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   1 vation goals from LCC partners for the least cost.                                                   
     2 y completely with little added computational cost.                                                   
     3  statistical significance without increasing cost.                                                   
     4 nsities, long-term stability, safety and low cost.                                                   
     5 energy storage applications owing to the low cost.                                                   
     6 -conceived infants, suggesting an epigenetic cost.                                                   
     7 ly increase surgical time and, consequently, cost.                                                   
     8 f wet sludge volume) and consequent disposal cost.                                                   
     9 ities to reduce the generally high treatment costs.                                                  
    10 nd are associated with increased health care costs.                                                  
    11 ting dose may influence patient outcomes and costs.                                                  
    12 y achieve a more desirable allocation of EEC costs.                                                  
    13 ancer, whereas NMSC impacted only outpatient costs.                                                  
    14 ited States and the associated public sector costs.                                                  
    15  fewer hospitalizations and lower healthcare costs.                                                  
    16  could influence U.S. air quality and health costs.                                                  
    17 nced wide adoption given its high associated costs.                                                  
    18 ur primary outcome was 90-day total hospital costs.                                                  
    19 resulting in high economic and environmental costs.                                                  
    20 lity of available data, they come with heavy costs.                                                  
    21 savings were estimated based on our internal costs.                                                  
    22 oposition: better quality of care with lower costs.                                                  
    23 ulties, process complexities and prohibitive costs.                                                  
    24 sequent hospitalizations and lower follow-up costs.                                                  
    25  benefits of building new bonds outweigh the costs.                                                  
    26 substantial patient, caregiver, and economic costs.                                                  
    27 ather a single movement that optimizes motor costs.                                                  
    28 ospitals based on time-driven activity-based costing.                                                
  
    30 those who were opioid-naive) had 9.2% higher costs [95% confidence interval (CI) 2.8%-15.6%; adjusted
  
  
  
    34 c diagnostics first emerged in 2007 as a low-cost alternative to conventional laboratory testing, wit
  
    36 nowledge, the first estimates of the fitness cost and benefit associated with resistance of the gonoc
    37    Most importantly, these sensors offer low-cost and disposable detection platforms for real-world a
  
  
  
    41 ic technology aims to reduce the fabrication cost and improve the power conversion efficiency (PCE) o
    42 y hampered by the relatively high production cost and low efficiency of current thermoelectric materi
  
    44 ing technology has recently emerged as a low-cost and practical method for fabrication of flexible an
  
  
    47 ry, but the mechanism by which they increase cost and the categories of care that drive this increase
  
  
  
  
    52 ased evolutionary simulations to incorporate costs and benefits of two coevolving costly traits: coop
  
    54 e regulatory design will minimize compliance costs and HEC tradeoffs by regulating air, water, and so
  
  
  
    58  high sampling and retention efficiency, low costs, and applicability for diverse downstream microbio
    59 ent sustained virological response rates, LT costs, and baseline Model for End-Stage Liver Disease sc
  
  
    62 rvival, quality-adjusted life years (QALYs), costs, and resulting budget impact between ECHO and non-
  
  
  
    66 tly reduce both mortality and the healthcare costs associated with bacterial infections, including th
  
  
    69 of viruses to their hosts, we enumerated the costs associated with two very distinct but representati
  
    71 mputational mechanisms underlying subjective cost-benefit valuation across different domains of effor
  
    73   Comprehensive estimates that decompose the cost by different stakeholders (as proposed in our frame
    74 cteristics and asking about donation-related cost concerns prior to donation might allow transplant c
  
    76 onfirmation with clinic records, and lack of cost data from other case-finding approaches commonly us
  
    78 cal biosensor for on-step, sensitive and low cost detection of beta-lactoglobulin (beta-LG) milk prot
  
  
  
    82 iveness ratio (ICER = difference in lifetime costs/difference in lifetime health outcomes) to compare
    83 hs could have been avoided had there been no cost differential between the median-priced and minimum-
    84 cause their detection is compatible with low-cost disposables and because application of a magnetic f
    85 o 18 y of nursing home use and out-of-pocket costs drawn from the Health and Retirement Study, a long
    86 ting hydraulic failure, (2) increases carbon costs during periods of carbon starvation, and (3) promo
    87 ork focuses on the development of a fast and cost effective method based on Laser Induced Breakdown S
  
    89 h terrestrial restoration typically the most cost-effective action; and (4) land protection should be
  
    91 stage osteoarthritis of the hip and knee are cost-effective and demonstrate significant clinical impr
    92 vides a new material platform to introduce a cost-effective and efficient ointment option after under
  
  
    95 The German health insurance system is not as cost-effective as in some of Germany's neighbouring coun
    96  Adding surveillance to FIT screening is not cost-effective based on the Dutch ICER threshold and sub
  
    98 y incorporating innovative technologies into cost-effective diagnostic methods that can mitigate the 
    99 rein, a novel approach for rapid, simple and cost-effective discrimination/clustering, as a tool to a
  
  
  
  
  
   105  and high on/off ratios paving the way for a cost-effective high power device paradigm on an Si CMOS 
   106 ective if the surgery cost less than $66 and cost-effective if less than $398 (based on the World Ban
   107 al hydrocelectomy would be classed as highly cost-effective if the surgery cost less than $66 and cos
   108 ine and antibody strategies are likely to be cost-effective if they can be priced below around pound2
   109 adjusted life-year range frequently cited as cost-effective in the United States for eyes presenting 
   110 ans (4D-CTs) have emerged as an accurate and cost-effective initial localization study for patients w
  
  
   113 ral flow assay (LFA) can provide a rapid and cost-effective means to detect targets in situ; however,
   114 signs that permit on-site diagnostics with a cost-effective mobile-phone-based multimodal microscope.
   115 tients regardless of fibrosis stage, but was cost-effective only for patients with F3 fibrosis; our r
  
  
   118 ing to their reproducibility, stability, and cost-effective production, the recombinant variable doma
   119    Conclusion Specialized surveillance was a cost-effective strategy for the management of individual
   120 ameters, the test option would still be more cost-effective than the no-test option (less than euro30
   121 ction, standardized reference reagents are a cost-effective way to maintain robustness and reproducib
  
   123 whether low-risk elderly vaccination remains cost-effective, driven by the choice of cost-effectivene
  
   125 ared spectrum can be improved by introducing cost-effective, rapid, and high-throughput fabrication t
  
  
  
   129 on oF FactORs ImpacTing CLinical Outcome and Cost EffectiveneSS of the S-ICD) registry is collecting 
  
  
  
  
  
  
   136 atment versus deferred DAA treatment using a cost-effectiveness decision analysis model to estimate i
  
   138 clinical psychology, epidemiology, genomics, cost-effectiveness modeling, pathology, bioethics, and p
  
  
   141    To use the trial results to determine the cost-effectiveness of a PCSK9i and statin treatment stra
   142  evaluate the additional benefit in terms of cost-effectiveness of colonoscopy surveillance in a scre
   143  in lifetime health outcomes) to compare the cost-effectiveness of CXL versus conventional management
  
   145 am coastal marine ecosystem and contrast the cost-effectiveness of marine- and land-based conservatio
  
  
  
  
  
  
   152 tal costs of $7,435, yielding an incremental cost-effectiveness ratio (ICER) of $94,917/QALY gained. 
  
   154 ision analysis model to estimate incremental cost-effectiveness ratios (cost per quality-adjusted lif
  
  
  
  
   159     Over a 40 year time horizon, incremental cost-effectiveness ratios were pound22 201 (95% credible
  
  
  
   163 if less than $398 (based on the World Bank's cost-effectiveness thresholds for low income countries).
   164    The primary outcomes were the incremental cost-effectiveness values ($/QALY) for each moisturizer 
  
   166 racterize an industry-grade CMOS camera as a cost-efficient alternative to commonly used scientific c
  
  
   169 help us quantify individual variation in the costs experienced from social and ecological factors, an
  
   171 tions are associated with increased hospital costs following major surgery, but the mechanism by whic
  
  
   174 lies by volume, and therefore, also by total cost for eye care providers compared with all other prov
  
   176 Grade B or C) and hospital-related inpatient costs for 90 days following PD, converted to 2014 $USD. 
  
   178 ed to lower cumulative and annual healthcare costs for those in favorable cardiovascular health (P<0.
   179 racterize Medicare and patient out-of-pocket costs for topical steroids, and to model potential savin
   180 tinal images), a response noise model, and a cost function, AMA returns the filters (i.e. receptive f
   181   Concern about its associated morbidity and cost has led to a large body of research that has been s
   182 e, easy transportability, and relatively low cost have encouraged physicians to use these devices for
   183 systems; procurement and distribution of low-cost, high-quality antifungal medicines; and concomitant
  
  
   186 cer had the largest inpatient and outpatient cost impacts per case, followed by "other" cancer, where
   187   Quality-adjusted life-years (QALYs), total costs (in US dollars adjusted to 2015-year values using 
   188 vices (economic impact), whereas externality costs include effects outside the economic system (e.g.,
  
  
  
   192 nd in contest 2 for the experienced animals, costs increased with loser RHP and where unaffected by w
   193 nd trastuzumab followed a similar pattern in cost increases over time, and the inflation-adjusted mon
  
   195 y reversible, as well as the high healthcare costs inherent in device use, a clear understanding of t
   196 d thin phase-conjugate nanostructures on low-cost ink coated glass substrates through a facile and fl
  
   198 s, and only a small fraction of their higher cost is likely to be recovered by prevention of cardiova
  
   200 tanding of the clinical benefits relative to costs is essential for both appropriate clinical use and
  
   202 t DNA sequencing technologies and decreasing costs, large gene expression datasets are being generate
   203 ssed as highly cost-effective if the surgery cost less than $66 and cost-effective if less than $398 
  
  
   206 attice-free cell list, with a time and space cost linearly proportional to the number of particles in
   207 g are poorly understood, the extent to which cost may be a barrier to monitoring in different setting
   208  included countries' mean patient TB-related costs, mean household income, mean cash transfers, and e
   209     Here, we describe a highly parallel, low-cost method for measuring the average rate and substrate
  
  
   212 The disposable, efficient, sensitive and low-cost non-enzymatic PAD has great potential for the devel
   213 s compared with no surgery at an incremental cost of $30747, yielding an unfavorable ICER of $154684 
  
  
   216 tion between catchments and lakes but at the cost of biogeochemical changes that release stored conta
   217 s suggest that long-term population size and cost of complexity drive the evolution of the DFE, with 
   218 roposed in our framework), that consider the cost of epidemic years, and that account for productivit
  
  
  
  
  
   224 pulations but provides this advantage at the cost of modestly promoting the risk of autoimmunity.    
  
  
  
  
  
  
  
   232 sociated with the lack of stability and high cost of the biological recognition element (enzyme).    
   233  The cost for the cohort, which included the cost of the test, subsequent treatments received, and he
   234 inants of water scarcity are found to be the cost of transporting and storing water, society's instit
  
  
  
  
   239 ted with QALY gains of 0.078 and incremental costs of $7,435, yielding an incremental cost-effectiven
   240 do so by considering the social benefits and costs of confrontational types of proactive policing, su
   241 ysis was one of the first to incorporate the costs of generic ZA and one of the first independent CE 
  
   243 resource complexity strongly buffers fitness costs of mutations, and that anabolic rather than catabo
   244 N) status is inversely related to increasing costs of N acquisition with increasing soil carbon, adeq
   245 load that can accurately predict the fitness costs of passengers in cell lines and in human breast ca
   246 ialization may be reinforced by the elevated costs of prey switching, thus promoting the process of r
  
  
  
  
   251 imate incremental cost-effectiveness ratios (cost per quality-adjusted life year gained) from the soc
   252 Q) for 2010 to calculate the hospitalization costs per year attributed to misdiagnosed lower extremit
   253   Here, we present Seq-Well, a portable, low-cost platform for massively parallel single-cell RNA-seq
   254 Our second advance: the development of a low cost, portable red cell analyzer to measure these parame
  
   256 lations remained robust to variation in test cost, prevalence of HSV infection, and random variation 
  
   258  to address these limitations due to its low-cost, rapid, and simple features, but the poor analytica
  
   260  per day per reactor, demanding a 5000x unit cost reduction to  $0.20, and is a critical, key challen
   261 ver time, and the inflation-adjusted monthly costs rose since approval by 49% and 44%, respectively. 
  
  
  
  
   266 nnish Asthma Program resulted in significant cost savings at both the societal and patient levels dur
   267  for mental health care may lead not only to cost savings but also to negative downstream consequence
  
  
  
   271 were employed to determine significance, and cost savings were estimated based on our internal costs.
  
   273 the copoly(DMA-NAS-MAPS) microarray is a low-cost, self-producible alternative to the commercial Immu
  
   275 couraging for the further development of low-cost, Si wafer-based IREs for electrochemical ATR-SEIRAS
  
   277 tion plants account for half their operating costs, so alternative, lower energy approaches are equal
   278 , a negative relation between winner RHP and costs suggested mutual assessment during the pre-escalat
   279 dy offers design insights for developing low-cost surface microfluidic mixing devices on open substra
  
   281 ons and do not take into account free energy costs that may be associated with structural rearrangeme
   282 tural engineering approach for producing low-cost titanium alloys with exceptional fatigue strength v
  
  
  
   286 epatitis C virus (HCV) infection, because of cost, treatment is often denied until liver fibrosis has
   287 2,000 (95% CI: 5,200, 46,000) infections and cost US$18,000 (95% CI: US$14,000, US$24,000) per QALY g
   288 5,000 (95% CI: 8,900, 43,000) infections and cost US$25,000 (95% CI: US$7,000, US$76,000) per QALY ga
   289 6,700 (95% CI: 1,200, 16,000) infections and cost US$27,000 (95% CI: US$15,000, US$48,000) per QALY g
   290 up to 37,000 (22,000, 58,000) infections and cost US$300,000 (95% CI: US$162,000, US$667,000) per QAL
  
  
  
  
  
  
  
  
  
   300 s to commit to cooperate (proposers) incur a cost, while their co-players are not necessarily require
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