ライフサイエンスコーパス: cortical cataract

1 ependently associated with increased risk of cortical cataract.

2 HFR polymorphisms via homocysteine levels to cortical cataract.

3 separately and jointly to increased risk of cortical cataract.

4 and metabolic syndrome were associated with cortical cataract.

5 and inappropriate activity may contribute to cortical cataract.

6 that Ofl may be a model of human pulverulent cortical cataract.

7 ative importance of genes and environment in cortical cataract.

8 sed to determine the underlying liability to cortical cataract.

9 ay be related weakly to incident nuclear and cortical cataract.

10 s cell calcium has long been associated with cortical cataract.

11 size is a major risk factor for nuclear and cortical cataracts.

12 al volunteers and volunteers with nuclear or cortical cataracts.

13 lear cataract, 1.62 (95% CI: 0.92, 2.85) for cortical cataract, 1.95 (95% CI: 0.48, 7.95) for posteri

14 Multivariate adjustment showed that pure cortical cataract (197 eyes) was significantly associate

15 In studies of cortical cataract, a severity score representing the are

16 s) and 95% confidence intervals for incident cortical cataract, after adjusting for age, sex, smoking

17 effects are important in the development of cortical cataract and involve the action of dominant gen

18 due to two novel PAX6 mutations; progressive cortical cataract and lamellar cataract with lens sublux

19 aA-crystallin subunits resulted in posterior cortical cataracts and abnormalities associated with the

20 the PP1-treated lenses showed development of cortical cataract, and the average area of opacity was j

21 will be 167,000-830,000 additional cases of cortical cataract by 2050.

22 Risk of cortical cataract by contrast fell with increasing birth

23 lear (NSC), posterior subcapsular (PSC), and cortical cataract (CC), using the new WHO Simplified Cat

24 In aged mice, most subcapsular and cortical cataracts colocalize with accumulations of nucl

25 Cortical cataracts develop in FE65L1 knockout (KO) mice

26 In multivariate analysis, age, sex (male), cortical cataract, diabetes, nuclear cataract, and forme

27 t that repression of estrogen action induces cortical cataract formation because estrogen is required

28 felodipine or nifedipine induces progressive cortical cataract formation with time, in association wi

29 he Salisbury Eye Evaluation Study, a digital cortical cataract grading algorithm was used to capture

30 Prevalence of significant cortical cataract (>/=5% of lens area) was similar in mo

31 The association between PXS and cortical cataract, however, did not persist after furthe

32 and serum homocysteine levels with incident cortical cataract in an older population.

33 Cortical cataract in humans is associated with Ca2+ over

34 ay be a therapeutic target to reduce risk of cortical cataract in persons carrying genetic risk.

35 risk of development of mild nuclear or mild cortical cataracts in participants not taking Centrum (P

36 ole for vitamin C in diminishing the risk of cortical cataracts in women aged <60 y and for carotenoi

37 idence interval [CI], 2.07-3.70; P < 0.001); cortical cataract increase of 5% or more in lens opacity

38 Modeling suggested liability to cortical cataract is explained by additive and dominant

39 ilure and the development of subcapsular and cortical cataracts is observed in Mbnl3(DeltaE2) mice.

40 The current genome scan for age-related cortical cataracts may lead to identification of novel g

41 ll of which exhibit posterior nuclear and/or cortical cataracts of variable severity.

42 taract status graded by the Wilmer protocol (cortical cataract: opacity >or=4/16; nuclear cataract gr

43 no follow-up data or DNA or who had previous cortical cataract or cataract surgery, 757 participants

44 levels were associated with a 3-fold risk of cortical cataract (OR = 3.74; 95% CI = 1.79-7.80).

45 aract: OR, 0.62; 95% CI, 0.43-0.88; and mild cortical cataract: OR, 0.77; 95% CI, 0.63-0.95.

46 aract: OR, 0.62; 95% CI, 0.43-0.90; and mild cortical cataract: OR, 0.80; 95% CI, 0.65-0.99.

47 phaB and betaB1 was significantly related to cortical cataract (P <or= 0.05).

48 , 1.73; 95% CI, 1.10-2.72) cataract, but not cortical cataract (P = 0.64); each millimeter increase i

49 XS had a significantly greater prevalence of cortical cataract (P=.02) and nuclear cataract (P < .000

50 oled OR 1.93, 95% CI 1.49-2.49) but not with cortical cataract (pooled OR 1.08, 95% CI 0.90-1.30).

51 me ocular exposure to ultraviolet B light on cortical cataract risk for each lens region was examined

52 haplotypes show a stronger association with cortical cataract (rs3761382, P = 0.002, OR = 2.1; rs130

53 t may not entirely explain the variations in cortical cataract severity across the lens.

54 The lower nasal regions had the highest cortical cataract severity in both the right and left ey

55 In the ER Delta 3 transgenic mice, cortical cataracts spontaneously form in ER Delta 3 fema

56 io (0.43; 95% CI: 0.2, 0.93) of developing a cortical cataract than was an intake <140 mg/d, and use

57 explained 26% and 37% and age 16% and 11% of cortical cataract variance in clinical and digital gradi

58 Five-year incidence of cortical cataract was 9.9% in statin users and 7.5% in n

59 Cortical cataract was assessed using the slit-lamp-based

60 h analysis showed that the genetic effect on cortical cataract was partially mediated via homocystein

61 To identify susceptibility loci for cortical cataracts, we genotyped a subset of families (1

62 Estimates of the broad sense heritability of cortical cataract were 58% (95% confidence interval [CI]

63 ular exposure to ultraviolet B radiation and cortical cataract were derived from a population-based s

64 studies, posterior subcapsular, nuclear, and cortical cataracts were associated with visual impairmen

65 etermine whether age-related subcapsular and cortical cataracts were linked to the failure of lens fi

66 In one phakic member, the cortical cataracts were punctate and vacuolated.

67 s between hyperopia and incident nuclear and cortical cataracts were unchanged.

68 is indicated that by 2050, the prevalence of cortical cataract will increase above expected levels by