ライフサイエンスコーパス: cortical bone

1 or), and bone type (alveolar bone proper vs. cortical bone).

2 pha(-/-) mice of both genders had unaffected cortical bone.

3 ptosis-focused RT-PCR gene pathways in mouse cortical bone.

4 lar bone network that replaces the amputated cortical bone.

5 reatment may impair toughening mechanisms in cortical bone.

6 lar, they significantly differ from those of cortical bone.

7 d bone mineral density in the trabecular and cortical bone.

8 uctural changes of an intact piece of bovine cortical bone.

9 function RA patients with thinned metacarpal cortical bone.

10 markedly reduced on the endosteal surface of cortical bone.

11 ty, area and strength of both cancellous and cortical bone.

12 scraping device was used to obtain strips of cortical bone.

13 sa, with no allowance for particle escape to cortical bone.

14 th of the HC material to approaching that of cortical bone.

15 ost combinations of source-target regions in cortical bone.

16 hanced bone induction, area of new bone, and cortical bone.

17 d highly in osteocytes within trabecular and cortical bone.

18 carried through the haversian canals within cortical bone.

19 r 6 source-target tissue combinations within cortical bone.

20 ar and palatal tori as sources of autogenous cortical bone.

21 stmenopausal women; the largest effect is on cortical bone.

22 osis in 28% of the osteocytes in metaphyseal cortical bone.

23 oxyapatite-like mineral matrix that makes up cortical bone.

24 r in vivo imaging of bound and pore water in cortical bone.

25 ation artifacts in the lungs, and imaging of cortical bone.

26 in extraction sockets with an intact crestal cortical bone.

27 PET data, because of their ability to image cortical bone.

28 ated in notched and unnotched beams of sheep cortical bone (2x2x20 mm), with monotonic and fatigue lo

29 vented the development of trabecular but not cortical bone abnormalities.

30 s signaling pathway was required for optimal cortical bone accrual at the periosteum in mice.

31 Spaceflight resulted in lower cortical bone accrual in the femur but had no effect on

32 Biopsies of proximal femoral cortical bone adjacent to the fracture site were obtaine

33 CT measurements of area and density of cortical bone aided the differentiation of the various d

34 unknown MR low-intensity class encompassing cortical bones, air cavities, and metal artifacts.

35 veals that the chemical shift frequencies of cortical bone and 10% carbonated apatite are similar but

36 e (UTE) sequences have been used to separate cortical bone and air, and the Dixon technique has enabl

37 g to characterize deficits in trabecular and cortical bone and have evaluated the 'functional muscle-

38 he long bones of mutant mice contain thinner cortical bone and reduced trabecular bone volume.

39 Descriptive bone analysis revealed thin cortical bone and sparse cancellous bone patterns.

40 gher bone area-to-total area ratios, thicker cortical bone and trabecular bone, significantly higher

41 s protection occurred in cancellous, but not cortical, bone and was associated with a failure to incr

42 se was caused by a deficiency of sFRP4, that cortical-bone and trabecular-bone homeostasis were gover

43 Levels of lead in the tibia (representing cortical bone) and the patella (representing trabecular

44 were taken at the 4% (trabecular bone), 20% (cortical bone), and 66% (for measurement of MCSA) sites

45 d polycarbonate to simulate trabecular bone, cortical bone, and cartilage.

46 ed reduced trabecular bone volume, decreased cortical bone, and increased osteoclast number in bone e

47 s, the rate of bone formation was reduced in cortical bone, and the parietal bones were 45% thinner t

48 gulator of bone mass with high expression in cortical bone, and Wnt16(-/-) mice have reduced cortical

49 Trabecular bone, as compared with cortical bone, appeared highly heterogeneous on the scat

50 used this technique to study trabecular and cortical bone architecture.

51 (43)Ca NMR spectra of bovine cortical bone are analyzed by comparing to the natural-a

52 on (ICRP)-recommended absorbed fractions for cortical bone are given only for the CBE as target regio

53 cts of parathyroid hormone on trabecular and cortical bone are primarily mediated via G(s)alpha in os

54 oup had lower bone measures at the 20% site (cortical bone area and cortical BMC at the tibia, total

55 moral bone volume, trabecular thickness, and cortical bone area and thickness were significantly incr

56 ercentage BF was inversely related to radial cortical bone area, total bone cross-sectional area (CSA

57 varying thicknesses (0.5 to 4 mm) of buccal cortical bone around the implants.

58 mounts of trabecular bone and unusually thin cortical bone, as a result of differential regulation of

59 Folfiri nor ACVR2B/Fc had effects on femoral cortical bone, as shown by unchanged cortical bone volum

60 leads to geometric and structural changes in cortical bone, as well as asymmetry in fracture healing.

61 situ beneath the periosteal surface of mouse cortical bone at depths up to 50 microm with laser scann

62 ted mice) and in the width and volume of the cortical bone at the femoral diaphysis (+24% and +20%, r

63 ted bone was equivalent to that of untreated cortical bone at week 4, while the bone hardness around

64 ree-dimensional electron transport model for cortical bone based on Monte Carlo transport and on bone

65 Porcine cortical bone blocks were subjected to defatting, differ

66 histomorphometrically for area of new bone, cortical bone, bone marrow, and residual DFDBA.

67 osteocytes is critical for full anabolism in cortical bone, but tempers bone gain in cancellous bone.

68 PTH increased the HyA content of cortical bone by 2-fold while not affecting the HyA cont

69 t 3.0 T and was validated in sheep and human cortical bone by using exchange of native water with deu

70 While canals in cortical bone can readily be identified and characterise

71 ated Wnt16 expression in both trabecular and cortical bone compared with wild type (WT) mice.

72 of estrogens on the cancellous, but not the cortical, bone compartment that represents 80% of the en

73 ity was increased in both the trabecular and cortical bone compartments in nestin-ERalpha(-/-) mice c

74 reover, the buccal and mesial regions of the cortical bone concentrated significantly higher stress (

75 btraction mask to eliminate high-attenuation cortical bone contours.

76 with antibodies to sclerostin corrected the cortical-bone defect.

77 been confirmed as representing osteitis and cortical bone defects, respectively, adding to what was

78 Muscle attenuation as well as trabecular and cortical bone densities revealed negative correlations w

79 We measured trabecular bone densities, cortical bone densities, VAT areas, and subcutaneous adi

80 implicate Aldh1a1 as a novel determinant of cortical bone density and marrow adiposity in the skelet

81 (HR-pQCT), we demonstrate low trabecular and cortical bone density contributing to lower volumetric b

82 y with estrogen has been reported to improve cortical bone density in postmenopausal women with asymp

83 the cross-sectional area, cortical area, and cortical bone density of the femoral shaft and the cross

84 r number and increased separation; the lower cortical bone density results from thinner cortices, whe

85 x, age, height, and weight did not influence cortical bone density; values were similar for the 17 co

86 Cyclical growth marks in cortical bone, deposited before attainment of adult body

87 Cortical bone-derived stem cells (CBSCs) and cardiac-der

88 tly reduced both reactive bone formation and cortical bone destruction by CM from LAC cultures.

89 was conducted to identify the role of Scx in cortical bone development and fracture healing.

90 decreased bone resorption and an increase in cortical bone due to increased bone formation.

91 atient--eg, the knee), beam hardening (about cortical bone--eg, the femoral shaft), and cone-beam art

92 t regions: the cortical haversian space, the cortical bone endosteum (CBE) and the cortical bone volu

93 metric placement of trabecular bone within a cortical bone envelope represents yet another mechanism

94 d contrast enhancement decrease, but fat and cortical bone-equivalent signal intensity increases.

95 F-alpha-dependent systemic inflammation, and cortical bone erosion.

96 The structure of human cortical bone evolves over multiple length scales from i

97 he radius, a skeletal site that is primarily cortical bone, exist and also differ by sex.

98 econd, to evaluate the histologic effects on cortical bone following irradiation with increasing ener

99 ls showed positive outcome on trabecular and cortical bone formation in extraction sockets with an in

100 th either maintained (trabecular) or higher (cortical) bone formation as compared to vehicle-treated

101 Cortical-bone fragility is a common feature in osteoporo

102 ortical bone free water T1 (R(2) = 0.72) and cortical bone free water concentration (R(2) = 0.62) sho

103 Conclusion The cortical bone free water concentration and free water T1

104 Cortical bone free water T1 (R(2) = 0.72) and cortical b

105 ficiency promoted progressive cancellous and cortical bone gain in both mutants, although more pronou

106 lone had greatly reduced trabecular density, cortical bone geometry properties, and bone mineral cont

107 Substantial deficits in trabecular vBMD, cortical bone geometry, and muscle were observed at CD d

108 size, muscle mass, trabecular bone density, cortical bone geometry, and strength.

109 with hyaluronic acid (HY) and cancellous and cortical bone granules from the same donor: DBM alone (1

110 oss on the material properties of mandibular cortical bone have received little study.

111 and differentially regulates trabecular and cortical bone homeostasis.

112 Regulation of cortical-bone homeostasis has proved elusive.

113 terized by radiolucent lesions affecting the cortical bone immediately under the periosteum of the ti

114 r the trabecular bone in female mice and the cortical bone in both genders.

115 ble for trabecular bone in male mice and for cortical bone in both genders.

116 ant for trabecular bone in male mice and for cortical bone in both males and females.

117 s, and there was complete destruction of the cortical bone in much of the proximal tibias by 4 weeks.

118 d (ii) an osteoporosis mouse model comparing cortical bone in sham-treated and ovariectomized mice.

119 e PET/CT, PET/MR ignores the contribution of cortical bone in the attenuation map.

120 in the cortical vertebrae in one strain) and cortical bone in the calvariae (bone mineral density was

121 Trabecular and cortical bone in the distal metaphysis was made osteopor

122 Mandibular cortical bone in the edentulous mandibles differed from

123 ne accrual in the femur but had no effect on cortical bone in the humerus or calvarium.

124 The area and density of cortical bone in the midshaft of the femur were measured

125 longitudinal relaxation time [T1]) of human cortical bone in vivo.

126 ion in osteoblasts and osteocytes lining the cortical bone, in chondrocytes and in the sinus lining c

127 Implants placed in sites with thin cortical bone increased the chance for a patient to lose

128 ory cytokines, through small perforations of cortical bone, increases the rate of bone remodeling and

129 It was found that fracture in human cortical bone is consistent with strain-controlled failu

130 s show that the true transverse toughness of cortical bone is far higher than previously reported.

131 ilar but the quadrupole coupling constant of cortical bone is larger than that measured for model com

132 rom the phase information of the first echo; cortical bone is segmented using a dual-echo technique.

133 n in periosteal bone callus formation at the cortical bone junction as determined by MicroCT and hist

134 homozygous for the ALAD-1 allele have higher cortical bone lead levels; this implies that they may ha

135 esembles characteristics of younger, healthy cortical bone, leads to improved bone quality.

136 Occasionally, unusual apposition of cortical-bone-like layers in bone marrow space was obser

137 age analysis algorithm were used to quantify cortical bone loss and periosteal new bone formation for

138 This suggests a slight reversal of cortical bone loss that may be partially due to higher f

139 of endogenous WNT16 results specifically in cortical bone loss, whereas overexpression of WNT16 surp

140 ets, while CD4+ T cells additionally induced cortical bone loss.

141 eak bone mass and age-related trabecular and cortical bone loss.

142 rs who continued throwing during aging, some cortical bone mass and more strength benefits of the phy

143 We observed significant increases in cortical bone mass and strength, notably in cortical tis

144 Estradiol increased the trabecular and cortical bone mass as well as the uterine weight, wherea

145 -/-) ) female mice had higher trabecular and cortical bone mass compared to age and sex-matched contr

146 reases at the time of a transient deficit in cortical bone mass due to the increased calcium demand d

147 a dramatic reduction of both trabecular and cortical bone mass in homozygous mutants.

148 eased bone formation and thus cancellous and cortical bone mass in skeletally mature rodents.

149 with estradiol increased the trabecular and cortical bone mass to a similar extent in both Wnt16(-/-

150 Once throwing activities ceased, the cortical bone mass, area, and thickness benefits of phys

151 terine weight, whereas no effect was seen on cortical bone mass, fat mass, or thymus weight.

152 etons as evidenced by reduced trabecular and cortical bone mass, lower bone mineral density, and a sl

153 eage show significantly lower trabecular and cortical bone mass, serum and bone marrow PDGF-BB concen

154 ice) yielded markedly reduced trabecular and cortical bone mass.

155 tical bone, and Wnt16(-/-) mice have reduced cortical bone mass.

156 ontributes to bone repair and maintenance of cortical bone mass.

157 r osteocytes did not influence cancellous or cortical bone mass.

158 Both trabecular and cortical bone measurements by micro-CT did not reveal an

159 he first study to explore the role of Scx in cortical bone mechanics and fracture healing.

160 for bone mineral density and trabecular and cortical bone microarchitecture.

161 area, total bone cross-sectional area (CSA), cortical bone mineral content (BMC), periosteal circumfe

162 structure and increased both trabecular and cortical bone mineral densities in a dose-related fashio

163 t of renal transplantation on trabecular and cortical bone mineral density (BMD) and cortical structu

164 hin close proximity of the joints as well as cortical bone mineral density and periosteal new bone fo

165 al density, whereas ST-SPI diet only reduced cortical bone mineral density loss 3 wk post-OVX.

166 Cortical bone mineral density was significantly higher i

167 tions in cortical porosity and increments in cortical bone mineral density with OPG in PPR*Tg mice we

168 iminished the loss of total, trabecular, and cortical bone mineral density, whereas ST-SPI diet only

169 were internally coated with pulverized human cortical bone mixed with epoxy glue to simulate minimal

170 ough estimate yields an OH- content of human cortical bone of about 20% of the amount expected in sto

171 ulated in osteoblast-like cells derived from cortical bone of female Prkca(-/-) mice compared with WT

172 Cortical bone of Gnas(+/p-) mice showed elevated express

173 icient women, particularly on the hip and on cortical bone of the total body, are unknown.

174 , Notch2(Q2319X) mice exhibit cancellous and cortical bone osteopenia, enhanced osteoclastogenesis, a

175 1 month of age they exhibited cancellous and cortical bone osteopenia.

176 gnificantly lower yttrium uptake in bone and cortical bone over a 10-d period when DOTA was used as t

177 e in bone mineral density and trabecular and cortical bone parameters.

178 trabecular micro-architecture and preserved cortical bone parameters.

179 , MGUS patients have significantly increased cortical bone porosity and reduced bone strength relativ

180 etermined significance (MGUS) have increased cortical bone porosity and reduced bone strength,1 condi

181 A marker of cortical bone porosity called porosity index was defined

182 A two-point MR imaging method to assess cortical bone porosity in humans was conceived and valid

183 ging-derived SR may serve as a biomarker for cortical bone porosity that is potentially superior to B

184 ential for clinical use to assess changes in cortical bone porosity that result from disease or in re

185 nsity characterized by severe trabecular and cortical bone porosity, marked thinning of the parietal

186 given the plasticity of mammalian diaphyseal cortical bone, provides insights into the habitual level

187 eletion of Gnas (Gnas(+/p-)) have defects in cortical bone quality and strength during early developm

188 eatures include osteomalacia, thinned/porous cortical bone, reduced processing of procollagen and den

189 reased approximately 50% at the distal femur cortical bone region but not at trabecular bone region a

190 of apoptotic osteocytes was increased at the cortical bone region by approximately 40% initially obse

191 bone microstructural information for several cortical bone regions.

192 While the essential role of periosteum in cortical bone repair and regeneration is well establishe

193 This was probably due to decreased cortical bone resorption, because osteoclasts were marke

194 both marrow and endosteum in trabecular and cortical bone, respectively.

195 Porosity index of midtibia cortical bone samples obtained from 16 donors was compar

196 R experiments on bone, using powdered bovine cortical bone samples.

197 ressures between occluding teeth that exceed cortical bone shear strength, thereby permitting access

198 e sites when maintaining excess body weight, cortical bone showed a trend in the opposite direction.

199 crocomputed tomography (microCT) analysis of cortical bone showed that hPTH-infusion induced signific

200 3, 44%; grade 4, 4%), (b) increasing fat and cortical bone signal intensity at T1-weighted imaging (g

201 ght, weight, and bone area, was decreased at cortical bone sites (1/3 radius, upper and lower extremi

202 ons of energy were tabulated for three adult cortical bone sites considering three source and target

203 had decreased tibia trabecular bone density, cortical bone size and strength, and muscle mass.

204 Cortical bone size, trabecular bone volume, bone mineral

205 ring the diffusion fluxes of tissue water in cortical bone specimens from the midshaft of rabbit tibi

206 micro-CT-derived porosity in 13 donor human cortical bone specimens.

207 RATIONALE: Cortical bone stem cells (CBSCs) have been shown to redu

208 We showed that mesenchymal stromal cells, cortical bone stem cells, and tail-tip fibroblasts fuse

209 d predictors of age-related deterioration of cortical bone structure and are potentially superior to

210 w predictor for age-related deterioration of cortical bone structure.

211 ensitometry, preferably at a site containing cortical bone, such as the hip or forearm.

212 t crack-growth resistance behaviour of human cortical bone that accurately assesses its toughness at

213 In cortical bone, the scattering signal was significantly h

214 In the rat tibia cortical bone, the scattering signals from two orthogona

215 bone crest; 2) tooth torque (TT); 3) labial cortical bone thickness (BT) for alveolar and basal bone

216 analyses revealed a significant reduction in cortical bone thickness and an increase in trabecular th

217 Histomorphometry confirmed increased cortical bone thickness and demonstrated significantly h

218 The WNT16 locus is a major determinant of cortical bone thickness and nonvertebral fracture risk i

219 Finally, cortical bone thickness and trabecular volume, as well a

220 mineral density, trabecular bone volume, and cortical bone thickness compared with control littermate

221 f this cadaver study to determine an average cortical bone thickness in different tooth locations.

222 However, information about cortical bone thickness in various regions of the maxill

223 rtilage thickness decreased, and subchondral cortical bone thickness increased in the posterior tibia

224 Measurements were made of the cortical bone thickness of the harvested ramus graft and

225 in trabecular bone volume and a decrease in cortical bone thickness of the long bones.

226 ient mice expressed increased trabecular and cortical bone thickness producing mechanically stronger

227 A significant reduction in cortical bone thickness was also found in the sham/HP gr

228 ificantly reduced trabecular bone volume and cortical bone thickness, associated with increased osteo

229 ad increased bone mineral density, increased cortical bone thickness, higher rate of bone formation,

230 signaling was critical for achieving proper cortical-bone thickness and stability.

231 There is an association between metacarpal cortical bone thinning and obstruction or incompressibil

232 a genetic disorder that is characterized by cortical-bone thinning, limb deformity, and fractures; t

233 the majority of BW is in the pore system of cortical bone, this parameter provides a surrogate measu

234 t enhanced the HyA staining of osteocytes in cortical bone tissue sections to the extent that the lac

235 Decreases in cortical bone, trabecular bone, and whole-bone failure s

236 Micro-finite-element models for cortical bone, trabecular bone, and whole-bone section w

237 Decreases in cortical bone, trabecular bone, and whole-bone stiffness

238 becular bone volume and greater increases in cortical bone turnover, than did PTH(1-34).

239 transverse and longitudinal orientations in cortical bone, using both crack-deflection/twist mechani

240 The material behavior of cortical bone varied in three ways: isotropic homogeneou

241 e, the cortical bone endosteum (CBE) and the cortical bone volume (CBV).

242 images of mouse paws for evaluation of joint cortical bone volume (JCBV) within close proximity of th

243 femoral cortical bone, as shown by unchanged cortical bone volume fraction (Ct.BV/TV), thickness (Ct.

244 metry (DXA) scanning, and the trabecular and cortical bone volume was determined by microfocal comput

245 +/+), Postn(-/-) mice had a lower bone mass, cortical bone volume, and strength response to PTH.

246 n was -0.321, between BMI and the density of cortical bone was -0.250, and between BMI and trabecular

247 second group of specimens consisting only of cortical bone was irradiated by a single pass of the las

248 In contrast, cortical bone was thickened with narrowing of the bone m

249 he medullary cavity and/or thickening of the cortical bone-was assessed.

250 The dimension and volume of the neighboring cortical bone were adequate, and the augmented edentulou

251 veolar bone proper and more distant osteonal cortical bone were estimated.

252 l sites, regions of trabecular spongiosa and cortical bone were identified and segmented.

253 The maximum principal stress values for cortical bone were measured at the mesial, distal, bucca

254 d bone matrix chord length distributions for cortical bone were randomly sampled to create alternatin

255 us the anterior pillar is a hollow column of cortical bone, whereas in A. robustus it is a column of

256 e strength is determined by its outer shell (cortical bone), which forms by coalescence of thin trabe

257 there are no data on whether the porosity of cortical bone, which may play a greater role in bone str

258 Cortical bone width and trabecular thickness in Dicer(De

259 Severely affected lines also showed reduced cortical bone width.

260 ly, this new transport model of electrons in cortical bone will improve the relatively energy-indepen

261 quantify free and bound water components of cortical bone with a model-based numeric approach with u

262 apping bound and pore water in vivo in human cortical bone with practical human MR imaging constraint

263 r skeleton is compromised because of thinner cortical bone, with a low periosteal circumference and a

264 ases in BMD over 24 months at trabecular and cortical bone, with overall AE rates similar to those of