ライフサイエンスコーパス: coronary stenosis

1 major branches in 15 dogs to create chronic coronary stenosis.

2 presence of different degrees of noncritical coronary stenosis.

3 not exacerbate ischemia in canine models of coronary stenosis.

4 with myocardial blood flow and can identify coronary stenosis.

5 failure, or subsequent development of >/=50% coronary stenosis.

6 specially in patients with lesser degrees of coronary stenosis.

7 less significant with increasing degrees of coronary stenosis.

8 l stenosis, and in the larger subset without coronary stenosis.

9 (IBV) mediate autoregulatory adaptations to coronary stenosis.

10 bernating myocardium resulting from a severe coronary stenosis.

11 hysiological significance of an intermediate coronary stenosis.

12 sodilatation in dogs with various degrees of coronary stenosis.

13 sed hibernating myocardium subtending severe coronary stenosis.

14 index to exclude the presence of significant coronary stenosis.

15 est swine (n = 20) were prepared with an 80% coronary stenosis.

16 assessment of the functional significance of coronary stenosis.

17 from age and sex matching and the extent of coronary stenosis.

18 ement can aid in the assessment of left main coronary stenosis.

19 ilitating a cardiac death without verifiable coronary stenosis.

20 ide assessment of functional significance of coronary stenosis.

21 dial infarction patients without significant coronary stenosis.

22 %, respectively, for identifying significant coronary stenosis.

23 plaques, even in the absence of significant coronary stenosis.

24 re independently associated with significant coronary stenosis.

25 n imaging for the detection of flow-limiting coronary stenosis.

26 CA to predict the functional significance of coronary stenosis.

27 th the advantage of providing information on coronary stenosis.

28 er physiologic evaluation of the severity of coronary stenosis.

29 and appears functionally significant during coronary stenosis.

30 iction losses are negligible across a native coronary stenosis.

31 ndromes (ACS) with non-critical angiographic coronary stenosis.

32 dobutamine stimulation before and during the coronary stenosis.

33 This response was blunted during coronary stenosis.

34 by one, three, or six episodes of 90 min of coronary stenosis (30% reduction in baseline coronary fl

35 on) and had greater maximum percent diameter coronary stenosis (59+/-35% versus 38+/-36%; P<0.001).

36 associated with a significant inhibition in coronary stenosis (63+/-3.4% versus 36+/-4.5%; P<0.001),

37 the myocardial segments subtended by severe coronary stenosis (8+/-17% to 40+/-19% and 6.5+/-1.1 to

38 An artificial coronary stenosis (82% diameter reduction) was mounted o

39 resting myocardium subtended to progressive coronary stenosis, a delayed onset of subendocardial thi

40 phy (MCE) can quantify changes in IBV during coronary stenosis and (2) the relation between coronary

41 m/10(4))(-1) in segments without significant coronary stenosis and 0.7+/-0.2 mL . min(-1) . g(-1) . (

42 n opacifying the myocardium and in detecting coronary stenosis and altered transmural distribution of

43 Although the relationship between coronary stenosis and myocardial perfusion is well estab

44 readmill performance, quality of life score, coronary stenosis and myocardial perfusion were compared

45 it could potentially be used to detect both coronary stenosis and myocardial viability after a singl

46 are equivalent in their ability to identify coronary stenosis and quantify altered MBF.

47 were arteriographic evidence of a change in coronary stenosis and the occurrence of a first cardiova

48 high exercise capacity are unlikely to have coronary stenosis and therefore may benefit from initial

49 oncordance of clinical risk with severity of coronary stenosis and to develop and validate a preopera

50 f 83% to predict the presence of significant coronary stenosis and was more accurate than analysis of

51 who underwent combined CMR for suspicion of coronary stenosis and/or ischemia at 2.6 +/- 1.2 years,

52 ary stenosis, subjected to non-flow-limiting coronary stenosis, and after preadministration of caffei

53 s, helps prevent angiographic progression of coronary stenosis, and may prevent cardiovascular events

54 ation class IV, cardiogenic shock, left main coronary stenosis, and valve procedure (c index=0.755).

55 the assumption that friction losses across a coronary stenosis are negligible.

56 with abnormal function for the detection of coronary stenosis as well as the higher sensitivity of d

57 large animal models (eg, swine with chronic coronary stenosis); as well as human subjects.

58 re derived fractional flow reserve (FFR) for coronary stenosis assessment depend on the induction of

59 nostic accuracy for detection of obstructive coronary stenosis at both thresholds of 50% and 70% sten

60 yocardial infarction but without significant coronary stenosis at CA underwent late gadolinium-enhanc

61 in myocardial VI has the potential to detect coronary stenosis at rest without recourse to any form o

62 The ICAs were evaluated for coronary stenosis based on quantitative coronary angiogr

63 reases with increasing levels of noncritical coronary stenosis because of adaptive changes in the mic

64 ) . (mm Hg . bpm/10(4))(-1) in segments with coronary stenosis before PCI (mixed model controlling fo

65 oninvasive imaging modality for detection of coronary stenosis, but it has limited accuracy in demons

66 imaging to opacify the myocardium and detect coronary stenosis by myocardial contrast echocardiograph

67 Angiographically, 549 pt had severe (>60% coronary stenosis) CAD, and 170 had normal coronary arte

68 he aim of the study was to determine whether coronary stenosis can be detected and myocardial viabili

69 nd severity of a physiologically significant coronary stenosis can be detected at rest by measuring t

70 tly, MFR(regional) varied widely within each coronary stenosis category, even in vessels with nonobst

71 perfusion defect (RevPD) from flow-limiting coronary stenosis, CMR late gadolinium enhancement (LGE)

72 nly measure of the hemodynamic severity of a coronary stenosis comparable to fractional flow reserve

73 In patients with intermediate coronary stenosis, coronary pressure and flow velocity w

74 e, coronary thrombosis, myocardial ischemia, coronary stenosis, coronary restenosis, cerebrovascular

75 smatch during hyperemia in the presence of a coronary stenosis correlated closely with the magnitude

76 onally by 6 repetitive episodes of 90-minute coronary stenosis (CS) (30% reduction in baseline corona

77 o represent hibernating myocardium involve a coronary stenosis (CS) to reduce blood flow (BF) and fun

78 The overall sensitivity for the detection of coronary stenosis decreased from 0.76 (95% confidence in

79 ocardial contrast echocardiography, allowing coronary stenosis detection at rest without recourse to

80 Clinical studies have shown a comparable coronary stenosis detection rate between 99mTc-tetrofosm

81 In the absence of coronary stenosis, dobutamine stimulation caused a signi

82 iases due to age and sex matching, extent of coronary stenosis, ethnicity, and study quality.

83 ow reserve (FFR) is a physiologic measure of coronary stenosis expressing the amount of coronary flow

84 During coronary stenosis, flow reserve in the adjacent nonsteno

85 nonischemic (normal) regions after 90-minute coronary stenosis followed by 60-minute reperfusion.

86 69 to 0.94]; P = 0.005) were associated with coronary stenosis greater than 50%.

87 arteries (group I) and 19 with single-vessel coronary stenosis (group II) underwent quantitative coro

88 ars (range 21 to 83 years), and only 18% had coronary stenosis > or =50%.

89 The ability of CMR to detect coronary stenosis >/=70% on X-ray angiography was determ

90 characteristic curve of 0.87 (p < 0.001) for coronary stenosis >/=70%.

91 low-risk patients (score >/=+5), 60% had no coronary stenosis >/=75% and 16% had single-vessel >/=75

92 The entry criteria were > or =1 angiographic coronary stenosis >20% and diastolic BP <100 mm Hg.

93 n <50% (OR 2.49, 95% CI 1.30 to 4.74), final coronary stenosis >30% (OR 2.57, 95% CI 1.28 to 5.15), a

94 ncluded after successful PCI of at least one coronary stenosis (> or =50%).

95 tative angiography (n = 67), 57 patients had coronary stenosis (>50%).

96 alysis, and sensitivity for the detection of coronary stenosis (>or=50% luminal diameter reduction on

97 mibi SPECT imaging for enhanced detection of coronary stenosis has not been established.

98 al stunning was induced in conscious pigs by coronary stenosis, ie, 40% reduction of coronary blood f

99 Coronary stenosis impairs flow reserve in the adjacent n

100 ed normal coronary arteries or insignificant coronary stenosis in 11 patients and significant (> or =

101 ter TAVI changed the indication to treat the coronary stenosis in 8 of 133 (6%) lesions.

102 71%, respectively, for the detection of >75% coronary stenosis in group 1 patients, whereas a ratio o

103 determine: 1) if the presence of significant coronary stenosis in patients presenting with non-ST-seg

104 ood at flow conditions modeling medium-grade coronary stenosis in the Badimon perfusion chamber.

105 By QCA, 25 women (27%) had > or = 50% coronary stenosis, including 10 with single-vessel obstr

106 Focal coronary stenosis increased by 1.4% in the placebo group

107 bility that an angiographically intermediate coronary stenosis is functionally significant.

108 limited accuracy in demonstrating whether a coronary stenosis is hemodynamically significant.

109 Myocardial regions perfused through a coronary stenosis may cease contracting, but remain viab

110 Under left-anterior descending coronary stenosis, MBF increased in response to hypercap

111 inear relation was noted between the percent coronary stenosis measured using quantitative coronary a

112 are indices of functional significance of a coronary stenosis measured without hyperemia.

113 sed a closed-chest pig model of nonocclusive coronary stenosis (n = 14) created by inflating an angio

114 k factors for coronary artery disease, prior coronary stenosis of 50% or more, ST-segment deviation o

115 idetector CT angiography and QCA to detect a coronary stenosis of at least 50%.

116 sitivity and specificity in the detection of coronary stenosis of more than 50% compared with detecti

117 e of coronary calcium could rule out >or=50% coronary stenosis or the need for revascularization.

118 diameter (P = 0.001) and less progression of coronary stenosis (P = 0.002) during follow-up.

119 ounting for 37% of the variance of change in coronary stenosis (P<0.01), followed by reduction in apo

120 l combined with angiographically significant coronary stenosis (P=0.0007), LV ejection fraction (P=0.

121 nts with medically treated angina and severe coronary stenosis, PCI did not increase exercise time by

122 the pathophysiological relationship between coronary stenosis, perfusion, ventricular scar, and myoc

123 ore, CCTA allows comprehensive assessment of coronary stenosis, plaque burden, left ventricular morph

124 ous pigs were subjected to either repetitive coronary stenosis (RCS) or a traditional protocol of sec

125 Coronary stenosis regressed, however, and the primary cl

126 The severity of coronary stenosis related to the double product achieved

127 Coronary stenosis resistance was unchanged.

128 Coronary stenosis resulted in similar reduction in wall

129 n of the occluder to produce a wide range of coronary stenosis severities, we determined the coronary

130 thod may allow the noninvasive assessment of coronary stenosis severity and the detection of microvas

131 equivalent agreement with classification of coronary stenosis severity by HSR.

132 or resting-state physiological assessment of coronary stenosis severity using the instantaneous wave-

133 eversibility at CT perfusion imaging, and (c)coronary stenosis severity was reclassified according to

134 r increase in FFR is associated with greater coronary stenosis severity.

135 FFR is a validated index of coronary stenosis severity.

136 n physicians' angiographic interpretation of coronary stenosis severity.

137 osine-independent, pressure-derived index of coronary stenosis severity.

138 th adenosine in 3 groups of canines: without coronary stenosis, subjected to non-flow-limiting corona

139 a noninvasive anatomic test for diagnosis of coronary stenosis that does not determine whether a sten

140 Long-term benefits of coronary stenosis treatment with an everolimus-eluting b

141 A total of 1058 patients with de novo native coronary stenosis undergoing clinically indicated percut

142 Finally, we estimated the severity of coronary stenosis using the Gensini Scoring system and d

143 Although cardiac CT can identify coronary stenosis, very little data exist on the ability

144 Coronary stenosis was assessed by core laboratory quanti

145 Change in coronary stenosis was assessed by quantitative angiograp

146 Functionally significant coronary stenosis was defined as </=0.8 on FFR.

147 Functionally significant coronary stenosis was defined as FFR </=0.8.

148 ion method was validated in healthy animals, coronary stenosis was induced in seven dogs and contrast

149 eater among patients with more risk factors, coronary stenosis was not present among men <40 years ol

150 was found in 55%, 34%, and 18% and a >/=90% coronary stenosis was present in 25%, 27%, and 19% of pa

151 Significant (>/=50%) coronary stenosis was present in 64 (9.5%) of 674 partic

152 significant coronary artery disease (>/=70% coronary stenosis) was found in 35 (52.2%) patients.

153 , areas under the ROC curve for detection of coronary stenosis were 0.89 and 0.80 (P = .21) for 3.0 a

154 to year and when alternative definitions of coronary stenosis were applied.

155 trumented closed-chest dogs with multivessel coronary stenosis were studied.

156 egative predictive value (>98%) in detecting coronary stenosis when compared with ICA.

157 least 1 significant (> or =70%) angiographic coronary stenosis who were randomly assigned to an initi

158 lymorphism significantly predicts changes in coronary stenosis with lipid-lowering treatment that app

159 st swine the effect of a persistent critical coronary stenosis with moderate flow reduction on ischem