ライフサイエンスコーパス: cortical hem

1 hh develop a dorsal telencephalic midline, a cortical hem, and two cortical hemispheres.

2 ssed in the cortical hem, and in its absence cortical hem progenitors contribute excessively to the a

3 xpression of transthyretin mRNA, the CPe and cortical hem are linked by shared expression of members

4 phalic structures, including hippocampus and cortical hem, while the ventral telencephalon appears to

5 functions to repress the generation of both cortical hem- and PSB-derived CR cells.

6 fate mapping studies, as a novel marker for cortical hem- and septum-derived CR cells.

7 lation of TGFbeta signaling in explants from cortical hems of wild-type mice altered p21 expression a

8 ephalic dorsal midline structures, including cortical hem, hippocampus and choroid plexus, either fai

9 orsal midline signaling in the production of cortical hem- and PSB-derived CR cells.

10 onstrate that, although the specification of cortical hem-derived CR cells is dependent on signaling

11 The Wnt-rich cortical hem is a transient, neuron-containing, neuroepi

12 in forebrain signalling centres-the septum, cortical hem and the pallial-subpallial boundary-known t

13 The cerebellar rhombic lip and telencephalic cortical hem are dorsally located germinal zones which c

14 cerebellar rhombic lip and the telencephalic cortical hem.

15 The cortical hem is an embryonic signaling center that gener

16 The cortical hem, a source of Wingless-related (WNT) and bon

17 In addition, although the cortical hem does not show features of differentiated CP

18 source of fibroblast growth factors and the cortical hem, a medial structure expressing winglessint

19 ate, which expresses Fgf8 and Fgf17, and the cortical hem, which expresses Bmps and Wnts.

20 expresses fibroblast growth factors, and the cortical hem, which expresses bone morphogenetic protein

21 that Wnt gene expression is deficient at the cortical hem in XtJ/XtJ mice, but that the expression of

22 close developmental relationship between the cortical hem and the CPe, Wnt gene expression is upregul

23 We identified interactions between the cortical hem, rich in Wingless-Int (WNT) proteins and bo

24 e dorsal telencephalic signaling center, the cortical hem.

25 alic and diencephalic signaling centers, the cortical hem and zona limitans intrathalamica (ZLI), are

26 alon, WNT2b expression appears to define the cortical hem, a dorsal signaling center previously chara

27 gions of the telencephalon (for example, the cortical hem (CH)) to populate the entire cortical surfa

28 in both Cajal-Retzius cells derived from the cortical hem that guide migration of progenitors and neu

29 tion of neocortical CR cells arises from the cortical hem.

30 sion might be a consequence of growth in the cortical hem (medial patterning center), which produces

31 t decreased Wnt3a and Lef1 expression in the cortical hem and adjacent hippocampal promordium and con

32 e, Wnt gene expression is upregulated in the cortical hem both before and just as the CPe begins to f

33 plexus in XtJ mice is due to defects in the cortical hem that include Wnt gene misregulation.

34 ping telencephalon Lmx1a is expressed in the cortical hem, and in its absence cortical hem progenitor

35 cal surface due to a migratory defect in the cortical hem, and is accompanied by upregulation of Ebf3

36 expression pattern of Frizzled10 mRNA in the cortical hem, dorsal thalamus and dorsal neural tube.

37 In the cortical hem, expression of LacZ mRNA was confined to th

38 rol the migration of CR cells arising in the cortical hem.

39 dial telencephalic structures, including the cortical hem, which normally expresses a number of Wnt m

40 of the Frizzled10 gene in order to mark the cortical hem (the most caudomedial edge of the telenceph

41 the previous finding that in these mice the cortical hem is expanded leading to increased production

42 source, positioned as a mirror image of the cortical hem, along the lateral margin of the cortical p

43 In the absence of Nf2, NPCs of the cortical hem, hippocampal primordium and neocortical pri

44 omolog 3) mutants results in the loss of the cortical hem-derived CR character but does not affect th

45 mutants, even prior to the formation of the cortical hem.

46 Effects of diminished BMP signaling on the cortical hem were at least partly responsible for these

47 In particular, the cortical hem, a region of high bone morphogenetic protei

48 the explants were evaluated by removing the cortical hem or presumptive extrahippocampal cortex from

49 whose normal expression is restricted to the cortical hem are completely absent in Gli3(Xt/Xt) embryo