ライフサイエンスコーパス: cosegregation

1 mily members to establish genotype-phenotype cosegregation.

2 oncarriers to establish clinical and genetic cosegregation.

3 mmetric self-renewal and immortal DNA strand cosegregation.

4 mmetric self-renewal and immortal DNA strand cosegregation.

5 ly coupled by physical linkage and resulting cosegregation.

6 y is not possible without data demonstrating cosegregation.

7 tentially disease-causing gene variants with cosegregation, a novel hyperpolarization-activated cycli

8 Limited phylogenetic cosegregation among hepatoviruses and their hosts and re

9 lysis and confirmed by Sanger sequencing and cosegregation analyses.

10 Identification of a second mutant allele and cosegregation analysis confirmed correlation with the mu

11 Cosegregation analysis in each available family showed t

12 genes and to evaluate disease penetrance by cosegregation analysis in family members.

13 t genomic sequencing and, where possible, by cosegregation analysis in the families of the index case

14 fied >500 seedling-lethal mutants, completed cosegregation analysis of the insertion and the lethal p

15 Cosegregation analysis revealed 5.5- and 2.4-kb Mu1-hybr

16 ed in an active Mutator (Mu) population, and cosegregation analysis revealed that it arose from a Mu3

17 Cosegregation analysis showed that the functional y1 gen

18 nts were confirmed by Sanger sequencing, and cosegregation analysis was performed in families, follow

19 Random marker genome screening and cosegregation analysis were performed on F2 hybrids deri

20 The authors were unable to determine through cosegregation analysis whether three other changes encou

21 ix additional affected family members showed cosegregation and a maximum LOD score of 3.6.

22 Our sequencing, cosegregation and rescue results indicate that suc encod

23 MP guidelines is the lack of a definition of cosegregation as criteria for pathogenicity classificati

24 Further cosegregation, complementation, and comparative analyses

25 n small families and sporadic cases, wherein cosegregation could not be established.

26 Cosegregation data differ from many other types of patho

27 evolution, including frequent PB2-PB1-PA-NP cosegregation during avian influenza reassortment.

28 t of LD, suggesting the need to model LD and cosegregation explicitly.

29 We evaluated deleterious variants for cosegregation in families and assessed clinical characte

30 own inconsistent results; there is a lack of cosegregation in some pedigrees and an unexpectedly high

31 Sanger sequencing confirmed complete cosegregation in the family.

32 Cosegregation information also declines with increasing

33 Cosegregation information from half sibs contributes lit

34 ese analyses reveal that immortal DNA strand cosegregation is also regulated by IMPDH and confirm the

35 al implicit precept that immortal DNA strand cosegregation is specific to cells undergoing asymmetric

36 its confounded effect on the pattern of gene cosegregation, it complicates linkage analysis and map c

37 For tightly linked loci, cosegregation may lead to nonrandom associations between

38 However, cosegregation of a mutant allele with the disease phenot

39 erged that suggested at least some degree of cosegregation of ADHD and learning disabilities in famil

40 sk for DESR and cannot determine whether the cosegregation of ADHD in DESR within families is a resul

41 he existence of immortal DNA strands and the cosegregation of chromosomes that bear them.

42 ed a second, ethnically distinct, family for cosegregation of disease with markers from the linked re

43 Cosegregation of epilepsy and deafness was not observed

44 Reports proposing cosegregation of genes found on the X chromosome with bi

45 on suppression over large genomic tracts and cosegregation of genes of various functions, not necessa

46 latedness, and attempts are made to identify cosegregation of genetic markers and phenotypes within t

47 ons-sex concordance in sib pairs with HD and cosegregation of HD and LWD-impelled a test of the hypot

48 n bipolar affective disorder (BPAD) revealed cosegregation of high numbers of EvC and Bipolar I (BPI)

49 bsequent lineage restrictions, an unexpected cosegregation of lymphoid and myeloid gene expression an

50 Cosegregation of MNGIE with a single chromosomal region

51 In each of these families there is complete cosegregation of mood disorder with a segment of chromos

52 this phenomenon occurs involves preferential cosegregation of nonparental chromatids of both chromoso

53 eviously linked to schizophrenia through the cosegregation of oculocutaneous albinism with psychosis

54 We report the cosegregation of point mutations in the neuroserpin gene

55 Cosegregation of profound, congenital deafness with mark

56 This is unfortunate, because cosegregation of rare variation and disease status in fa

57 There was a strong cosegregation of SFB positivity and diabetes protection

58 regation, since deletion of clp1/flp1 causes cosegregation of sister chromatids, when sister kinetoch

59 Cosegregation of template DNA during mitosis is one mech

60 1ADE2 inserted into a YAC were identified by cosegregation of the ADE2 gene with the URA3-marked YAC.

61 inkage analysis of F2(SxR) male rats detects cosegregation of the alpha1 Na,K-ATPase locus with salt-

62 n F2 and two backcross populations indicated cosegregation of the augmented orf107 and urf209 process

63 The results clearly demonstrate cosegregation of the branch-point mutation with the CCA

64 did the seeds of the F1 hybrids, indicating cosegregation of the genes for rosette size and the germ

65 Studies of human-mouse chimeras revealed cosegregation of the high (36)Cl(-) transport phenotype

66 forbold locus-specific haplotyping to detect cosegregation of the locus haplotype with the phenotype,

67 Complete cosegregation of the mutation with reduced free protein

68 milial PA, whole-exome sequencing identified cosegregation of the PA phenotype with the heterozygous

69 integrated into the nuclear genome, (2) show cosegregation of the resistance phenotype with the intro

70 The cosegregation of the traits is attributed to tight linka

71 s can be combined with data from analysis of cosegregation of the UCVs with cancer, co-occurrence of

72 D is prevented by missing data demonstrating cosegregation of the variants and incomplete knowledge a

73 In addition, the cosegregation of these phenotypes allows us to postulate

74 The significance of the cosegregation of this phenotype and B-1a cell expansion

75 Cosegregation of this region with disease in different e

76 associated genes and the ability to test for cosegregation of variants with disease through extended

77 Cosegregations resulting in significant increases of T2D

78 Cosegregation studies could not be performed on the pati

79 limits their number and immortal DNA strand cosegregation that limits their accumulation of mutation

80 and additive-genetic relationships, but also cosegregation to capture relationships at QTL.

81 bers were genotyped by Sanger sequencing and cosegregation was analyzed.

82 Template DNA cosegregation was enhanced by cell-cell contact.

83 Perfect cosegregation was observed for broccoli and cauliflower

84 Moreover, oligogenic cosegregation was suggestive for complex inheritance and

85 Testing of the CMM abundances for cosegregation with 530 fully informative SNP markers ide

86 s and emphasizes the importance of observing cosegregation with deafness in large families to confirm

87 subjects, and no evidence for association or cosegregation with disease in family-based analyses.

88 and, in a subset of probands, an analysis of cosegregation with disease in pedigrees.

89 ino acid position in multiple pedigrees, and cosegregation with disease in these pedigrees provide ev

90 g studies because they provide a way to test cosegregation with disease of variants that are too rare

91 The cosegregation with hypertension of an impaired D1 recept

92 All analyses excluded CYP19 cosegregation with PCOS, demonstrating that this locus i

93 Mutations were examined for familial cosegregation with phenotype and presence or absence in

94 cluded from the EDA locus by the lack of its cosegregation with polymorphic markers flanking the EDA

95 ers of 188 HPC families and tested for their cosegregation with prostate cancer.

96 ns, were initially identified based on their cosegregation with S alleles.

97 tation can be observed in many relatives and cosegregation with TG can be tested.

98 med transmission of the PIEZO1 mutations and cosegregation with the disease phenotype in all affected

99 Candidate variants were tested for cosegregation with the disease.

100 were screened and new variants assessed for cosegregation with the disease.

101 edicted to be damaging were investigated for cosegregation with the low HDL-C trait in the entire ext

102 c mutations and two of which exhibited exact cosegregation with the phenotype of interest.

103 Genetic mapping in pea demonstrated cosegregation with the yellow/green cotyledon polymorphi