ライフサイエンスコーパス: cote

1 y with the outer coat morphogenetic protein, CotE.

2 at is dependent on the morphogenetic protein CotE.

3 in coat surface morphology: CotA, CotB, and CotE.

4 -amino-acid region in the N-terminal half of CotE.

5 Key to this is CotE, a protein displayed on the spore surface and carry

6 pores of a strain with mutations in both the cotE and gerE genes, which encode proteins involved in c

7 changes in the C-terminal 23 amino acids of CotE and in the remainder of the protein have different

8 dependent on the coat morphogenetic proteins CotE and SpoIVA.

9 suggest that: (i) most interactions between CotE and the coat proteins assembled under CotE control

10 expression of morphogenetic proteins SpoIVA, CotE, and SpoVID.

11 ion of three morphogenetic proteins: SpoIVA, CotE, and SpoVID.

12 A 181-amino-acid coat protein called CotE assembles into the coat early in spore formation an

13 D that is essential for the interaction with CotE but dispensable for the interaction with SafA.

14 sembled under CotE control take place at the CotE C-terminus; (ii) an internal region of CotE connect

15 To understand how CotE carries out its role in coat morphogenesis, we subj

16 CotE C-terminus; (ii) an internal region of CotE connects it with the forespore surface; and (iii) i

17 n CotE and the coat proteins assembled under CotE control take place at the CotE C-terminus; (ii) an

18 B. subtilis coat proteins (CotY, CotE, CotV and CotW) expressed in Escherichia coli can a

19 ions, the Republic of South Africa (RSA) and Cote d'Ivoire (CI).

20 untries: Burkina Faso (January-August 2013), Cote d'Ivoire (March 2015-February 2016), The Gambia (Ju

21 of bDNA analysis of human blood samples from Cote d'Ivoire (n = 50) showed excellent agreement with t

22 ce = 2.2%; 1,000 patients treated/year), and Cote d'Ivoire (prevalence = 3%; 150 patients treated/yea

23 w-borne hantavirus infections in humans from Cote d'Ivoire and Gabon.

24 ces of antepartum depression in mothers from Cote d'Ivoire and Ghana were 28.3% and 26.3%, respective

25 d of Bioko (in Equatorial Guinea), Cameroon, Cote d'Ivoire and Sierra Leone.

26 ost-effective, and should become standard in Cote d'Ivoire and similar settings.

27 molecular epidemiology of HIV-1 CRF02_AG in Cote d'Ivoire and West Africa, which could be important

28 nes, we show that the ebolaviruses Zaire and Cote d'Ivoire are strongly dependent on cathepsin B, whi

29 y of the urban populations in The Gambia and Cote d'Ivoire became especially clear during the 2007-20

30 om surveys undertaken in four communities in Cote d'Ivoire between March, 1997, and September, 2010.

31 bolavirus (SEBOV), Zaire ebolavirus (ZEBOV), Cote d'Ivoire ebolavirus (CIEBOV), and Marburgvirus (MAR

32 Chimpanzees from the Tai forest of Cote d'Ivoire produce unintentional flaked stone assembl

33 ere were 654 mother/child dyads in Ghana and Cote d'Ivoire that were enrolled in a prospective birth

34 eatment strategies for a cohort of adults in Cote d'Ivoire who were infected with the human immunodef

35 We assessed cost-effectiveness relative to Cote d'Ivoire's 2013 per capita GDP ($1500).

36 d 12 months postpartum were 11.8% and 16.1% (Cote d'Ivoire) and 8.9% and 7.2% (Ghana).

37 avirus surveillance projects in Cameroon and Cote d'Ivoire, 2 fecal samples collected from 2 children

38 chimpanzee (Pan troglodytes verus) sites in Cote d'Ivoire, aged between 4.3 and 1.3 thousand years a

39 The rice sectors in The Gambia, Cote d'Ivoire, and Mali are scrutinized as well as cotto

40 4 different species are known: Zaire, Sudan, Cote d'Ivoire, and Reston ebolavirus.

41 rom the other pathogenic subtypes, Sudan and Cote d'Ivoire, as well as from Reston, a strain thought

42 In Thailand and Cote d'Ivoire, focusing treatment only on F3-F4 patients

43 meningitis belt (Benin, Burkina Faso, Chad, Cote d'Ivoire, Ghana, Mali, Niger, Nigeria, and Togo) co

44 Influenza Centers from 5 countries-Cameroon, Cote d'Ivoire, Madagascar, Niger, and Senegal--collected

45 , Chad, Democratic Republic of Congo, Ghana, Cote d'Ivoire, Mali, Niger, Nigeria, Togo).

46 various treatment-as-prevention scenarios in Cote d'Ivoire, one of the countries with the highest HIV

47 obust across the four diverse communities in Cote d'Ivoire, only one of which would have received ann

48 s-sectional study in Burkina Faso, Cameroon, Cote d'Ivoire, Senegal, Togo, Thailand, and Vietnam to a

49 ild-born captive chimpanzees in Cameroon and Cote d'Ivoire, shows that P. reichenowi is a geographica

50 o started ART in four scale-up programmes in Cote d'Ivoire, South Africa, and Malawi from 2004 to 200

51 In Cote d'Ivoire, the most prevalent HIV-1 subtype is CRF02

52 d current and novel monitoring strategies in Cote d'Ivoire, West Africa.

53 sus ST0 in Thailand, and 13.1% versus SC0 in Cote d'Ivoire.

54 to the entire community in four settings in Cote d'Ivoire.

55 surveillance system located in south-central Cote d'Ivoire.

56 Pan troglodytes verus) in Tai National Park, Cote d'Ivoire.

57 s conducted in the Taabo area, south-central Cote d'Ivoire.

58 2 research cohorts of HIV-infected adults in Cote d'Ivoire.

59 or HIV-1/2-infected blood donors in Abidjan, Cote d'Ivoire.

60 e-ranging sooty mangabeys in the Tai Forest, Cote d'Ivoire.

61 man immunodeficiency virus type 1 (HIV-1) in Cote d'Ivoire.

62 les, and 16 confirmed HIV-2 samples from the Cote d'Ivoire.

63 ctive and less costly than CD4 monitoring in Cote d'Ivoire.

64 ission, Registre des Hemopathies Malignes de Cote d'Or, and French Agence Nationale de la Recherche.

65 n 18-amino-acid stretch in the N-terminus of CotE direct the formation of CotE multimers, most probab

66 c mutants, we show in vitro and ex vivo that CotE enables binding of spores to mucus by direct intera

67 l stages of coat assembly a protein known as CotE forms a ring around the forespore.

68 However, the cotE gerE spores did retain a thin layer of insoluble co

69 In Bacillus subtilis, a coat protein called CotE guides the assembly of a major subset of coat prote

70 However, CotE has only a modest role in coat protein assembly, in

71 One of these, cotE, has a striking function in B. anthracis: it guides

72 simple disease-specific comorbidities index (COTE) helps assess mortality risk in patients with COPD.

73 dictor of mortality and explored whether the COTE index added predictive information when used with t

74 We tested the COTE index as predictor of mortality and explored whethe

75 Increases in the COTE index were associated with an increased risk of dea

76 icted mortality and were integrated into the COTE index.

77 In animal models of CDI, we show that when CotE is absent, both colonization and virulence were mar

78 pore surface; and (iii) interactions between CotE molecules depend on residues within an 18-amino-aci

79 e N-terminus of CotE direct the formation of CotE multimers, most probably homooligomers.

80 cotE mutant spores are fully virulent in animal models,

81 for infection, at least in the context of a cotE mutation.

82 of lacZ to the sporulation loci, spollA and cotE, of Bacillus subtilis were introduced into S. ureae

83 d studied the effects of altered versions of CotE on coat formation.

84 ding the subsequent positioning of a ring of CotE protein about 75 nm from the forespore surface.

85 beta-type small, acid-soluble protein or the CotE protein responsible for assembly of much spore coat

86 epitope, between amino acids 178 and 179 of CotE, reduced or prevented the assembly of several spore

87 t functions to maintain the integrity of the CotE ring and to anchor the nascent coat to the underlyi

88 , SpoVID, is required for maintenance of the CotE ring during the later stages, when most of proteins

89 A COTE score of greater than or equal to 4 points increase

90 e the following: (i) the reason decoated and cotE spores germinate poorly with dipicolinic acid is th

91 ng spore germination, and was not present in cotE spores in which the spore coat is aberrant.

92 We have used a series of mutant alleles of cotE to identify regions involved in outer coat protein

93 cid internal region involved in targeting of CotE to the forespore.

94 ter coat but did not prevent localization of CotE to the forespore.

95 idity index (COPD specific comorbidity test [COTE]) was constructed based on the comorbidities that i

96 Further, increases in the BODE and COTE were independently associated with increased risk o