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1 Claisen rearrangement of a 1,1-dimethylallyl coumarin.
2 ties should enhance biological properties of coumarin.
3 Interface into MS, confirmed the identity of coumarin.
4 site of binding for the most potent sulfated coumarin.
5 echanisms by alkyl adenylates and diarylated coumarins.
6 ydroxy aromatic aldimines with 3-substituted coumarins.
7 of inhibitors when compared to isostructural coumarins.
8 molecular Friedel-Crafts reaction of benzo[f]coumarins.
9 technological and biochemical importance of coumarins.
10 n unsymmetrical product derived from the two coumarins.
11 chemical properties and possible toxicity of coumarins.
12 biologically important pi-electron extended coumarins.
13 ghly oxygenated rather than monohydroxylated coumarins.
14 ion of (E)-cinnamic acid analogues to afford coumarins.
17 differently sized luminescent guests, namely coumarin 1, coumarin 4, fluorescein, [Ru(bpy)3 ]Cl2 , an
20 toinduced electron transfer dynamics between coumarin 153 (C153) and 4,4'-dimethyl viologen dichlorid
21 hyl-6-propionyl-2-naphthylamine (prodan) and coumarin 153 (C153) in a series of toluene/dimethyl sulf
23 ved fluorescence experiments with photoacids coumarin 183 and equilenin show the active site of Delta
24 Photoexcitation of a fluorescent analog (coumarin 183) of the reaction intermediate mimics the ch
25 marin 343, after receiving energy from donor Coumarin 2 emitted higher fluorescence intensity than wh
26 ceptor Coumarin 343 in the core to the donor Coumarin 2 on the periphery, and the average distance be
27 n efficient energy transfer from the excited Coumarin 2 to the ground-state Coumarin 343 in the core,
29 presentative library of 3,5,8-trisubstituted coumarins (21 compounds, 7 families, 3 groups) is descri
31 capsulated neutral red were produced using a coumarin 3-carboxylic acid conjugated poly(sodium N-unde
32 t AND molecular logic gates are based on the coumarin-3-aldehyde scaffold and designed to give a turn
33 weight carbonylated LPP with 7-(diethylamino)coumarin-3-carbohydrazide (CHH) and analyze all compound
34 We present here the inhibitory properties of coumarin-3-carboxylate derivatives against these enzymes
35 2-ethylpyrrole, and 2-methylallylsilane) to coumarin-3-carboxylates has been developed to afford chr
36 t reaction was designed by bringing together coumarin-3-carboxylates with indoles and amines to affor
37 eaction is developed using readily available coumarin-3-carboxylic acids and aldehydes as reactants u
40 electron-rich phenols reacted with esters of coumarin-3-carboxylic acids, leading to substituted chro
41 ons in the intracellular environment using a Coumarin 343 (C343)-conjugated drug and hmKeima8.5 as a
42 tachment of 4-nitrophenyl-acetylacetonate or coumarin 343 adsorbates, exhibit hole injection into sur
43 for example, the molar ratio of the acceptor Coumarin 343 in the core to the donor Coumarin 2 on the
44 m the excited Coumarin 2 to the ground-state Coumarin 343 in the core, with the efficiency of the ene
47 of the interfacial electron transfer between Coumarin 343, a solar cell sensitizer, and TiO(2) nanopa
49 on transfer from the photoreduced sensitizer Coumarin-343 (C343) to complex 1, both bound on the surf
50 cyanins make up 16.5%, phenolic acids 43.3%, coumarin 36.2% and flavonoids 4% of total compounds.
51 sized luminescent guests, namely coumarin 1, coumarin 4, fluorescein, [Ru(bpy)3 ]Cl2 , and rhodamine
52 gher sensitivity than conventional 7-methoxy-coumarin-4-yl acetic acid (MCA)/Lys(DNP) substrates; thu
53 We present the synthesis of [7-(diethylamino)coumarin-4-yl]methyl (DEACM)-caged phosphorylated serine
55 ovement in the sensitivity of the signal for coumarin 47 when the plasma was used to ionize the dye u
57 on and removal of the 7-hydroxy group led to coumarin 59, which had increased potency and improved ra
58 ells catalyzed the coupling of the monomeric coumarin 7-demethylsiderin both regio- and stereoselecti
59 efficiency with 7-ethoxy-4-(trifluoromethyl)coumarin (7-EFC), followed by 7-methoxy-4-(trifluorometh
62 NOO(-) with the aid of boronate probes, e.g. coumarin-7-boronic acid or 4-boronobenzyl derivative of
64 elum minutum leaves together with four known coumarins, 8,4''-dihydroxy-3'',4''-dihydrocapnolactone-2
66 s containing ethanol are correlated with the coumarin absorbances in summer, winter and spring wherea
67 l monomers based on different aminoacids and coumarin allowed isolation of polymers with very good re
68 n their rates of hydrolysis of 5-aminomethyl coumarin (AMC) from C-terminally labeled peptide, ubiqui
69 hromenes were converted to the corresponding coumarin analogues by a pyridinium dichromate (PDC)-medi
73 ate, which is glycosidically conjugated to a coumarin and a linker containing a tert-butyloxycarbamid
76 y of the immobilized CYP2A6-FLD, toward both coumarin and nicotine substrates, by tranylcypromine, a
77 Experimental results indicated that both coumarin and p-chlorobenzoic acid are oxidized via direc
78 f the ratio of fluorescence intensities from coumarin and the NBD-Cys or NBD-Hcy adducts generates a
79 ted ground state for the cation, whereas for coumarin and xanthenyl cations substituted with strong d
80 iolamides in formation of 3-organoselenyl-2H-coumarins and 3-organoselenyl-quinolinones, respectively
82 a are those producing cyanogenic glycosides, coumarins and benzofuranocoumarins, being predominantly
84 ification of small molecules (coumarins, iso-coumarins and pyrido-pyrimidinones) that modify the alte
87 2] photocycloaddition of three 4-(alk-4-enyl)coumarins and three 1-(alk-4-enoyl)-2,3-dihydropyridones
88 o-3-((((2-iodoacetamido)ethyl)amino)carbonyl)coumarin, and introduced into permeabilized rabbit psoas
89 center are derived from alkylidene oxindole, coumarin, and malonate substrates with high stereoselect
90 aimed to quantify the levels of resveratrol, coumarin, and other bioactives in pulps and by-products
91 alkoxycoumarins, 7-alkoxy-4-(trifluoromethyl)coumarins, and 7-alkoxy-4-methylcoumarins-with a C1-C7 s
92 s, flavonoid aglycones, C- and O-glycosides, coumarins, and lignans) in plant extracts was developed,
96 first time, a study was performed to compare coumarin- and chomone-3-phenylcarboxamide scaffolds.
99 ta-arrestin assays to identify 3-substituted coumarins as a novel class of antagonists and performed
100 Arabidopsis plants release Fe(III)-chelating coumarins as part of the strategy I-type Fe acquisition
101 ,8-naphthalimides, fluoresceins, rhodamines, coumarins, azo-dyes, oxadiazoles, diverse aromatic dyes
102 the C-S bond coupling reaction by applying a coumarin-based fluorogenic probe in bacterial lysates.
104 rt the synthesis and evaluation of optimized coumarin-based inhibitors with 9-18-fold increased poten
105 of organic host materials, we synthesized a coumarin-based ligand that was cyclometalated onto an ir
106 were assembled by first binding photolabile coumarin-based molecules to the nanoparticle surface.
108 ic (EO) chromophore with covalently attached coumarin-based pendant groups exhibits intermolecular co
112 from droplets, no exchange of the sulfonated coumarins being detected over 24 h at 30 degrees C.
114 r their ability to transport the fluorescent coumarin beta-glucoside esculin when expressed in yeast.
115 er treatment, the distribution of individual coumarins between roots and exudates in the investigated
116 orted structure of a 2OGD enzyme involved in coumarin biosynthesis and closely resembles the structur
117 ic approach has been utilized to emulate the coumarin biosynthesis pathway, which features a key phot
118 droethidine, hydropropidine, Amplex Red, and coumarin boronate) with well defined redox chemistry tha
119 this study, we show that the profluorescent coumarin boronic acid (CBA) probe reacts with amino acid
123 r electron transfer quenching of a series of coumarins by N,N-dimethylaniline was investigated using
124 cesses of p-type NiO films cosensitized with coumarin C343 and a bioinspired proton reduction catalys
125 synthesis and photochemical properties of a coumarin-caged cyclic RGD peptide and demonstrate that u
127 compounds incorporating 6- and 7-substituted coumarins (carbonic anhydrase, CA inhibitors) derivatize
129 arison of the kinetic parameters showed that coumarin catalysis was carried out with a higher efficie
131 have demonstrated that the structure of the coumarin chromophore influences the rate of the uncaging
132 previously described hydroperoxide-sensitive coumarin-conjugated phosphine probe to enable rapid quan
135 roup (VMAT recognition), halogenated hydroxy-coumarin core (ratiometric optical pH sensing in the des
136 phosphate analogues bearing 7-(diethylamino)coumarin (DECM) and 4-bromo-5-hydroxy-2-nitrobenzhydryl
137 veral analogs, including a C-terminus-linked coumarin derivative (22) that exhibited appreciably incr
138 anidin, Cya), the interaction of Glia with a coumarin derivative (3-ethoxycarbonylcoumarin, 3-EcC), h
140 effect of a methyl group incorporated in the coumarin derivative near the ester bond linking both moi
142 nt years, several laboratories have used the coumarin derivative, 4-methylumbelliferone, as a potent
146 Gs, the emission of the mononitro-containing coumarin derivatives in the red region upon excitation w
147 cterized the inhibition of four psoralen and coumarin derivatives toward ALDH2 and compared them to t
148 dition of gamma-butyrolactam onto the 3-acyl coumarin derivatives was observed rather than the gamma-
149 um graminearum and Fusarium verticillioides, coumarin derivatives were proven to possess a very high
151 Two new ligands, out of a library of 17 coumarin derivatives, were identified, and the half-maxi
152 d as templates for docking the 7-substituted coumarin derivatives, which revealed orientations consis
153 In the first type of micelles, hydrophobic coumarin-derived dyes were encapsulated noncovalently in
155 ization led us to discover a novel series of coumarin-dihydropyridine hybrids that have potent osteob
160 onyl of the lactone function of the original coumarin dyes has been replaced by the cyano(4-nitrophen
161 Its molecular structure is related to known coumarin dyes that could be used as lead chromophore anc
162 Photon counts and optical fluctuations from coumarin encoded within TRPV1 tetramers correlates with
165 ld be attributed to ABCG36 function, whereas coumarin exudation was strongly reduced only in ABCG37 d
167 al libraries and consequently developed a di-coumarin family of inhibitors that preferentially inhibi
168 nd a number of anthocyanins, phenolic acids, coumarins, flavanols, dihydrochalcones and flavonols wer
171 hich can catalyze the covalent ligation of a coumarin fluorophore onto a peptide recognition sequence
172 rmally unfolded protein and a thiol-specific coumarin fluorophore that is only fluorescent upon conju
174 te group effectively prevents leakage of the coumarin from droplets, no exchange of the sulfonated co
175 olomic strategies; the OHC fraction includes coumarins, furocoumarins, and polymethoxylated flavonoid
176 efficient procedure for the synthesis of bis-coumarins fused at the pyranone ring has been developed.
177 t we tested, naturally occurring fluorescent coumarin glucosides (esculin and fraxin) were phloem loa
179 es revealed that 5-hydroxy-naphtho[2,1,8-def]coumarin has the most bathochromically shifted both abso
180 nent tandem synthesis of 3-N-sulfonylamidine coumarins has been accomplished by the coupling of salic
181 egioselective synthesis of naphtho[2,1,8-def]coumarins has been realized through a concise route that
184 ies of novel tacrine derivatives and tacrine-coumarin heterodimers were designed, synthesized, and bi
186 hyl ester); (ii) locally photolyzing a caged coumarin in one cell of a coupled cell pair to release t
187 in guava and surinam cherry by-products and coumarin in passion fruit, guava and surinam cherry by-p
195 ently the identification of small molecules (coumarins, iso-coumarins and pyrido-pyrimidinones) that
200 bstituted phenylboronic acids to replace the coumarin lactone of 2, we identified that electronegativ
202 mber of solutes per vesicle as a function of coumarin:lipid ratio and average number of solutes per v
203 The site-specific incorporation of three new coumarin lysine analogues into proteins was achieved in
207 mino-3-((((2-maleimidyl)ethyl)amino)carbonyl)coumarin (MDCC) to a cysteine introduced at residue 212,
210 assay-guided isolation, two new monoterpene coumarins, minutin A and minutin B, were purified from M
212 switchable DNA cross-linking reaction of the coumarin moieties can potentially serve as mechanistic p
213 s-link (ICL) formation was observed with the coumarin moieties containing a flexible two-carbon or lo
214 coordinate a K(+) ion in the pore with their coumarin moieties, whereas the hydrophobic phenoxyalkoxy
215 ced [2 + 2] cycloaddition occurs between the coumarin moiety and the thymidine upon 350 nm irradiatio
216 oncovalently associated with the substituted coumarin molecule, blocking the pores and preventing the
218 gn principle is based on a nitrobenzofurazan-coumarin (NBD-Coum) construct, which fragments into spec
221 the adaptation of a 7-ethoxytrifluoromethyl coumarin O-deethylation fluorescence activity assay to a
222 hylase (EROD), benzyloxy-4-[trifluoromethyl]-coumarin-O-debenzyloxylase (BFCOD), and 7-ethoxycoumarin
223 ner of interest, LplA(W37V) labels LAP1 with coumarin only when the protein partners to which they ar
224 inescent lanthanide (Ln(III)) complexes with coumarin or carbostyril antennae were synthesized and th
225 hod conducted through the reaction of either coumarins or coumarin-3-carboxylic acids with aromatic a
228 igated the suitability of four OH(*) probes (coumarin, p-chlorobenzoic acid, terephthalic acid, and p
230 ino-3-((((2-maleimidyl)ethyl)amino)carbonyl) coumarin) placed at the same positions, which suggests a
231 ad of an alkyne as reaction partner leads to coumarin products which formally result from a (5 + 1) c
233 constitutive concentrations of bark lignans, coumarins, proline, tyramine and defensive proteins, and
235 The mechanistic course of the uncatalyzed coumarin reactions was found to be a singlet pathway, wh
239 is paper, we have designed and synthesized a coumarin-rhodamine (CR) TBET system and demonstrated tha
240 ation show that the functionalization of the coumarin ring results in a strong red-shift from 330 to
242 tors has been time-consuming, we synthesized coumarin-SAHA (c-SAHA) as a fluorescent probe for determ
243 s of push-pull chromophores based on a novel coumarin scaffold in which the carbonyl of the lactone f
245 ess, opening the way to exploiting these new coumarin scaffolds as caging groups that can be removed
246 nthesis of benzothiazole-tethered chromanone/coumarin scaffolds via Claisen rearrangement using a sol
247 llfully embraced with oxindole, pyrrole, and coumarin scaffolds, which are well-known for their enric
250 s including phenolic compounds, of which the coumarin scopoletin (7-hydroxy-6-methoxy-2H-1-benzopyran
253 identification of a 4,6-diaryl-5,7-dimethyl coumarin series that kills M. tuberculosis by inhibiting
255 ng based on quantifying 18 furocoumarins and coumarins, some of which are regulated by law, and (ii)
256 route for the construction of functionalized coumarin structural frameworks in a single operation wit
257 was impaired in the presence of the sulfated coumarins suggesting that allosteric partial inhibition
258 between a set of drugs (i.e., indomethacin, coumarin, sulfadymethoxine, warfarin, and salicylic acid
259 substrates including cinnamates, crotonates, coumarins, sulfones, and chalcones were successfully fun
261 ciple, we attached four different length PEG-coumarin tags to the terminal phosphate of 2'-deoxyguano
263 required for the biosynthesis of fluorescent coumarins that are released into the rhizosphere, some o
264 lator 2-isocyano-6,7-dihydroxycoumarin (ICDH-Coumarin) that directly senses and modulates environment
267 This versatility in the binding mode of coumarins/thioxocoumarins has important consequences for
269 ioanalytical tool for risk assessment showed coumarin to be active against Aliivibrio fischeri bacter
270 e reported targeting of the blue fluorophore coumarin to cellular proteins fused to a 13-amino acid r
271 ak arises from one-electron reduction of the coumarin to form a radical-anion intermediate, which is
272 usion complexes facilitate the conversion of coumarin to its anti-head-to-head (HH) photodimer with h
273 ation at 800 nm cleaves the bond holding the coumarin to the nanopore, releasing both the CD cap and
274 esized a focused library of some 36 sulfated coumarins to discover two agents that display sub-maxima
276 ated regioselective C-H functionalization of coumarins toward expedient synthesis of 3-aroyl coumarin
279 ng, the fluorescent non-canonical amino acid coumarin-tyrosine was genetically encoded at Y671, a res
280 olecular orientations of the chromophore and coumarin units are also evident when investigated optica
281 roups exhibits intermolecular correlation of coumarin units through molecular dynamics (MD) simulatio
282 Here we present delivery of a fluorescent coumarin using a cobalt(III) chaperone to target hypoxic
284 ng from assembly of the suitably substituted coumarin via the Pechmann reaction of 2-naphthols with a
287 The specificity of ABCG37 for individual coumarins was further verified by a targeted LC-MS based
291 observed upon the solid-state irradiation of coumarin, which affords photodimers with low selectivity
292 ICL formation quenches the fluorescence of coumarin, which, for the first time, enables fast, easy,
293 photocycloaddition of 4-alkenyl-substituted coumarins, which led to the corresponding products with
294 fferent from the one observed for hydrolyzed coumarins, which occlude the entrance of the active site
295 hesis of flagella and the iron chelator ICDH-Coumarin whose production requires the pvc cluster.
296 e intermolecular [2+2] photocycloaddition of coumarin with tetramethylethylene mediated by thiourea c
297 ctron-deficient phenolic acetates, affording coumarins with excellent regioselectivity, and proceeds
298 , including chalcones, pyrazoles, chromones, coumarins, xanthines, isatin derivatives, thiazolidindio
299 the oxidative debenzylation of a substituted coumarin, yielding an increase in fluorescence on reacti
300 m hydroxide solution resulted in fluorescent coumarin zones, measured at 365/>400nm after stabilizati
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