ライフサイエンスコーパス: could

1 is attributed to the alphaI flexibility and could accommodate the alphaLbeta2-mediated rolling adhes

2 These benefits could accrue due to larger group sizes in general but al

3 Over longer timescales, CO2 release could act as a negative feedback, limiting progress of g

4 w future changes in temperature and salinity could affect the distribution and density of C. finmarch

5 e contrasting patterns of modulatory effects could allow PMd and PMv to play distinct functions for t

6 stem cell replacement, but other mechanisms could also be deployed, particularly in situations of hi

7 ough in the most general case, the technique could also be used to provide spatial selectivity with a

8 ct of both alpha- and gamma-cleavage events, could also induce TrkB phosphorylation.

9 ell adhesion, we hypothesized that radiation could alter the glycosylation pattern of endothelial cel

10 ling validated that this Ser-to-Arg mutation could alter the structure of the CDR3beta loop, as well

11 requires increased trophic efficiency, which could arise because of ocean warming and DSL shallowing.

12 ay therefore represent a new floral cue that could assist pollinators in the recognition and learning

13 asked whether activation of PZ(Vgat) neurons could attenuate or block the wake-promoting effects of t

14 nts and suggest that targeting this molecule could be a novel approach to treat allergic asthma.

15 dies suggest that this smart unimolecular NP could be a promising nanoplatform for targeted siRNA del

16 ity test demonstrates that the nanobiosensor could be a promising tool for specific evaluation of foo

17 thesized that the transcription factor PRRX1 could be a strong candidate gene as it is expressed in t

18 xidative, thiol and metal stress in bacteria could be a useful strategy to design new approaches to a

19 This model could be a useful tool for the olive industry to highlig

20 to antibiotic free milk samples and results could be accomplished within 5min.

21 These results could be accounted for by temperature-dependent changes

22 having a single canonical Galpha, this rate could be affected by regulatory proteins in the presence

23 o depends on intracellular Ca(2+) transport, could be affected by the loss of nBMP2.

24 To investigate whether such a mechanism could be an endogenous trigger for autoimmunity, we exam

25 Somatosensory connectivity could be an important target for recovery of hand functi

26 in the bending modulus of the bilayer which could be associated with the dissolution of ordered micr

27 Thymidine exudation could be attributed to ABCG36 function, whereas coumarin

28 ates of ESRD than HIV-positive whites, which could be attributed to the APOL1 renal risk variants.

29 screening of key HPVOPC associated molecules could be beneficial for early cancer diagnosis, monitori

30 Interestingly, the patients could be classified into two groups: those who were infe

31 in-13 is a powerful inotropic candidate that could be considered as an alternative noncatecholaminerg

32 These altered responses could be corrected in vitro by treatment with NKH-477, a

33 e nucleotide polymorphism-independent method could be crucial in dominant diseases that feature both

34 , to demonstrate this applicability, glucose could be detected in synthetic urine samples down to 1 m

35 or the biological data where SNVs and indels could be detected with very high sensitivity were 2.5 ng

36 for investigating brain glycosylation, which could be developed in to brain mapping applications, but

37 ealed that preclinical prostate tumor models could be differentiated according to hemosiderin iron ac

38 e standards, competent/noncompetent trainees could be discriminated in 94% of technical and 95% of no

39 , demonstrating that ABHD5 lipase activation could be dissociated from its other functions.

40 However, this bias could be driven by enhanced aversion to uncertainty abou

41 oxidant activity, its conversion to AChEI 2r could be easily achieved under mild conditions when incu

42 ry, categorical, or numerical attributes and could be easily extended to the analysis of massive netw

43 how pairings between long repeated sequences could be efficiently rejected even though most homologou

44 ts pomace, a by-product of juice processing, could be efficiently used for extraction of natural colo

45 have been calculated, and a 95% probability could be estimated at 2.0 kU/l.

46 in the kidney, we reasoned that FXR and TGR5 could be excellent candidates.

47 ulcus of the developing brain, those effects could be explained by patterns of neural activity that d

48 This effect could be explained by productive substrate binding that

49 in sediment and low concentrations in water could be explained via a hypothetical dynamic emission s

50 odulation of either HIPK2 levels or activity could be exploited to impair NRF2-mediated signalling in

51 sting that advances in long-term forecasting could be exploited to markedly improve management of fut

52 amental surface science implications, and it could be extended to other systems.

53 rahydropyran 4 the conformational equilibria could be frozen and assigned.

54 ies not amplified upon anti-PD-1 therapy and could be identified by a sustained coexpression of PD-1

55 al sites with BV <1.50 mV, and the remaining could be identified by corresponding low endocardial UV

56 Thirteen and 17 meaningful RSNs could be identified in PET and fMRI data, respectively.

57 ive science suggests that school achievement could be improved by preschool pedagogy in which numerat

58 r agreement is strong for some features, but could be improved for others.

59 rular synchrony was generally quite low, but could be increased by a factor of 4 by physiological lev

60 an objective of identifying key markers that could be investigated further to determine their usefuln

61 udying variation between places and services could be key to identifying targets for interventions to

62 Network analyses demonstrated that 51 traits could be linked through the linkage disequilibrium of 11

63 universal nonbiting genes in mosquitoes that could be manipulated as a means to control vector-borne

64 recruitment, no ligand-independent activity could be measured.

65 (PE) leads to increased addiction risk which could be mediated by enhanced excitatory synaptic streng

66 , decisive steps in such a ripening process, could be monitored through the NMR spectra.

67 sentially unexploited attractive interaction could be more broadly utilized as a tool not only in rel

68 oncardiac tissues; the cardiac abnormalities could be noninvasively captured by echocardiography, ele

69 PASMCs compared with wild-type PASMCs, which could be normalized by the application of hydrogen perox

70 t upstream of WNT3A, where WNT3A antagonists could be novel agents for the treatment of metastasis an

71 steps; however, both alpha and beta epimers could be obtained by a nonstereoselective approach start

72 n a single nanomagnet with vertical coupling could be of interest for magnetoresistive memories.

73 k as foldases under force, a mechanism which could be of relevance for several physiological processe

74 tational pathway assessment of a single cell could be of significant value for dissecting cellular he

75 opment of small molecules and biologics that could be of therapeutic use.

76 rkably, fertility of heterochromatin mutants could be partially restored by inhibiting cep-1/p53, end

77 These features could be particularly important when considering the int

78 if the proportion of animal tissue consumed could be predicted based on Na, N or net primary product

79 al response to different clusters in the PPA could be predicted by the similarity in their image prop

80 equently, light conveying perceptual content could be projected through the uterine wall and perceive

81 ld make sun protective behavior more likely, could be promoted and supported by school policies and p

82 On SPECT, (166)Ho could be quantified with high accuracy and precision, wi

83 e constructed an apparatus in which the food could be rapidly translated from the center of the arena

84 data that suggest that the uptake mechanism could be rather nonspecific The assay promises to be a p

85 rtantly, we demonstrated how proteomics data could be readily integrated with transcriptomics data in

86 MCLA-128 could be readily produced and purified at industrial sca

87 This niche disruption could be recapitulated by overexpressing upd3 and rescue

88 ary productivity in temperate forests, which could be reducing N availability.

89 morphology made of repeating LFAO units that could be regenerated upon sonication.

90 vary in different signaling pathways, which could be related to conformational selection, signaling

91 This basic structural information could be relevant for providing light on the mechanisms

92 Twenty-seven (46%) of these loci could be replicated in independent cohorts, underlining

93 eep-amount, but not sleep-timing, phenotypes could be reproduced or rescued by knocking out or restor

94 exhibit delayed wound closure in vivo, which could be rescued by topical IL-27 treatment.

95 d proliferation, and replication stress that could be rescued with an antioxidant.

96 ns contained within the 530 bp deletion that could be responsible for modulation of leukotoxin produc

97 However, translocation could be restored by alpha-helical domains in a position

98 The data presented here illustrate that UHRA could be safely used as an antidote during adverse thera

99 n changes were entered in a vGMS note, which could be seen by all clinicians.

100 In vivo, CL photoactivation could be shown by using the tumor-specific, integrin-tar

101 hains/number of norbornene backbone repeats) could be straightforwardly controlled by the macromonome

102 rleukin-1beta release, though this phenotype could be suppressed by pharmacological neutralization of

103 st that the neural basis of the decoy effect could be the context-dependent activation of the valuati

104 We agree with them that grooming styles could be transmitted by different mechanisms in differen

105 s-talk between alphaL alphaI and beta2 betaI could be uncoupled because the beta2 extension and headp

106 ggest that a previously abandoned antibiotic could be used again to treat a minority of gonorrhoea ca

107 y-driven measure of processing capacity that could be used as a biomarker of injury for outcome predi

108 The ligand could be used in a substoichiometric amount (0.25 equiv)

109 et important problem since such a prediction could be used to deduce not only a compound's possible a

110 gion that is characteristic of D. hamiltonii could be used to design specific assays, enhancing its a

111 The RuNPs/GC based DPV technique could be used to determine the concentration of uranyl i

112 molecular signature of radiation sensitivity could be used to identify the optimum radiotherapy dose.

113 the clinical benefit after chronic DBS that could be used to improve intraoperative neurophysiologic

114 ty and subsequent bony callus formation, and could be used to induce cartilaginous callus formation.

115 The ABMR prognostic score could be used to inform therapeutic decisions in clinica

116 ession of six potential reference genes that could be used to normalize gene expression and selected

117 lop an environmental-benign bio-measure that could be used to purify dye-contaminated wastewater.

118 is regulated and, with moderate throughput, could be used to screen for structural elements, small m

119 AT1RaAbs could be used to stratify patient risk and to identify p

120 Whether echinocandins could be used to treat candidemia of a urinary tract sou

121 le sclerosis suggests that depleting B cells could be useful for treatment.

122 enerally writable, erasable and mobile, they could be useful in functionally agile devices: for examp

123 mists to design novel dynamin ligands, which could be useful in the treatment of dynamin-related diso

124 The reaction could be viewed as an electron-transfer initiated reduct

125 ed that treatment and distribution processes could be viewed as ecological disturbances exhibited ove

126 SC) for ion-selective electrodes (ISEs) that could become the ultimate, generally applicable SC, whic

127 g-term efficacy is leading many patients who could benefit from drug therapy to not take these drugs.

128 dy identified vulnerable subpopulations that could benefit from targeted interventions.

129 ws of vulnerability when abnormal experience could cause lasting damage to the developing brain.

130 henotype, and that altering tumor metabolism could change therapeutic outcome.

131 Beverage consumption (i.e., tea or coffee) could clearly be seen in the data.

132 as functional experiments revealed that Spt6 could compete for binding of the PRC2 methyltransferase

133 trains arising through further gene deletion could compromise such a strategy.

134 show that OD Cu can reoxidize rapidly, which could compromise the accuracy of ex situ methods for det

135 ese results suggest a general mechanism that could contribute to immune-mediated diseases.

136 and suggest that disruption of this process could contribute to various deficits associated with alc

137 curs between different cellular environments could control beta-synuclein (betaS) aggregation via alt

138 g the substrate specificity of these enzymes could create opportunities for their biocatalytic use in

139 In summary, the piRNA-rich nict-1 locus could define a novel mechanism underlying phoretic inter

140 eta-annulus had been disrupted and that this could destabilize the capsid.

141 DNA probes on the test-zone), the biosensor could detect a minimum concentration of 0.4 fM DNA.

142 baseline total metabolic tumor volume (TMTV) could detect early relapse or refractory disease.

143 eased power to discover genetic variants and could elucidate shared molecular genetic mechanisms.

144 formation deliberately using ion irradiation could enable new electronic applications.

145 d environment-friendliness, these properties could enable new kinds of electrically driven entirely s

146 This assay could enable specific diagnosis of ZIKV infection over o

147 ond high oxidation state 5f metals and hence could encompass mid-range oxidation state actinides and

148 of miR-146b combined with stem cell therapy could enhance regeneration of cartilaginous tissue and s

149 l chemistry on the compounds' basic scaffold could enhance the potency and selectivity for ALDH1A1 or

150 e PI, Karachi (Pakistan) and Kolkata (India) could expect conditions equivalent to their deadly 2015

151 Surrogates for overall survival (OS) could expedite the evaluation of new adjuvant therapies.

152 s a modifiable factor in multiple disorders, could explain any of these associations.

153 d on the expression of AE3 in neurons, which could explain how AE3 reduces seizure susceptibility.

154 300 acetylated in its activation loop, which could explain self-acetylation as an important feedback

155 anulopoiesis, this new immunomodulatory role could explain the protection conferred by THP during AKI

156 ases by ordering the disordered phase, which could explain their role in cell membranes.

157 he biological and analytical techniques that could facilitate a precision medicine approach for ARDS.

158 what is an early lethal mutation in mammals could facilitate improvement of diagnostics and therapeu

159 quently, such specific fusion toxin proteins could form the basis of a therapeutic strategy for elimi

160 the rotation rate of individual amino groups could give insight into the dynamic processes occurring

161 fficiency of the biological carbon pump that could have accounted for as much as half of the glacial-

162 flammation in the lungs of the sanroque mice could have been influenced by emerging autoimmune condit

163 l function and endoplasmic reticulum stress, could have contributed to the neutral trial results in R

164 V and why specifically targeting prefusion F could have great clinical potential.

165 ring immediate intervention and that led (or could have led) to major disability or death.

166 natural and ancient origin of organohalogens could have primed development of metabolic machineries f

167 Therefore, changes in these sources could have significant implications for global warming.

168 Preclinical multiparametric diagnostics could help discover clinically relevant biomarker combin

169 orm rapidly under oxidized conditions, which could help explain low concentrations of organics within

170 ate sector, as well as in the public sector, could help identify the majority of missing cases.

171 tibiotic use and suggest that such practices could help reduce the load of antibiotic-resistance gene

172 cated in Symbiodinium cells in hospite, they could help to explain the breakdown of the coral-Symbiod

173 onitoring and point-of-care resistance tests could help to mitigate the emergence and spread of such

174 or 4.5 kg (10 lbs) without a controller and could hold up to 1100 bar (16000 psi) of pressure.

175 bolism and in the endoplasmic reticulum that could impact viral entry and replication.

176 intravenously (IV) administered calcimimetic could improve adherence and reduce adverse gastrointesti

177 estimate the internal model before movement could improve motor neural prostheses being developed fo

178 NA signature associated with HLA class I-DSA could improve our understanding of ABMR and be useful fo

179 ralizing similar cases of negative epistasis could improve productivity in many agricultural organism

180 ity in the spinal cord during chronic stroke could improve recovery from persistent sensorimotor impa

181 er mortality rates and that these biomarkers could improve risk stratification of poor outcomes.

182 regulatory requirements for reporting spills could improve the accuracy and speed of analyses to iden

183 n signatures and candidate therapeutics that could improve the treatment of metastatic neuroblastoma.

184 rognosis, and innovative maintenance therapy could improve their outcomes.

185 ies paper, we explore several new ideas that could improve understanding of the phenotypic and genoty

186 ion of inactivated poliovirus vaccine (fIPV) could increase IPV affordability and stretch limited sup

187 Surviving DPCs could increase the availability of neurotrophic factors

188 and increase retention of HSCs in the liver could increase their antifibrotic activities and be deve

189 ures make the highly sensitive sensors which could indicate very low detection limit to the level of

190 eposition and temperature sensitivity, which could influence C storage under combined anthropogenic g

191 hain between these complex phenotypes, which could inform and prevent disordered eating problems in a

192 hould be further explored, as this knowledge could inform paediatric treatment decisions.

193 own factors and spending increases over time could inform policy efforts to contain future spending g

194 kinase may represent a potential target that could interrupt the enzymatic activation of the caspase

195 owed by dehydrosulfurization and guanylation could lead to both symmetric and unsymmetric N,N',N''-su

196 In contrast, warm temperatures without FTCs could lead to divergent responses in soil bacteria and t

197 of trophoblast-specific GATA2/GATA3 function could lead to early pregnancy failure.

198 Further development of this approach could lead to fast and automated purification of DNA nan

199 f electronically excited BODIPY chromophores could lead to further advances in these areas.

200 se the likelihood of biomarker discovery and could lead to more comprehensive understanding of diseas

201 hanisms that underlie restless legs syndrome could lead to new treatment options.

202 rties of monolayer two-dimensional materials could lead to novel multi-functionalities.

203 axis with its specific and potent inhibitors could lead to promising host-directed therapeutic adjuva

204 of this study include measurement error that could lead to residual confounding; and the possibilitie

205 reduce both tumor size and invasiveness and could lead to tumor eradication.

206 ntelligences learn things that no individual could learn in a lifetime.

207 Thus, we showed that rhesus monkeys could learn to categorize on the basis of implied ordina

208 wering the total amount of drug administered could lower toxicities while not compromising on the eff

209 xample, creating and moving conducting walls could make or break electrical connections in new forms

210 Using UV-vis spectroscopy, we could measure the amount of Fe(3+) in the sample solutio

211 Tandem MS/MS experiments showed that DMSO could modify the dissociation pathway of CYP142A1, while

212 However, this same processing technique could most likely be applied to any low photon-number im

213 donor-acceptor dyads, but their involvement could never be unambiguously evidenced spectroscopically

214 This difference could not be accounted for by differences in running spe

215 Activity could not be detected for a range of putative para-hydro

216 ty; however, several patient-level variables could not be included in our analysis because of high le

217 ey was slightly enlarged and the left kidney could not be localized.

218 d-run" model and transcription bursting that could not be obtained by in vitro biochemistry analysis.

219 For SAR that could not be rationalized through the cocrystal complex,

220 Migration could not be rejected in any population, but required ra

221 discontinuation; predictors of poor response could not be reliably identified.

222 cells arose from vascular-resident beds that could not be transferred by bone marrow transplantation.

223 We could not establish the proportion of casualties caused

224 Although MUTT II could not find a benefit for all corneal ulcers, Fusariu

225 dialysis method, we found that H9e hydrogel could not significantly inhibit the diffusion of camptot

226 se the beta2 extension and headpiece opening could occur independently of the alphaI activation.

227 a significant reduction of US sodium intake could occur.

228 suppress virus proliferation, this approach could offer a new strategy for the development of HIV in

229 dings suggest that fluorescence spectroscopy could offer a rapid and high-throughput screening method

230 rtant implications for organismal health and could offer new therapeutic approaches for neurodegenera

231 eliable detection of short RNA regions which could open up new opportunities in transcriptome analysi

232 thus, the only subunits of ATP synthase that could participate in pore formation are e, f, g, diabete

233 x state, hence suggesting that the H channel could play a more general role as a dielectric well.

234 We thus hypothesized that dlBST could play a role in LID hyperkinetic manifestations.

235 ection, the dialogue between these two areas could play a role in the regulation of emotions and in p

236 native, politically unbiased yield estimates could play in understanding policy impacts.

237 regions and cross-reactive antibodies (Abs) could potentially affect ZIKV pathogenesis.

238 Lyme disease spirochetes within tick vectors could potentially aid development of novel methods to co

239 t the heart of some forms of infertility and could potentially be addressed therapeutically by altern

240 lk between nerves and endothelial metabolism could potentially be targeted as an anticancer therapy.

241 uman participants and makes predictions that could potentially be tested with neurophysiological reco

242 Induced pluripotent stem cells could potentially help to elucidate the complex mechanis

243 monstrate that co-targeting of ROS1 and EGFR could potentially offer an effective oral cancer therapy

244 ates that appeared to accumulate pyrin; this could potentially precipitate inflammasome assembly.

245 notype, genotype-differentiating metabolites could potentially predict IBD risk.

246 e cells will be disinhibited; and thus, this could potentially result in increased reward.

247 nd to be of limited clinical relevance, they could potentially serve as reservoirs of antimicrobial r

248 nce increasing the Vif-Pr55(Gag) interaction could potentially suppress virus proliferation, this app

249 id classification models were developed that could predict solubility-enhancing mutations that mainta

250 ith sufficient data to evaluate whether CR30 could predict treatment effects on PFS.

251 eligible US adults, intensive SBP treatment could prevent approximately 107 500 deaths per year.

252 time, and therefore, reconnecting fragments could prevent species losses and allow locally extinct s

253 perception that the coexistent coagulopathy could promote bleeding.

254 be speculated that this pair of side chains could promote oligomerization of kalata B1 through elect

255 [PSI+] variants requiring Arg82p could propagate in ipk1Delta (IP5 kinase), kcs1Delta (IP

256 ons, suggesting that the structured neuropil could provide a framework for the development of E/I bal

257 Restoration of let-7 expression could provide a new target for an anti-inflammatory appr

258 n if events are under recorded, this measure could provide an easily understandable and useful baseli

259 ti-use and single use intermittent catheters could provide users with more flexible choices in self-c

260 ze tools that offer new modes of control and could realistically contribute to operational control in

261 Both groups could receive open-label LAI for 84 additional days.

262 Alternatively, wild pollinators could recognize an exclusive signature of cues unique to

263 By shifting the light window, we could reconstruct PPI time-courses.

264 demonstrated that demanding cognitive shifts could recruit the DMN, yet it is unknown whether this ho

265 longer therapy-ie, the short-course regimen could reduce incidence by 23% (10-38).

266 d (i) whether systematic localisation errors could reflect reliance on prior knowledge, as has been p

267 In addition, we verified miR-449b could regulate the expression levels of CDK6, c-MYC, HDA

268 l phenotype seen in syndromic USH2A patients could relate to a greater extent of cone dysfunction.

269 nt starting seed densities showed that seeds could replace other more labour intensive and costly met

270 that a tumor has increased in size, but this could represent pseudoprogression.

271 resent two semi-independent populations that could require separate management consideration for thei

272 All cloned AHAs could restore immune effector functions to proteolytical

273 catalyzes processive repeat synthesis, which could restore the full 100 nucleotides of (T2AG3)n lost

274 teroids, and to model potential savings that could result from substitution of the cheapest topical s

275 1-weighted and diffusion-weighted MR imaging could reveal imaging biomarkers associated with cognitio

276 studies further demonstrate that these loops could serve as excellent targets for designing anti-CVA6

277 These could serve as intronic splicing enhancers.

278 fication of APOL1-interacting molecules that could serve as new drug targets to treat APOL1-associate

279 inflammatory states may be revealed and this could serve as novel pharmacological targets for the tre

280 latently infected cells by productive virus could similarly remove those cells through active virus

281 ven if the Paris targets are realized, there could still be a significant adaptation imperative for v

282 This strategy could strengthen the evidence base to enable black women

283 -type ribosomes, and the elaborated proteins could subsequently be deprotected by photolysis.

284 glion cells in regular cannabis users, which could support alterations in vision.

285 ignature" observed in patients with IgG4-RD, could support diagnosis and treatment monitoring.

286 of an effective maternal HIV-1 vaccine that could synergize with antiretroviral therapy (ART) to eli

287 sign of maternal vaccination strategies that could synergize with ART during pregnancy to achieve the

288 orphism with a liquid-liquid transition that could take place in the no-man's land, the temperature-p

289 mer, Broccoli, into two split fragments that could tandemly bind to target mRNA.

290 findings establish that EVs secreted by AFSC could target a specific signaling pathway within the glo

291 r matching-to-sample training, and that they could then make inferences about category order.

292 cessibility between developmental stages and could thereby represent putative enhancers.

293 coupled to an energy transduction step that could thermodynamically drive proton pumping in complex

294 Could this 'stroke paradox' be a result of the increased

295 Prostratin and bryostatin-1 could thus be considered as potent regulators of BBB per

296 eroidal anti-inflammatory drugs (NSAIDs) use could trigger acute myocardial infarction (AMI).

297 hat the pore structure of many mineral soils could undergo N-dependent changes as atmospheric CO2 con

298 clocks may be regulated by feeding time and could underpin plasma glucose changes.

299 dispersed by sifting (regardless of sifter) could unintentionally mix other foods.

300 ed phenomenon that P2Y1R antagonism patterns could vary in different signaling pathways, which could