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1 peptides melanocyte-stimulating hormone and corticotropin.
2 FSH)], with adrenocorticomelanotropic cells [corticotropin (ACTH) and alpha-melanotropin (alpha-MSH)]
3 in level and lack of stress- and cue-induced corticotropin and cortisol responses, higher anxiety, an
5 ects of cortisol metabolism: daily levels of corticotropin and cortisol; plasma cortisol clearance, m
6 retion of cortisol suppresses the release of corticotropin by pituitary corticotrophs, which results
8 ticotropin precursor proopiomelanocortin and corticotropin expression were assessed by means of a pol
10 lls: inositol polyphosphate-5-phosphatase A, corticotropin hormone precursor, ribosome biogenesis reg
18 and tumor DNA obtained from 33 patients with corticotropin-independent macronodular adrenal hyperplas
19 A axis dysregulation, marked by higher basal corticotropin level and lack of stress- and cue-induced
23 er in the patients than in controls, whereas corticotropin levels were lower (P<0.001 for both compar
27 d greater neutral, relaxed-state cortisol to corticotropin ratio (adrenal sensitivity) were each pred
29 gh an interaction between the stress hormone corticotropin releasing factor (CRF) and glutamate relea
34 of this study was to examine the ability of corticotropin releasing factor (CRF) or antibody to insu
36 icotine withdrawal was mediated by increased corticotropin releasing factor (CRF) receptor-1 expressi
38 lar nucleus (PVN) have been shown to inhibit corticotropin releasing factor (CRF) synthesis via GABA(
42 ontains a large number of neurons expressing corticotropin releasing factor (CRF), a neuropeptide tha
48 he transmembrane domains of the glucagon and corticotropin releasing factor 1 (CRF1) receptors to dev
50 oupled receptors, which bind peptides of the corticotropin releasing factor family and are key mediat
52 analysis showed significant upregulation of corticotropin releasing factor receptor 2 (CrfR2) in the
54 nvestigated here the interaction between the corticotropin releasing factor receptor type 1 (CRF1R) a
55 tuted pyridyl)pyrazolo[1,5-a]-1,3,5-triazine corticotropin releasing factor receptor-1 (CRF(1)) recep
57 in stress and appetite regulation, including corticotropin releasing factor, pro-opiomelanocortin B,
58 88-induced c-Fos activation were observed in corticotropin releasing factor-containing neurons of the
59 eus of the hypothalamus and primarily in non-corticotropin releasing factor-containing neurons of the
65 nt male and female offspring received either corticotropin releasing hormone (CRH) or saline intraven
68 ethylation of the cortisol-regulating genes, corticotropin releasing hormone (CRH; P=0.05) and glucoc
69 from the nucleus tractus solitarii (NTS) to corticotropin releasing hormone neurons in the paraventr
70 erone levels), and alleviated by antalarmin (corticotropin releasing hormone receptor 1 antagonist).
71 cluding the membrane progestin receptor, the corticotropin releasing hormone receptor, and the 5HT1a
73 oked robust upregulation of cholecystokinin, corticotropin releasing hormone, galanin, neuropeptide Y
76 were measured at baseline and in response to corticotropin-releasing factor (CRF) (0.5 microg kg(1))
79 mRNA was found to partially colocalize with corticotropin-releasing factor (CRF) and growth hormone-
81 laced on the neuropharmacological actions of corticotropin-releasing factor (CRF) and norepinephrine
84 s-induced release of neuromodulators such as corticotropin-releasing factor (CRF) can drive drug-depe
86 regulation of the central extrahypothalamic corticotropin-releasing factor (CRF) expression is assoc
89 hypersecretion of the stress neuromediator, corticotropin-releasing factor (CRF) has been implicated
90 rofiling of relevant PI cells identified the corticotropin-releasing factor (CRF) homolog, DH44, as a
91 ike ShA cocaine self-administration, reduced corticotropin-releasing factor (CRF) immunodensity in th
92 ed body of work indicates a crucial role for corticotropin-releasing factor (CRF) in neurobiological
93 termined the role of the stress neurohormone corticotropin-releasing factor (CRF) in stress-induced b
94 ed on previous work hypothesizing a role for corticotropin-releasing factor (CRF) in the IC during cr
95 lores the relationship between dynorphin and corticotropin-releasing factor (CRF) in the induction of
96 bout the distribution of the stress hormone, corticotropin-releasing factor (CRF) in the mouse brain.
98 literature suggests that catecholamines and corticotropin-releasing factor (CRF) interact in a seria
104 and anxiety and activates a subpopulation of corticotropin-releasing factor (CRF) neurons in the bed
105 cohol intake specifically recruited GABA and corticotropin-releasing factor (CRF) neurons in the mPFC
106 the relationship between corticosterone and corticotropin-releasing factor (CRF) on both beta-amyloi
107 ed the effect of an intravenous injection of corticotropin-releasing factor (CRF) on fructose malabso
108 nced fear memory but did not increase either corticotropin-releasing factor (CRF) or corticosterone.
113 duction and Abeta elevation are dependent on corticotropin-releasing factor (CRF) receptor 1 signalin
116 ife social isolation increases the levels of corticotropin-releasing factor (CRF) receptors in the se
119 induced relapse through alterations in brain corticotropin-releasing factor (CRF) regulation of neuro
124 f neonatal amygdala (Neo-A) lesions on brain corticotropin-releasing factor (CRF) systems and hypotha
128 nsistent with this, the CEA highly expresses corticotropin-releasing factor (CRF), an important modul
129 (Dh44), a neuropeptide related to vertebrate corticotropin-releasing factor (CRF), and its receptor,
131 to the BNSTDL, is thought to communicate via corticotropin-releasing factor (CRF), but studies have y
134 ological studies indicate the involvement of corticotropin-releasing factor (CRF), noradrenaline, dop
139 ral amygdala noradrenergic substrates [via a corticotropin-releasing factor (CRF)-dependent mechanism
140 allenge has been shown previously to cause a corticotropin-releasing factor (CRF)-mediated increase i
148 This study tested the hypothesis that the corticotropin-releasing factor (CRF1) antagonist GSK5616
149 ist (eticlopride), D2R agonist (quinpirole), corticotropin-releasing factor 1 (CRF1) antagonist (anta
150 urthermore, pharmacologic inhibition (with a corticotropin-releasing factor 1 receptor antagonist) of
151 t of brain stress neurotransmitters, such as corticotropin-releasing factor and dynorphin, in the neu
152 alcohol drinking by increased expression of corticotropin-releasing factor and its feedback regulati
153 ed with brain region-specific alterations of corticotropin-releasing factor expression and promoter m
156 ephalin, thyrothropin-releasing hormone, and corticotropin-releasing factor immunoreactive cells in t
159 s in the anterior hypothalamus that may gate corticotropin-releasing factor output from the amygdala
160 ss, the physiological consequence of central corticotropin-releasing factor receptor (CRF-R) activati
161 viously reported differential involvement of corticotropin-releasing factor receptor (CRFR) 1 and 2 i
163 In addition, we examined the role of the corticotropin-releasing factor receptor 1 (CRF(1)) in th
164 We aimed to characterize the effects of the corticotropin-releasing factor receptor 1 (CRF-R1) antag
165 noradrenergic (NE) receptors (alpha1) via a corticotropin-releasing factor receptor 1 (CRF-R1)-depen
166 rial evaluating the efficacy of GSK561679, a corticotropin-releasing factor receptor 1 (CRF1 receptor
168 Similarly to what has been observed for the corticotropin-releasing factor receptor 1 (CRFR1), SAP97
169 me proliferator-activated receptor gamma and corticotropin-releasing factor receptor 1 were notable e
170 ecifically activated by either neurokinin I, corticotropin-releasing factor receptor 1, or dopamine D
171 mutants with constitutive activation of the corticotropin-releasing factor receptor family homologue
172 d, we took the CRF(2(a))R and the homologous corticotropin-releasing factor receptor type 1 (CRF(1)R)
173 esent study investigated whether blockade of corticotropin-releasing factor receptor type 1 (CRF-R1)
174 n reflect reductions in anandamide driven by corticotropin-releasing factor receptor type 1 (CRF1) po
175 we investigated interactions of the class B corticotropin-releasing factor receptor type 1 (CRF1R) w
177 ular membrane compartments, we show that the corticotropin-releasing factor receptor type 1 has a spe
178 ure of the transmembrane domain of the human corticotropin-releasing factor receptor type 1 in comple
181 vation of the central stress response, while corticotropin-releasing factor receptor type 2 (CRFR2) h
183 eviously, we observed abnormal expression of corticotropin-releasing factor receptor type 2 (CRFR2) t
186 n in the BNST is unaffected by alpha1-AR and corticotropin-releasing factor receptor-1 (CRFR(1)) anta
187 Effects on attention were attenuated by the corticotropin-releasing factor receptor-1 antagonist ant
191 ry-adrenal axis), (4) the (gastrointestinal) corticotropin-releasing factor system, and (5) the intes
195 icated that repeated social stress decreased corticotropin-releasing factor type 1 receptor and incre
197 disrupts this LTCC-based mechanism; instead, corticotropin-releasing factor type 1 receptors (CRF1s)
198 disrupts this LTCC-based mechanism; instead, corticotropin-releasing factor type 1 receptors (CRF1s)
200 demonstrated that the mechanism involved the corticotropin-releasing factor type 2 receptor, cAMP ele
201 n the amygdala, which required activation of corticotropin-releasing factor type-1 (CRF-R1) receptors
202 cial behavior (especially neuropeptide Y and corticotropin-releasing factor) are modulated by alcohol
204 tuitary-adrenal axis, including signaling by corticotropin-releasing factor, in the pathophysiology o
205 w stress interacts with the neuromodulators, corticotropin-releasing factor, norepinephrine, dopamine
206 ess effect by counteracting the functions of corticotropin-releasing factor, the primary stress-media
207 peptides (ghrelin, nesfatin-1, somatostatin, corticotropin-releasing factor, thyrotropin-releasing ho
208 known as maternal aggression) is impaired by corticotropin-releasing factor-(CRF) related peptides, b
209 s was identified as potent and orally active corticotropin-releasing factor-1 (CRF(1)) receptor antag
210 ctive withdrawal-like state characterized by corticotropin-releasing factor-1 (CRF(1)) receptor antag
211 rmittent access to palatable food results in corticotropin-releasing factor-1 (CRF1) receptor antagon
214 luding those that encode the stress hormones corticotropin-releasing hormone (CRH) and adrenocorticot
216 n-33 (IL-33), and stress molecules including corticotropin-releasing hormone (CRH) and neurotensin (N
217 s been postulated that altered expression of corticotropin-releasing hormone (CRH) can at least parti
218 larval zebrafish with transgenically labeled corticotropin-releasing hormone (CRH) cells, which repre
219 employed viral-genetic approaches to reduce corticotropin-releasing hormone (Crh) expression in the
220 tress promotes secretion of the neuropeptide corticotropin-releasing hormone (CRH) from hippocampal i
221 axis initiates the production and release of corticotropin-releasing hormone (CRH) from the paraventr
222 activity for the suppression of hypothalamic corticotropin-releasing hormone (CRH) gene expression an
223 of the expression of the stress neurohormone corticotropin-releasing hormone (CRH) in hypothalamic ne
224 nstrate that a cluster of neurons expressing corticotropin-releasing hormone (Crh) in the pontine mic
230 affects excitatory and inhibitory inputs to corticotropin-releasing hormone (CRH) neurons in the hyp
232 tical areas transmit signals to hypothalamic corticotropin-releasing hormone (CRH) neurons, which con
233 augments excitatory synaptic strength in PVN corticotropin-releasing hormone (CRH) neurons, with GLP-
234 el synergistic actions of corticosterone and corticotropin-releasing hormone (CRH) on synaptic physio
235 ing hormone, oxytocin, arginine vasopressin, corticotropin-releasing hormone (CRH) or thyrotropin-rel
236 ress, adrenal corticosterone and hippocampal corticotropin-releasing hormone (CRH) permeate memory-fo
237 g-standing paradigm posits that hypothalamic corticotropin-releasing hormone (CRH) regulates neuroend
240 In addition, increased activation of the corticotropin-releasing hormone (CRH) system within the
241 working memory (WM) deficits; changes to the corticotropin-releasing hormone (CRH) system; and struct
242 e production and release of the neuropeptide corticotropin-releasing hormone (CRH) within the hippoca
243 n the underlying mechanisms, but the role of corticotropin-releasing hormone (CRH), a hypothalamic ho
247 nals were collected and processed to measure corticotropin-releasing hormone (CRH), urocortin (Ucn),
248 activities by stimulating the expression of corticotropin-releasing hormone (CRH), urocortin, proopi
249 multilabeled for vasotocin, mesotocin (MT), corticotropin-releasing hormone (CRH), vasoactive intest
250 ormone 44 (Dh44), a homolog of the mammalian corticotropin-releasing hormone (CRH), were specifically
251 ticoids and the stress-released neuropeptide corticotropin-releasing hormone (CRH), which influence t
252 evious studies have described the effects of corticotropin-releasing hormone (CRH), which is released
253 he adult brain, we have virally traced local corticotropin-releasing hormone (CRH)-expressing inhibit
254 noreactive boutons in apposition to both the corticotropin-releasing hormone (CRH)-immunoreactive cel
259 found that the rs28365143 variant within the corticotropin-releasing hormone binding protein (CRHBP)
264 e other ligand-binding site defined--for the corticotropin-releasing hormone receptor 1 (CRF1R)--whic
268 ment interaction in which a haplotype in the corticotropin-releasing hormone receptor 1 gene (CRHR1)
269 elch-like protein 2)), chromosome 17 (CRHR1 (corticotropin-releasing hormone receptor 1) and MAPT (mi
271 5-2 muM) for 6 hours significantly increases corticotropin-releasing hormone receptor-1 (CRHR-1) mRNA
272 found a significant three-way interaction on corticotropin-releasing hormone receptor-1 (Crhr1) gene
273 bellar Purkinje cells, and co-localized with corticotropin-releasing hormone receptors in the latter.
275 in both the initial and replication samples: corticotropin-releasing hormone signaling, cardiac beta-
276 l enrichment analyses revealed enrichment of corticotropin-releasing hormone signaling, GNRH signalin
277 y outcomes, including repeated dexamethasone-corticotropin-releasing hormone tests, and psychiatric r
278 a indicate that genetic variation within the corticotropin-releasing hormone type 1 receptor gene (CR
280 way in rat paraventricular hypothalamic CRH (corticotropin-releasing hormone) neuroendocrine neurons
282 ernal blood (i.e., C-reactive protein (CRP), corticotropin-releasing hormone, and cytokines) were com
283 at several peptide markers (cholecystokinin, corticotropin-releasing hormone, and tachykinin 1) label
284 the pathogenesis of IBD include substance P, corticotropin-releasing hormone, neurotensin, and vasoac
285 not GABAergic, and do not express oxytocin, corticotropin-releasing hormone, vasopressin, or prodyno
287 al raphe-originating serotonergic control of corticotropin-releasing hormone-mediated excitation of t
288 refrontal cortex restrains the amygdala, the corticotropin-releasing hormone/hypothalamic-pituitary-a
292 We evaluated adrenal function using short corticotropin stimulation test in 157 episodes of gastro
293 We evaluated adrenal function using short corticotropin stimulation test in patients with cirrhosi
300 ushing's syndrome appears to be regulated by corticotropin, which is produced by a subpopulation of s
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