in temporal (3.5 +/- 0.5 vs 4.7 +/- 0.4

29 Corneal staining is common during continuous wear of SH

30 e FML group showed no significant changes in corneal staining (mean, 0.86; 95% confidence interval [C

31 nt worsening (P</=0.009) in these variables (corneal staining: mean, 1.95; 95% CI, 1.57-2.33 vs. mean

32 t anesthesia, tear film breakup time (TBUT), corneal staining, meibomian dysfunction assessment, and

33 ely 53% of subjects had repeated episodes of corneal staining (mild or greater), and 11.3% had repeat

34 tear break-up time (s), inferior fluorescein corneal staining (National Eye Institute [NEI] scale), a

35 opposed to hydrogels) was protective against corneal staining (P = 0.0004).

36 001), conjunctival staining (P < 0.001), and corneal staining (P = 0.007).

37 with the global parameters conjunctival and corneal staining (r = 0.16) and TBUT (r = -0.15).

38 owed by conjunctival staining (r(2) = 0.47), corneal staining (r(2) = 0.43), OSDI (r(2) = 0.41), meib

39 anesthesia of less than 10 mm/5 minutes, and corneal staining results of 1 or more.

40 Corneal staining (right eye 0.86, 95% CI 0.76-0.93, left

41 e OSDI questionnaire, TBUT, conjunctival and corneal staining, Schirmer test results without anesthes

42 Tear film breakup time (TBUT), corneal staining score (0-15), and Schirmer's test resul

43 sign) was mean change from baseline inferior corneal staining score (ICSS) at day 84.

44 A dose response for the corneal staining score (P = .0566) was observed for SAR

45 Primary outcome measure was inferior corneal staining score at day 84.

46 study eye, eye discomfort score (VAS), total corneal staining score in the study eye, and nasal conju

47 showed significant improvements (P < .05) in corneal staining score, total OSDI, and visual-related f

48 glaucoma therapy burden seems predictive of corneal staining severity.

49 clinical examination (i.e., tear osmolarity, corneal staining, tear breakup time, Schirmer's, meibomi

50 position) are more generally associated with corneal staining than are contact lens care solutions or

51 For corneal staining (total score), significant improvement

52 was no between-group difference in inferior corneal staining (treatment effect, 0.03; 95% CI, -0.10

53 Corneal staining was not associated with the development

54 atients having a 1-grade or more increase in corneal staining was significantly (P = 0.03) higher in

55 After 3 days, saline-injected mice showed no corneal staining, whereas BTX-B-injected mice displayed

56 trol study, in addition to the assessment of corneal staining with fluorescein, a variety of tear fil

57 Surface Disease Index (OSDI) questionnaire, corneal staining with fluorescein, conjunctival staining