ライフサイエンスコーパス: cortical dysplasia

1 ological evidence of developmental tumors or cortical dysplasia.

2 arachnoid space results in the formation of cortical dysplasia.

3 y, centrally predominant polymicrogyria-like cortical dysplasia.

4 l organization consistent with type Ia focal cortical dysplasia.

5 terotopia and diffuse megalencephaly without cortical dysplasia.

6 to differentiate between type I and type II cortical dysplasia.

7 factors are involved in the pathogenesis of cortical dysplasia.

8 ly had schizencephaly, heterotopia, or focal cortical dysplasia.

9 athological aging, and the presence of focal cortical dysplasia.

10 meningeal differentiation can lead to severe cortical dysplasia.

11 aches for childhood epilepsy associated with cortical dysplasia.

12 daptor proteins, FE65 and FE65L1, results in cortical dysplasia.

13 t in epilepsy and mental retardation without cortical dysplasia.

14 bitory synaptic transmission in experimental cortical dysplasia.

15 y a causal role in the pathogenesis of focal cortical dysplasias.

16 well as in the pathogenesis of certain human cortical dysplasias.

17 g patients with tumor (36 of 44, 82%) versus cortical dysplasia (16 of 31, 52%).

18 velopmental abnormalities consisted of focal cortical dysplasia (5), heterotopia (2), hamartoma (3),

19 aly and intractable epilepsy, one with focal cortical dysplasia and intractable epilepsy, and one dys

20 is linked to the first description of focal cortical dysplasia and limbic encephalitis, the patholog

21 Cortical dysplasia and low-grade tumor were the most com

22 n utero irradiation of rats produces diffuse cortical dysplasia and neuronal heterotopia in the neoco

23 a, two focal cortical dysplasia, one diffuse cortical dysplasia and one microdysgenesis), acquired in

24 dysplasia (such as hemimegalencephaly, focal cortical dysplasia and polymicrogyria).

25 f central pachygyria and polymicrogyria-like cortical dysplasia and simplified gyral malformation syn

26 cytomegalic neurons in focal or hemispheric cortical dysplasia and to determine whether the activity

27 ficial, particularly for patients with focal cortical dysplasia and unilateral hemispheric malformati

28 out the prevalence of HPV infection in focal cortical dysplasias and about its potential importance a

29 In general, three types of cortical dysplasia are recognized.Type I focal cortical

30 ents, including hemimegalencephaly and focal cortical dysplasia, are common causes of intractable pae

31 egalencephaly, hemimegalencephaly, and focal cortical dysplasia as part of a single pathogenic spectr

32 Long-term overexpression of Wnt3a led to cortical dysplasia associated with the formation of larg

33 iation that is transient and localized, with cortical dysplasia at later stages.

34 Binding was reduced within focal cortical dysplasia but increased in adjacent cortex.

35 The remainder had a polymicrogyria-like cortical dysplasia, but the grey matter malformation was

36 Cortical dysplasia can be caused by cellular defects in

37 two groups: patients with highly asymmetric cortical dysplasia caused by the common p.E17K mutation,

38 Cortical dysplasia (CD) is often associated with pharmac

39 in brain samples resected from patients with cortical dysplasia (CD), which was correlated with durat

40 The cortex of patients with cortical dysplasia contains several abnormal cell types.

41 Balloon cells (BCs) in focal cortical dysplasia (FCD) and giant cells (GCs) in tubers

42 ons of cortical development, including focal cortical dysplasia (FCD) and hemimegalencephaly (HME), a

43 Focal cortical dysplasia (FCD) are associated with neurologica

44 nd ultrastructural patterns in type II focal cortical dysplasia (FCD) have been studied to explain th

45 ocal epilepsy, one of each pair having focal cortical dysplasia (FCD) IIa.

46 ming to facilitate detection of subtle focal cortical dysplasia (FCD) in MRI- patients.

47 Focal cortical dysplasia (FCD) is a common and important cause

48 f tuberous sclerosis complex (TSC) and focal cortical dysplasia (FCD) is early life refractory epilep

49 Focal cortical dysplasia (FCD) type II is an important cause o

50 Focal cortical dysplasia (FCD), a local malformation of cortic

51 This figure is the same for focal cortical dysplasia (FCD), the most common variety of MCD

52 x (TSC)-associated cortical tubers and focal cortical dysplasia (FCD), we performed qualitative and s

53 e epilepsy (FLE) that is distinct from focal cortical dysplasia (FCD).

54 reas contained mainly non-balloon-cell focal cortical dysplasia (FCD).

55 detecting and delineating microscopic focal cortical dysplasia (FCD).

56 pithelial tumours (DNTs; eight cases), focal cortical dysplasia (FCD; 14 cases) and hippocampal scler

57 ohistochemistry in the core of type II focal cortical dysplasias (FCD-II), at the FCD boundary (peril

58 Focal cortical dysplasias (FCDs) are malformations of cortical

59 o further extend the role of DEPDC5 to focal cortical dysplasias (FCDs).

60 of CNTNAP2 in Old Order Amish children with cortical dysplasia, focal epilepsy, relative macrocephal

61 In the developmental group, low-grade focal cortical dysplasias had better outcome than heterotopia

62 Cortical dysplasia has a strong association with epileps

63 he complex structural abnormalities of focal cortical dysplasia have been proposed - from Taylor et a

64 splay type I lissencephaly, a severe form of cortical dysplasia hypothesized to result from abnormal

65 edge, this is the first report of cerebellar cortical dysplasia in a family with AOS.

66 ssibility that primary meningeal defects may cortical dysplasia in some cases.

67 lioneuronal heterotopias are a focal type of cortical dysplasia in which neural cells migrate aberran

68 Cortical dysplasia is a major cause of intractable epile

69 Focal cortical dysplasia is a malformation of cortical develop

70 h drug-resistant epilepsy.However, in type I cortical dysplasia, MR imaging is often normal, and also

71 ) central pachygyria and polymicrogyria-like cortical dysplasia (n = 24); (iv) generalized polymicrog

72 = 24); (iv) generalized polymicrogyria-like cortical dysplasia (n = 6); and (v) a 'simplified' gyral

73 eveal the presence and the border of type II cortical dysplasia on MRI, a quantitative ROI-based anal

74 egalencephaly, two polymicrogyria, two focal cortical dysplasia, one diffuse cortical dysplasia and o

75 diagnosed with multiple sclerosis, one with cortical dysplasia, one with pineal hemorrhage and one w

76 suggests that new cells may arrive in focal cortical dysplasia, perhaps deriving in part from the su

77 f the most common or enlightening MCD: focal cortical dysplasia, periventricular heterotopia, polymic

78 Cortical dysplasia resembling cobblestone cortex, with b

79 tardation and seizures associated with focal cortical dysplasias, subependymal nodules, and subependy

80 growth (megalencephaly) as well as segmental cortical dysplasia (such as hemimegalencephaly, focal co

81 ranges from lissencephalic to polymicrogyric cortical dysplasias, suggesting shared pathogenic mechan

82 n large dysplastic cells microdissected from cortical dysplasia surgical specimens was used to identi

83 for surgical outcome in patients with focal cortical dysplasia than the presence of a lesion on magn

84 megalencephaly, hemimegalencephaly and focal cortical dysplasia, the most common cause of intractable

85 ype II dysplasias and in only some of type I cortical dysplasias.THE MOST COMMON FINDINGS ON MRI IMAG

86 trocytes of all hemimegalencephaly and focal cortical dysplasia type II specimens, regardless of the

87 egalencephaly, hemimegalencephaly, and focal cortical dysplasia type IIa.

88 Focal cortical dysplasia type IIB (FCDIIB) is a sporadic devel

89 The etiology of focal cortical dysplasia type IIb (FCDIIb) remains enigmatic i

90 We identified 14 specimens of focal cortical dysplasia type IIb from a single surgical cente

91 Focal cortical dysplasia type IIB with Ballon cells is a devel

92 association between HPV infection and focal cortical dysplasia type IIb, and its reproducibility acr

93 roportion of pathological specimens of focal cortical dysplasia type IIb, but not in control specimen

94 nical symptoms are more severe in type II of cortical dysplasia usually seen in children.

95 thological diagnosis among adults, and focal cortical dysplasia was the most common diagnosis among c

96 ions of cortical development in 19.8% (focal cortical dysplasia was the most common type, 52.7% of ca

97 or the cognitive impairment in the rats with cortical dysplasia was the underlying brain substrate, n

98 with focal or multifocal polymicrogyria-like cortical dysplasia with abnormal and simplified gyral pa

99 rtical dysplasia are recognized.Type I focal cortical dysplasia with mild symptomatic expression and

100 Patients with focal cortical dysplasia, with and without a detectable lesion

101 esected TSC tubers, FCDs with balloon cells, cortical dysplasia without balloon cells, and histologic