ライフサイエンスコーパス: corona

1 ona") as well as physisorbed proteins ("soft corona").

2 oteins forming what is known as the protein 'corona'.

3 Rosuvastatin Multinational Trial in HF-REF (CORONA).

4 statin Multinational Trial in Heart Failure (CORONA).

5 lease of magnetic energy stored in the Sun's corona.

6 the chemical composition of the SNA protein corona.

7 g a continuous layer visually appearing as a corona.

8 nostics for their presence in the nonflaring corona.

9 ydrophobic PPS core and PNIPAAM on the outer corona.

10 fic proteins that form the so-called protein corona.

11 ionic PGlu intermediate shell layer, and PEG corona.

12 ers with a 5kgmol(-1) methoxy-terminated PEG corona.

13 nsivity is endowed by a responsive polymeric corona.

14 % mannoside-terminated PEG chains in the PEG corona.

15 mechanisms in the Sun's outer atmosphere, or corona.

16 he inhomogeneous magnetic field of the solar corona.

17 ic particles akin to those seen in the solar corona.

18 the chromosphere but not, until now, in the corona.

19 a densely functionalized aptamer-displaying corona.

20 rresponding to radio wave propagation in the corona.

21 long the Sun's magnetic field lines into the corona.

22 erate the fast solar wind and heat the quiet corona.

23 or balance the radiative losses of the quiet corona.

24 the interface region between photosphere and corona.

25 is wave mode is sufficient to heat the solar corona.

26 of 50 to 150 kilometers per second into the corona.

27 - 12 gauss magnetic field measurement in the corona.

28 d size because of the formation of a protein corona.

29 metric poly(3-hexylthiophene) or polystyrene corona.

30 ) W m(-2)) is transferred onto the overlying corona.

31 iarm stars with boronic ester cores and PDMA coronas.

32 robrain natriuretic peptide (hazard ratio in CORONA, 1.50; 95% confidence interval, 1.17-1.92; P=0.00

33 ecreasing galectin-3 levels (hazard ratio in CORONA, 1.60; 95% confidence interval, 1.13-2.25; P=0.00

34 bsorb proteins to form 'nanoparticle-protein coronas', a process governed by molecular interactions b

35 arrier, and a densely packed alendronic acid corona acting as a stabilizer and targeting moiety.

36 planation for the composition of the protein corona, aiding in the development of safe and effective

37 The protein corona alters the size and interfacial composition of a

38 e-art magnetohydrodynamic model of the solar corona and a model for the motion of emitting cometary t

39 er issues such as the formation of a protein corona and antibody multivalency interfere with the labe

40 to play a role in heating the million-degree corona and are associated with Alfvenic waves that help

41 boratories, Earth's magnetosphere, the solar corona and astrophysical environments.

42 gineering of hollow structures with suitable corona and canopy species.

43 s known about the atomistic structure of the corona and how it influences the phase behavior and prop

44 ausing energy exchange between the Sun's hot corona and its cool lower atmosphere remain poorly under

45 stigation of the temporal profile of protein corona and its evolution in biological matrices as well

46 The detailed morphology of the subgiant's corona and its possible interaction with its companion a

47 with lower HLB value, less dense hydrophilic corona and more hydrophobic core volume are efficient in

48 aining blocks with a homogeneous polystyrene corona and those with a patch-like polystyrene/poly(meth

49 ion region (between the chromosphere and the corona) and of the corona that reveal how Alfvenic motio

50 statin in Multinational Trial Heart Failure (CORONA) and the Gruppo Italiano per lo Studio della Sopr

51 old nanoparticle system packaged with a SipA corona, and found this bacterial mimic not only accumula

52 al gold nanoplasmonics, nanoparticle-protein corona, and nanoparticle-membrane interaction.

53 against HPV infection of the urethra, glans/corona, and penile shaft.

54 active sequences displayed from the particle corona, and the ability to easily encapsulate biologics

55 f NMs dictate the composition of the protein corona, and the toxicity of NMs and iv) NMs can affect s

56 in (44%) was comparable to that in the glans/corona, and type-specific positivity was observed betwee

57 f species-specific formation of biomolecular coronas, and this suggests that the use of representativ

58 The seemingly inevitable protein corona appears to be an insurmountable obstacle to wider

59 is concluded that, regardless of the type of corona applied, CF(2)Br(2) reacts in air NTP via a commo

60 cell association, but effects on the protein corona are usually not considered.

61 Cells recognize the biomolecular corona around a nanoparticle, but the biological identit

62 se To evaluate if the formation of a protein corona around ferumoxytol nanoparticles can facilitate s

63 Conclusion The protein corona around ferumoxytol nanoparticles can facilitate s

64 ave profiled proteins forming the long-lived corona around silver nanoparticles (75 nm OECD reference

65 ntal data suggests that the microgels form a corona around the microspheres and induce a soft repulsi

66 in the absence of A17, small vesicles form a corona around the virosomes.

67 a) chitosan nanoparticles, while it formed a corona around those composed of more densely cross-linke

68 We demonstrate changes in protein coronas around these particles within biological media,

69 e used to detect chemisorbed proteins ("hard corona") as well as physisorbed proteins ("soft corona")

70 Though the onset of corona, as detected by the appearance of light, was alwa

71 served wave energy that is able to reach the corona based on observational constraints, which has imp

72 ofiles and to mechanistically understand the coronas' biological/ecological impact, we present a tier

73 sted of a N-(2-hydroxypropyl) methacrylamide corona block with pendent pyridyl disulfide groups for r

74 , relatively straight branch with a streamer corona burst at its far end.

75 ufficient Poynting flux not only to heat the corona but also to originate the supersonic solar wind.

76 d not only to highlight the presence of this corona, but also to estimate its apparent thickness to a

77 oxide NPs that were surrounded by a protein corona, can cross plasma membranes.

78 L1) and coronal steric effects (via the PtBA corona chain length in the P segment, L2 related to the

79 namely coronal steric effects (via the PtBA corona chain) and attractive interaction strength (via t

80 PFS cylinders with a residual percentage of corona chains dependent on the photoirradiation time.

81 nanoparticles (NPs) that dictate the protein corona characteristics.

82 In-depth NP protein corona characterization is therefore a necessary step in

83 icelles with variable and spatially distinct corona chemistries, including amphiphilic nanostructures

84 ecific interactions between the nanoparticle-corona complex and the cell surface including triggering

85 aphene surface quickly and tightly to form a corona complex.

86 ation of the nanoparticles was observed with corona complexes preformed of EfCP (p < 0.05).

87 nt role in the formation of protein-graphene corona complexes.

88 es that vary according to delivery route and corona composition following exposure.

89 his study explores the importance of protein corona composition for nanoparticle recognition by coelo

90 and the fibre length, and is independent of corona composition.

91 The cationic corona conferred CBLG with superior integrity and drug r

92 Patchy block copolymer micelles with a corona consisting of two chemically different patches ha

93 This is surrounded by a disordered corona containing the surfactant headgroups, counterions

94 ischemic systolic heart failure enrolled in CORONA (Controlled Rosuvastatin Multinational Study in H

95 ardiac dysfunction and prognosis measured in CORONA (Controlled Rosuvastatin Multinational Trial in H

96 nt of Reduction in Mortality and Morbidity], CORONA [Controlled Rosuvastatin Multinational Trial in H

97 shown that the formation of protein-graphene corona could effectively reduce its cytotoxicity; howeve

98 -coil BCPs in solution and selective micelle corona cross-linking, we have created short (about 130 n

99 e length using a strategy that also involved corona cross-linking.

100 The structure and composition of the protein corona depends on the synthetic identity of the nanomate

101 sequently, we will discuss about the protein corona derived from blood with foci on the physiochemica

102 o reliably and easily estimate the detergent corona diameter and select the smallest size, critical f

103 Ionization mechanisms, including corona discharge and electrospray, are involved in the i

104 The corona discharge atmospheric pressure chemical ionizatio

105 signment of oxidation artifacts formed under corona discharge conditions.

106 of a solid needle which is commonly used for corona discharge creation, helping us to have direct axi

107 plied on the carbon fiber bundle to initiate corona discharge for ionization of analytes.

108 We have successfully reduced corona discharge in negative ion mode by trace addition

109 We demonstrate the application of corona discharge ion mobility spectrometry with orthogon

110 th reactant ions on the upstream side of the corona discharge ionization source.

111 A corona discharge ionization-ion mobility spectrometry (C

112 Under high aqueous solvent conditions, corona discharge is commonly observed at emitter tips, r

113 nerates up to +/-5 kV dc voltage to ignite a corona discharge plasma in air for up to 12 h of continu

114 omena linked to negative ionization, such as corona discharge, arcing, and electrospray destabilizati

115 ile nanocarriers with methoxy-terminated PEG coronas do not associate with cells, regardless of size.

116 ptake, a 1.8kgmol(-1) methoxy-terminated PEG corona does not sufficiently protect the nanocarriers fr

117 11 W3 (Lovejoy) passed deep within the solar corona, effectively probing a region that has never been

118 Therein, the C blocks form the stabilizing corona emanating from B compartments, which in turn resi

119 body) so that the composition of the protein corona evolves over time, iii) the physico-chemical char

120 polycyclic granulomas with large lymphocytic coronas, extensive emperipolesis of lymphocytes within m

121 ompared to nanoparticles without a dense PEG corona following local administration by either manual i

122 ld, we introduce the potential impact of the corona for NM-microbiome-(human)host interactions and th

123 main of thrombomodulin (TM) onto the micelle corona for the local generation of activated protein C,

124 lly review and present an updated concept of corona formation and evolution.

125 nce and of the biophysical forces regulating corona formation is mandatory.

126 nsional oligonucleotide structure on protein corona formation, we studied the identity and quantity o

127 gion of the proteins is then surrounded by a corona formed by these molecules, ensuring a hydrophilic

128 lythiophene block copolymer with a different corona-forming block to the resulting nanofibers led to

129 and also the chemistry of the complementary corona-forming block.

130 on of the composition and ratio of core- and corona-forming polymers (indirectly tuning PEGylation de

131 orporated BMA in both the polyplex core- and corona-forming polymers, resulting in robust endosomolys

132 ratios of core-forming polymers to PEGylated corona-forming polymers.

133 oly(ferrocenyldimethylsilane) (PFS) block, a corona-forming segment of poly(2-vinylpyridine) (P2VP),

134 PEGylated, diblock polymers were screened as corona-forming units.

135 ed by use of the Na(+)-sensitive fluorophore CoroNa Green.

136 r sodium-specific fluorescence visualized by CoroNa-Green, a sodium-specific fluorophore, than the wi

137 The structural homology of the daffodil corona has remained a source of debate throughout the hi

138 The presence of this corona has strongly hampered structural studies of solub

139 ntities and amounts of the proteins in this "corona" have been thoroughly examined, the spatial arran

140 nteraction with the NP surface form a "hard" corona (HC), which is believed to mediate NP interaction

141 may influence the composition of the protein corona (i.e. they encounter different proteins on their

142 delivery is the quick formation of a protein corona (i.e., protein adsorbed on the nanoparticle surfa

143 y cannot be used as an adequate indicator of corona ignition.

144 As the corona impacts the in vitro and/or in vivo NM applicatio

145 the exploitation of the nanoparticle-protein corona in analytical chemistry.

146 comet C/2011 N3 (SOHO) within the low solar corona in five wavelength bands in the extreme ultraviol

147 totoxicity, pointing to the role of protein "corona" in conferring the biological impact of amyloidog

148 We demonstrate that the corona initiates as six separate anlagen from hypanthial

149 e early developmental stages and position of corona initiation in Narcissus bulbocodium.

150 images and serial sections demonstrate that corona initiation occurs late in development, after the

151 The protein corona is a dynamic and complex structure whose composit

152 pattern of the C-class gene NbAGAMOUS in the corona is more similar to that of the stamens than that

153 We further describe how the protein corona is related to the synthetic identity of a nanomat

154 The term protein corona is used to describe the coating of the NM surface

155 An important effect of the corona is, however, a reduction in the purely unspecific

156 The Sun's outer atmosphere, or corona, is heated to millions of degrees, considerably h

157 iew, we discuss the formation of the protein corona, its structure and composition, and its influence

158 of apolipoprotein AI (ApoAI) from Si NP hard coronas, leaving unaltered the dispersion physicochemica

159 t target the detection of airborne analytes, Corona/lens-based-collection provides a new path to achi

160 We engineered nanomedicine with the stealth corona made up of densely packed bone seeking ligand, al

161 The presence of a biomolecular corona may confer specific interactions between the nano

162 elective solvent for one of the blocks, core-corona micelle structures are formed.

163 segments provides a promising route to core-corona nanoparticles (micelles) with a wide range of pot

164 The active corona needs additional heating to reach 2,000,000-4,000

165 emically matched MSNP and highlights protein corona neutrality as an important design consideration w

166 timing and magnitude of upward motion to the corona observed 29 s after the event onset in 171 A by t

167 Conjugation to the corona of a single-chain antibody (scFv), which binds to

168 and optionally also bio-conjugates, and the corona of adsorbed biological molecules.

169 ic units" comprising a polyhedral cage and a corona of approximately seven vesicles.

170 lts), which is ascribed to an accretion disk corona of energetic particles akin to those seen in the

171 PT, 1c), are synthesized on the basis of the corona of indeno[1,2-b]fluorene.

172 ng of the behavior of the ubiquitous protein corona of nanomaterials.

173 observed that i) the composition of protein corona of NMs is likely to be dictated by their route of

174 nigma typically invoke the deposition in the corona of nonthermal energy generated by magnetoconvecti

175 ta-amino esters) (PBAEs), possessing a dense corona of polyethylene glycol.

176 and its cognate protein target fused to the corona of protein polymer nanoparticles.

177 ombination, our results demonstrate that the corona of the daffodil N. bulbocodium exhibits stamen-li

178 benign, dome-shaped lesions found around the corona of the penis.

179 Cross-linking of the P2VP corona of the peripheral block in the 2D block co-micell

180 mpetition between the proteins to occupy the corona of the zeolite nanoparticles.

181 o the ROD-Zw10-Zwilch complex in the fibrous corona of unattached kinetochores.

182 The number of proteins present in the corona of zeolite nanoparticles at 100% plasma (in vivo

183 phine ligands immobilized within the soluble coronas of block copolymer micelles is found to induce i

184 low-degree nodes surrounded by hierarchical coronas of hubs, and are uncovered only through the opti

185 , we show that acquisition of a coating, or "corona", of NOM alters the hydrodynamic and electrokinet

186 The protein composition (corona) of zeolite nanoparticles has been shown to be mo

187 To evaluate the effect of a protein corona on stem cell labeling, human mesenchymal stem cel

188 is modulated by the presence or absence of a corona on the nanoparticle surface.

189 al bovine serum (FBS), which forms a protein corona on the surface of the AuNPs.

190 We find that the presence of a serum protein corona on the tip strongly modifies the interaction as i

191 results demonstrate that the effects of NOM coronas on nanoparticle properties and interactions with

192 to other triblock comicelles with different coronas on the central or end segment where "cross" supe

193 cs of AgNWs, due to the formation of a lipid corona or aggregation of the AgNWs.

194 ct of circumcision was stronger at the glans/corona (OR, 0.47; 95% CI, 0.37-0.60) and urethra (OR, 0.

195 a short time scale, described as a "dynamic" corona, others with higher affinity and long-lived inter

196 nteractions lead to the formation of protein coronas, particle wrapping, intracellular uptake and bio

197 In CORONA, patients with heart failure, reduced left ventri

198 modulate the formation of the serum protein corona (PC) and the resultant immune response.

199 l environments, NPs are coated by a 'protein corona' (PC), critically affecting physiological and the

200 Corona phase molecular recognition (CoPhMoRe) uses a het

201 In this work, we applied a new technique, corona phase molecular recognition (CoPhMoRe), to identi

202 tube by chemical adsorption, also form a new corona phase that exhibits highly selective recognition

203 f human blood proteins, revealing a specific corona phase that recognizes fibrinogen with high select

204 e transition also changes the observed SWCNT corona phase, modulating the recognition of riboflavin.

205 We identified several corona phases that enable the selective detection of neu

206 nic HPV, specifically localized to the glans/corona, possibly because of its proximity to the foreski

207 red the responses of coelomocytes to protein coronas preformed of EfCP or FBS.

208 While a 5kgmol(-1) methoxy-terminated PEG corona prevents non-specific uptake, a 1.8kgmol(-1) meth

209 In order to comprehensively analyse corona profiles and to mechanistically understand the co

210 temperature, nanocarrier size, dose, and PEG corona properties.

211 present study, a method to differentiate the corona proteins based on their relative dissociation rat

212 ong enough to penetrate into the Sun's inner corona provide information on the solar atmosphere and m

213 rls showed persistently lower FA in anterior corona radiata (ACR) (group, P = .04; group x age x sex,

214 Greater FA in the anterior corona radiata (ACR) was associated with better inhibiti

215 dal cingulate (M4) motor regions through the corona radiata (CR), internal capsule (IC) and crus cere

216 (CC), superior longitudinal fasciculus (LF), corona radiata (CR), internal capsule (IC) and external

217 The anterior corona radiata (d=0.40) and corpus callosum (d=0.39), sp

218 internal capsule, callosal isthmus, and the corona radiata (p=0.04 for FIQ and p=0.01 for PIQ, corre

219 -0.02 (P = .02); MD, beta = -0.01 (P = .03)] corona radiata and external capsule [right FA, beta = 0.

220 actional anisotropy were evident only in the corona radiata and genu of the corpus callosum.

221 tions of the corpus callosum and beyond (eg, corona radiata and inferior longitudinal fasciculus) acr

222 tropy than control subjects in the posterior corona radiata and the optic radiation (P < 0.002).

223 ant differences also emerged in the anterior corona radiata as well as in white matter underlying the

224 LIC, the cerebral peduncle, and the superior corona radiata than did the HC.

225 tivity to the optic radiations and posterior corona radiata tracts (P < 0.05).

226 Parietal operculum, corona radiata, and internal capsule differences between

227 matter (in corpus callosum, cingulum bundle, corona radiata, and superior fronto-occipital fasciculus

228 ingulum, fornix, stria terminalis, posterior corona radiata, and superior longitudinal fasciculus in

229 lum, fornix, and stria terminalis, posterior corona radiata, and superior longitudinal fasciculus.

230 corpus callosum, the superior and posterior corona radiata, and the cingulum.

231 onal anisotropy (optic radiations, posterior corona radiata, and the splenium region of the corpus ca

232 ferior fronto-occipital fasciculus, superior corona radiata, and uncinate fasciculus.

233 al superior longitudinal fasciculi, superior corona radiata, anterior thalamic radiations, and poster

234 of internal capsule, superior and posterior corona radiata, bilateral external capsule and the right

235 d increases in MD in the bilateral posterior corona radiata, bilateral superior longitudinal fascicul

236 was whole-brain FA in parts of the anterior corona radiata, external capsule, and cerebellum (P<0.05

237 9) evidenced higher FA in the right superior corona radiata, higher FA and AD in bilateral corticospi

238 or G carrier genotypes in the left and right corona radiata, left uncinate fasciculus, left inferior

239 ood ADHD in the right superior and posterior corona radiata, right superior longitudinal fasciculus,

240 tracts, specifically within right posterior corona radiata, right tapetum, and bilateral corpus call

241 um of corpus callosum, anterior and superior corona radiata, superior longitudinal and inferior front

242 in patients with NMO, mainly located in the corona radiata, uncinate fasciculus, corpus callosum, op

243 ddle frontal gyrus white matter and anterior corona radiata.

244 posterior limb of the internal capsule, and corona radiata.

245 al anisotropy in the corpus callosum and the corona radiata.

246 e left thalamic radiation and right anterior corona radiata.

247 within a ROI in the left hemisphere anterior corona radiata.

248 , predominantly in the centrum semiovale and corona radiata.

249 iffusivities in superior (SCR) and posterior corona radiatae (PCR) (group x age x sex, P = .002; grou

250 splenium of corpus callosum, left posterior corona radiate/posterior thalamic radiate, right superio

251 the biological environment, its biomolecular corona, rather than the pristine surface.

252 atmospheric pressure were investigated in a corona reactor energized by +dc, -dc, or +pulsed high vo

253 uced contraction of the poly(ethylene oxide) corona, reducing steric resistance between vesicles and,

254 ave been thought to reside in the peripheral corona region of the kinetochore, distal to microtubule

255 t analysis of the dynamic feature of protein corona related to particle properties.

256 onent of the nanoparticle-associated protein corona renders the associated nanomaterials susceptible

257 m-like CCMs with a homogeneous or patch-like corona, respectively, can be produced.

258 evious observations of Alfvenic waves in the corona revealed amplitudes far too small (0.5 km s(-1))

259 tography from the Cold War-era 'Gambit' and 'Corona' satellite surveillance systems (1965-1969) with

260 le granulomas with subtle/absent lymphocytic coronas, sclerosis of the surrounding tissue, and polymo

261 he SAXS data were well-fitted by a detergent corona shaped in an elliptical toroid around the crystal

262 We comment on how corona signatures may be linked to effects at the nano-b

263 uch breaks also happened before the onset of corona, so they cannot be used as an adequate indicator

264 However, the inhomogeneous turbulent corona strongly affects the propagation of the emitted r

265 LPHN features a core-shell-corona structure that facilitates the transfer and mixin

266 lled Rosuvastatin Multinational Trial in HF (CORONA) study.

267 odel of the n-dodecyl beta-d-maltopyranoside corona surrounding aquaporin-0, the most abundant membra

268 D-Zwilch-ZW10 (RZZ) complex builds a fibrous corona that assembles on mitotic kinetochores before MT

269 is paradigm shifted for the chromosphere and corona that constitute the outer atmosphere, which is no

270 y bind to NMs, forming a protein/biomolecule corona that critically affects the NMs' (patho)biologica

271 The protein corona that forms upon exposure of nanoparticles to bovi

272 interface region between the surface and the corona that is highly sensitive to the coronal heating m

273 tudy, we characterize changes in the protein corona that occur as DOTAP-based lipoplexes are formulat

274 BPN) coated with a dense polyethylene glycol corona that prevents adhesion to ECM components.

275 at possess a dense polyethylene glycol (PEG) corona that prevents them from being trapped by adhesion

276 the chromosphere and the corona) and of the corona that reveal how Alfvenic motions permeate the dyn

277 he acquisition of a surface coating (protein corona) that is determined by the route of entry and phy

278 interface between the Sun's photosphere and corona, the chromosphere and transition region play a ke

279 After cross-linking of the coronas, the branched micelles become resistant to disso

280 m its spectrum), the high temperature of the corona (though the reason for the high temperature remai

281 rianth, stamens, carpel, hypanthial tube and corona tissue.

282 ar periods and may contribute to heating the corona to 1,500,000 K.

283 ained magnetohydrodynamic model of the solar corona to calibrate heliospheric reconstructions based s

284 olyester layer for drug loading, a polar PEO corona to provide biocompatibility, and three different

285 ethod for exploiting the inescapable protein corona to target nanomaterials to specific cells.

286 h the right proportion of the flexible alkyl corona to the rigid core, mesomorphic behavior of one co

287 eric layers, i.e., the transition region and corona, to high temperatures is a long-standing problem

288 in a subset of 1452 patients enrolled in the CORONA trial, which included patients with HF, aged >/=6

289 statin Multinational Trial in Heart Failure (CORONA) trial (n=1329), and at baseline and at 6 months

290 ), and a frame-shifting element from a human corona virus (59 nt).

291 erging zoonotic viruses, including SARS-like corona viruses, henipaviruses, and lyssaviruses, underst

292 Formation of a protein corona was characterized by means of dynamic light scatt

293 h-like polystyrene/poly(methyl methacrylate) corona were prepared.

294 The P2VP coronas were readily removed by photocleavage at the ONB

295 idly coated by proteins, forming a so-called corona which may strongly modify their interaction with

296 A protein corona will be formed on nanoparticles (NPs) entering a

297 riers protected by a hydroxyl-terminated PEG corona with J774 cells is size dependent, while nanocarr

298 s or spicules is accelerated upward into the corona, with much of the plasma heated to temperatures b

299 ed from magnetic reconnection in the tenuous corona, would cause a direct perturbation of the dense p

300 s from worm-like SES CCMs with a homogeneous corona yields triblock co-micelles almost quantitatively